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Showing 1-30 of 264 results for "328634" within Papers
Mathew K John et al.
Anticancer research, 33(10), 4285-4291 (2013-10-15)
Poor solubility and bioavailability are limiting factors for the clinical application of curcumin. The objective of the current study was to develop a liquid formulation with increased solubility and systemic bioavailability. A co-solvent formulation with increased solubility of 20 mg/ml
Giuseppe Genduso et al.
Polymers, 11(2) (2019-04-10)
A triptycene-based diamine, 1,3,6,8-tetramethyl-2,7-diamino-triptycene (TMDAT), was used for the synthesis of a novel solution-processable polyamide obtained via polycondensation reaction with 4,4'-(hexafluoroisopropylidene)bis(benzoic acid) (6FBBA). Molecular simulations confirmed that the tetrasubstitution with ortho-methyl groups in the triptycene building block reduced rotations around
C Neveu et al.
British journal of pharmacology, 171(19), 4425-4439 (2014-06-11)
The neuropeptide 26RFa and its cognate receptor GPR103 are involved in the control of food intake and bone mineralization. Here, we have tested, experimentally, the predicted ligand-receptor interactions by site-directed mutagenesis of GPR103 and designed point-substituted 26RFa analogues. Using the
Sa Li et al.
Nature communications, 6, 7872-7872 (2015-08-06)
Alloy-type anodes such as silicon and tin are gaining popularity in rechargeable Li-ion batteries, but their rate/cycling capabilities should be improved. Here by making yolk-shell nanocomposite of aluminium core (30 nm in diameter) and TiO2 shell (∼3 nm in thickness), with a
Yun Ping Neo et al.
Journal of agricultural and food chemistry, 62(22), 5163-5172 (2014-05-16)
Effects of heat treatment on structure and physicochemical properties of zein (Ze) and gallic acid loaded zein (Ze-GA) electrospun fiber mats were investigated. The electrospun fiber mats displayed different surface and physicochemical properties after being heat-cured at 150 °C for
M Melusova et al.
Neoplasma, 61(6), 690-699 (2014-10-25)
For several thousand years natural products were successfully used to treat a variety of diseases and to maintain health in humans, but until now it is not fully known what causes these medicinal effects. In our study we assessed the cytotoxic
Jong Guk Kim et al.
ChemSusChem, 8(10), 1752-1760 (2015-04-25)
A hybrid composite system of MnCo2 O4 nanowires (MCO NWs) anchored on reduced graphene oxide (RGO) nanosheets was prepared as the bifunctional catalyst of a Li-O2 battery cathode. The catalysts can be obtained from the hybridization of one-dimensional MCO NWs
Shengnan Yang et al.
Chemosphere, 244, 125525-125525 (2019-12-08)
In this study, electrooxidation of the tetracycline hydrolysis products was investigated using a carbon nanotube (CNT) electrochemical filter and 4-epianhydrochlortetracycline (EACTC) as a model compound. Electrochemical filtration of 10 μmol L-1 EACTC at a voltage of 2.5 V and a flow rate of
Monica Benincasa et al.
European journal of medicinal chemistry, 95, 210-219 (2015-03-31)
The proline-rich antibacterial peptide Bac7(1-35) protects mice against Salmonella typhimurium infection, despite its rapid clearance. To overcome this problem the peptide was linked to a polyethylene glycol (PEG) molecule either via a cleavable ester bond or via a non-hydrolysable amide
Dexian Dong et al.
PloS one, 10(6), e0129130-e0129130 (2015-06-13)
Specific environmental stresses may lead to induced genomic instability in bacteria, generating beneficial mutants and potentially accelerating the breeding of industrial microorganisms. The environmental stresses inside the aqueous battery may be derived from such conditions as ion shuttle, pH gradient
Chao Zhao et al.
Nature communications, 5, 5079-5079 (2014-10-07)
The remarkable stability of peptide nucleic acids (PNAs) towards enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device. Here we report the development of chemically engineered PNAs for the quantitative detection of HIV
Misu Lee et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(14), 3204-3215 (2015-04-04)
Novel therapeutic approaches are needed to improve the postoperative management of residual nonfunctioning pituitary adenomas (NFPA), given their high relapse rate. Here, we evaluated the antitumor efficacy of the dual PI3K/mTOR inhibitor NVP-BEZ235 in the only available model of spontaneous
Sanghamitra Neogi et al.
ACS nano, 9(4), 3820-3828 (2015-04-02)
A detailed understanding of the connections of fabrication and processing to structural and thermal properties of low-dimensional nanostructures is essential to design materials and devices for phononics, nanoscale thermal management, and thermoelectric applications. Silicon provides an ideal platform to study
Mei Zhang et al.
Polymers, 12(7) (2020-07-16)
Transparent polyimides (PI) films with outstanding overall performance are attractive for next generation optoelectronic and microelectronic applications. Semi-alicyclic PIs derived from alicyclic dianhydrides and aromatic diamines have proved effective to prepare transparent PIs with high transmittance. To optimize the combined
Marina Pierdominici et al.
Particle and fibre toxicology, 11, 74-74 (2014-12-17)
Diesel exhaust particles (DEP) are major constituents of ambient air pollution and their adverse health effect is an area of intensive investigations. With respect to the immune system, DEP have attracted significant research attention as a factor that could influence
Geoff J Dumsday et al.
