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Showing 1-30 of 232 results for "21223" within Papers
Francisco Miguel Cardoso et al.
Journal of virology, 88(15), 8278-8296 (2014-05-16)
Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NA-specific single-domain antibodies (N1-VHHm) and evaluated their in vitro and in vivo antiviral potential. Two of them inhibited the NA activity and
Takamasa Shimizu et al.
Cryobiology, 66(3), 326-332 (2013-04-09)
Cryopreservation of tissue engineered bone (TEB), whilst maintaining its osteogenic ability, is imperative for large-scale clinical application. We previously reported a novel cell transplantation method, in which bone-marrow-derived mesenchymal stem cells (BMSCs) were cultured to confluence and differentiated down the
Constantin Landes et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(7), 1328-1338 (2014-04-08)
To evaluate the internal fixation of malar and midfacial fractures, long-term results, and biocompatibility of osteoconductive internal fixation devices composed of a forged composite of unsintered hydroxyapatite and poly-L-lactide (F-u-HA/PLLA). From January 2006 to June 2010, 29 patients (24 males
Shin-Woo Ha et al.
Biomaterials, 65, 32-42 (2015-07-05)
Hydroxyapatite (HA) is the primary structural component of the skeleton and dentition. Under biological conditions, HA does not occur spontaneously and therefore must be actively synthesized by mineralizing cells such as osteoblasts. The mechanism(s) by which HA is actively synthesized
Cosimo Loperfido et al.
The Journal of oral implantology, 40(6), 707-713 (2013-04-12)
A 71-year-old patient was successfully rehabilitated by means of a 3D model-derived, hydroxyapatite-coated titanium subperiosteal mandibular implant. The implant was specifically designed to allow bone augmentation. The deficient bone was simultaneously grafted with mineralized bone allograft and recombinant bone morphogenetic
Min-Soo Kim et al.
Journal of periodontal & implant science, 43(1), 18-23 (2013-03-20)
The purpose of this study was to evaluate the osseointegration of calcium phosphate (CaP)-coated implants by ion beam assisted deposition with a lack of primary stability. A total of 20 CaP-coated implants were bilaterally placed in the mandible of five
Senthilguru Kulanthaivel et al.
Materials science & engineering. C, Materials for biological applications, 58, 648-658 (2015-10-20)
The present study delineates the synthesis and characterization of cobalt doped proangiogenic-osteogenic hydroxyapatite. Hydroxyapatite samples, doped with varying concentrations of bivalent cobalt (Co(2+)) were prepared by the ammoniacal precipitation method and the extent of doping was measured by ICP-OES. The
Marwa Madi et al.
The Journal of oral implantology, 40(6), 661-669 (2013-01-08)
In this study, hydroxyapatite coated vs uncoated implants were used to evaluate the type and dimensions of bone defects after progressive peri-implantitis in dogs. Thirty-two dental implants with 4 different surfaces-machined (M), sandblasted acid-etched (SA), 1-μm thin sputter hydroxyapatite (HA)-coated
Liming Jiang et al.
Journal of biomedical nanotechnology, 9(11), 1921-1928 (2013-09-26)
Simvastatin is considered as a stimulator for bone formation. However, the half-life for simvastatin is generally 2 hours, which means, it is difficult to maintain biologically active simvastatin in vivo. To overcome this limitation, we created a system to slowly
Yang Lei et al.
Experimental cell research, 323(1), 198-208 (2014-01-23)
Vascular calcification can be categorized into two different types. Intimal calcification related to atherosclerosis and elastin-specific medial arterial calcification (MAC). Osteoblast-like differentiation of vascular smooth muscle cells (VSMCs) has been shown in both types; however, how this relates to initiation
Naomi M de Almeida et al.
Journal of bacteriology, 197(14), 2432-2441 (2015-05-13)
Anaerobic ammonium-oxidizing (anammox) bacteria oxidize ammonium with nitrite as the terminal electron acceptor to form dinitrogen gas in the absence of oxygen. Anammox bacteria have a compartmentalized cell plan with a central membrane-bound "prokaryotic organelle" called the anammoxosome. The anammoxosome
José Luis Calvo-Guirado et al.
Clinical oral implants research, 26(8), 891-897 (2014-05-28)
The aim of this study was to assess the bone regeneration of critical size defects in rabbit calvarias filled with β-TCP doped with silicon. Twenty-one New Zealand rabbits were used in this study. Two critical size defects were created in
Lenka Novotna et al.
Materials science & engineering. C, Materials for biological applications, 95, 363-370 (2018-12-24)
In this study, a reproducible method of fabricating hierarchically 3D porous scaffolds with high porosity and pore interconnectivity is reported. The method is based on in-situ foaming of a dispersion of diisocyanate, polyol, water and hydroxyapatite (HA) to form a
Metallosis and elevated serum levels of tantalum following failed revision hip arthroplasty--a case report.
George C Babis et al.
Acta orthopaedica, 85(6), 677-680 (2014-08-21)
Hamid Esfahani et al.
Journal of colloid and interface science, 443, 143-152 (2014-12-30)
Surface modification of electrospun polymeric membrane surfaces is a critical step towards the separation process including protein adsorption. In this study, the electrospun Nylon fibers was incorporated with positively charged zinc doped hydroxyapatite (HAp) nanoparticles to study the adsorption of
G He et al.
