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Showing 31-60 of 132 results for "39319" within Papers
Mandana Hunter et al.
Journal of neurochemistry, 146(5), 613-630 (2018-05-29)
The human subventricular zone (SVZ) has a defined cytological and neurochemical architecture, with four constituent laminae that act in concert to support its neurogenic activity. Lipidomic specialisation has previously been demonstrated in the neurologically normal human SVZ, with enrichment of
Elodie Alinat et al.
Journal of chromatography. A, 1387, 134-143 (2015-02-24)
Fine characterization of nitrocellulose (NC) remains a challenge, especially in forensic analysis, and a strategy consisting in obtaining representative fingerprints by a separation technique, as for proteins, is of prime interest. In this work, we first established that NCs (especially
Ericka N Pompa-Mera et al.
Research in veterinary science, 97(3), 533-545 (2014-10-15)
The development of a veterinary vaccine against T. spiralis infection is an alternative strategy to control trichinellosis. In an effort to develop an efficient vaccine, BALB/c mice were immunized with attenuated Salmonella enterica serovar Typhimurium SL3261 that expresses a 30-mer
Michal Afri et al.
Chemistry and physics of lipids, 184, 119-128 (2014-07-30)
In our companion paper, we described the preparation and intercalation of two homologous series of dicarbonyl compounds, methyl n-oxooctadecanoates and the corresponding n-oxooctadecanoic acids (n=4-16), into DMPC liposomes. (13)C NMR chemical shift of the various carbonyls was analyzed using an
Voin Petrović et al.
Journal of inorganic biochemistry, 140, 228-235 (2014-09-01)
Na(+)/K(+)-ATPase is in charge of maintaining the ionic and osmotic intracellular balance by using ATP as an energy source to drive excess Na(+) ions out of the cell in exchange for K(+) ions. We explored whether three representative cytotoxic gold(III)
Wei Zhang-Sun et al.
FEBS letters, 589(1), 165-171 (2014-12-06)
The levels of sulfate-reducing bacteria (SRB), including Desulfovibrionaceae, in the gut increase following a fat-enriched diet. Endotoxins from gut microbiota contribute to the inflammation process, leading to metabolic diseases. Thus, we sought to characterize the lipid A structures of Desulfovibrionaceae
Mysore S Hemalatha et al.
Journal of the science of food and agriculture, 92(4), 764-771 (2011-09-29)
Chapati preparation involves various processing steps such as mixing the flour into dough, sheeting and baking. During these processing steps, flour components are likely to undergo changes in their nutrient and polyphenol composition and their antioxidant properties due to phenol-mediated
Mengzhe Guo et al.
Analytica chimica acta, 865, 31-38 (2015-03-04)
Matrix-assisted laser desorption ionization (MALDI) time-of-flight mass spectrometry (TOF-MS) can be considered as state of the art in the field of proteins and peptides analysis. In this work, we have designed an ionic liquid derivative strategy to obtain abundant fragment
Issey Osaka et al.
Rapid communications in mass spectrometry : RCM, 27(1), 103-108 (2012-12-15)
Although matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) is an important method for post-translational modification (PTM) analysis, the conventional matrices, 2,5-dihydroxybenzoic acid (2,5-DHB) and 1,5-diaminonaphthalene (1,5-DAN), are poor in terms of the fragment ion yields of the phosphorylated peptides. The use
Genggeng Qi et al.
Nature communications, 5, 5796-5796 (2014-12-17)
Adsorption using solid amine sorbents is an attractive emerging technology for energy-efficient carbon capture. Current syntheses for solid amine sorbents mainly based on physical impregnation or grafting-to methods (for example, aminosilane-grafting) lead to limited sorbent performance in terms of stability
B E Cham et al.
Clinical chemistry, 26(1), 111-114 (1980-01-01)
We have developed a specific and sensitive method for the determination of salicylic acid, salicyluric acid, and gentisic acid in urine. Any proteins present are precipitated with methyl cyanide. After centrifugation, an aliquot of the supernate is directly injected into
Thomas Hauch Fenger et al.
Chembiochem : a European journal of chemical biology, 16(4), 575-583 (2015-02-11)
A series of N-bromoacetylglycosylamines and bromoketone C-glycosides were synthesised from complex xyloglucan oligosaccharide (XyGO) scaffolds as specific active-site affinity labels for endo-xyloglucanases. Compounds based on XXXG (Xyl3 Glc4 ) and XLLG (Xyl3 Glc4 Gal2 ) oligosaccharides exhibited strikingly higher affinities
Colin Correnti et al.
PloS one, 7(8), e43696-e43696 (2012-08-29)
Siderocalin (also lipocalin 2, NGAL or 24p3) binds iron as complexes with specific siderophores, which are low molecular weight, ferric ion-specific chelators. In innate immunity, siderocalin slows the growth of infecting bacteria by sequestering bacterial ferric siderophores. Siderocalin also binds
Kewei Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14807-14812 (2013-08-21)
The plant hormone salicylic acid (SA) plays critical roles in plant defense, stress responses, and senescence. Although SA biosynthesis is well understood, the pathways by which SA is catabolized remain elusive. Here we report the identification and characterization of an
Daiki Asakawa et al.
Journal of the American Society for Mass Spectrometry, 24(2), 297-300 (2013-01-12)
MALDI in-source decay (ISD) has been used for top-down sequencing of proteins. The use of the matrix 1,5-diaminonapthalene (1,5-DAN) gave abundant w ions, which are formed from the unimolecular dissociation of z• radical fragments via α cleavage reaction and thus
Gabriella Pinto et al.
