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Showing 1-30 of 107 results for "409286" within Papers
Natsuhiko Sugimura et al.
European journal of mass spectrometry (Chichester, England), 21(2), 91-96 (2015-07-17)
To provide a practical guideline for the selection of a mass spectrometer ion source, we compared the applicability of three types of ion source: direct analysis in real time (DART), electrospray ionization (ESI) and fast atom bombardment (FAB), using an
Neeta Pandit-Taskar et al.
EJNMMI research, 5, 28-28 (2015-05-20)
J591 is a monoclonal antibody that targets the external domain of the prostate-specific membrane antigen (PSMA). Besides prostate cancer cells, it also targets the neovasculature of non-prostate solid tumors. We provide an analysis of the antibody mass-dose dependency of lesion
Małgorzata Wolny et al.
Endokrynologia Polska, 58(6), 512-521 (2008-01-22)
The sodium iodide symporter, called also the NIS protein is responsible for iodine trapping to the cell what is significant for the thyroid function. Identified and described for the first time in 1996 NIS protein is the matter of interest
Nan Zhang et al.
Pharmaceutical research, 31(9), 2326-2334 (2014-03-07)
To evaluate the therapeutic efficacy of dexamethasone (DM) and methotrexate (MTX) entrapped within polysialic acid (PSA)-trimethyl chitosan (TMC) nanoparticles using an in vitro model of rheumatoid arthritis (RA). The loading capacity of the PSA-TMC nanoparticles was determined. An RA in
Anna Ohradanova et al.
Bioorganic & medicinal chemistry letters, 22(3), 1314-1316 (2012-01-10)
An α-carbonic anhydrase (CA, EC 4.2.1.1) isolated from the living fossil sponge Astrosclera willeyana, Astrosclerin, was investigated for its inhibition profile with simple inorganic anions, complex anions and other small molecules known to interact with these zinc enzymes. Astrosclerin is
M Rasoulinejad et al.
Radiation protection dosimetry, 151(3), 580-585 (2012-03-22)
A couple of 2-inch by 2-inch right cylinder sodium iodide scintillators and an Am-Be radioisotope neutron source have been used in a neutron porosity well-logging tool to explore the variation of hydrogen contents in a prototype formation. Both Monte Carlo
Prakash Ramalingam et al.
Pharmaceutical research, 32(2), 389-402 (2014-08-02)
Solid lipid nanoparticles (SLNs) have been proposed as a colloidal carrier system that could enhance the oral bioavailability of curcumin. However, a burst release of the loaded drug, which occurs in acidic environments, has been a main obstacle to the
Amita Datta-Mannan et al.
mAbs, 7(3), 483-493 (2015-02-20)
Lowering the isoelectric point (pI) through engineering the variable region or framework of an IgG can improve its exposure and half-life via a reduction in clearance mediated through non-specific interactions. As such, net charge is a potentially important property to
Zi-Ming Zhao et al.
Chemical & pharmaceutical bulletin, 63(3), 180-186 (2015-03-12)
Two types of amphoteric calix[n]arene carboxylic acid (CnCA) derivative, i.e., calix[6]arene hexa-carboxylic acid (C6HCA) and calix[8]arene octo-carboxylic acid (C8OCA), were synthesized by introducing acetoxyls into the hydroxyls of calix[n]arene (n=6, 8). C6HCA and C8OCA nanoparticles (NPs) were prepared successfully using
Timothy D Kayes et al.
Cellular immunology, 285(1-2), 84-91 (2013-10-19)
IFN-γ(-/-) NOD.H-2h4 mice develop a spontaneous autoimmune thyroid disease, thyroid epithelial cell hyperplasia and proliferation (TEC H/P) when given NaI in their water for 7+ mo. TEC H/P can be transferred to IFN-γ(-/-) SCID mice by splenocytes from mice with
Yayoi S Kikkawa et al.
Journal of translational medicine, 12, 280-280 (2014-10-05)
A cochlear implant (CI) is an artificial hearing device that can replace a damaged cochlea. The present study examined the use of growth factor-eluting gelatin hydrogel coatings on the electrodes to minimize inner ear trauma during electrode insertion. Insulin-like growth
E Gordon DePuey et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 19(5), 931-944 (2012-07-11)
A stress (S)/rest (R) 1-day Tc-99m sestamibi protocol is logistically advantageous and facilitates stress-only imaging. However, with conventional 370 MBq (10 mCi) S activity and subsequent 1,110-1,295 MBq (30-35 mCi) R activity there is a risk of S-to-R "shine-through" and
Karin Schilbach et al.
Oncoimmunology, 4(7), e1014760-e1014760 (2015-07-04)
Stimulating the immune system to attack cancer is a promising approach, even for the control of advanced cancers. Several cytokines that promote interferon-γ-dominated immune responses show antitumor activity, with interleukin 12 (IL-12) being of major importance. Here, we used an
Zachary C Kennedy et al.
Langmuir : the ACS journal of surfaces and colloids, 31(46), 12742-12752 (2015-10-27)
The interactions of nanoparticles with biomolecules, surfaces, or other nanostructures are dictated by the nanoparticle's surface chemistry. Thus, far, shortcomings of syntheses of nanoparticles with defined ligand shell architectures have limited our ability to understand how changes in their surface
Ningna Li et al.
The British journal of nutrition, 107(5), 674-682 (2011-07-29)
Our previous epidemiological study indicated that excessive intake of iodine could potentially lead to hypothyroidism. In the present study, we aimed to investigate the time and dose effect of iodine intake on serum thyrotropin (thyroid-stimulating hormone, TSH) levels and to
Camila Lopes Cardoso et al.
