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Showing 1-30 of 77 results for "383112" within Papers
Takuro Isoda et al.
Clinical nuclear medicine, 39(8), 680-684 (2014-07-01)
Many cases of unexpected radioiodine uptake have been reported, including physiological uptake in healthy tissue and in both benign and malignant nonthyroidal lesions. However, iodine uptake in the uterus has not been well assessed. In this article, we systemically analyzed
Hanno Schieferstein et al.
Bioorganic & medicinal chemistry, 23(3), 612-623 (2014-12-30)
In this study we synthesized four different (18)F-labeling precursors for the visualization of the monoamino oxidase A using harmol derivatives. Whereas two are for prosthetic group labeling using [(18)F]fluoro-d2-methyl tosylate and 2-[(18)F]fluoroethyl-tosylate, the other three precursors are for direct nucleophilic
Hee-Jeong Jang et al.
Journal of the American Chemical Society, 136(50), 17674-17680 (2014-11-21)
Surface plasmonics of nanomaterials has been one of the main research themes in nanoscience. Spherical and elongated nanoparticles show their corresponding unique optical features mainly depending on the physical dimensions. Here we successfully synthesized Au nanorings having Pt framework (Pt@Au
Caroline Serrano-Nascimento et al.
Molecular and cellular endocrinology, 349(2), 154-161 (2011-10-18)
Iodide excess acutely downregulates NIS mRNA expression, as already demonstrated. PCCl3 cells treated or not with NaI, NaI+NaClO(4) or NaI+Methimazole, for 30 min to 24 h, were used to further explore how iodide reduces NIS gene expression. NIS mRNA expression
Giselle Grace Fernando Lim et al.
The protein journal, 31(7), 609-614 (2012-08-14)
Polyphenol oxidase (PPO) is a ubiquitous enzyme important in the food industry. Although PPO activity followed Michaelis-Menten kinetics at catechol concentrations of up to 1 mM, it slowly decreased at catechol concentrations above 2 mM. This result indicated that in
Charles A Pickering et al.
Health physics, 107(2 Suppl 2), S163-S165 (2014-06-21)
Initial radiation exposure levels X (0) at 1 m from the navel of thyroid cancer patients were measured for 165 individuals at the time of ingestion. Some 61 patients had previously signed informed consent so only those patients could be
Marlein Miranda Cona et al.
International journal of oncology, 44(3), 819-829 (2013-12-25)
Iodine-131‑labeled monoiodohypericin (131I‑Hyp) is a necrosis avid compound used as a complementary anticancer agent. Herein, the biodistribution in rats with re-perfused partial liver infarction (RPLI) was used to estimate its human internal radiation dosimetry. Iodine-123‑labeled monoiodohypericin (123I-Hyp) as a safer
Poly(propyleneimine) Dendrimers as pH-Sensitive Controlled-Release Systems.
Pistolis G, et al.
Chemistry (Weinheim An Der Bergstrasse, Germany), 5(5), 1440-1444 (1999)
Mohamed Touati et al.
Leukemia & lymphoma, 56(2), 332-341 (2014-04-29)
Finding new prognostic factors to identify patients with Hodgkin lymphoma (HL) at risk of treatment resistance or relapse remains challenging in daily practice. We evaluated the relationship between CD68 expression, interim positron emission tomography (iPET) results and outcome in 158
Christina Haberhauer-Troyer et al.
Analytical and bioanalytical chemistry, 405(6), 2031-2039 (2012-12-25)
A novel method for the simultaneous quantification of both glutathione (GSH) and its oxidized form glutathione disulfide (GSSG) by hydrophilic interaction chromatography-MS/MS has been developed and is critically discussed. Internal standardization based on isotopically labeled standards for both analytes is
Fabien Hyafil et al.
Molecular imaging, 14, 433-442 (2015-10-04)
[18F]ML-10 (2-(5-fluoro-pentyl)-2-methylmalonic acid) is a positron emission tomography (PET) radiotracer that accumulates in cells presenting apoptosis-specific membrane alterations. The aim of this study was to test whether [18F]ML-10 allows for the detection of apoptotic cells located in atherosclerotic plaques in
Astrid Subrizi et al.
Pharmaceutical research, 32(1), 211-221 (2014-07-18)
To measure the cytoprotective effects of rhHsp70 against oxidative stress and study its cellular uptake, intracellular and intraocular distribution in the retinal pigment epithelium. Human retinal pigment epithelial cells (ARPE-19) were pre-treated with rhHsp70 for 24 h, 48 h, and 72 h before
Hao Lou et al.
Pharmaceutical development and technology, 19(5), 548-555 (2013-06-15)
The purpose of this study is to evaluate the influence of sodium iodide, sodium chloride and sodium sulfate on the formation efficiency of sulfamerazine nanocrystals by wet ball milling. Sulfamerazine was milled using zirconium oxide beads in a solution containing
Tanya Q Shang et al.
Journal of pharmaceutical sciences, 103(7), 1967-1978 (2014-05-21)
A highly robust hydrophilic interaction liquid chromatography (HILIC) method that involves both fluorescence and mass spectrometric detection was developed for profiling and characterizing enzymatically released and 2-aminobenzamide (2-AB)-derivatized mAb N-glycans. Online HILIC/mass spectrometry (MS) with a quadrupole time-of-flight mass spectrometer
Björn Cohrs et al.
