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Showing 1-30 of 232 results for "21223" within Papers
A I Espirito Santo et al.
Biochemical and biophysical research communications, 464(4), 1145-1150 (2015-07-26)
The treatment of autoimmune disorders has been revolutionised by the introduction of biologics such as anti-tumour necrosis factor (anti-TNF). Although in rheumatoid arthritis patients a bone sparing effect of anti-TNF has been shown, the mechanism is not fully understood. Anti-TNF
Melanie Jean Coathup et al.
The Journal of bone and joint surgery. American volume, 95(17), 1569-1575 (2013-09-06)
The objective of this study was to examine the degree of osteointegration into a hydroxyapatite-coated collar and relate this finding to aseptic loosening in patients with a distal femoral replacement used to treat primary bone cancer. Our hypothesis was that
A Doustgani et al.
Journal of nanoscience and nanotechnology, 13(7), 4708-4714 (2013-08-02)
Electrospinning is a process that produces continuous polymer fibers in the sub-micron range through the action of an external electric field imposed on a polymer solution or melt. In this study the effects of process parameters on the mean diameter
Giulia Pavani et al.
Blood, 124(7), 1157-1165 (2014-06-25)
Recombinant activated human factor VII (rhFVIIa) is an established hemostatic agent in hemophilia, but its mechanism of action remains unclear. Although tissue factor (TF) is its natural receptor, rhFVIIa also interacts with the endothelial protein C receptor (EPCR) through its
Julien Ramier et al.
Journal of materials science. Materials in medicine, 25(6), 1563-1575 (2014-03-04)
Electrospinning coupled with electrospraying provides a straightforward and robust route toward promising electrospun biocomposite scaffolds for bone tissue engineering. In this comparative investigation, four types of poly(3-hydroxybutyrate) (PHB)-based nanofibrous scaffolds were produced by electrospinning a PHB solution, a PHB/gelatin (GEL)
M S Laranjeira et al.
Journal of biomedical nanotechnology, 9(9), 1594-1606 (2013-08-29)
Recent studies have shown that hydroxyapatite (HA) nanocrystalline have better functional properties that are important to create suitable local conditions for bone formation, when implanted in an osseous environment. Bone formation depends on several complex processes, including a tight communication
David Pastorino et al.
Acta biomaterialia, 28, 205-214 (2015-09-20)
Characterization of the intricate pore structure of calcium phosphate cements is a key step to successfully link the structural properties of these synthetic bone grafts with their most relevant properties, such as in vitro or in vivo behaviour, drug loading
Anderson O Lobo et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 4305-4312 (2013-08-06)
Large amounts of nanohydroxyapatite (nHAp)-multiwall carbon nanotube (MWCNT) nanocomposites are produced by two different aqueous precipitation methods. The ultrasonic irradiation (UI) and slow-drip addition under continuous magnetic stirring (DMS) methods were used to investigate the precipitation of nHAp acicular crystals.
Yuichiro Ohtsuka et al.
Nihon Jibiinkoka Gakkai kaiho, 116(11), 1200-1207 (2014-01-09)
Calcific retropharyngeal tendinitis/retropharyngeal calcific tendinitis is an inflammation of the longus colli muscle caused by calcium hydroxyapatite crystal depositon in the longus colli muscle tendon. The three major symptoms are neck pain, limitations of neck movement, and swallowing pain. We
Lyndon F Charles et al.
Experimental gerontology, 64, 62-69 (2015-02-15)
There is an age-associated reduction in the bone healing activity of bone morphogenetic protein-2 (BMP-2) that is currently addressed by administering higher doses of BMP-2 in elderly patients. The unwanted medical complications from high dose BMP-2 motivated this investigation to
Priscila Tomie Leme Ike et al.
SpringerPlus, 4, 654-654 (2015-11-07)
In this work we have identified, using mass spectrometry, two laccases produced by Leucoagaricus gongylophorus. One of them, Lac1Lg, was isolated, purified and characterized. Lac1Lg, a monomeric enzyme, was studied using ABTS and syringaldazine substrates. Lac1Lg presented kcat/Km almost threefold
Niladri Nath Panda et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 103(5), 971-982 (2014-09-02)
This study evaluated the mechanical properties and osteogenic potential of a silk fibroin scaffold prepared from a 70:30 blend of Eri (Philosamia ricini) and Tasar (Antheraea mylitta) silk, respectively (ET scaffolds). An electrospinning process was used to prepare uniformly blended
Sathiyamoorthy Ezhaveni et al.
Journal of nanoscience and nanotechnology, 13(3), 1631-1638 (2013-06-13)
Nano-hydroxyapatite was synthesized by means of the hydrothermal treatment. The effects of nano-hydroxyapatite material on the behaviour of G2 liver cancer cells were explored. About 50% of cell viability was lost in nHAp material treated cells at 200 degrees C
Nathan H Dormer et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 4343-4351 (2013-08-06)
Macromolecule release from poly(d,l-lactide-co-glycolide) (PLGA) microspheres has been well-characterized, and is a popular approach for delivering bioactive signals from tissue-engineered scaffolds. However, the effect of some processing solvents, sterilization, and mineral incorporation (when used in concert) on long-term release and
Placement of a modified subperiosteal implant: a clinical solution to help those with no bone.
