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Showing 31-60 of 580 results for "21049" within Papers
Atsushi Kurata et al.
Marine biotechnology (New York, N.Y.), 17(3), 277-284 (2015-02-15)
A hyaluronate lyase (BniHL) was purified to homogeneity from a culture of a deep-sea Bacillus niacin strain JAM F8. The molecular mass of purified BniHL was approximately 120 kDa. The purified enzyme degraded hyaluronan as well as chondroitin sulfates A
Young Mi Song et al.
Autophagy, 11(1), 46-59 (2014-12-09)
Metformin activates both PRKA and SIRT1. Furthermore, autophagy is induced by either the PRKA-MTOR-ULK1 or SIRT1-FOXO signaling pathways. We aimed to elucidate the mechanism by which metformin alleviates hepatosteatosis by examining the molecular interplay between SIRT1, PRKA, and autophagy. ob/ob
Agnieszka Bala et al.
Bioelectrochemistry (Amsterdam, Netherlands), 119, 189-195 (2017-10-22)
A novel electrochemical PNA-based biosensor for the determination of Hg
Tilen Koklic et al.
The Biochemical journal, 467(1), 37-46 (2015-01-13)
Exposure of phosphatidylserine (PS) molecules on activated platelet membrane surface is a crucial event in blood coagulation. Binding of PS to specific sites on factor Xa (fXa) and factor Va (fVa) promotes their assembly into a complex that enhances proteolysis
Akueni L Davelaar et al.
Scandinavian journal of gastroenterology, 50(3), 321-332 (2015-01-07)
Molecular processes underlying Barrett's malignant development are poorly understood. Matrix metalloproteases (MMPs) are enzymes involved in inflammation, tissue remodeling, and malignant development. Therefore, active MMPs may have a role in early metaplasia development and Barrett's esophagus' malignant progression. We desired
Douglas D Lemon et al.
FEBS letters, 589(10), 1080-1088 (2015-03-31)
PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors
Masoud M Ardestani et al.
Environmental pollution (Barking, Essex : 1987), 246, 19-25 (2018-12-12)
The aim of this study was to assess the effect of major cations (Ca2+, Mg2+, Na+, K+, and H+) on cadmium toxicity to the springtail Folsomia candida. Survival of the animals was determined after seven days exposure to different cadmium
Seyedeh-Maryam Hasheminya et al.
Food chemistry, 289, 443-452 (2019-04-09)
Kefiran-carboxymethyl cellulose biocomposite films incorporated with Satureja Khuzestanica essential oil were developed and characterized. Results indicated that increase in the concentration of the essential oil increased ultimate tensile strength and contact angle but decreased elongation at break, moisture content and
Stanley Ka-Lok Li et al.
Investigative ophthalmology & visual science, 56(2), 1396-1405 (2015-02-07)
Aqueous humor inflow falls 50% during sleeping hours without proportional fall in IOP, partly reflecting reduced outflow facility. The mechanisms underlying outflow facility cycling are unknown. One outflow facility regulator is matrix metalloproteinase (MMP) release from trabecular meshwork (TM) cells.
Maja Genheden et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(3), 972-984 (2015-01-23)
Although the MAP kinase-interacting kinases (MNKs) have been known for >15 years, their roles in the regulation of protein synthesis have remained obscure. Here, we explore the involvement of the MNKs in brain-derived neurotrophic factor (BDNF)-stimulated protein synthesis in cortical
Sung-Gil Hong et al.
Environmental science & technology, 49(7), 4466-4472 (2015-03-31)
We developed a process for one-pot CO2 conversion and utilization based on simple conversion of CO2 to bicarbonate at ambient temperature with no energy input, by using the cross-linking-based composites of carboxylated polyaniline nanofibers (cPANFs) and carbonic anhydrase. Carbonic anhydrase
Arnaud Paré et al.
ACS biomaterials science & engineering, 6(1), 553-563 (2020-03-12)
Finding alternative strategies for the regeneration of craniofacial bone defects (CSD), such as combining a synthetic ephemeral calcium phosphate (CaP) implant and/or active substances and cells, would contribute to solving this reconstructive roadblock. However, CaP's architectural features (i.e., architecture and
Clarissa Muere et al.
Respiratory physiology & neurobiology, 205, 7-15 (2014-09-30)
Reverse dialysis of the muscarinic receptor antagonist, atropine (ATR, 50 mM), into the pre-Bötzinger Complex region of the ventral respiratory column (VRC) of awake and sleeping goats increases breathing frequency and serotonin (5-HT), substance P (SP), glycine, and GABA concentrations
Jie Hong Hu et al.
Cardiovascular research, 105(3), 372-382 (2015-01-27)
Elevated activity of urokinase plasminogen activator (uPA) and MMPs in human arteries is associated with accelerated atherosclerosis, aneurysms, and plaque rupture. We used Apoe-null mice with macrophage-specific uPA overexpression (SR-uPA mice; a well-characterized model of protease-accelerated atherosclerosis) to investigate whether
Florence Anquetil et al.
Journal of immunology (Baltimore, Md. : 1950), 194(8), 3664-3674 (2015-03-15)
Rheumatoid factors (RF) and the disease-specific anti-citrullinated protein autoantibodies (ACPA) coexist in the joints of rheumatoid arthritis (RA) patients where they probably contribute to synovitis. We investigated the influence of IgM and IgA RF on the FcR- and complement-dependent effects
Chandrani Sarkar et al.
