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Showing 31-60 of 6327 results for "2858" within Papers
Manuel Valero et al.
Nature neuroscience, 18(9), 1281-1290 (2015-07-28)
Sharp-wave ripples represent a prominent synchronous activity pattern in the mammalian hippocampus during sleep and immobility. GABAergic interneuronal types are silenced or fire during these events, but the mechanism of pyramidal cell (PC) participation remains elusive. We found opposite membrane
Mohammad Mahdi Tavakoli et al.
ACS nano, 9(10), 10287-10295 (2015-08-19)
Flexible thin film solar cells have attracted a great deal of attention as mobile power sources and key components for building-integrated photovoltaics, due to their light weight and flexible features in addition to compatibility with low-cost roll-to-roll fabrication processes. Among
Xiaojun Qiu et al.
Pathology, research and practice, 211(10), 717-725 (2015-08-26)
Overexpression of chaperonin containing t-complex polypeptide 1 (TCP1), or CCT, has been reported in various classes of malignancies. However, little is known about the expression of t-complex protein subunits TCP1theta (CCT8) in gliomas. In this study, the expression of CCT8
Hanne R Johnsen et al.
The New phytologist, 207(3), 805-816 (2015-03-27)
Host plant penetration is the gateway to survival for holoparasitic Cuscuta and requires host cell wall degradation. Compositional differences of cell walls may explain why some hosts are amenable to such degradation while others can resist infection. Antibody-based techniques for
Qingmei Liu et al.
International immunopharmacology, 25(2), 465-473 (2015-03-10)
The prevalence of food allergy has increased in Asian countries. Marine algae have been proposed as the potential resource for anti-allergic therapeutics. The present study was aimed at isolating R-phycocyanin (RPC) from Porphyra haitanensis and determining the anti-allergy potential of
Xiaobing Wang et al.
Biomaterials, 53, 40-49 (2015-04-22)
Human pluripotent stem cells (hPSCs) have the potential to differentiate along the retinal lineage. However, most induction systems are dependent on multiple small molecular compounds such as Dkk-1, Lefty-A, and retinoic acid. In the present study, we efficiently differentiated hPSCs
Mahmoud N Taha et al.
Journal of chromatography. A, 1394, 137-147 (2015-04-08)
Extraction parameters, chemical fingerprint, and the single compounds' activity levels were considered for the selection of active botanicals. For an initial survey, the total bioactivity (i.e., total reducing capacity, total flavonoids contents and free radical scavenging capacity) of 21 aqueous
Andrei V Chernov et al.
The Journal of biological chemistry, 290(18), 11771-11784 (2015-03-21)
To shed light on the early immune response processes in severed peripheral nerves, we performed genome-wide transcriptional profiling and bioinformatics analyses of the proximal (P, regenerating) and distal (D, degenerating) nerve stumps on day 1 in the sciatic nerve axotomy
Erin M Rock et al.
Psychopharmacology, 231(16), 3207-3215 (2014-03-07)
The effectiveness of cannabidiolic acid (CBDA) was compared with other potential treatments for anticipatory nausea (AN), using a rat model of contextually elicited conditioned gaping reactions. The potential of ondansetron (OND), Δ(9)-tetrahydrocannabinol (THC), chlordiazepoxide (CDP), CBDA, and co-administration of CBDA
Nehal Ibrahim et al.
International journal of pharmaceutics, 495(2), 671-679 (2015-09-19)
More than 40 years after its discovery, artemisinin has become the most promising antimalarial agent. However, no intravenous formulation is available due to its poor aqueous solubility. Here, we report the preparation, characterization, and in vitro and in vivo biological
Saikh Mohammad Wabaidur et al.
Journal of separation science, 38(15), 2597-2606 (2015-05-20)
An ultra high performance liquid chromatography with mass spectrometry method has been developed for the simultaneous separation, identification and determination of 22 phenolic constituents in honey from various floral sources from Yemen. Solid-phase extraction was used for extraction of the
Anshul Sharma et al.
Macromolecular bioscience, 15(2), 200-214 (2014-10-11)
Here we report on the modular synthesis and characterization of biodegradable, controlled porous, liquid crystal elastomers (LCE) and their use as three-dimensional cell culture scaffolds. The elastomers were prepared by cross-linking of star block-co-polymers with pendant cholesterol units resulting in
Alice Kujur et al.
Scientific reports, 5, 11166-11166 (2015-06-11)
We identified 44844 high-quality SNPs by sequencing 92 diverse chickpea accessions belonging to a seed and pod trait-specific association panel using reference genome- and de novo-based GBS (genotyping-by-sequencing) assays. A GWAS (genome-wide association study) in an association panel of 211
Auemphon Mordmuang et al.
Nutrients, 7(10), 8503-8517 (2015-10-27)
Bovine mastitis is one of the most important infectious diseases in dairy herds, and staphylococci are the most important etiologic agents of this disease. Antibiotics and chemical agents used in livestock for prevention and cure of the disease can accumulate
Oscar Rodríguez-Espinosa et al.
Immunology, 145(2), 213-224 (2014-12-30)
As part of the innate immune response, neutrophils are at the forefront of defence against infection, resolution of inflammation and wound healing. They are the most abundant leucocytes in the peripheral blood, have a short lifespan and an estimated turnover
Chih-Hung Chiang et al.
