322M-1

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Showing 1-11 of 11 results for "322M-1" within Papers

Trials of new germ cell immunohistochemical stains in 93 extragonadal and metastatic germ cell tumors.

Kenneth A Iczkowski et al.

Human pathology, 39(2), 275-281 (2007-11-30)

Organic cation transporter 3/4 (OCT3/4) is a transcription factor of embryonic stem cells; c-kit (CD117) is a tyrosine kinase receptor implicated in seminoma carcinogenesis. Their reactivity is well characterized in testicular, but not extragonadal and metastatic, germ cell tumors. A

Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomas.

Folker E Franke et al.

Journal of cutaneous pathology, 31(5), 362-367 (2004-04-03)

Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial

Detection of lymphatic invasion in primary melanoma with monoclonal antibody D2-40: a new selective immunohistochemical marker of lymphatic endothelium.

Firouzeh Niakosari et al.

Archives of dermatology, 141(4), 440-444 (2005-04-20)

To identify the presence of lymphatic invasion in primary cutaneous melanoma using monoclonal antibody D2-40, a marker of lymphatic endothelium, and to correlate the presence of lymphatic invasion with other clinicopathologic characteristics of the tumors. Retrospective melanoma case series study

Utility of D2-40, a novel mesothelial marker, in the diagnosis of malignant mesothelioma.

Albert Y Chu et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(1), 105-110 (2004-09-25)

Although immunohistochemistry has proven to be valuable in the differentiation of epithelioid mesothelioma from pulmonary or metastatic adenocarcinoma, no single antibody has demonstrated absolute sensitivity or specificity in making this distinction. Using immunohistochemical analysis with D2-40, a recently available monoclonal

Identification of lymphatic vessels in malignant, adenomatous and normal colonic mucosa using the novel immunostain D2-40.

F Fogt et al.

Oncology reports, 11(1), 47-50 (2003-12-05)

Distribution of lymphatic vessels in normal and neoplastic colon has been previously analyzed with electron microscopic techniques, as reliable antibodies have not been available for selective lymph vessel staining. A novel monoclonal antibody, D2-40, is recently available to differentiate lymphatic

Identification of lymphatic endothelium in pediatric vascular tumors and malformations.

Csaba Galambos et al.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 8(2), 181-189 (2005-02-19)

The distinction between lymphatic and other vascular vessels on microscopic sections is a challenging task. D2-40, a novel antibody, has been reported to be selective for lymphatic endothelium. We studied the specificity and sensitivity of D2-40 in pediatric vascular tumors

Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas.

Harriette J Kahn et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 15(4), 434-440 (2002-04-16)

There is controversy over the histogenesis of Kaposi's sarcoma (KS) from lymphatic or blood vessel endothelium. D2-40 is a novel monoclonal antibody to an Mr 40,000 O-linked sialoglycoprotein that reacts with a fixation-resistant epitope on lymphatic endothelium. We sought to

Podoplanin: a novel diagnostic immunohistochemical marker.

Nelson G Ordóñez

Advances in anatomic pathology, 13(2), 83-88 (2006-05-04)

Podoplanin is a transmembrane mucoprotein recognized by the recently commercially available D2-40 monoclonal antibody. Recent investigations have shown that podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable

D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma.

Nelson G Ordóñez

Human pathology, 36(4), 372-380 (2005-05-14)

Recent investigations have shown that podoplanin and the D2-40 monoclonal antibody, which reacts with an oncofetal antigen present in fetal germ cells, are highly reliable lymphatic endothelial markers. The observation that both of these markers are also expressed in normal

D2-40 immunohistochemistry--so far!

Alexandra N Kalof et al.

Advances in anatomic pathology, 16(1), 62-64 (2008-12-23)

D2-40 is a commercially available monoclonal antibody directed against human podoplanin, a transmembrane mucoprotein that is expressed in lymphatic endothelial cells. Since its introduction, D2-40 immunoexpression has been described in a variety of lymphovascular neoplasms including lymphangioma, Kaposi sarcoma, and

Expression of D2-40 in lymphatic endothelium of normal tissues and in vascular tumours.

M Fukunaga

Histopathology, 46(4), 396-402 (2005-04-07)

To evaluate the expression of D2-40 in normal lymphatic endothelium and vascular tumours or tumour-like lesions of the skin and soft tissue. D2-40 is a novel monoclonal antibody to a Mr 40 000 O-linked sialoglycoprotein that reacts with a fixation-resistant

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