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Showing 1-30 of 57 results for "267317" within Papers
Pedro I da S Maia et al.
Dalton transactions (Cambridge, England : 2003), 42(14), 5111-5121 (2013-02-13)
Rhenium(V) complexes containing tridentate thiosemicarbazones/thiosemicarbazides (H2L1) derived from N-[N′,N′-dialkylamino(thiocarbonyl)]benzimidoyl chlorides with 4,4-dialkylthiosemicarbazides have been synthesized by ligand-exchange reactions starting from [ReOCl(L1)]. The chlorido ligand of [ReOCl(L1)] (4) is readily replaced and reactions with ammonium thiocyanate or potassium cyanide give [ReO(NCS)(L1)]
Ung Gi Hong et al.
Journal of nanoscience and nanotechnology, 13(11), 7448-7453 (2013-11-20)
Copper-containing mesoporous carbon (Cu-MC) was prepared by a single-step surfactant-templating method. For comparison, copper-impregnated mesoporous carbon (Cu/MC) was also prepared by a surfactant-templating method and a subsequent impregnation method. Rhenium catalysts supported on copper-containing mesoporous carbon and copper-impregnated mesoporous carbon
Thomas R Hayes et al.
Inorganic chemistry, 52(6), 3259-3267 (2013-03-01)
Click reactions offer a rapid technique to covalently assemble two molecules. In radiopharmaceutical construction, these reactions can be utilized to combine a radioactive metal complex with a biological targeting molecule to yield a potent tool for imaging or therapy applications.
Peter Wolohan et al.
Steroids, 72(3), 247-260 (2007-02-07)
OPLS all atom force field parameters were developed in order to model a diverse set of novel rhenium based estrogen receptor ligands whose relative binding affinities (RBA) to the estrogen receptor alpha isoform (ERalpha) with respect to 17beta-estradiol were available.
R Klett et al.
Rheumatology (Oxford, England), 46(10), 1531-1537 (2007-06-29)
Hypertrophy and inflammation of the synovium with various underlying pathologies - such as rheumatoid arthritis, osteoarthritis, haemophilia and spondyloarthropathy - can be treated successfully by radiosynoviorthesis (RSO). For medium-sized joints (shoulder, elbow, wrist, hip and ankle), the radionuclide of choice
Sarah Theiner et al.
Metallomics : integrated biometal science, 7(8), 1256-1264 (2015-04-10)
The selection of drug candidates for entering clinical development relies on in vivo testing in (solid) tumor animal models. However, the heterogeneity of tumor tissue (e.g. in terms of drug uptake or tissue composition) is rarely considered when testing novel
A T Porter et al.
Current opinion in oncology, 6(6), 607-610 (1994-11-01)
New advances in systemic radionuclide therapy have increased the number of treatment options available for patients with painful osseous metastases. This form of therapy has three major appeals: 1) it addresses all sites of involvement; 2) selective absorption into bone
Guo-Cang Wang et al.
Inorganic chemistry, 52(5), 2556-2563 (2013-02-15)
Heterometallic cerium(IV) perrhenate, permanganate, and molybdate complexes containing the imidodiphosphinate ligand [N(i-Pr2PO)2](-) have been synthesized, and their reactivity was investigated. Treatment of Ce[N(i-Pr2PO)2]3Cl (1) with AgMO4 (M = Re, Mn) afforded Ce[N(i-Pr2PO)2]3(ReO4) (2) or Ce2[N(i-Pr2PO)2]6(MnO4)2 (3). In the solid state
Radiolabeling of monoclonal antibodies and fragments with technetium and rhenium.
G L Griffiths et al.
Bioconjugate chemistry, 3(2), 91-99 (1992-03-01)
Malcolm Frier
Mini reviews in medicinal chemistry, 4(1), 61-68 (2004-02-03)
The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular
Philippe Collery et al.
