36766

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Showing 1-27 of 27 results for "36766" within Papers

Chemical oxidation of 2,6-dimethylaniline by electrochemically generated Fenton's reagent.

Nalinrut Masomboon et al.

Journal of hazardous materials, 176(1-3), 92-98 (2009-12-08)

Oxidation of 2,6-dimethylaniline by electro-Fenton process in acidic solution at pH 2 was investigated. The effects of pH, Fe(2+), H(2)O(2) and current density were assessed to determine the optimum operating parameters. The oxidation efficiency of 2,6-dimethylaniline was determined by the

Effect of carrier composition on 2,6-dimethylaniline degradation in aqueous solution by fluidized-bed Fenton process.

Chavalit Ratanatamskul et al.

Environmental technology, 32(11-12), 1233-1237 (2011-10-06)

The fluidized-bed Fenton process is an alternative process that decreases iron sludge from the Fenton reaction by using carriers to crystallize iron on to the surface of the carrier. In this study, the target compound is 2,6-dimethylaniline, which is a

Further investigations into the genotoxicity of 2,6-xylidine and one of its key metabolites.

David Kirkland et al.

Regulatory toxicology and pharmacology : RTP, 62(1), 151-159 (2011-09-20)

The metabolite of several amide anaesthetics, 2,6-xylidine, is a possible human (Group 2B) carcinogen and induced nasal tumours in rats after dietary administration. However, published papers on the genotoxicity of 2,6-xylidine in vitro have given inconsistent results. It has been

Oxidation of 2,6-dimethylaniline by the Fenton, electro-Fenton and photoelectro-Fenton processes.

Wang-Ping Ting et al.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 46(10), 1085-1091 (2011-08-03)

Fenton technologies for wastewater treatment have demonstrated their effectiveness in eliminating toxic compounds. This study examines how hydrogen peroxide concentration and ultraviolet (UV) light affects oxidation processes. However, total mineralization through these Fenton technologies is expensive compared with biological technologies.

Chemical oxidation of 2,6-dimethylaniline in the fenton process.

Nalinrut Masomboon et al.

Environmental science & technology, 43(22), 8629-8634 (2009-12-24)

2,6-Dimethylaniline degradation by Fenton process has been studied in depth for the purpose of learning more about the reactions involved in the oxidation of 2,6-dimethylaniline under various reaction conditions. The effect of reaction conditions including the initial pH value, and

Liquid phase overtone spectral investigations of 2,6-dimethylaniline and 2,4-dimethylaniline-evidence for steric nature of the ortho effect and the consequent base weakening.

Usha John et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60(10), 2337-2341 (2004-07-14)

The near infrared vibrational overtone absorption spectrum of liquid phase 2,6-dimethylaniline and 2,4-dimethylaniline are reported in the region deltanu = 2, 3 and 4. The aryl CH, methyl CH and NH local mode mechanical frequency values obtained from fitting the

Screening of specific inhibitors for human carboxylesterases or arylacetamide deacetylase.

Mai Shimizu et al.

Drug metabolism and disposition: the biological fate of chemicals, 42(7), 1103-1109 (2014-04-23)

Esterases catalyze the hydrolysis of therapeutic drugs containing esters or amides in their structures. Human carboxylesterase (CES) and arylacetamide deacetylase (AADAC) are the major enzymes that catalyze the hydrolysis of drugs in the liver. Characterization of the enzyme(s) responsible for

Metabolic activation of 2,6-xylidine in the nasal olfactory mucosa and the mucosa of the upper alimentary and respiratory tracts in rats.

Eva Tydén et al.

Toxicological sciences : an official journal of the Society of Toxicology, 81(2), 263-272 (2004-07-16)

Whole-body low-temperature radioluminography of (3)H-2,6-xylidine in rats indicates that the nonmetabolized substance, which is a volatile and fat-soluble compound, is distributed throughout the body and accumulates in adipose tissues, e.g., in the abdominal and subcutaneous regions. Whole-body autoradiography with freeze-dried

Analysis of the lidocaine metabolite 2,6-dimethylaniline in bovine and human milk.

N W Puente et al.

Journal of analytical toxicology, 25(8), 711-715 (2002-01-05)

2,6-Dimethylaniline (2,6-xylidine; 2,6-DMA) is a nasal carcinogen in rats. Humans may be exposed to this compound via several routes: 2,6-DMA is found in cigarette smoke; it is a pharmacologically inactive metabolite of some drugs (e.g., the local anesthetic lidocaine) and

Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography--electrospray ionization tandem mass spectrometry.

