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Showing 1-30 of 52 results for "45684" within Papers
Lakshminarayana Polavarapu et al.
Small (Weinheim an der Bergstrasse, Germany), 10(15), 3065-3071 (2014-05-03)
The translation of a technology from the laboratory into the real world should meet the demand of economic viability and operational simplicity. Inspired by recent advances in conductive ink pens for electronic devices on paper, we present a "pen-on-paper" approach
Damien Stark et al.
Parasite (Paris, France), 21, 41-41 (2014-08-26)
Recently, Dientamoeba fragilis has emerged as a significant and common enteropathogen. The majority of patients with dientamoebiasis present with gastrointestinal complaints and chronic symptoms are common. Numerous studies have successfully demonstrated parasite clearance, coupled with complete resolution of clinical symptoms
Aya Shohat-Tal et al.
Eukaryotic cell, 10(12), 1705-1713 (2011-11-01)
The integrity of mitosis is dependent upon strict regulation of microtubule stability and dynamics. Although much information has been accumulated on regulators of the microtubule cytoskeleton, our knowledge of the specific pathways involved is still limited. Here we designed genetic
Zeno Bisoffi et al.
PLoS neglected tropical diseases, 5(7), e1254-e1254 (2011-08-05)
Strongyloidiasis may cause a life-threatening disease in immunosuppressed patients. This can only be prevented by effective cure of chronic infections. Direct parasitologic exams are not sensitive enough to prove cure if negative. We used an indirect immune fluorescent antibody test
Kevin C Gough et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 46(7), 581-589 (2011-07-07)
This paper describes the isolation of monoclonal antibodies and the development of competitive immunoassays to pesticide metabolites of the fungicides imazalil, carbendazim and thiabendazole. The metabolite specific hydroxyl residues were used as the reactive group with which to link the
Yuko Imamura et al.
The FEBS journal, 281(20), 4612-4621 (2014-08-13)
3,6-Epidioxy-1,10-bisaboladiene (EDBD), a bisabolane sesquiterpene endoperoxide compound, was previously isolated from Cacalia delphiniifolia and C. hastata in northern Japan. EDBD has cytotoxic effects and induces apoptosis via phosphorylation of p38 mitogen-activated protein kinase in human promyelocytic leukemia HL60 cells. However
Anastasios A Malandrakis et al.
International journal of food microbiology, 162(3), 237-244 (2013-03-05)
Penicillium expansum field-strains resistant to benzimidazole fungicides were isolated in high frequency from decayed apple fruit collected from packinghouses and processing industries located in the region of Imathia, N. Greece. In vitro fungitoxicity tests resulted in the identification of two
Esther Turiel et al.
Journal of separation science, 35(21), 2962-2969 (2012-10-16)
Stir-bar sorptive extraction is based on the partitioning of target analytes between the sample (mostly aqueous-based liquid samples) and a stationary phase-coated magnetic stir bar. Until now, only PDMS-coated stir bars are commercially available, restricting the range of applications to
John L Stebbins et al.
Journal of medicinal chemistry, 50(26), 6607-6617 (2007-11-28)
Peptidyl-prolyl cis-trans isomerases are a group of cytosolic enzymes initially characterized by their ability to catalyze the cis-trans isomerization of peptidyl-prolyl bonds. This represents a significant event for protein folding because cis-proline introduces critical bends within the protein conformation. FK506-binding
C Calvete et al.
Veterinary parasitology, 203(1-2), 102-113 (2014-04-08)
The egg hatch assay (EHA) is one of the main in vitro methods for detection of benzimidazole resistance in nematode parasites of small ruminants. However, although the EHA has been standardised at the laboratory level, the diagnostic performance of this
Salvatore D'Aquino et al.
Food chemistry, 141(2), 858-864 (2013-06-26)
Postharvest treatments of potassium sorbate only controlled recently established infections of Penicillium digitatum on Femminello siracusano lemons but did not confer any persistent protection. The loss of efficacy of potassium sorbate to control green mould decay was related to its
Andrew C Kotze et al.
PLoS neglected tropical diseases, 5(6), e1203-e1203 (2011-07-09)
Current efforts to control human soil-transmitted helminths (STHs) involve the periodic mass administration of benzimidazole drugs to school aged children and other at- risk groups. Given that high levels of resistance to these drugs have developed in roundworms of livestock
Cutaneous manifestations of Strongyloides stercoralis hyperinfection in an HIV-seropositive patient.
Stephanie J Martin et al.
Skinmed, 9(3), 199-202 (2011-06-17)
A 41-year-old human immunodeficiency virus (HIV)-positive man was hospitalized with complaints of a 4-week history of nausea and vomiting, associated with decreased oral intake, and a 4-day history of frontal headache and fever. His medical history was significant for a
Santosh Soparawalla et al.
The Analyst, 136(21), 4392-4396 (2011-09-06)
We describe a rapid in situ method for detecting agrochemicals on the surface or in the tissue of fruit using a portable mass spectrometer equipped with an ambient ionization source. Two such ionization methods, low temperature plasma (LTP) and paper
Zdena Malá et al.
