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Showing 1-30 of 144 results for "307823" within Papers
Elle Chadwick et al.
Poultry science, 99(11), 5324-5330 (2020-11-05)
Sodium bisulfate (SB) was evaluated on its ability to improve broiler growth and intestinal structure with(out) a coccidia challenge. One thousand two hundred Cobb500 day-old males were randomly assigned within 4 experimental groups with a 2 × 2 factorial design, with (out)
Juan Ma et al.
Oncology reports, 43(6), 1805-1818 (2020-04-03)
BarH‑like homeobox 2 (BARX2), a homeobox gene, is associated with several types of cancers. The present study aimed to determine whether DNA methylation downregulates BARX2 expression and whether BARX2 is associated with suppression of gastric carcinogenesis. BARX2 protein expression in normal
Hiroyuki Aihara et al.
International journal of colorectal disease, 28(1), 83-87 (2012-09-27)
This pilot study sought to investigate the performance and safety of a reduced-volume oral sulfate solution for use as a bowel-cleansing regimen prior to colonoscopy in a Japanese population. Subjects followed a prescribed split-dose regimen in which the first portion
Cuilan Zhang et al.
The Analyst, 145(2), 537-543 (2019-11-26)
The sensitive and on-site detection of sulfur dioxide (SO2) is in great demand in the fields of food safety and environmental protection. Here, we developed a novel upconversion nanoprobe based on the luminescence energy transfer mechanism for monitoring the atmospheric
Mingtian Deng et al.
DNA and cell biology, 39(4), 572-578 (2020-02-20)
DNA methylation inhibitor or loss and gain of function of DNA methylation key players were widely used to investigate the regulation of X inactive-specific transcript (Xist) expression by DNA methylation, which results in global change of DNA methylation. Here, we
Jianqing Chen et al.
Pharmaceutical research, 31(10), 2810-2821 (2014-05-23)
To assess the application of succinimidyl iodobenzoate (SIB) iodination method in labeling biotherapeutics to study their pharmacokinetics (PK) and biodistribution. An IgG molecule (protein-01) and a 40 KDa protein (protein-02) were evaluated. Pharmacokinetics (PK) and biodistribution of the radiolabeled IgG ((125)I-protein-01)
Chang-Ling Li et al.
Journal of molecular and cellular cardiology, 139, 98-112 (2020-01-27)
Salvianolic acid B (Sal B) is the representative component of phenolic acids derived from the dried root and rhizome of Salvia miltiorrhiza Bge. (Labiatae), which has been widely used for the treatment of cardiovascular and cerebrovascular diseases. However, the effect
Joe Yamamoto et al.
Journal of neural transmission (Vienna, Austria : 1996), 128(1), 27-36 (2020-11-03)
In the pharmacotherapy of patients with Parkinson's disease (PD), entacapone reduces the peripheral metabolism of L-dopa to 3-O-methyldopa (3-OMD), thereby prolonging the half-life (t1/2) of L-dopa and increasing the area under the concentration curve (AUC). The effect of entacapone on
Jian Zhang-van Enk et al.
Molecular pharmaceutics, 10(2), 619-630 (2012-12-22)
The thermal unfolding and subsequent aggregation of the unglycosylated Fc fragment of a human IgG1 antibody (Fc) were studied in the salt solutions of Na(2)SO(4), KF, KCl and KSCN at pH 4.8 and 7.2 below and at its pI of
Daniel Ejim Uti et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 124, 109879-109879 (2020-01-29)
African walnuts were previously shown to modulate hepatic lipid bio-accumulation in obesity. Herein, we investigated the impact of the nuts on fat accumulation in adipose and ectopic regions, and associated oxidatiive stress status in obese rats. Whole ethanol extract (WE)
Viswanath R K Vadapalli et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(8), 933-938 (2013-03-15)
Sulphate removal from sodium sulphate-rich brine using barium hydroxide and recovery of the barium salts has been investigated. The sodium sulphate-rich brine treated with different dosages of barium hydroxide to precipitate barium sulphate showed sulphate removal from 13.5 g/L to
Glycosylation profiles determine extravasation and disease-targeting properties of armed antibodies.
Dario Venetz et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(7), 2000-2005 (2015-02-04)
The ability of antibodies to extravasate out of blood vessels is critical for therapeutic activity, because molecular targets for most diseases are located outside of the endothelial lining. By performing detailed biodistribution studies with a novel IL9-armed cancer-specific antibody, we
Ye-Young Rhee et al.
Virchows Archiv : an international journal of pathology, 466(6), 675-683 (2015-03-17)
In carcinogenesis of peripheral pulmonary carcinomas, multiple genetic and epigenetic alterations are involved. In this study, we quantified methylation levels of repetitive DNA elements (L1 and Alu) and six CpG island methylator phenotype (CIMP)-panel markers in various lesions representing steps
Jing Lai et al.
Oncotarget, 5(16), 6909-6922 (2014-07-30)
To understand the transcriptional regulation of p73 by promoter methylation and Nrf-2 in breast carcinogenesis, ChIP assay indicated that Nrf-2 can bind to both promoters and can activate the transcription of TAp73 and ΔNp73 in MCF-7 cell line, knockdown of
C Poelaert et al.