Anticancer research, 34(4), 1679-1689 (2014-04-03)
We proposed a new water-soluble rhenium diseleno-ether compound (with one atom of Re and two atoms of Se) and investigated the uptake of Re into the nucleus of malignant cells in culture exposed to the compound for 48 h and
Jinhe Pan et al.
Bioorganic & medicinal chemistry letters, 23(6), 1720-1726 (2013-02-16)
To continue our efforts toward the development of (99m)Tc PiB analogs, we have synthesized 24 neutral and lipophilic Re (as a surrogate of (99m)Tc) 2-arylbenzothiazoles, and explored their structure-activity relationship for binding to Aβ1-40 fibrils. These Re complexes were designed
Jonathan M Smieja et al.
Inorganic chemistry, 52(5), 2484-2491 (2013-02-20)
Electrocatalytic properties, X-ray crystallographic studies, and infrared spectroelectrochemistry (IR-SEC) of Mn(bpy-tBu)(CO)3Br and [Mn(bpy-tBu)(CO)3(MeCN)](OTf) are reported. Addition of Brönsted acids to CO2-saturated solutions of these Mn complexes and subsequent reduction of the complexes lead to the stable and efficient production of
Christiane A Kluba et al.
Molecules (Basel, Switzerland), 18(3), 3206-3226 (2013-03-14)
The Click-to-Chelate approach is a highly efficient strategy for the radiolabeling of molecules of medicinal interest with technetium and rhenium-tricarbonyl cores. Reaction of azide-functionalized molecules with alkyne prochelators by the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC; click reaction) enables the simultaneous synthesis
M R A Pillai et al.
Current radiopharmaceuticals, 5(3), 228-243 (2012-05-31)
Rhenium-188 is one of the most readily available generator derived and useful radionuclides for therapy emitting β(-) particles (2.12 MeV, 71.1% and 1.965 MeV, 25.6%) and imageable gammas (155 keV, 15.1%). The (188)W/(188)Re generator is an ideal source for the
B Lambert et al.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 53(3), 305-310 (2009-06-13)
Rhenium-188 (188Re) is a high energy beta-emitter with a physical half life of 17 hours. Various 188Re based radiopharmaceuticals were developed to treat liver malignancies. The vast majority of studies focus on patients suffering from hepatocellular carcinoma (HCC). Most radiopharmaceuticals
Ume-Kalsoom Dar et al.
Pakistan journal of pharmaceutical sciences, 26(2), 367-373 (2013-03-05)
In this study, rhenium sulfide colloidal nanoparticles were developed as radiopharmaceutical for sentinel lymph node detection. We directly used rhenium sulfide as a starting material for the preparation of colloidal nanoparticles. UV-visible spectrophotometry was used for characterization of in house
Theshini Perera et al.
Inorganic chemistry, 52(5), 2412-2421 (2013-02-21)
We demonstrate that a tertiary sulfonamide group, N(SO2R)R'2, can rehybridize to form a M-N bond of normal length even when the group is in a linear tridentate ligand, such as in the new tridentate N(SO2R)dpa ligands derived from di-(2-picolyl)amine (N(H)dpa).
Huahui Zeng et al.
Dalton transactions (Cambridge, England : 2003), 42(8), 2894-2901 (2013-01-17)
[(99m)Tc(CO)(3)](+)-6-[N-(2-dipicolyl)amino]hexanoic acid (1a) and [(99m)Tc(CO)(3)](+)-11-[N-(2-dipicolyl)amino]undecanoic acid (1b) were prepared by incorporating [(99m)Tc-(CO)(3)](+) into 6-[N-(2-dipicolyl)amino]hexanoic acid and 11-[N-(2-dipicolyl)amino]undecanoic acid, respectively. The overall radiochemical yield of 1a and 1b was from 79.7% to 91.3% and radiochemical purity after HPLC purification was more
Ties J Korstanje et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(39), 13224-13234 (2013-08-16)
Rhenium-based complexes are powerful catalysts for the dehydration of various alcohols to the corresponding olefins. Here, we report on both experimental and theoretical (DFT) studies into the mechanism of the rhenium-catalyzed dehydration of alcohols to olefins in general, and the
Raphael Horvath et al.
