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Showing 1-30 of 3635 results for "459844" within Papers
Sang Jin Kim et al.
ChemSusChem, 8(22), 3783-3792 (2015-10-21)
Herein, we report a high performance polymer membrane with simultaneously large improvements in the CO2 permeability and CO2/N2 selectivity. These improvements are obtained by incorporation of a multi-functional amphiphilic comb copolymer micelle, that is, poly(dimethylsiloxane)-g-poly(oxyethylene methacrylate) (PDMS-g-POEM), into a poly(amide-b-ethylene
Heloísa H P Oliveira et al.
Ecotoxicology and environmental safety, 122, 106-115 (2015-08-01)
The effects of benzo(a)pyrene (BaP), dichlorodiphenyltrichloroethane (DDT) and tributyltin (TBT) association were investigated through a multi-biomarker approach. Ten Rhamdia quelen fish per group were exposed through intraperitoneal injections either to BaP (0.3; 3 or 30 mg kg(-1)), DDT or TBT
Zachary Yu-Ching Lin et al.
Developmental biology, 400(1), 43-58 (2015-01-28)
Mammalian spermatogenesis has been investigated extensively in rodents and a strictly controlled developmental process has been defined at cellular and molecular levels. In comparison, primate spermatogenesis has been far less well characterized. However, important differences between primate and rodent spermatogenesis
Clemens Tscheka et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 95(Pt A), 151-155 (2015-03-18)
Cylindrical particles offer the opportunity to develop controlled and sustained release systems for the respiratory tract. One reason is that macrophages can phagocyte such particles only from either of the two ends. We investigated the uptake behaviour of murine alveolar
Maria A Agapito et al.
Endocrinology, 155(7), 2578-2588 (2014-05-07)
Early-life ethanol feeding (ELAF) alters the metabolic function of proopiomelanocortin (POMC)-producing neurons and the circadian expression of clock regulatory genes in the hypothalamus. We investigated whether the circadian mechanisms control the action of ELAF on metabolic signaling genes in POMC
Talent Chipiti et al.
Acta poloniae pharmaceutica, 72(1), 119-127 (2015-04-09)
The study was intended to explore the antioxidant potential and phytochemical content of the ethanol and aqueous extracts of the leaf and root samples of Cissus cornifolia (Baker) Splanch (Vitaceae) across a series of four in vitro models. The results
Yuhei Takado et al.
Journal of chemical neuroanatomy, 69, 7-12 (2015-09-27)
Glucose is the primary source of energy for the brain but also an important source of building blocks for proteins, lipids, and nucleic acids. Little is known about the use of glucose for biosynthesis in tissues at the cellular level.
Francesco Del Giudice et al.
Lab on a chip, 15(3), 783-792 (2014-12-02)
A novel method to estimate the relaxation time of viscoelastic fluids, down to milliseconds, is here proposed. The adopted technique is based on the particle migration phenomenon occurring when the suspending viscoelastic fluid flows in microfluidic channels. The method is
J N Gutiérrez-Rivera et al.
Diseases of aquatic organisms, 112(3), 185-197 (2015-01-16)
Proliferation of Perkinsus marinus (Dermo) in vitro is inhibited by the action of 2 serine protease inhibitors belonging to the I-84 family. We compared the levels of expression of serine protease inhibitors 1 and 2 (SPI-1 and SPI-2) in 2
Elisabetta Casarin et al.
Fitoterapia, 98, 241-247 (2014-08-12)
A different behavior of the two dibenzocyclooctadiene lignans (+)-deoxyschisandrin (1) and (-)-gomisin N (2), from Schisandra chinensis fruits, was observed against two human tumour cell lines, (2008 and LoVo). These lignans inhibited cell growth in a dose-dependent manner on both
Hamada AbdElgawad et al.
The New phytologist, 208(2), 354-369 (2015-06-04)
Proline (Pro) is a versatile metabolite playing a role in the protection of plants against environmental stresses. To gain a deeper understanding of the regulation of Pro metabolism under predicted future climate conditions, including drought stress, elevated temperature and CO2
Frithjof Lohmann et al.
Biochimica et biophysica acta, 1842(7), 945-958 (2014-03-04)
Podocytes are terminally differentiated cells of the glomerular filtration barrier that react with hypertrophy in the course of injury such as in membranous nephropathy (MGN). The neuronal deubiquitinase ubiquitin C-terminal hydrolase L1 (UCH-L1) is expressed and activated in podocytes of
Shannon M Clarke et al.
PloS one, 9(4), e93392-e93392 (2014-04-18)
Accurate pedigree information is critical to animal breeding systems to ensure the highest rate of genetic gain and management of inbreeding. The abundance of available genomic data, together with development of high throughput genotyping platforms, means that single nucleotide polymorphisms
Ana Belen Lopez-Rodriguez et al.
Cerebral cortex (New York, N.Y. : 1991), 25(1), 35-45 (2013-08-21)
Traumatic brain injury (TBI) and its consequences represent one of the leading causes of death in young adults. This lesion mediates glial activation and the release of harmful molecules and causes brain edema, axonal injury, and functional impairment. Since glial
Miglė Graužinytė et al.
Angewandte Chemie (International ed. in English), 54(5), 1456-1460 (2014-12-10)
Millimeter-scale tubes are observed to sprout from water droplets injected into a bath of toluene containing ethanol and silica colloids. This phenomenon requires that first a membrane is formed by the colloids which self-assemble at the droplet interface, and second
Rong Gao et al.