Acta cirurgica brasileira, 26(5), 365-372 (2011-09-29)
To evaluate two treatment modalities of dry socket in rats and to discuss the first findings of the molecular analysis in this experimental model. 84 rats underwent a tooth extraction were divided in 4 groups: I-uninfected socket (control), II-infected socket
Jose A Castro-Osma et al.
Dalton transactions (Cambridge, England : 2003), 44(27), 12388-12400 (2014-12-24)
A series of alkyl organoaluminium complexes based on bulky heteroscorpionate ligands were designed as catalysts for the ring-opening polymerisation of cyclic esters. Thus, the treatment of AlX3 (X = Me, Et) with bulky acetamide or thioacetamide heteroscorpionate ligands nbptamH (1)
John Metyko et al.
Health physics, 103(5 Suppl 3), S204-S208 (2012-10-17)
Yittrium-90 microsphere brachytherapy procedures have increased in number due to their efficacy in treating some unresectable metastatic liver tumors. The discovery of long-lived impurities in two microsphere products, first reported between 2006 and 2007, has resulted in some radiation safety
Alessandra Cincinelli et al.
Bioorganic & medicinal chemistry, 19(6), 1847-1851 (2011-03-08)
A high activity α-carbonic anhydrase (CA, EC 4.2.1.1) has been purified from various tissues of the Antarctic seal Leptonychotes weddellii. The new enzyme, denominated lwCA, has a catalytic activity for the physiologic CO(2) hydration to bicarbonate reaction, similar to that
Angela Lombardi et al.
The Journal of clinical endocrinology and metabolism, 100(1), E1-10 (2014-10-09)
Amiodarone (AMIO) is one of the most effective antiarrhythmic drugs available; however, its use is limited by a serious side effect profile, including thyroiditis. The mechanisms underlying AMIO thyroid toxicity have been elusive; thus, identification of novel approaches in order
Alexander David Ardianrama et al.
Journal of colloid and interface science, 552, 485-493 (2019-06-04)
Although triangular silver (Ag) nanoplates are intrinsically unstable, this characteristic has been taken advantage of in the development of a novel sensing platform. However, most of these applications have relied on halide ions as etchants. In the current work, we
Caroline Barrère et al.
Rapid communications in mass spectrometry : RCM, 26(11), 1347-1354 (2012-05-05)
Polyamides (PA) belong to the most used classes of polymers because of their attractive chemical and mechanical properties. In order to monitor original PA design, it is essential to develop analytical methods for the characterization of these compounds that are
Anke de Vries et al.
Investigative radiology, 50(4), 297-304 (2015-01-01)
The objective of this study was to investigate the feasibility and the accuracy of spectral computed tomography (spectral CT) to determine the tissue concentrations and localization of high-attenuation, iodine-based contrast agents in mice. Iodine tissue concentrations determined with spectral CT
Itaru Sato et al.
Animal science journal = Nihon chikusan Gakkaiho, 86(7), 716-720 (2014-12-17)
Radioactivity inspection of slaughtered cattle is generally conducted using a portion of the neck muscle; however, there is limited information about the distribution of radioactive cesium in cattle. In this study, therefore, we measured not only radioactive cesium but also
Zhibo Liu et al.
Molecular pharmaceutics, 12(3), 974-982 (2015-01-30)
Bradykinin B1 receptor (B1R) is involved in pain and inflammation pathways and is upregulated in inflamed tissues and cancer. Due to its minimal expression in healthy tissues, B1R is an attractive target for the development of therapeutic agents to treat
Jason S Ellis et al.
Journal of immunology (Baltimore, Md. : 1950), 191(10), 4940-4949 (2013-10-08)
NOD.H-2h4 mice given NaI in their drinking water develop iodine-accelerated spontaneous autoimmune thyroiditis (ISAT) with chronic inflammation of the thyroid by T and B cells and production of anti-mouse thyroglobulin (MTg) autoantibody. CD28(-/-) NOD.H-2h4 mice, which have reduced numbers of
Abu T Khan et al.
Carbohydrate research, 346(16), 2629-2632 (2011-10-11)
A wide variety of dithioacetal derivatives of sugars can be cleaved easily into the corresponding open-chain aldehydo sugars using an efficient combination of VO(acac)(2)/H(2)O(2)/NaI at 0-5°C. Some of the salient features of this protocol are mild reaction conditions, good yields
R Glenn Wells et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(5), 764-770 (2015-04-05)
Rotenone derivatives have shown promise in myocardial perfusion imaging (MPI). CMICE-013 is a novel (123)I-labeled rotenone derivative developed for SPECT MPI. The objective of this study was to assess the image quality of CMICE-013 and compare its uptake with tetrofosmin
Suyitno Suyitno et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 148, 99-104 (2015-04-16)
The present article reports on the enhancement of the performance and stability of natural dye-based dye-sensitized solar cells (DSSCs). Natural dyes extracted from papaya leaves (PL) were investigated as sensitizers in TiO2-based DSSCs and evaluated in comparison with N719 dye.
M E Manley et al.
Scientific reports, 1, 4-4 (2012-02-23)
Intrinsic localized modes (ILMs) - also known as discrete breathers - are localized excitations that form without structural defects in discrete nonlinear lattices. For crystals in thermal equilibrium ILMs were proposed to form randomly, an idea used to interpret temperature
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