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Showing 1-30 of 580 results for "21049" within Papers
Sachio Yamamoto et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 35(3), 295-300 (2018-11-06)
An analytical method for concurrent analysis of inorganic anions and cations has been developed using a capillary electrophoresis (CE)-capacitively coupled contactless conductivity detector (C4D) system. Although hydrodynamic and electrokinetic injection techniques have been widely used in CE, we employed a
Fei Ma et al.
Meat science, 95(1), 22-26 (2013-05-07)
The effects of high pressure processing (HPP) on the water-binding capacity and texture profile (TPA) of salt-soluble meat protein (SSMP) containing 0.2% CaCl2 and 0.6% κ-carrageenan (SSMP-CK) gels were investigated. The results showed that 300-400 MPa improved water-binding capacity and
Abaid Malik et al.
Basic & clinical pharmacology & toxicology, 116(1), 47-52 (2014-06-05)
The antifungal ionophore nystatin dissipates the Na(+) and K(+) gradients across the cell membrane, leading to cellular gain of Na(+) and cellular loss of K(+) . The increase of cellular Na(+) concentration may result in Ca(2+) accumulation in exchange for
Hirotada Hirama et al.
Langmuir : the ACS journal of surfaces and colloids, 29(2), 519-524 (2012-12-14)
We report a simple method for forming monodispersed, uniformly shaped gel microbeads with precisely controlled sizes. The basis of our method is the placement of monodispersed sodium alginate droplets, formed by a microfluidic device, on an agarose slab gel containing
Gimano D Amatngalim et al.
Journal of immunology (Baltimore, Md. : 1950), 194(7), 3340-3350 (2015-02-26)
Basal cells play a critical role in the response of the airway epithelium to injury and are recently recognized to also contribute to epithelial immunity. Antimicrobial proteins and peptides are essential effector molecules in this airway epithelial innate immunity. However
Temmei Ito et al.
Biomedical materials (Bristol, England), 10(1), 015025-015025 (2015-03-03)
In order to obtain a hydroxyapatite (HAp)-poly(ethylene glycol) (PEG) composite, tetra amine-terminated PEG was crosslinked using disuccinimidyl tartrate to obtain a PEG hydrogel. Using two kinds of chelators with different stability constants for Ca ion (N-(2-hydroxyethyl) ethylenediamine-N,N',N'-triacetic acid (EDTA-OH, 8.14)
Daniela Sieghart et al.
Journal of cellular and molecular medicine, 19(1), 187-197 (2014-10-15)
Balneotherapy employing sulphurous thermal water is still applied to patients suffering from diseases of musculoskeletal system like osteoarthritis (OA) but evidence for its clinical effectiveness is scarce. Since the gasotransmitter hydrogen sulphide (H2 S) seems to affect cells involved in
Christof Kaltenmeier et al.
Journal of immunology (Baltimore, Md. : 1950), 194(8), 3768-3777 (2015-03-18)
IL-21 can induce both plasma cells and regulatory B cells. In this article, we demonstrate that untreated HIV patients display CD4(+) T cells with enhanced IL-21 expression and high in vivo frequencies of regulatory B cells overexpressing the serine protease
Eagleson M.
Concise Encyclopedia Chemistry, 887-887 (1994)
Aurélie Ginisty et al.
Stem cells (Dayton, Ohio), 33(2), 515-525 (2014-10-14)
Neural stem cells, whose major reservoir in the adult mammalian brain is the subventricular zone (SVZ), ensure neuropoiesis, a process during which many generated cells die. Removal of dead cells and debris by phagocytes is necessary for tissue homeostasis. Using
Tilen Koklic et al.
The Biochemical journal, 467(1), 37-46 (2015-01-13)
Exposure of phosphatidylserine (PS) molecules on activated platelet membrane surface is a crucial event in blood coagulation. Binding of PS to specific sites on factor Xa (fXa) and factor Va (fVa) promotes their assembly into a complex that enhances proteolysis
Hana Sharaf et al.
Biochimica et biophysica acta, 1852(3), 429-441 (2014-12-17)
Diabetic patients have increased likelihood of developing breast cancer. Advanced glycation endproducts (AGEs) underlie the pathogenesis of diabetic complications but their impact on breast cancer cells is not understood. This study aims to determine the effects of methylglyoxal-derived bovine serum
Tarun Agarwal et al.
International journal of biological macromolecules, 75, 409-417 (2015-02-15)
The present study delineates preparation, characterization and application of calcium alginate (CA)-carboxymethyl cellulose (CMC) beads for colon-specific oral drug delivery. Here, we exploited pH responsive swelling, mucoadhesivity and colonic microflora-catered biodegradability of the formulations for colon-specific drug delivery. The CA-CMC
A Marijne Heeren et al.
BMC developmental biology, 15, 4-4 (2015-01-22)
In society, there is a clear need to improve the success rate of techniques to restore fertility. Therefore a deeper knowledge of the dynamics of the complex molecular environment that regulates human gametogenesis and (early) folliculogenesis in vivo is necessary.
Masoud M Ardestani et al.