Cell transplantation, 24(3), 541-559 (2015-02-11)
Acute hepatic failure (AHF) is a severe liver injury leading to sustained damage and complications. Induced pluripotent stem cells (iPSCs) may be an alternative option for the treatment of AHF. In this study, we reprogrammed human dental pulp-derived fibroblasts into
Constantin Scharlach et al.
Nanomedicine : nanotechnology, biology, and medicine, 11(5), 1085-1095 (2015-02-11)
To further optimize citrate-stabilized VSOPs (very small iron oxide particles, developed for MR angiography) for identification of atherosclerotic plaques, we modified their surface during synthesis using eight other acids for electrostatic stabilization. This approach preserves effective production for clinical application.
Tuo Wang et al.
Nanoscale, 7(1), 77-81 (2014-08-13)
This paper describes the synthesis of Au nanoparticle sensitized ZnO nanopencil arrays on F-doped SnO2 substrates by an aqueous chemical growth and subsequent photoreduction method. The Au-ZnO nanopencil arrays yield a photocurrent of ∼ 1.5 mA cm(-2) at 1 V
William J Horton et al.
Psychopharmacology, 232(14), 2519-2530 (2015-02-24)
While it is known that tobacco use varies across the 24-h day, the time-of-day effects are poorly understood. Findings from several previous studies indicate a potential role for melatonin in these time-of-day effects; however, the specific underlying mechanisms have not
Te-Jin Chow et al.
Bioresource technology, 184, 33-41 (2014-12-03)
In this work, a recombinant cyanobacterium strain with increased photosynthesis rate, cell growth and carbohydrate production efficiency was genetically engineered by co-expressing ictB, ecaA, and acsAB (encoded for bacterial cellulose) in Synechococcus elongatus PCC7942. The resulting cyanobacterial biomass could be
Henrique V Almeida et al.
Advanced healthcare materials, 4(7), 1043-1053 (2015-02-07)
An alternative strategy to the use of in vitro expanded cells in regenerative medicine is the use of freshly isolated stromal cells, where a bioactive scaffold is used to provide an environment conducive to proliferation and tissue-specific differentiation in vivo.
K Bhattacharya et al.
Dalton transactions (Cambridge, England : 2003), 44(19), 9221-9229 (2015-04-25)
Research on energy storage devices has created a niche owing to the ever increasing demand for alternative energy production and its efficient utilisation. Here, a novel composite of Fe3O4 nanospheres and carbon quantum dots (C-dots) have been synthesized by a
Diego Correia et al.
Psychopharmacology, 232(15), 2731-2739 (2015-03-24)
We hypothesized that the corticotropin-releasing factor (CRF) system is hyperresponsive in animals with high ethanol intake, which exhibits a reduction of ethanol intake when administered with a CRF1 receptor antagonist. Outbred Swiss mice were subjected to a long-term, three-bottle, free-choice
Fei Guo et al.
Oncotarget, 6(33), 34606-34616 (2015-09-30)
Suppressor of cytokine signaling 3 (SOCS3) is regarded as a vital repressor in the liver carcinogenesis mainly by inhibiting signal transducer and activator of transcription 3 (STAT3) activity. Farnesoid X Receptor (FXR), highly expressed in liver, has an important role
Mohammad Reza Hashemzadeh et al.
In vitro cellular & developmental biology. Animal, 51(7), 680-689 (2015-06-21)
Rabbit ear wound repair is an accepted model for studies of tissue regeneration, leading to scar less wound repair. It is believed that a specific tissue, blastema, is responsible for such interesting capacity of tissue regeneration. To test this idea
Manuel Sanchez-Alavez et al.
PloS one, 10(8), e0134437-e0134437 (2015-08-20)
Cyclooxygenase inhibitors such as ibuprofen have been used for decades to control fever through reducing the levels of the pyrogenic lipid transmitter prostaglandin E2 (PGE2). Historically, phospholipases have been considered to be the primary generator of the arachidonic acid (AA)
Jordan Plieskatt et al.
BMC cancer, 15, 309-309 (2015-04-24)
Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive tumor of the bile duct, and a significant public health problem in East Asia, where it is associated with infection by the parasite Opisthorchis viverrini. ICC is often detected at an advanced stage
Huanqing Li et al.
OncoTargets and therapy, 8, 3245-3253 (2015-11-26)
To investigate the role of miR-21 in cyclooxygenase-2 inhibitor NS398-induced apoptosis and invasion in gastric cancer (GC) cells. AGS cells were treated with NS398 and transfected with miR-21. Quantitative real-time polymerase chain reaction was used to measure miR-21 mRNA expression.
Neelima M Bhat et al.
Journal of immunology (Baltimore, Md. : 1950), 195(11), 5178-5188 (2015-10-28)
B cell binding and cytotoxicity by human VH4-34-encoded Abs of the IgM isotype has been well documented. A VH4-34-IgM has recently shown a favorable early response in a phase 1 trial for treatment of B cell acute lymphoblastic leukemia. Although
B Rasti et al.
Journal of liposome research, 24(2), 99-105 (2013-10-09)
This study presents the application of the response surface methodology (design) to develop an optimal preparation condition (independent variables) namely shear rate (600-1000 rpm), mixing time (30-60 min), and sonication time (10-20 min) for polyunsaturated fatty acids (docosahexaenoic acid and
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