Robert J Strife et al.

Journal of chromatography. A, 1216(41), 6970-6973 (2009-09-08)

The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will help in identifying the environmental sources of such exposures. The separation of all six

Kinetics of 2,6-dimethylaniline degradation by electro-Fenton process.

Wang-Ping Ting et al.

Journal of hazardous materials, 161(2-3), 1484-1490 (2008-06-17)

A new approach for promoting ferric reduction efficiency using a different electrochemical cell and the photoelectro-Fenton process has been developed to degrade organic toxic contaminants. The use of UVA light and electric current as electron donors can efficiently initiate the

Kinetics and mechanism of 2,6-dimethyl-aniline degradation by hydroxyl radicals.

Nonglak Boonrattanakij et al.

Journal of hazardous materials, 172(2-3), 952-957 (2009-08-21)

This research investigated the intrinsic second-order rate constant between 2,6-dimethyl-aniline (2,6-DMA) and hydroxyl radicals (OH) using Fenton's reactions under both batch and continuous operations. The competitive kinetics technique with aniline as a reference compound was employed. In the batch study

The effect of deuterium and fluorine substitution upon the mutagenicity of N-hydroxy-2,6-dimethylaniline.

M Matilde Marques et al.

Mutation research, 506-507, 41-48 (2002-09-28)

2,6-Dimethylaniline (2,6-DMA) is an intermediate in the manufacture of several products, including pesticides, dyestuffs, and synthetic resins. It is also present in nanogram amounts in tobacco smoke, and is a major metabolite of the potent anesthetic and antiarrhythmic drug lidocaine

Assessment of the medicines lidocaine, prilocaine, and their metabolites, 2,6-dimethylaniline and 2-methylaniline, for DNA adduct formation in rat tissues.

Jian-Dong Duan et al.

Drug metabolism and disposition: the biological fate of chemicals, 36(8), 1470-1475 (2008-05-21)

The local anesthetics lidocaine (lido) and prilocaine (prilo) are metabolized to their constituent aromatic amines 2,6-dimethylaniline (DMA, 2,6-xylidine) and 2-methylaniline (MA, o-toluidine), respectively, which are both tumorigenic in rats. The capacity of lido and prilo to form DNA adducts was

2,6-Dimethylaniline (2,6-xylidine).

IARC monographs on the evaluation of carcinogenic risks to humans, 57, 323-335 (1993-01-01)

Temperature investigations of E/Z isomers in ketimines based of p-dibenzoylobenzene with aniline and 2,6-dimethylaniline by infrared spectroscopy.

Bozena Kaczmarczyk et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 68(2), 369-376 (2007-03-03)

The reaction of aniline with p-dibenzoylobenzene (K1) can lead to Z/Z, Z/E and E/E isomers however the only Z/Z and E/E were formed. At room temperature these isomers may be separated, thus the corresponding FTIR spectra could be recorded. The

Determination of 2,6-dimethylaniline and o-toluidine impurities in preparations for local anaesthesia by the HPLC method with amperometric detection.

Emil Baczyński et al.

Acta poloniae pharmaceutica, 59(5), 333-339 (2003-02-27)

2,6-Dimethylaniline (2,6-DMA) and o-toluidine (o-TLD) together with their decomposition products are potential technological impurities of Pharmaceuticals used for local anaesthesia, in which lidocaine and prilocaine appear as active substances. Pharmacopoeial analytical methods for the determination of these impurities are little

Kinetics of 2,6-dimethylaniline oxidation by various Fenton processes.

Nalinrut Masomboon et al.

Journal of hazardous materials, 192(1), 347-353 (2011-06-08)

The kinetics of 2,6-dimethylaniline degradation by Fenton process, electro-Fenton process and photoelectro-Fenton process was investigated. This study attempted to eliminate the potential interferences from intermediates by making a kinetics comparison of Fenton, electro-Fenton and photoelectro-Fenton methods through use initial rate

Genotoxicity of 2,6- and 3,5-dimethylaniline in cultured mammalian cells: the role of reactive oxygen species.

Ming-Wei Chao et al.