Journal of animal science, 90 Suppl 4, 387-389 (2013-02-13)
Over the past decade, several in vitro methods have been developed to study intestinal fermentation in pigs and its influence on health. In these methods, samples are fermented by a bacterial inoculum diluted in a mineral buffer solution. Generally, a
Yao-Fei Pei et al.
Oncotarget, 8(14), 23155-23166 (2017-04-21)
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved
Xinyu Liu et al.
Biochimica et biophysica acta. Molecular basis of disease, 1864(9 Pt B), 2835-2844 (2018-05-29)
IRX1 is originally characterized as a tumor suppressor gene of gastric cancer (GC) by our group based on serially original studies. However, the molecular regulatory mechanisms of IRX1 are not clear yet. Here, we identified protein arginine methyltransferase 5 (PRMT5)
Clément Cartier et al.
Water research, 47(2), 661-671 (2012-11-24)
Release of lead from 80% partially replaced service lines was compared to full lead service lines using harvested-stabilized lead pipes and field brass connectors. After more than a year of stabilization, lead release was consistent with field samples. Over the
Se-Ho Park et al.
Journal of microbiology and biotechnology, 29(1), 114-126 (2018-12-07)
This paper introduces three ways to determine host-guest complexation of cucurbit[7]uril (CB[7]) with homocysteine (Hcy). After preincubating Hcy and cysteine (Cys) with CB[7], Ellman's reagent (DTNB) was used to detect Hcy and Cys. Only Cys reacted with DTNB and Hcy
Yanfeng Liu et al.
Toxicology in vitro : an international journal published in association with BIBRA, 52, 321-331 (2018-07-22)
The purpose of present study was to investigate the applicability of reconstructed human epidermis model to identify skin corrosive UN GHS Categories 1A, 1B/1C and non-corrosive chemicals in China. By using a commercialized reconstructed human epidermis model, China EpiSkin™ which
M Sato et al.
Veterinary and comparative oncology, 16(3), 409-415 (2018-03-13)
Death-associated protein kinase (DAPK) is a serine/threonine kinase and a tumour suppressor gene. Diffuse large B-cell lymphomas with inactivated DAPK through hypermethylation of a CpG island is known to result in a biologically aggressive phenotype in humans. This retrospective study
Gautam Das et al.
Journal of nanoscience and nanotechnology, 14(6), 4455-4461 (2014-04-18)
The present study reports the use of water soluble sodium sulfate (Na2SO4) nanorods as a versatile template for generation of tubular copper sulfide (CuS) nanostructures. The Na2SO4 nanorods were synthesized from ammonium sulfate (NH4)2SO4 and sodium hydroxide (NaOH), under refluxing
Gizem Karaca et al.
Environmental technology, 35(13-16), 1840-1850 (2014-06-25)
In the present study, removal of polycyclic aromatic hydrocarbons (PAHs) from synthetic solid matrices with various methods was investigated. PAH removal experiments were conducted in a specifically designed UV apparatus for this study. Polyurethane foams (PUF) cartridges were used to
Junwei Tang et al.
Cell death & disease, 8(3), e2675-e2675 (2017-03-17)
The retinoblastoma gene (RB1), a known tumor-suppressor gene (TSG), was decreased in multiple cancers including hepatocellular carcinoma (HCC). Here we focused on the bidirectional transcripted long noncoding RNA (Linc00441) with neighbor gene RB1 to investigate whether Linc00441 is involved in
Yueping Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 48(10), 841-848 (2020-07-30)
Probenecid (PROB) is a clinical probe inhibitor of renal organic anion transporter (OAT) 1 and OAT3 that inhibits in vitro activity of hepatic drug transporters OATP1B1 and OATP1B3. It was hypothesized that PROB could potentially affect the disposition of OATP1B
Yunwei Lou et al.
Journal of immunology (Baltimore, Md. : 1950), 193(3), 1064-1070 (2014-06-29)
Both commensal bacteria and infiltrating inflammatory cells play essential roles in the pathogenesis of inflammatory bowel disease. The molecular mechanisms whereby these pathogenic factors are regulated during the disease are not fully understood. We report in this article that a
H Ramebäck et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 164, 109293-109293 (2020-08-21)
A method for the measurement of the isotopic composition and time since last chemical separation (age) of plutonium is presented. The method includes alpha spectrometric measurement of 238Pu, 239Pu and 240Pu where the ratio of 239Pu and 240Pu was determined
S E Cloft et al.
Poultry science, 98(10), 5005-5016 (2019-06-05)
A study was conducted to determine if increasing digestible (dig) amino acid (AA) density or feed allocation of starter diets fed to broilers receiving coccidiosis vaccination can ameliorate poor cumulative growth performance and reduce meat yield. A total of 1,600
Sagnik Chatterjee et al.
The Journal of pharmacology and experimental therapeutics, 376(1), 29-39 (2020-11-01)
Expression and functional changes in the organic anion transporting polypeptide (OATP)-multidrug resistance-associated protein (MRP) axis of transporters are well reported in patients with nonalcoholic steatohepatitis (NASH). These changes can impact plasma and tissue disposition of endo- and exogenous compounds. The
Nisreen Al-Moghrabi et al.
Clinical epigenetics, 10(1), 99-99 (2018-07-28)
Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmission of BRCA1 and MGMT promoter methylations in mother-newborn pairs.
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