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Showing 1-30 of 92 results for "365548" within Papers
Stefan Rudloff et al.
Nature communications, 12(1), 549-549 (2021-01-24)
Intrauterine growth restriction (IUGR) is associated with reduced kidney size at birth, accelerated renal function decline, and increased risk for chronic kidney and cardiovascular diseases in adults. Precise mechanisms underlying fetal programming of adult diseases remain largely elusive and warrant
Awal M Hadi et al.
Cellular oncology (Dordrecht), 34(4), 343-354 (2011-05-04)
Fibrosis is associated with various cardiac pathologies and dysfunction. Current quantification methods are time-consuming and laborious. We describe a semi-automated quantification technique for myocardial fibrosis and validated this using traditional methods. Pulmonary Hypertension (PH) was induced in adult Wistar rats
P A Will et al.
PloS one, 15(7), e0235965-e0235965 (2020-07-24)
Secondary lymphedema (SL)is a frequent and devastating complication of modern oncological therapy and filarial infections. A lack of a reliable preclinical model to investigate the underlying mechanism of clinical stage progression has limited the development of new therapeutic strategies. Current
Picrosirius red staining revisited.
Raymond Coleman
Acta histochemica, 113(3), 231-233 (2010-03-02)
In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis.
George J, et al.
Proceedings of the National Academy of Sciences of the USA, 96(22), 12719-12724 (1999)
J-Y Zhang et al.
International journal of oral and maxillofacial surgery, 40(11), 1296-1300 (2011-07-12)
Epithelial-mesenchymal interactions are thought to play an important role in the pathogenesis of odontogenic lesions. Keratocystic odontogenic tumour (KCOT) is a benign cystic neoplasm with a characteristic parakeratinized epithelial lining, which differs histologically and behaviourally from the so-called orthokeratinized odontogenic
Gopala K Yakala et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(3), 387-401 (2019-01-18)
Objective- Atherosclerotic coronary artery disease is the leading cause of death worldwide, and current treatment options are insufficient. Using systems-level network cluster analyses on a large coronary artery disease case-control cohort, we previously identified PCSK3 (proprotein convertase subtilisin/kexin family member
Nozomu Yamauchi et al.
Journal of endodontics, 37(12), 1636-1641 (2011-11-22)
In a previous report, we showed that 2 types of mineralized tissues were formed in the canal spaces of dogs after tissue engineering treatments of immature teeth with apical periodontitis: (1) dentin- associated mineralized tissue (DAMT) and (2) bony islands
Anuradha Krishnan et al.
The American journal of pathology, 190(6), 1284-1297 (2020-04-03)
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL; TNFSF10) receptor (TR) is a pro-apoptotic receptor whose contribution to chronic cholestatic liver disease is unclear. Herein, we examined TRAIL receptor signaling in a mouse model of cholestatic liver injury. TRAIL receptor-deficient (Tnsf10
Irit Allon et al.
Acta histochemica, 113(8), 803-809 (2011-03-08)
We conducted a comprehensive study of all lipomatous tumors of the oral mucosa (1996-2008) accessioned at the Department of Oral Pathology, Tel Aviv University, collected demographic data and analyzed multiple histomorphological features. Furthermore, we examined the immunostaining of aP2 (adipocyte
Paulo Sérgio Bossini et al.
Journal of tissue engineering and regenerative medicine, 5(3), 229-237 (2010-10-07)
The aim of this study was to investigate the effects of a novel bioactive material (Biosilicate®) and low-level laser therapy (LLLT) on bone fracture consolidation in osteoporotic rats. Forty female Wistar rats were submitted to ovariectomy (OVX) to induce osteopenia.
Tohid Rezaei Topraggaleh et al.
Biomaterials science, 7(4), 1422-1436 (2019-01-23)
Extracellular matrix-derived scaffolds provide an efficient platform for the generation of organ-like structures. Successful development of testicular organoids (TOs) with the capability of supporting complete spermatogenesis has not been reported yet. Here, we have developed an optimized method for the
Zeeshan H Syedain et al.
Journal of biomechanics, 44(5), 848-855 (2011-01-22)
Cyclic stretching and growth factors like TGF-β have been used to enhance extracellular matrix (ECM) production by cells in engineered tissue to achieve requisite mechanical properties. In this study, the effects of TGF-β1 were evaluated during long-term cyclic stretching of
Sabatini M, et al.
Cartilage and Osteoarthritis (2004)
Víctor S Carriel et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 59(3), 270-277 (2011-03-08)
For the histopathologic diagnosis of melanocytic lesions, it could be necessary to identify the melanin pigment because its visualization is unspecific with hematoxylin-eosin (HE). The Fontana-Masson (FM) technique is used in histopathology in this type of lesion, which allows the
Christin Elßner et al.
Gastroenterology, 156(4), 1190-1205 (2018-11-18)
Cholangiocyte proliferation and ductular reaction contribute to the onset and progression of liver diseases. Little is known about the role of the transcription factor nuclear factor-κB (NF-κB) in this process. We investigated the activities of the RELB proto-oncogene NF-κB subunit
Hiroyuki Yamaguchi et al.