Journal of chromatography. A, 1360, 82-92 (2014-08-26)
The comprehensive analysis of natural lipid mixtures is often challenging due to the simultaneous occurrence of functionally and structurally heterogeneous compounds. Modern analytical approaches in system-wide lipidomics essentially rely on mass spectrometry (MS). The overabundant amount of triacylglycerols (TAGs) in
Marialetizia Motta et al.
Human molecular genetics, 23(21), 5814-5826 (2014-06-14)
Saposin (Sap) C is an essential cofactor for the lysosomal degradation of glucosylceramide (GC) by glucosylceramidase (GCase) and its functional impairment underlies a rare variant form of Gaucher disease (GD). Sap C promotes rearrangement of lipid organization in lysosomal membranes
Lakshmi Dhevi N Selvan et al.
Journal of proteomics, 97, 287-295 (2013-07-16)
Cryptococcus neoformans is an encapsulated pathogenic yeast, which causes life threatening meningitis in immunocompromised individuals. C. neoformans var. grubii is the most prevalent and virulent form among the two varieties of C. neoformans - C. neoformans var. grubii and C.
Rasha H Alghamdi et al.
European journal of medicinal chemistry, 92, 890-907 (2015-02-14)
High level of Low Density Lipoprotein-Cholesterol (LDL-C) in circulation in the blood is associated with an elevated risk of cardiovascular disease (CVD) and stroke. Currently the statin drugs which inhibit the enzyme HMG-CoA reductase responsible for cholesterol synthesis in the
Dhaka Ram Bhandari et al.
Analytical and bioanalytical chemistry, 407(8), 2189-2201 (2014-11-27)
Mass spectrometry imaging provides for non-targeted, label-free chemical imaging. In this study, atmospheric pressure high-resolution scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging (AP-SMALDI MSI) was used for the first time to describe the chemical distribution of the defensive compounds
Viktoria Dotz et al.
Molecular nutrition & food research, 59(2), 355-364 (2014-10-21)
Various biological effects have been postulated for human milk oligosaccharides (HMO), as deduced from in vitro, animal, and epidemiological studies. Little is known about their metabolic fate in vivo in the breast-fed infant, which is presented here. Human milk and
Wei-Ting Hung et al.
Molecules (Basel, Switzerland), 17(5), 4950-4961 (2012-05-02)
MALDI-TOF MS provides rapid and sensitive analyses of larger biomolecules. However, MS analyses of polysaccharide have been reported to have lower sensitivity compared to peptides and proteins. Here, we investigated some polysaccharides chemically derivatized by permethylation and ortho-phenylene diamine (OPD)
Edyta Burda et al.
Nature communications, 5, 5170-5170 (2014-11-19)
Sensitive detection of small molecule fragments binding to defined sites of biomacromolecules is still a considerable challenge. Here we demonstrate that protein-binding fragments are able to induce enzymatic reactions on the protein surface via dynamic fragment ligation. Fragments binding to
J R Vergara-Salinas et al.
Food chemistry, 171, 62-69 (2014-10-14)
Pressurized hot water extracts obtained at different temperatures possess different compositions and antioxidant activities and, consequently, different bioactivities. We characterized two pressurized hot water extracts from grape pomace obtained at 100°C (GPE100) and 200°C (GPE200) in terms of antioxidant activity
Chunli Fang et al.
Analytica chimica acta, 841, 99-105 (2014-08-12)
Selective enrichment of glycopeptides prior to the mass spectrometry (MS) analysis is essential due to ion suppression effect during ionization caused by the co-presence of non-glycosylated peptides. Among the enrichment approaches, hydrophilic interaction liquid chromatography (HILIC) based on magnetic separation
Lei Zhang et al.
Talanta, 131, 632-639 (2014-10-05)
Metal nanoparticles (NPs) have recently attracted considerable attention in many areas of research including bioscience, chemistry and material science. Regrettably, most current and past work usually focuses on studies of multi-component NPs mixture where there is a plethora of NPs
Laura Sanchez-Lazo et al.
Molecular endocrinology (Baltimore, Md.), 28(9), 1502-1521 (2014-07-25)
Oocyte meiotic maturation requires energy from various substrates including glucose, amino acids, and lipids. Mitochondrial fatty acid (FA) β-oxidation (FAO) in the oocyte is required for meiotic maturation, which is accompanied by differential expression of numerous genes involved in FAs
Brett Fleisher et al.
Journal of pharmaceutical sciences, 104(1), 266-275 (2014-11-25)
Small molecule tyrosine kinase inhibitors (TKIs) are a group of highly novel and target-specific anticancer drugs. Recently, most TKIs are found to be substrates of P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). However, little information is available regarding the
Bernard Quéméner et al.
Journal of mass spectrometry : JMS, 50(1), 247-264 (2015-01-21)
Xyloglucans of apple, tomato, bilberry and tamarind were hydrolyzed by commercial endo β-1-4-D-endoglucanase. The xylo-gluco-oligosaccharides (XylGos) released were separated on CarboPac PA 200 column in less than 15 min, and, after purification, they were structurally characterized by negative electrospray ionization mass
Li-Ting Liao et al.
Clinica chimica acta; international journal of clinical chemistry, 436, 72-77 (2014-05-13)
Uric acid measurement has become increasingly important, and electrochemically modified detection method based portable devices hold a dominant position in the market for point of care and self-monitoring of uric acid blood levels. However, there has been a lack of
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