221-222-6

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Showing 1-8 of 8 results for "221-222-6" within Papers

The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway.

Hsin-Ching Sung et al.

Phytomedicine : international journal of phytotherapy and phytopharmacology, 42, 90-99 (2018-04-16)

The extracts from wild bitter gourd fruit (WBGE) were reported to possess numerous pharmacological activities. However, the anti-inflammatory effects of WBGE on human lung epithelial cells and the underlying mechanisms have not been determined. To evaluate the molecular basis of

MicroRNA profiling reveals aberrant microRNA expression in adult ETP-ALL and functional studies implicate a role for miR-222 in acute leukemia.

Ebru Coskun et al.

Leukemia research, 37(6), 647-656 (2013-03-26)

Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-risk subgroup in acute T-cell lymphoblastic leukemia (T-ALL). To investigate the immature and myeloid nature of ETP-ALL we examined global microRNA (miRNA) expression in adult ETP-ALL. miRNA profiling of

A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility.

Martijn Kedde et al.

Nature cell biology, 12(10), 1014-1020 (2010-09-08)

Key regulators of 3' untranslated regions (3' UTRs) are microRNAs and RNA-binding proteins (RBPs). The p27 tumour suppressor is highly expressed in quiescent cells, and its downregulation is required for cell cycle entry after growth factor stimulation. Intriguingly, p27 accumulates

Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4.

Satoshi Yamaguchi et al.

Frontiers in endocrinology, 12, 750261-750261 (2022-01-21)

MicroRNAs expressed in adipocytes are involved in transcriptional regulation of target mRNAs in obesity, but miRNAs critically involved in this process is not well characterized. Here, we identified upregulation of miR-221-3p and miR-222-3p in the white adipose tissues in C57BL/6

Determination of sodium metabisulfite in parenteral formulations by HPIC with suppressed conductivity detection.

Marzena Podolska et al.

Acta poloniae pharmaceutica, 68(5), 637-644 (2011-09-21)

Sulfurous compounds: sodium sulfite Na2SO3 (E 221), sodium bisulfite NaHSO, (E 222), and sodium metabisulfite Na2S2O5 (E 223) are largely used as antioxidants in many pharmaceutical formulations. A method for determination of sodium metabisulfite in parenteral formulations containing tartrate ions

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients.

Radek Lakomy et al.

Cancer science, 102(12), 2186-2190 (2011-09-08)

Glioblastoma multiforme (GBM) is the most frequently occurring primary malignant brain tumor; patients with GBM often have a very poor prognosis and differing responses to treatment. Therefore, it is very important to find new biomarkers that can predict clinical outcomes

MiR-score: a novel 6-microRNA signature that predicts survival outcomes in patients with malignant pleural mesothelioma.

Michaela B Kirschner et al.

Molecular oncology, 9(3), 715-726 (2014-12-17)

Prognosis of malignant pleural mesothelioma (MPM) is poor, and predicting the outcomes of treatment is difficult. Here we investigate the potential of microRNA expression to estimate prognosis of MPM patients. Candidate microRNAs from microarray profiling of tumor samples from 8

Stem cell-derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy-In a model of human-induced pluripotent stem cell-derived cardiomyocytes.

Alina Constantin et al.

Frontiers in pharmacology, 13, 1003684-1003684 (2022-10-28)

Cardiac pathological hypertrophy is the major risk factor that usually progresses to heart failure. We hypothesized that extracellular vesicles (EVs), known to act as important mediators in regulating physiological and pathological functions, could have the potential to reduce the cardiac

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