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Showing 1-30 of 132 results for "39319" within Papers
Pinakin Sukthankar et al.
Biochimica et biophysica acta, 1838(9), 2296-2305 (2014-02-26)
Branched amphiphilic peptide capsules (BAPCs) are peptide nano-spheres comprised of equimolar proportions of two branched peptide sequences bis(FLIVI)-K-KKKK and bis(FLIVIGSII)-K-KKKK that self-assemble to form bilayer delimited capsules. In two recent publications we described the lipid analogous characteristics of our BAPCs
Leila Lo Leggio et al.
Nature communications, 6, 5961-5961 (2015-01-23)
Lytic polysaccharide monooxygenases (LPMOs) are recently discovered enzymes that oxidatively deconstruct polysaccharides. LPMOs are fundamental in the effective utilization of these substrates by bacteria and fungi; moreover, the enzymes have significant industrial importance. We report here the activity, spectroscopy and
Jincheng Li et al.
Journal of mass spectrometry : JMS, 47(5), 620-626 (2012-05-12)
A new strategy was explored to generate pure gold cluster ions, Au(n)(+/-), from gold films deposited on solid substrates via a matrix-assisted laser ablation technique. The gold films deposited on SiO(2)-particle-assembled photonic crystals were demonstrated to be the most ideal
Tino Jaschinski et al.
Rapid communications in mass spectrometry : RCM, 28(13), 1521-1529 (2014-05-28)
Laser desorption ionization for mass spectrometric measurements (LDI MS) is supported by nanostructured materials. This technique helps to overcome known limitations of matrix-assisted laser desorption/ionization (MALDI) and especially avoids interfering signals caused by matrix components. LDI can be supported by
J H Liu et al.
Journal of chromatography. B, Biomedical applications, 675(1), 61-70 (1996-01-12)
A method for the simultaneous direct determination of salicylate (SA), its labile, reactive metabolite, salicyl acyl glucuronide (SAG), and two other major metabolites, salicyluric acid and gentisic acid in plasma and urine is described. Isocratic reversed-phase high performance liquid chromatography
Hana Paulova et al.
General physiology and biophysics, 32(2), 221-228 (2013-05-18)
Ischemic and reperfusion injury is a serious condition related to numerous biochemical and electrical abnormalities of the myocardium. It has been repeatedly studied in various animal models. In this study, the production of hydroxyl radicals and electrophysiological parameters were compared
M L Castillo-García et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 85-90 (2015-02-11)
A new method based on ultra high performance liquid chromatography (UPLC) with photometric and fluorometric detection for the determination of acetylsalicylic acid and its main metabolites, namely gentisic, salicylic and salicyluric acids, in bovine urine samples is reported. Photometric detection
Yin-Hung Lai et al.
The journal of physical chemistry. B, 116(32), 9635-9643 (2012-07-18)
This investigation concerns the initial chemical reactions that affect the ionization of matrixes in matrix-assisted laser desorption/ionization (MALDI). The study focuses on the relaxations of photon energy that occur on a comparable time scale to that of ionization, in which
Kinya Iwatsuka et al.
Current eye research, 39(7), 686-694 (2014-01-10)
We compared cultured Statens Seruminstitut rabbit cornea (SIRC) cells and corneal epithelial cells from rabbit eyes by analyzing their N-glycans and glycosaminoglycans (GAGs). This work is a fundamental study on the efficacy of using cultured cells instead of animals for
Vladimir V Egorov et al.
Prion, 8(5), 369-373 (2015-01-01)
The fibrillogenesis of a peptide corresponding to residues 35-51 of human α-lactalbumin (¹GYDTQAIVENNESTEYG¹⁷) can be dramatically enhanced by the addition of a tetrapeptide TDYG homologous to its C-terminus (TEYG). Generation of spontaneous hydrolytic products similar to this peptide was demonstrated
Sudha Ananth et al.
Biochimica et biophysica acta, 1842(4), 603-612 (2014-01-28)
Hypercholesterolemia and polymorphisms in the cholesterol exporter ABCA1 are linked to age-related macular degeneration (AMD). Excessive iron in retina also has a link to AMD pathogenesis. Whether these findings mean a biological/molecular connection between iron and cholesterol is not known.
Tammar Hussein Ali et al.
Colloids and surfaces. B, Biointerfaces, 123, 981-985 (2014-12-04)
A series of sugar-based surfactants, involving a single hydrophobic chain (C12) and two side-by-side arranged head groups, was prepared form simple glucose precursors. All surfactants were highly water soluble and exhibited exclusively micellar assemblies. This behavior makes them interesting candidates
Nozomi Takai et al.
Bioanalysis, 5(5), 603-612 (2013-02-22)
Therapeutic peptides and proteins are being increasingly explored as potential therapeutic agents for molecular-targeted therapy, and the requirement for quantitative bioanalytical tools for such molecules has been discussed. The distribution of octreotide, a synthetic octapeptide analog of somatostatin, in the
Guodong Fang et al.
Bioresource technology, 176, 210-217 (2014-12-03)
This paper investigated hydroxyl radical (OH) generation from biochar suspensions for diethyl phthalate (DEP) degradation in the presence of oxygen. Electron paramagnetic resonance (EPR) coupled with a salicylic acid trapping method were used to detect free radicals in biochar and
Emilie Bana et al.
Molecular carcinogenesis, 54(3), 229-241 (2013-10-25)
Cell division cycle (CDC) 25 proteins are key phosphatases regulating cell cycle transition and proliferation by regulating CDK/cyclin complexes. Overexpression of these enzymes is frequently observed in cancer and is related to aggressiveness, high-grade tumors and poor prognosis. Thus, targeting
Mariana Camargo et al.
