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Synthesis of new bergenin derivatives as potent inhibitors of inflammatory mediators NO and TNF-α.

Muhammad Raza Shah et al.

Bioorganic & medicinal chemistry letters, 22(8), 2744-2747 (2012-03-23)

Bergenin is an isocoumarin natural product which aides in fat loss, healthy weight maintenance, enhancing the lipolytic effects of norepinephrine, inhibiting the formation of interleukin 1α and cyclooxygenases-2. Here we describe the anti-inflammatory activity of new bergenin derivatives 1-15 in

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