Biotechnology and bioengineering, 102(3), 673-683 (2008-12-19)
Arising from the requirement for discovery of novel biocatalysts with unusual properties, a process was developed which uniquely combines aspects of continuous culture with the measurement of oxygen uptake. This adaptation of the chemostat can be used to facilitate the
Eunjae Jung et al.
International journal of pharmaceutics, 487(1-2), 49-55 (2015-04-12)
The aim of this study was to develop drug-in adhesive (DIA) patch formulations for the transdermal delivery of fluoxetine (FX). The DIA patch formulations containing FX were prepared and optimized with various pressure sensitive adhesives, drug contents and enhancers. Among
Bin Liu et al.
ChemSusChem, 8(21), 3697-3703 (2015-10-13)
The development of highly efficient catalysts is critical for the practical application of lithium-oxygen (Li-O2) batteries. Nanosheet-assembled ZnCo2O4 (ZCO) microspheres and thin films grown in situ on single-walled carbon nanotube (ZCO/SWCNT) composites as high-performance air electrode materials for Li-O2 batteries are
Biljana Mojsoska et al.
Antimicrobial agents and chemotherapy, 59(7), 4112-4120 (2015-05-06)
The constant emergence of new bacterial strains that resist the effectiveness of marketed antimicrobials has led to an urgent demand for and intensive research on new classes of compounds to combat bacterial infections. Antimicrobial peptoids comprise one group of potential
Biao Chen et al.
Nanoscale, 7(30), 12895-12905 (2015-07-15)
Uniform transition metal sulfide deposition on a smooth TiO2 surface to form a coating structure is a well-known challenge, caused mainly due to their poor affinities. Herein, we report a facile strategy for fabricating mesoporous 3D few-layered (<4 layers) MoS2
Luis Solorio et al.
Journal of pharmaceutical sciences, 104(10), 3471-3480 (2015-07-16)
Phase-sensitive in situ forming implants (ISFI) are a promising platform for the controlled release of therapeutic agents. The simple manufacturing, ease of placement, and diverse payload capacity make these implants an appealing delivery system for a wide range of applications.
Qihui Qian et al.
ACS applied materials & interfaces, 11(34), 31257-31269 (2019-08-01)
Mixed-matrix membranes (MMMs) formed by dispersing metal-organic framework (MOF) particles in polymers have attracted significant attention because these composite systems can potentially surpass the separation performance of pure polymers alone. However, performance improvements are often unrealized because of poor interfacial
Yong Li et al.
International journal of pharmaceutics, 486(1-2), 207-216 (2015-04-07)
In this work, poorly water soluble phytochemical ellagic acid (EA) was micronized to increase its solubility and thereby the bioavailability during antisolvent precipitation process using N-methyl pyrrolidone (NMP) as solvent and deionized water as antisolvent. The micronized EA (m-EA) freeze-dried
Prakash Ramalingam et al.
Pharmaceutical research, 32(2), 389-402 (2014-08-02)
Solid lipid nanoparticles (SLNs) have been proposed as a colloidal carrier system that could enhance the oral bioavailability of curcumin. However, a burst release of the loaded drug, which occurs in acidic environments, has been a main obstacle to the
Yanying Lu et al.
Nanoscale, 7(6), 2770-2776 (2015-01-15)
In this paper, we report on the synthesis of micro-nanostructured CuO/C spheres by aerosol spray pyrolysis and their application as high-performance anodes in sodium-ion batteries. Micro-nanostructured CuO/C spheres with different CuO contents were synthesized through aerosol spray pyrolysis by adjusting
Red phosphorus-single-walled carbon nanotube composite as a superior anode for sodium ion batteries.
Yujie Zhu et al.
ACS nano, 9(3), 3254-3264 (2015-03-05)
Sodium ion batteries (SIBs) have been considered as a top alternative to lithium ion batteries due to the earth abundance and low cost of sodium compared with lithium. Among all proposed anode materials for SIBs, red phosphorus (P) is a
Brinda Alagesan et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(2), 396-404 (2014-10-29)
Improved therapeutic approaches are needed for the treatment of pancreatic ductal adenocarcinoma (PDAC). As dual MEK and PI3K inhibition is presently being used in clinical trials for patients with PDAC, we sought to test the efficacy of combined targeting of
Thirupathi Ravula et al.
Langmuir : the ACS journal of surfaces and colloids, 33(40), 10655-10662 (2017-09-19)
The development and applications of detergent-free membrane mimetics have been the focus for the high-resolution structural and functional studies on membrane proteins. The introduction of lipid nanodiscs has attracted new attention toward the structural biology of membrane proteins and also
Hussein N Yassine et al.
PloS one, 10(1), e0115320-e0115320 (2015-01-22)
Using mass spectrometric immunoassay, the abundance of SAA truncations relative to the native variants was examined in plasma of 91 participants with type 2 diabetes and chronic kidney disease and 69 participants without diabetes. The ratio of SAA 1.1 (missing
Courtney H Fox et al.
Nature communications, 6, 7417-7417 (2015-07-16)
Dynamic covalent materials are stable materials that possess reversible behaviour triggered by stimuli such as light, redox conditions or temperature; whereas supramolecular crosslinks depend on the equilibrium constant and relative concentrations of crosslinks as a function of temperature. The combination
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