Inorganic chemistry, 52(3), 1304-1317 (2013-01-15)
Transition-metal complexes of the types [Re(CO)(3)Cl(NN)], [Re(CO)(3)py(NN)](+), and [Cu(PPh(3))(2)(NN)](+), where NN = 4,4'-bis(5-phenyl-1,3,4-oxadiazol-2-yl)-2,2'-bipyridine (OX) and 4,4'-bis(N,N-diphenyl-4-[ethen-1-yl]-aniline)-2,2'-bipyridine (DPA), have been synthesized and characterized. Crystal structures for [Re(CO)(3)Cl(DPA)] and [Cu(PPh(3))(2)(OX)]BF(4) are presented. The crystal structure of the rhenium complex shows a trans
Titel Jurca et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(13), 4278-4286 (2013-02-02)
The development of rhenium(I) chemistry has been restricted by the limited structural and electronic variability of the common pseudo-octahedral products fac-[ReX(CO)3L2] (L2 = α-diimine). We address this constraint by first preparing the bidentate bis(imino)pyridine complexes [(2,6-{2,6-Me2C6H3N=CPh}2C5H3N)Re(CO)3X] (X = Cl 2
N Iznaga-Escobar
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 54(3), 399-406 (2001-02-24)
188Re is one of the radioisotopes expected to emerge as useful for therapy. Development of new radiopharmaceuticals based on 188Re depends on the radiolabeling methods used, which would give stable complexes having predefined radiochemical properties and in vitro and in
Baha Zengel et al.
Tumori, 99(2), 149-153 (2013-06-12)
Sentinel lymph node biopsy has been accepted as a standard procedure for early stage breast cancer. In this retrospective analysis, the results obtained with different methodological approaches using radiocolloid with or without blue dye were examined. A total of 158
Mark Bartholomä et al.
Chemical communications (Cambridge, England), (5)(5), 493-512 (2009-03-14)
Radiolabeled biomolecules can be used to visualize a variety of diseases through interaction with specific cell receptors. A key step is the introduction of a molecular entity that allows facile labeling with the medically useful radionuclide (99m)Tc without significant alteration
Michael G Haase et al.
International journal of radiation biology, 89(10), 863-869 (2013-04-13)
The objective of this study was to determine the dose-effect correlation of pneumopathy after application of Rhenium-188 microspheres (Re-188 MS) in an animal model using histological changes as an end-point. Wistar rats received an intravenous injection of Re-188 MS yielding
Wilber Quispe-Tintaya et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(21), 8668-8673 (2013-04-24)
No significant improvement in therapy of pancreatic cancer has been reported over the last 25 y, underscoring the urgent need for new alternative therapies. Here, we coupled a radioisotope, (188)Rhenium, to an attenuated (at) live Listeria monocytogenes (Listeria(at)) using Listeria-binding
Daniel Przyrembel et al.
Journal of physics. Condensed matter : an Institute of Physics journal, 25(9), 095009-095009 (2013-02-05)
We have studied the adsorption of copper on the clean Re(101[overline]0) surface between 300 and 900 K by means of low- and medium-energy electron diffraction (LEED and MEED) and temperature-programmed thermal desorption (TPD). The persistence of a (1 × 1)
F M van der Zant et al.
Clinical and experimental rheumatology, 27(1), 130-139 (2009-03-31)
To perform a systemic review and meta-analysis on the effectiveness of radiosynoviorthesis (RSO). A search of medical databases was conducted. Criteria for inclusion: articles in English, minimum follow-up of 6 months, specification of joint disease, reported outcome of at least
Daisuke Suzuki et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 96, 52-56 (2014-12-06)
Uranium and plutonium isotope ratios in individual uranium-plutonium (U-Pu) mixed particles with various U/Pu atomic ratios were analyzed without prior chemical separation by thermal ionization mass spectrometry (TIMS). Prior to measurement, micron-sized particles with U/Pu ratios of 1, 5, 10
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