Ara Nazarian
Dentistry today, 33(7), 134-134 (2014-08-15)
Betul Kul Babur et al.
Cell and tissue research, 361(3), 755-768 (2015-05-01)
Engineered biphasic osteochondral tissues may have utility in cartilage defect repair. As bone-marrow-derived mesenchymal stem/stromal cells (MSC) have the capacity to make both bone-like and cartilage-like tissues, they are an ideal cell population for use in the manufacture of osteochondral
Miklós Bély et al.
Orvosi hetilap, 154(23), 908-913 (2013-06-04)
Mönckeberg's sclerosis is a special form of arteriosclerosis characterized by calcification and ossification of the media of medium size arteries mainly of lower extremities. The aim of the authors was to examine medium size arteries with Mönckeberg's sclerosis in 22
Yoshikuni Goto et al.
Journal of biochemistry, 157(6), 439-449 (2015-01-13)
In this study, we examined the role of aminopeptidases with reference to endoplasmic reticulum aminopeptidase 1 (ERAP1) in nitric oxide (NO) synthesis employing murine macrophage cell line RAW264.7 cells activated by lipopolysaccharide (LPS) and interferon (IFN)-γ and LPS-activated peritoneal macrophages
Craig J van Dolleweerd et al.
The Journal of infectious diseases, 210(2), 200-208 (2014-02-11)
Rabies post-exposure prophylaxis (PEP) currently comprises administration of rabies vaccine together with rabies immunoglobulin (RIG) of either equine or human origin. In the developing world, RIG preparations are expensive, often in short supply, and of variable efficacy. Therefore, we are
Xi Yang et al.
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 27(9), 1085-1089 (2013-11-28)
To assess the mid-term effectiveness of anterior decompression and fusion with nanohydroxyapatite/polyamide 66 (n-HA/PA66) cage in treatment of cervical spondylotic myelopathy. A retrospective study was made on 48 patients with cervical spondylotic myelopathy who underwent anterior decompression and fusion with
Hyun Wook Huh et al.
Carbohydrate polymers, 126, 130-140 (2015-05-03)
A biomineralized hydrogel system containing hyaluronic acid (HA) and poloxamer composed of a poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) (PEO-PPO-PEO) block copolymer was developed as a biomimetic thermo-responsive injectable hydrogel system for bone regeneration. Using HA and poloxamer macromers with polymerizable residues
Aysel Koç et al.
Journal of biomaterials applications, 29(5), 748-760 (2014-07-27)
Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an angiogenic gene-activated scaffold. In the current study, porous chitosan/hydroxyapatite (C/HA)
Jie Deng et al.
Oral oncology, 51(9), 824-831 (2015-07-23)
Concurrent chemoradiation (CCR) therapy is a standard treatment for patients with locally advanced head and neck cancer (HNC). It is well documented that CCR causes profound acute and late toxicities. Xerostomia (the symptom of dry mouth) and hyposalivation (decreased salivary
Takaya Kurokawa et al.
Drug metabolism and disposition: the biological fate of chemicals, 43(8), 1218-1225 (2015-05-17)
Diltiazem, a calcium channel blocker, is mainly metabolized via demethylation or deacetylation in humans. Diltiazem demethylation is catalyzed by cytochrome P450 2D6 and 3A4. Although it was previously reported that the area under the curve ratio of deacetyldiltiazem to diltiazem
Shih-Yeh Lin et al.
Biotechnology and bioengineering, 112(10), 2005-2015 (2015-05-23)
Enterovirus 71 (EV71) is responsible for the outbreaks of hand-foot-and-mouth disease in the Asia-Pacific region. To produce the virus-like particle (VLP) vaccine, we previously constructed recombinant baculoviruses to co-express EV71 P1 polypeptide and 3CD protease using the Bac-to-Bac(®) vector system.
Shoji Ohgami et al.
Plant physiology, 168(2), 464-477 (2015-04-30)
Tea plants (Camellia sinensis) store volatile organic compounds (VOCs; monoterpene, aromatic, and aliphatic alcohols) in the leaves in the form of water-soluble diglycosides, primarily as β-primeverosides (6-O-β-D-xylopyranosyl-β-D-glucopyranosides). These VOCs play a critical role in plant defenses and tea aroma quality
Mark D Wilkie et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 151(6), 1014-1019 (2014-09-24)
Recently, a novel hydroxyapatite-coated concave bone-anchored hearing device abutment was introduced, the first designed specifically to improve outcomes in soft-tissue preservation osseointegrated hearing implant surgery. We sought to evaluate our early experience with this abutment. A single-center case series with
The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals
Royal Society of Chemistry null
Hideyuki Arimitsu et al.
Microbiology and immunology, 59(2), 71-81 (2014-12-19)
Shiga toxin 2 (Stx2)-specific mAb-producing hybridoma clones were generated from mice. Because mice tend to produce small amounts of B subunit (Stx2B)-specific antibodies at the polyclonal antibody level after immunization via the parenteral route, mice were immunized intranasally with Stx2
D Vukosavljevic et al.
Journal of dental research, 93(5), 514-519 (2014-03-05)
The acquired enamel pellicle (AEP) is important for minimizing the abrasion caused by parafunctional conditions as they occur, for instance, during bruxism. It is a remarkable feature of the AEP that a protein/peptide film can provide enough protection in normofunction
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