Lipids, 49(9), 943-956 (2014-06-18)
This study proposed lipid fingerprinting of human seminal plasma by mass spectrometry as an analytical method to differentiate biological conditions. For this purpose, we chose infertile men as a model to study specific conditions, namely: high and low seminal plasma
Caroline Barrère et al.
Rapid communications in mass spectrometry : RCM, 26(11), 1347-1354 (2012-05-05)
Polyamides (PA) belong to the most used classes of polymers because of their attractive chemical and mechanical properties. In order to monitor original PA design, it is essential to develop analytical methods for the characterization of these compounds that are
Najla AlMasoud et al.
Analytica chimica acta, 840, 49-57 (2014-08-05)
Over the past few decades there has been an increased interest in using various analytical techniques for detecting and identifying microorganisms. More recently there has been an explosion in the application of matrix assisted laser desorption ionization time of flight
Radka Míková et al.
PloS one, 9(6), e99173-e99173 (2014-06-10)
Vernix caseosa protects the skin of a human fetus during the last trimester of pregnancy and of a newborn after the delivery. Besides its cellular and proteinaceous components, an important constituent and functional agent is a complex lipid fraction, implicated
G Palumbo et al.
Journal of pharmaceutical and biomedical analysis, 14(1-2), 175-180 (1995-12-01)
A high-performance liquid chromatographic method for the simultaneous determination of 5-aminosalicylic acid (5-ASA), acetyl-5-aminosalicylic acid (Ac-5-ASA) and 2,5-dihydroxybenzoic acid (5-HSA) in human endoscopic intestinal biopsy with electrochemical detection has been developed and validated. A liquid-liquid extraction procedure was used to
Jianhui Zhu et al.
Journal of proteome research, 13(6), 2986-2997 (2014-05-09)
We have developed herein a quantitative mass spectrometry-based approach to analyze the etiology-related alterations in fucosylation degree of serum haptoglobin in patients with liver cirrhosis and hepatocellular carcinoma (HCC). The three most common etiologies, including infection with hepatitis B virus
Dan Zhang et al.
Proteomics. Clinical applications, 14(1), e1900016-e1900016 (2019-11-11)
The authors aimed to separate Fc N-glycopeptides of disease-specific immunoglobulin G (DSIgG) as personalized biomarkers to distinguish non-small cell lung cancer (NSCLC) from benign lung diseases (BLDs). DSIgG from 509 BLDs patients and 477 NSCLC patients was isolated using native
S A Ponomarenko et al.
Faraday discussions, 174, 313-339 (2014-10-04)
This contribution describes recent progress in the design, synthesis and properties of solution-processible star-shaped oligomers and their application in organic photovoltaics. Even though alternative chemistry has been used to design such oligomers, the most successful approach is based on a
Thomas Eickner et al.
European journal of mass spectrometry (Chichester, England), 17(5), 507-523 (2011-12-17)
There have been many successful efforts to enrich phosphopeptides in complex protein mixtures by the use of immobilized metal affinity chromatography (IMAC) and/or metal oxide affinity chromatography (MOAC) with which mass spectrometric analysis of phosphopeptides has become state of the
M Grootveld et al.
The Biochemical journal, 237(2), 499-504 (1986-07-15)
Attack by .OH radicals, generated by a Fenton system, upon salicylate produces 2,3-dihydroxybenzoate and 2,5-dihydroxybenzoate as major products and catechol as a minor product. H.p.l.c. separation combined with electrochemical detection was used to identify and quantify 2,3-dihydroxybenzoate and 2,5-dihydroxybenzoate in
Lei Zhou et al.
Carbohydrate research, 402, 180-188 (2014-12-17)
C-type lectin-like receptor 2 (CLEC-2) is a newly identified receptor expressed on the platelet surface. It has been reported that CLEC-2 exists as a higher molecular weight (HMW) and a lower molecular weight (LMW) form, which share the same protein
J N Buskin et al.
Clinical chemistry, 28(5), 1200-1203 (1982-05-01)
Detailed performance specifications are given for a specific and sensitive liquid-chromatographic assay for aspirin, salicylic acid, and salicyluric acid in plasma. The sensitivity of this method for aspirin (50 micrograms/L) is 10-fold that of previous methods, so that concentrations of
Yu-Shu Huang et al.
Food chemistry, 174, 571-576 (2014-12-23)
Curcumin is the major active ingredient of turmeric and is widely used as a preservative, flavouring and colouring agent. Curcumin is a potent substance with several functions, including antioxidant, antitumor, anti-inflammatory, antimicrobial, antiparasitic, antimutagenic, chemopreventive and chemotherapeutic activities. Matrix-assisted laser
Yann Bernhard et al.
Dalton transactions (Cambridge, England : 2003), 44(7), 3200-3208 (2015-01-13)
Subphthalocyanine (SubPc), a putative fluorophore for optical imaging (OI), was conjugated to chelating ligands (DOTA, DTPA) affording water-soluble conjugates complexed with (non-radioactive) metals relevant to the following medical imaging techniques/therapies: MRI (Gd), PET (Cu, Ga), SPECT (In, Ga, Lu), RIT
Zhuoming Liu et al.
Molecular and cellular biology, 34(13), 2533-2546 (2014-04-30)
Eukaryotes produce a siderophore-like molecule via a remarkably conserved biosynthetic pathway. 3-OH butyrate dehydrogenase (BDH2), a member of the short-chain dehydrogenase (SDR) family of reductases, catalyzes a rate-limiting step in the biogenesis of the mammalian siderophore 2,5-dihydroxybenzoic acid (2,5-DHBA). Depletion
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