Electrophoresis, 34(5), 777-784 (2012-12-12)
In this contribution we present an innovative way to easy, fast, and highly sensitive analyses by CE with ESI-MS detection. The new method is designed to be applied to ESI-compatible electrolytes (e.g. ammonium acetate) and offers advanced tuning of selectivity
Rolf Schiffmann et al.
Journal of medicinal chemistry, 49(2), 511-522 (2006-01-20)
We report the discovery of thiabendazole as a potent inhibitor (K(i) = 0.4 microM) of Escherichia coli methionine aminopeptidase (ecMetAP) and the synthesis and pharmacological evaluation of thiabendazole congeners with activity in the upper nanomolar range. Elucidation of the X-ray
Matthieu Groh et al.
Clinical and experimental rheumatology, 30(1 Suppl 70), S107-S109 (2012-07-26)
Polyarteritis nodosa (PAN), a systemic necrotising vasculitis that affects medium- and small-sized arteries, has visceral involvement in 40-60% of the patients. According to the Five-Factor Score (FFS), it is associated with poor outcome. We describe a patient who underwent orthotopic
M Soledade C Pedras et al.
Bioorganic & medicinal chemistry, 15(17), 5981-5996 (2007-06-26)
Sclerotinia sclerotiorum is a fungal pathogen, which causes stem rot in crucifer crops and in several other plant families resulting in enormous yield losses all over the world. Brassinin is a phytoalexin produced by crucifer plants as part of a
Xin-Juan Yang et al.
Molecules (Basel, Switzerland), 17(11), 13026-13035 (2012-11-06)
In order to understand the antifungal activity of some derivatives of sanguinarine (S) and chelerythrine (C) and their structure-activity relationships, sixteen derivatives of S and C were prepared and evaluated for in vitro antifungal activity against seven phytopathogenic fungi by
Pierre Ducray et al.
Bioorganic & medicinal chemistry letters, 18(9), 2935-2938 (2008-04-11)
A new series of amino-acetonitrile derivatives (AAD) have been discovered that exhibit high anthelmintic activity against parasitic nematode species such as Haemonchus contortus and Trichostrongylus colubriformis. Significantly, these compounds also demonstrate activity against nematode strains resistant to the currently available
Stuart Dashper et al.
Antimicrobial agents and chemotherapy, 54(3), 1311-1314 (2009-12-30)
Porphyromonas gingivalis is a major pathogen of chronic periodontitis and exists in a biofilm on the surface of the tooth root. Oxantel, a cholinergic anthelmintic and fumarate reductase inhibitor, significantly inhibited biofilm formation by P. gingivalis and disrupted established biofilms
Lourdes Santana et al.
Journal of medicinal chemistry, 51(21), 6740-6751 (2008-10-07)
The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives
Shinobu Ukimori et al.
Bioscience, biotechnology, and biochemistry, 76(2), 264-269 (2012-02-09)
In the fission yeast Schizosaccharomyces pombe, deletion of trt1(+) causes gradual telomere shortening, while deletion of pot1(+) causes rapid telomere loss. The double mutant between pot1 and RecQ helicase rqh1 is synthetically lethal. We found that the trt1 rqh1 double
The therapeutic efficacy of thiabendazole for helminthic infections in man; a literature review.
A C Cuckler et al.
Arzneimittel-Forschung, 16(3), 411-428 (1966-03-01)
Satoshi Kawashima et al.
The EMBO journal, 30(16), 3353-3367 (2011-07-21)
The attachment of sister kinetochores to microtubules from opposite spindle poles is essential for faithful chromosome segregation. Kinetochore assembly requires centromere-specific nucleosomes containing the histone H3 variant CenH3. However, the functional roles of the canonical histones (H2A, H2B, H3, and
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated
Nan Shang et al.
Wei sheng yan jiu = Journal of hygiene research, 40(3), 365-367 (2011-06-24)
To explore the distribution and elimination of thiabendazole and its metabolite 5-hydrothiabendazole residues in the hens tissues including liver, muscle, heart, fat, as well as in eggs. Laying hens were orally administred thiabendazole for 5 consecutive days (100mg per hen
Lili He et al.
Food chemistry, 148, 42-46 (2013-11-23)
We developed a rapid and simple method which combines a surface swab capture method and surface-enhanced Raman spectroscopy for recovery and quantitative detection of thiabendazole on apple surfaces. The whole apple surface was swabbed and the swab was vortexed in
Jinnan Zhang et al.
Die Pharmazie, 68(12), 962-968 (2014-01-10)
Thiabendazole, an orally available antifungal drug, has been used in clinical practice for 40 years. Previous studies indicated its potential in inhibiting angiogenesis in both animal models and in human cells. Malignant melanoma is associated with angiogenesis and it is
Rafael Igual-Adell et al.
Expert opinion on pharmacotherapy, 5(12), 2615-2619 (2004-12-02)
Treatment of strongyloidiasis has been traditionally based on thiabendazole, despite its frequent gastrointestinal side effects and failure to achieve eradication of the parasite from faeces in approximately 30% of cases. Ivermectin has been shown to be more effective for treating
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