Applied and environmental microbiology, 81(23), 7993-8007 (2015-09-13)
Burkholderia glumae PG1 is a soil-associated motile plant-pathogenic bacterium possessing a cell density-dependent regulation system called quorum sensing (QS). Its genome contains three genes, here designated bgaI1 to bgaI3, encoding distinct autoinducer-1 (AI-1) synthases, which are capable of synthesizing QS
Karpagavalli Ramji et al.
Journal of biomaterials applications, 29(3), 411-422 (2014-04-09)
Electrospun fibers with an average fiber diameter in the nanometer range were prepared from soy protein isolate to develop scaffolds for tissue engineering applications. Poly(ethylene oxide) was added to facilitate fiber formation. The influence of processing parameters such as applied
Luka Mihajlovic et al.
Phytochemistry, 109, 125-132 (2014-12-04)
Phenolic composition of Ambrosia artemisiifolia L. pollen and sub-pollen particles (SPP) aqueous extracts was determined, using a novel extraction procedure. Total phenolic and flavonoid content was determined, as well as the antioxidative properties of the extract. Main components of water-soluble
Emily E Noble et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(6), R737-R745 (2014-07-06)
Central oxytocin reduces food intake and increases energy expenditure. The ventromedial hypothalamic nucleus (VMN) is associated with energy balance and contains a high density of oxytocin receptors. We hypothesized that oxytocin in the VMN is a negative regulator of energy
Qiaozhen Yu et al.
Journal of biomedical materials research. Part A, 103(2), 721-729 (2014-05-16)
An axially aligned three-dimensional (3-D) fibrous scaffold was fabricated with regenerated spider silk protein (RSSP)/poly (l-lactic acid) (PLLA) through electrospinning and post treatment. The morphology, mechanical and degradation properties of the scaffold were controlled through the weight ratio of RSSP
Huiping Zhang et al.
Human genetics, 133(11), 1383-1394 (2014-07-31)
Chronic alcohol consumption may induce gene expression alterations in brain reward regions such as the prefrontal cortex (PFC), modulating the risk of alcohol use disorders (AUDs). Transcriptome profiles of 23 AUD cases and 23 matched controls (16 pairs of males
Dafna Kanny et al.
MMWR. Morbidity and mortality weekly report, 63(53), 1238-1242 (2015-01-13)
Alcohol poisoning is typically caused by binge drinking at high intensity (i.e., consuming a very large amount of alcohol during an episode of binge drinking). Approximately 38 million U.S. adults report binge drinking an average of four times per month
Jara Majuelos-Melguizo et al.
Oncotarget, 6(7), 4790-4803 (2015-01-13)
Glioblastoma multiforme (GBM) is the most common primary brain tumour in adults and one of the most aggressive cancers. PARP-1 is a nuclear protein involved in multiple facets of DNA repair and transcriptional regulation. In this study we dissected the
Jeongyub Kim et al.
Stem cells and development, 24(3), 284-295 (2014-09-18)
There is a growing body of evidence that small subpopulations of cells with stem cell-like characteristics within most solid tumors are responsible for the malignancy of aggressive cancer cells and that targeting these cells might be a good therapeutic strategy
Charles S Elmore et al.
Journal of labelled compounds & radiopharmaceuticals, 57(5), 342-349 (2014-04-05)
In support of a program to develop an alpha 7 agonist as a treatment for Alzheimer's disease, three drug candidates, 1, 2, and 3, were prepared in labeled forms. Compound 1 was prepared in C-14 labeled form by lithiation of
Shanshan Cheng et al.
The international journal of biochemistry & cell biology, 57, 186-196 (2014-12-03)
Impairment in the microRNA (miRNA) network causes a number of neurodegenerative diseases. Endoribonuclease Dicer is a key RNase to produce mature miRNAs. It has been shown that Dicer is important for the maintenance of excitatory neuron survival during early postnatal
William J Chapin et al.
Pharmacogenetics and genomics, 25(3), 126-133 (2015-01-08)
Despite of the common usage of glucocorticoids (GCs), a significant portion of asthma patients exhibit GC insensitivity. This could be mediated by diverse mechanisms, including genomics. Recent work has suggested that measuring changes in gene expression may provide more predictive
Kuo-Chin Huang et al.
BMC musculoskeletal disorders, 16, 355-355 (2015-11-18)
Prolonged bisphosphonate treatment might suppress bone remodeling to the extent that normal bone repair is impaired. While this adverse side effect is usually ascribed to the negative effects of bisphosphonates on osteoclast survival and function, these effects on osteoblasts are
Federico Colombo et al.
PloS one, 9(12), e114787-e114787 (2014-12-11)
Despite continuous improvements in therapeutic protocols, cancer-related mortality is still one of the main problems facing public health. The main cause of treatment failure is multi-drug resistance (MDR: simultaneous insensitivity to different anti-cancer agents), the underlying molecular and biological mechanisms
Malgorzata Kotula-Balak et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(3), 529-537 (2015-01-03)
Our previous studies revealed that in bank vole testicular cells octylphenol (OP) action is related either to its binding to estrogen receptors or increasing cAMP level that modulates spermatozoa motility and acrosome reaction (AR), (Kotula-Balak et al., 2011, 2014). To
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