Carbohydrate polymers, 181, 710-718 (2017-12-20)
In this work, carbon dots conjugated carboxymethyl cellulose-hydroxyapatite nanocomposite has been synthesized by one-pot synthesis method and used for multiple applications like metal ion sensing, osteogenic activity, bio-imaging and drug carrier. The structure and morphology of the nanocomposite were systematically
A Moorthi et al.
Materials science & engineering. C, Materials for biological applications, 43, 458-464 (2014-09-02)
At nanoscale, bioglass ceramic (nBGC) particles containing calcium oxide (lime), silica and phosphorus pentoxide promote osteoblast proliferation. However, the role of varied amounts of calcium and silica present in nBGC particles on osteoblast proliferation is not yet completely known. Hence
Rong-Cing Huang et al.
ACS applied materials & interfaces, 6(24), 21780-21787 (2014-04-16)
In this study, we developed a label-free, ultrasensitive graphene oxide (GO)-based probe for the detection of oligonucleotides by laser desorption/ionization mass spectrometry (LDI-MS). On the basis of simple π-π stacking and electrostatic interactions between rhodamine 6G (R6G) and GO, we
Atsuo Kanno et al.
Nature communications, 6, 6119-6119 (2015-02-05)
Toll-like receptor 7 (TLR7) senses microbial-derived RNA but can also potentially respond to self-derived RNA. To prevent autoimmune responses, TLR7 is thought to localize in endolysosomes. Contrary to this view, we show here that TLR7 is present on the cell
Shima Ghanavati Nasab et al.
International journal of biological macromolecules, 124, 429-443 (2018-11-20)
A novel adsorbent of chitosan/nanodiopside nanocomposite (CS-NDIO) was synthesized as a green composite for the removal of crystal violet (CV) and characterized by techniques like XRD, FT-IR, BET, and FESEM analysis. The influence of parameters like molar ratios of CS
Mitsukazu Sakata et al.
Breeding science, 64(4), 309-320 (2015-04-29)
Hybrid incompatibility plays an important role in establishment of post-zygotic reproductive isolation. To unveil genetic basis of hybrid incompatibilities between diverged species of genus Oryza AA genome species, we conducted genetic dissection of hybrid sterility loci, S22(t), which had been
Gaber Hashem Gaber Ahmed et al.
Talanta, 132, 252-257 (2014-12-06)
Herein we describe an easy one step synthesis of carbon nanodots (C-dots) by thermal carbonization of 6-bromohexylboronic acid using two different amine compounds, polyethyleneglycol bis(3-aminopropyl (PEGA) and 1,2-aminopropane (DPA), at 180 °C in atmospheric oxygen. The as-synthesized C-dots were characterized
Xichan He et al.
International journal of biological macromolecules, 137, 45-53 (2019-06-21)
Inspired by the mechanism of bone formation, a porous collagen-carboxymethyl cellulose/hydroxyapatite (Col-CMC/HA) composite was designed and fabricated using a biomimetic template of Col and CMC protein-polysaccharide bi-molecules. The morphology, composition and physical properties of Col-CMC/HA composites were characterized systematically. It
Hengwen Yang et al.
Nature communications, 6, 5717-5717 (2015-01-08)
The conserved phosphatidylserine receptor (PSR) was first identified as a receptor for phosphatidylserine, an 'eat-me' signal exposed by apoptotic cells. However, several studies suggest that PSR may also act as an arginine demethylase, a lysyl hydroxylase, or an RNA-binding protein
Natalie C Schlegel et al.
Experimental dermatology, 24(1), 22-28 (2014-11-05)
Epithelial to mesenchymal transition (EMT) is a programme defined in epithelial cells and recognized as playing a critical role in cancer progression. Although melanoma is not a cancer of epithelial cells, hallmarks of EMT have been described to play a
Mais Al-Natsheh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 103-109 (2015-02-11)
A gas chromatography/mass spectrometric method was developed for the simultaneous determination of eight phthalic acid esters (PAEs) in toys and child care articles that are made of plasticized plastic. The novel method was used to determine the total concentration of
Grazia Accardo et al.
Materials (Basel, Switzerland), 12(5) (2019-03-02)
To be suitable as electrolytes in intermediate temperature solid oxide fuel cell (IT-SOFC), ceramic precursors have to be characterized by high sintering aptitude for producing fully densified products which are needed for this kind of application. Therefore, synthesis processes able
Anti-cyclic citrullinated peptide antibodies and paraoxonase-1 polymorphism in rheumatoid arthritis.
Hassan El-Banna et al.
BMC musculoskeletal disorders, 15, 379-379 (2014-11-20)
Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease, with a worldwide prevalence of 0.5% to 1%. Anti-cyclic citrullinated peptide antibody (anti-CCP-2 Ab) is a marker of choice for diagnosing early and late RA. Anti-oxidant enzymes activity decreases
Hsiao-Li Wu et al.
Fertility and sterility, 103(4), 1098-1106 (2015-02-17)
To determine whether berberine (BBR), a naturally occurring plant-derived alkaloid, inhibits the proliferation of human uterine leiomyoma (UtLM) cells. Laboratory research. Laboratory. UtLM and normal human uterine smooth muscle (UtSMC) cell lines. Treatment with [1] BBR (10, 20, and 50
Rodrigo D A M Alves et al.
BMC genomics, 15, 965-965 (2014-11-09)
Ectopic vascular calcifications represent a major clinical problem associated with cardiovascular disease and mortality. However, the mechanisms underlying pathological vascular calcifications are largely unknown hampering the development of therapies to tackle this life threatening medical condition. In order to gain
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