Cell proliferation, 47(3), 258-266 (2014-04-18)
To improve efficacy of current titanium and its alloys, in bioactivity and speed of osseointegration, of orthopaedic implants. A novel triple-layered functional graded coating, consisting of a porous hydroxyapatite (HA) outermost layer, fluoro-HA (FHA) intermediate layer and titanium oxide (TiO2
Bernhard Gasselhuber et al.
Biochemistry, 54(35), 5425-5438 (2015-08-21)
Recently, it was demonstrated that bifunctional catalase-peroxidases (KatGs) are found not only in archaea and bacteria but also in lower eukaryotes. Structural studies and preliminary biochemical data of the secreted KatG from the rice pathogen Magnaporthe grisea (MagKatG2) suggested both
Georgios N Belibasakis et al.
Virulence, 6(7), 704-709 (2015-08-26)
Periodontitis is an infectious inflammatory disease that destroys the tooth-supporting tissues. It is caused by the formation of subgingival biofilms on the surface of the tooth. Characteristic bacteria associated with subgingival biofilms are the Gram-negative anaerobes Porphyromonas gingivalis, Tannerella forsythia
J-A Epinette et al.
The bone & joint journal, 95-B(12), 1610-1616 (2013-12-03)
We report a multicentre prospective consecutive study assessing the long-term outcome of the proximally hydroxyapatite (HA)-coated ABG II monobloc femoral component in a series of 1148 hips in 1053 patients with a mean age at surgery of 64.77 years (22
Paul D Fisher et al.
Journal of biomedical materials research. Part A, 103(7), 2365-2373 (2014-11-27)
In situ forming poly(lactic-co-glycolic acid) (PLGA) implants have not been strongly considered for bone applications because of their poor mechanical properties. Here, in situ forming scaffolds containing hydroxyapatite micro- and nanoparticles were characterized to determine their mechanical properties, injectability, and
Rene Olivares-Navarrete et al.
Spine, 40(6), 399-404 (2015-01-15)
An in vitro study examining factors produced by human mesenchymal stem cells on spine implant materials. The aim of this study was to examine whether the inflammatory microenvironment generated by cells on titanium-aluminum-vanadium (Ti-alloy, TiAlV) surfaces is affected by surface
Sunil Kumar et al.
Prostaglandins & other lipid mediators, 118-119, 28-33 (2015-05-13)
The objective of the study was to investigate the role of prostaglandin D2 during pregnancy and its mediator Lipocalin-type prostaglandin D2 synthase (L-PGDS) as a predictor of preterm birth (PTB). Transgenic L-PGDS (+/+), L-PGDS (-/-) and C57BL/6 control pregnant mice
Ui-Won Jung et al.
Journal of periodontal & implant science, 43(2), 64-71 (2013-05-17)
The objective of this study was to elucidate the role of collagen membranes (CMs) when used in conjunction with bovine hydroxyapatite particles incorporated with collagen matrix (BHC) for lateral onlay grafts in dogs. The first, second, and third premolars in
K R Remya et al.
Journal of biomedical nanotechnology, 9(9), 1483-1494 (2013-08-29)
The present work is a comparative evaluation of physical and biological properties of electrospun biodegradable fibrous scaffolds based on polycaprolactone (PCL) and its blend with polycaprolactone-polyethyleneglycol-polycaprolactone (CEC) with and without nanohydroxyapatite (nHAP) particles. The fiber morphology, porosity, surface wettability, and
Jean D A Carruthers et al.
Plastic and reconstructive surgery, 134(6), 1197-1201 (2014-11-22)
Vascular occlusion causing blindness is a rare yet greatly feared complication of the use of facial aesthetic fillers. The authors performed a review of the aesthetic literature to ascertain the reported cases of blindness and the literature reporting variations in
Lu-Ning Wang et al.
Journal of nanoscience and nanotechnology, 13(8), 5316-5326 (2013-07-26)
Electrochemically anodized TiO2 nanotubular arrays can provide large surface areas for biological species attachment. In order to further enhance the biocompatibility of Ti medical implants, we deposited a pre-synthesized hydroxyapatite inside and on the nanotubular arrays, and examined the biocompatibility
Ming Pei et al.
Bone, 78, 1-10 (2015-05-06)
Repairing large bone defects presents a significant challenge, especially in those people who have a limited regenerative capacity such as in osteoporotic (OP) patients. The aim of this study was to compare adipose stem cells (ASCs) from both normal (NORM)
Zhao Shifang et al.
Journal of biomedical nanotechnology, 10(7), 1313-1319 (2014-05-09)
The aim of this study was to deposit simvastatin-hydroxyapatite (sim-HA) coatings on titanium surfaces by an electrochemical process and evaluate osteoprogenitor cell responses to sim-HA-coated surfaces. Simvastatin was prepared onto titanium surfaces with varying concentration (10(-7), 10(-6), 10(-5) and 10(-4)
Cheng-Yeu Wu et al.
The Journal of biological chemistry, 288(42), 30571-30584 (2013-08-31)
Recent studies indicate that membrane vesicles (MVs) secreted by various cells are associated with human diseases, including arthritis, atherosclerosis, cancer, and chronic kidney disease. The possibility that MVs may induce the formation of mineralo-organic nanoparticles (NPs) and ectopic calcification has
Marc A Fernandez-Yague et al.
Advanced drug delivery reviews, 84, 1-29 (2014-09-23)
The development of responsive biomaterials capable of demonstrating modulated function in response to dynamic physiological and mechanical changes in vivo remains an important challenge in bone tissue engineering. To achieve long-term repair and good clinical outcomes, biologically responsive approaches that
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