Biochemical and biophysical research communications, 533(4), 739-744 (2020-09-30)
Intraflagellar transport (IFT) is essential for assembling primary cilia required for bone formation. Disruption of IFT frequently leads to bone defects in humans. While it has been well studied about the function of IFT in osteogenic cell proliferation and differentiation
Gian Nutal Schädli et al.
Communications biology, 4(1), 110-110 (2021-01-27)
Progress in bone scaffold development relies on cost-intensive and hardly scalable animal studies. In contrast to in vivo, in vitro studies are often conducted in the absence of dynamic compression. Here, we present an in vitro dynamic compression bioreactor approach
Sukhwinder Singh et al.
Biodegradation, 21(4), 501-511 (2009-12-05)
Decolourization of Direct Red 80 (DR-80) by the white rot fungus Phanerochaete chrysosporium MTCC 787 was investigated employing sequential design of experiments. Media components for growing the white rot fungus were first screened using Plackett-Burman design and then optimized using
Hui-Chao Tao et al.
Frontiers in immunology, 11, 148-148 (2020-03-12)
Inflammation is one of the hallmarks of non-alcoholic steatohepatitis. CD47 is a widely expressed transmembrane protein that signals through inhibitory receptor signal regulatory protein α (SIRPα) to inhibit macrophage activation and phagocytosis. In this study, we sought to investigate the
Christopher A Miller et al.
Circulation. Cardiovascular imaging, 6(3), 373-383 (2013-04-05)
Extracellular matrix expansion is a key element of ventricular remodeling and a potential therapeutic target. Cardiovascular magnetic resonance (CMR) T1-mapping techniques are increasingly used to evaluate myocardial extracellular volume (ECV); however, the most widely applied methods are without histological validation.
Ruchieka Vij et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 40(3), 257-262 (2010-10-26)
The purpose of this study was to evaluate the nature of collagen in the connective tissue walls of odontogenic cysts, like the odontogenic keratocyst (OKC), dentigerous cyst and radicular cyst using picrosirius red stained sections. Furthermore, it was intended to
Jodi F Evans et al.
Molecular and cellular endocrinology, 355(1), 60-70 (2012-02-07)
A local melanocortin system is active during tissue injury and inflammation. Thus far this system has been described as autocrine in nature where local production of pro-opiomelanocortin (POMC) peptides by leukocytes feeds back on melanocortin receptor (MC-R) expressing immune cells
Catherine Cannet et al.
International journal of legal medicine, 125(4), 493-502 (2010-04-07)
Estimation of age at death from human bones in legal medicine or in anthropology and archaeology is hampered by controversial results from the various macroscopic and histological techniques. This study attempted an estimation of age at death by histomorphometric analysis
K'Shylah S Whitehurst et al.
International journal of molecular sciences, 21(16) (2020-08-23)
EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at the time of coronary artery
R Byberg et al.
Environmental science and pollution research international, 20(6), 3570-3581 (2013-02-21)
The photocatalytic degradation of a series of six acid dyes (Direct Red 80, Direct Red 81, Direct Red 23, Direct Violet 51, Direct Yellow 27, and Direct Yellow 50) has been tested compared in terms of color removal, mineralization, and
Emmanuel Nwadozi et al.
Acta physiologica (Oxford, England), 229(1), e13449-e13449 (2020-02-06)
Critical limb ischaemia (CLI) is characterized by inadequate angiogenesis, arteriolar remodelling and chronic myopathy, which are most severe in type 2 diabetic patients. Hypertriglyceridaemia, commonly observed in these patients, compromises macrovascular function. However, the effects of high-fat diet-induced increases in
Prakash Doddapattar et al.
Arteriosclerosis, thrombosis, and vascular biology, 40(7), 1738-1747 (2020-05-22)
The extracellular matrix of atherosclerotic arteries contains abundant deposits of cellular Fn-EDA (fibronectin containing extra domain A), suggesting a functional role in the pathophysiology of atherosclerosis. Fn-EDA is synthesized by several cell types, including endothelial cells (ECs) and smooth muscle
Ming Yi et al.
Journal of hematology & oncology, 14(1), 27-27 (2021-02-18)
Therapeutic antibodies targeting programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis induce potent and durable anti-tumor responses in multiple types of cancers. However, only a subset of patients benefits from anti-PD-1/PD-L1 therapies. As a negative regulator of anti-tumor
Injoo Hwang et al.
Cell & bioscience, 11(1), 3-3 (2021-01-08)
Hepatic stellate cells (HSCs) are activated in response to liver injury with TIF1γ-suppression, leading to liver fibrosis. Here, we examined the mechanism how reduction of TIF1γ in HSCs induces damage on hepatocytes and liver fibrosis. Lrat:Cas9-ERT2:sgTif1γ mice were treated Tamoxifen
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