Toxicological sciences : an official journal of the Society of Toxicology, 130(1), 48-59 (2012-07-27)

Several alkylanilines with structures more complex than toluidines have been associated epidemiologically with human cancer. Their mechanism of action remains largely undetermined, and there is no reported evidence that it replicates that of multicyclic aromatic amines even though the principal

Changes in production of lignin degrading enzymes during interactions between mycelia of the tropical decomposer basidiomycetes Marasmiellus troyanus and Marasmius pallescens.

Ana P Ferreira Gregorio et al.

Mycological research, 110(Pt 2), 161-168 (2006-02-21)

During the interaction of two tropical agaric fungi, Marasmius pallescens and Marasmiellus troyanus, on agar media, initial deadlock between the two mycelia was ultimately followed by take-over by M. troyanus. When shaken liquid cultures of these two fungi were mixed

Synthesis, structure and pharmacology of acyl-2,6-xylidines.

Włodzimierz Białasiewicz et al.

Acta poloniae pharmaceutica, 61(3), 215-221 (2004-10-16)

L-2-perhydroheterocyclicalkyl acids were condensed with 2,6-xylidine. 8 new optically active acyl-2,6-xylidines were obtained. Absolute configuration of acyl-2,6-xylidines were selected for pharmacological examinations.

DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice.

Paul L Skipper et al.

Chemical research in toxicology, 19(8), 1086-1090 (2006-08-22)

Aromatic amines such as 2-naphthylamine and 4-aminobiphenyl are established human bladder carcinogens. Experimental evidence for carcinogenicity of monocylic aromatic amines is limited mostly to other organs, but a recent epidemiologic study of bladder cancer found that 2,6-dimethyl- (2,6-DMA), 3,5-dimethyl- (3,5-DMA)

Pharmacokinetics of xylazine, 2,6-dimethylaniline, and tolazoline in tissues from yearling cattle and milk from mature dairy cows after sedation with xylazine hydrochloride and reversal with tolazoline hydrochloride.

Todd M Delehant et al.

Veterinary therapeutics : research in applied veterinary medicine, 4(2), 128-134 (2003-09-25)

Xylazine hydrochloride was administered i.m. at 0.35 mg/kg to 13 steers and 10 lactating dairy cows at Time 0. Ten minutes later, tolazoline hydrochloride was given i.v. at 4 mg/kg. Tissue and milk samples were analyzed using gas chromatography with

Iron-catalyzed dehydrogenative phosphonation of N,N-dimethylanilines.

Wei Han et al.

Chemical communications (Cambridge, England), (40)(40), 6023-6025 (2009-10-08)

Iron(II) and iron(III) salts catalyze the oxidative alpha-phosphonation of N,N-dimethylanilines with dialkyl H-phosphonates in the presence of tert-butylhydroperoxide.

Lack of DNA binding in the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline.

Alan M Jeffrey et al.

Drug and chemical toxicology, 25(1), 93-107 (2002-02-20)

The phosphodiesterase 4 inhibitor Roflumilast (B9302-107) (RF) and its metabolite 4-amino-3,5-dichloropyridine (ADCP) produced nasal toxicity in preclinical safety studies with rats. The purpose of this study was to assess the possible formation of DNA adducts, by RF and ADCP, in

Retention time prediction of compounds in Grob standard mixture for apolar capillary columns in temperature-programmed gas chromatography.

Yasar Thewalim et al.

Analytical and bioanalytical chemistry, 393(1), 327-334 (2008-08-30)

This paper presents an extension of a previous investigation in which the behavior of nonpolar compounds in temperature-programmed gas chromatographic runs was predicted using thermodynamic (entropy and enthalpy) parameters derived from isothermal runs. In a similar manner, entropy and enthalpy

Third-order nonlinear optical properties and structures of (E)-N-(4-nitrobenzylidene)-2,6-dimethylaniline and (E)-N-(4-nitrobenzylidene)-2,3-dimethylaniline.

Asli Karakas et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75(5), 1492-1496 (2010-03-03)

(E)-N-(4-Nitrobenzylidene)-2,6-dimethylaniline (1) and (E)-N-(4-nitrobenzylidene)-2,3-dimethylaniline (2) have been synthesized. The crystal structures of both compounds have been defined by X-ray diffraction analysis. The maximum one-photon absorption (OPA) wavelengths recorded by quantum mechanical computations using a configuration interaction (CI) method are estimated

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