Environmental pollution (Barking, Essex : 1987), 246, 19-25 (2018-12-12)
The aim of this study was to assess the effect of major cations (Ca2+, Mg2+, Na+, K+, and H+) on cadmium toxicity to the springtail Folsomia candida. Survival of the animals was determined after seven days exposure to different cadmium
Maja Genheden et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(3), 972-984 (2015-01-23)
Although the MAP kinase-interacting kinases (MNKs) have been known for >15 years, their roles in the regulation of protein synthesis have remained obscure. Here, we explore the involvement of the MNKs in brain-derived neurotrophic factor (BDNF)-stimulated protein synthesis in cortical
Sung-Gil Hong et al.
Environmental science & technology, 49(7), 4466-4472 (2015-03-31)
We developed a process for one-pot CO2 conversion and utilization based on simple conversion of CO2 to bicarbonate at ambient temperature with no energy input, by using the cross-linking-based composites of carboxylated polyaniline nanofibers (cPANFs) and carbonic anhydrase. Carbonic anhydrase
Akueni L Davelaar et al.
Scandinavian journal of gastroenterology, 50(3), 321-332 (2015-01-07)
Molecular processes underlying Barrett's malignant development are poorly understood. Matrix metalloproteases (MMPs) are enzymes involved in inflammation, tissue remodeling, and malignant development. Therefore, active MMPs may have a role in early metaplasia development and Barrett's esophagus' malignant progression. We desired
Douglas D Lemon et al.
FEBS letters, 589(10), 1080-1088 (2015-03-31)
PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors
K Madhumathi et al.
Drug delivery and translational research, 8(5), 1066-1077 (2018-05-03)
A dual local drug delivery system (DDS) composed of calcium phosphate bioceramic nanocarriers aimed at treating the antibacterial, anti-inflammatory, and bone-regenerative aspects of periodontitis has been developed. Calcium-deficient hydroxyapatite (CDHA, Ca/P = 1.61) and tricalcium phosphate (β-TCP) were prepared by microwave-accelerated wet
Mitsukazu Sakata et al.
Breeding science, 64(4), 309-320 (2015-04-29)
Hybrid incompatibility plays an important role in establishment of post-zygotic reproductive isolation. To unveil genetic basis of hybrid incompatibilities between diverged species of genus Oryza AA genome species, we conducted genetic dissection of hybrid sterility loci, S22(t), which had been
Ying Liu et al.
Biochimica et biophysica acta, 1848(1 Pt A), 67-75 (2014-10-07)
Molecular interactions between engineered nanomaterials (ENM) and biomembranes are not well understood. This study investigated the effects of particle size and surface functional group on polystyrene nanoparticles' (PNPs) potency for biomembrane disruption. Electrochemical impedance spectroscopy was used to measure changes
J M Moreno-Baquero et al.
Food chemistry, 138(1), 1-8 (2012-12-26)
This work studies the effect of packing cracked seasoned olives with NaCl, KCl, and CaCl(2) mixture brines on their mineral nutrients and sensory attributes, using RSM methodology. The Na, K, Ca, and residual natural Mn contents in flesh as well
Hyo Kyun Chung et al.
Liver international : official journal of the International Association for the Study of the Liver, 35(4), 1341-1353 (2014-12-03)
Nonalcoholic steatohepatitis (NASH) is associated with cirrhosis and hepatocellular carcinoma. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play key roles in the development of the disease. However, the therapeutic target of NASH has not been fully defined and
Els N Dumoulin et al.
Clinical chemistry and laboratory medicine, 53(1), 65-71 (2014-07-06)
Calprotectin is a 36 kDa calcium and zinc binding protein. An increased level of calprotectin points towards inflammatory bowel disease. However, the biomarker calprotectin shows 14 potential cleavages sites for trypsin. Next to trypsin, also the presence of its inhibitor
Mathew D Littlejohn et al.
Nature communications, 5, 5861-5861 (2014-12-19)
Lactation, hair development and homeothermy are characteristic evolutionary features that define mammals from other vertebrate species. Here we describe the discovery of two autosomal dominant mutations with antagonistic, pleiotropic effects on all three of these biological processes, mediated through the
Atsushi Kurata et al.
Marine biotechnology (New York, N.Y.), 17(3), 277-284 (2015-02-15)
A hyaluronate lyase (BniHL) was purified to homogeneity from a culture of a deep-sea Bacillus niacin strain JAM F8. The molecular mass of purified BniHL was approximately 120 kDa. The purified enzyme degraded hyaluronan as well as chondroitin sulfates A
Marie-Claire Janin-Bussat et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 981-982, 9-13 (2015-01-18)
Antibody-drug conjugates (ADCs) are becoming a major class of oncology therapeutics. Because ADCs combine the monoclonal antibody specificity with the high toxicity of a drug, they can selectively kill tumor cells while minimizing toxicity to normal cells. Most of the
Yan-Hua Bing et al.
Die Pharmazie, 70(2), 129-134 (2015-05-23)
Cerebellar Purkinje cells (PCs) respond to sensory stimulation via climbing fiber and mossy fiber-granule cell pathways, and generate motor-related outputs according to internal rules of integration and computation. However, the dynamic properties of sensory information processed by PC in mouse
Yong Wang et al.
Cell transplantation, 24(1), 25-36 (2013-09-28)
Diazoxide (DZ) is a pharmacological opener of ATP-sensitive K(+) channels that has been used for mimicking ischemic preconditioning and shows protection against ischemic damage. Here we investigated whether diazoxide supplementation to University of Wisconsin (UW) solution has cellular protection during
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