International journal of pharmaceutics, 477(1-2), 167-175 (2014-12-03)
Pentamidine is an effective antiparasitic agent and approved drug for the treatment of African trypanosomiasis (sleeping sickness). However, pentamidine suffers from poor orally bioavailability and lacks central nervous system (CNS) delivery. Therefore its applicability is limited to intravenous or intramuscular
Dafu Yu et al.
Hormones and behavior, 69, 106-115 (2015-01-28)
Thyroid hormone disorders have long been linked to depression, but the causal relationship between them remains controversial. To address this question, we established rat models of hypothyroidism using (131)iodine ((131)I) and hyperthyroidism using levothyroxine (LT4). Serum free thyroxine (FT4) and
Annukka M Kallinen et al.
Molecular pharmaceutics, 11(8), 2876-2886 (2014-07-01)
The use of nanoparticle carriers for the sustained release of cytotoxic drugs in cancer therapy can result in fewer adverse effects and can thus be of great benefit for the patient. Recently, a novel nanocomposite, prepared by the encapsulation of
Hooi Chuan Chin et al.
Archives of biochemistry and biophysics, 535(2), 241-247 (2013-05-07)
Solute transport through extracellular matrix (ECM) is important to physiology and contrast agent-based clinical imaging of articular cartilage. Mechanical injury is likely to have important effects on solute transport since it involves alteration of ECM structure. Therefore it is of
Fumie Sebe et al.
Physical chemistry chemical physics : PCCP, 14(13), 4433-4439 (2012-02-24)
Our earlier thermodynamic studies suggested that F(-) and Cl(-) form hydration shells with the hydration number 14 ± 2 and 2.3 ± 0.6, respectively, and leave the bulk H(2)O away from hydration shells unperturbed. Br(-) and I(-), on the other
J Bento et al.
Radiation protection dosimetry, 151(2), 252-261 (2012-02-22)
This work aims at assessing the performance of a portable detection system, equipped with an NaI(Tl) scintillation detector for in vivo thyroid monitoring, which was properly calibrated using an anthropomorphic neck phantom. The anthropomorphic physical phantoms commonly used for the
[How does iodine reach the thyroid gland? Recent studies of the sodium-iodide symporter].
J Köhrle et al.
Der Internist, 39(6), 560-565 (1998-07-25)
Evelien Wynendaele et al.
PloS one, 10(11), e0142071-e0142071 (2015-11-05)
Bacteria communicate with each other by the use of signaling molecules, a process called 'quorum sensing'. One group of quorum sensing molecules includes the oligopeptides, which are mainly produced by Gram-positive bacteria. Recently, these quorum sensing peptides were found to
Ada Repetto-Llamazares et al.
Anticancer research, 34(7), 3263-3269 (2014-07-02)
We herein report a comparison of the radiolabels 177Lu and 125I bound to the monoclonal antibody HH1 that targets the CD37 antigen expressed on non-Hodgkin B-cell lymphomas. Mixtures of 177Lu and 125I-labeled HH1 antibody were co-injected into nude mice carrying
Yu-Cheng Su et al.
Molecular cancer therapeutics, 13(12), 2852-2863 (2014-10-04)
Beta-glucuronidase (βG) is a potential biomarker for cancer diagnosis and prodrug therapy. The ability to image βG activity in patients would assist in personalized glucuronide prodrug cancer therapy. However, whole-body imaging of βG activity for medical usage is not yet
Young So et al.
Oncology reports, 29(4), 1666-1670 (2013-02-14)
Gene therapy using human sodium iodide symporter (hNIS) and radioiodine has been considered promising in a variety of gene therapy trials. However, the optimal timing of radioiodine application following hNIS gene transfer remains unknown. The present study aimed to investigate
Nardine S Abadeer et al.
ACS nano, 8(8), 8392-8406 (2014-07-26)
Plasmonic nanoparticles can strongly interact with adjacent fluorophores, resulting in plasmon-enhanced fluorescence or fluorescence quenching. This dipolar coupling is dependent upon nanoparticle composition, distance between the fluorophore and the plasmonic surface, the transition dipole orientation, and the degree of spectral
J W Scuffham et al.
The British journal of radiology, 85(1012), e76-e78 (2012-03-30)
An 80-year-old male with recurrent thyroid cancer and a percutaneous endoscopic gastrostomy (PEG) tube in situ was referred for radioiodine therapy and was administered 5510 MBq I-131 sodium iodide intravenously. Sequential whole-body images taken over the subsequent 7 days for
Angel T Chan et al.
Biomaterials, 73, 1-11 (2015-09-18)
Cell death due to anoikis, necrosis and cell egress from transplantation sites limits functional benefits of cellular cardiomyoplasty. Cell dissociation and suspension, which are a pre-requisite for most cell transplantation studies, lead to depression of cellular metabolism and anoikis, which
Aiwen Huang et al.
Drug delivery, 21(5), 388-396 (2013-11-06)
In this study both N-trimethyl chitosan chloride (TMC) and oligoarginine (Arg8) were utilized to modify liposomes as the multifunctional carriers (TMC-Arg8-Lips) for enhancing the oral absorption of salmon calcitonin. Two permeation enhancers with positive charges were sequentially adsorbed on the
Lan-Tao Li et al.
Chemical communications (Cambridge, England), 48(42), 5187-5189 (2012-04-20)
nBu(4)NI-catalyzed C3-selective formylation of N-H and N-substituted indoles by using N-methylaniline as a formylating reagent was first successfully demonstrated.
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