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Showing 1-30 of 174 results for "47861" within Papers
Jeannette Beckman Rehnman et al.
JAMA ophthalmology, 132(12), 1426-1432 (2014-08-30)
A reliable tool for quantification of the biomechanical status of the cornea in conjunction with corneal collagen crosslinking (CXL) treatment is needed. To quantify the biomechanical effects of CXL in vivo. A prospective, open, case-control study was conducted at the
Amy L Olex et al.
Gene, 542(1), 38-45 (2014-03-19)
Osteoarthritis (OA) is characterized by remodeling and degradation of joint tissues. Microarray studies have led to a better understanding of the molecular changes that occur in tissues affected by conditions such as OA; however, such analyses are limited to the
Assaf Dotan et al.
Experimental eye research, 127, 190-195 (2014-08-12)
Our study demonstrates the effect of scleral cross-linking using riboflavin and ultraviolet-A radiation on the development of axial myopia in a rabbit model. Axial length of the eyeball was measured by A-scan ultrasound in 22 New Zealand white rabbits aged
Elodie Barbau-Piednoir et al.
BMC biotechnology, 15, 103-103 (2015-11-13)
Recently, the presence of an unauthorized genetically modified (GM) Bacillus subtilis bacterium overproducing vitamin B2 in a feed additive was notified by the Rapid Alert System for Food and Feed (RASFF). This has demonstrated that a contamination by a GM
Simone Langer et al.
Journal of bacteriology, 195(18), 4037-4045 (2013-07-10)
The riboflavin analog roseoflavin is an antibiotic produced by Streptomyces davawensis. Riboflavin transporters are responsible for roseoflavin uptake by target cells. Roseoflavin is converted to the flavin mononucleotide (FMN) analog roseoflavin mononucleotide (RoFMN) by flavokinase and to the flavin adenine
Leane Hoey et al.
The American journal of clinical nutrition, 89(6), 1960S-1980S (2009-05-01)
National survey data of erythrocyte glutathione reductase activation coefficient (EGRac) indicate that suboptimal riboflavin status may be a problem in all population age groups, but the cutoff for deficiency is controversial. In addition, the effectiveness of different biomarkers of riboflavin
Brian K Armstrong et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(5), 332-341 (2013-05-11)
To compare the biological effects of riboflavin-ultraviolet A (UVA) corneal cross-linking (CXL) performed with a traditional epithelium-off method to several transepithelial methods in a rabbit model. Preliminary experiments on biomechanical rigidity were also performed. Four treatment groups were included: (1)
S Keskin et al.
Journal of economic entomology, 106(2), 1058-1063 (2013-06-22)
The objective of this study was to evaluate how storage and Sitophilus granarius L. infestation affects mineral and vitamin (thiamin and riboflavin) contents of wheat grain and flour obtained from the wheat. Wheat samples were infested with nonsexed S. granarius
Alejandro Arboleda et al.
American journal of ophthalmology, 158(1), 64-70 (2014-05-06)
To compare the in vitro effect of rose bengal and riboflavin as photosensitizing agents for photodynamic therapy (PDT) on fungal isolates that are common causes of fungal keratitis. Experimental study. Three isolates (Fusarium solani, Aspergillus fumigatus, Candida albicans) recovered from
Olivier Richoz et al.
Investigative ophthalmology & visual science, 55(9), 5783-5787 (2014-07-24)
When treating peripheral ectatic disease-like pellucid marginal degeneration (PMD), corneal cross-linking with UV-A and riboflavin (CXL) must be applied eccentrically to the periphery of the lower cornea, partly irradiating the corneal limbus. Here, we investigated the effect of standard and
Maryam Goudarzi et al.
Radiation and environmental biophysics, 53(4), 645-657 (2014-07-23)
Metabolomics has been shown to have utility in assessing responses to exposure by ionizing radiation (IR) in easily accessible biofluids such as urine. Most studies to date from our laboratory and others have employed γ-irradiation at relatively high dose rates
Chien-Hsun Huang et al.
Molecules (Basel, Switzerland), 20(10), 17720-17734 (2015-09-26)
Melanoma is extremely resistant to chemotherapy and the death rate is increasing hastily worldwide. Extracellular matrix promotes the migration and invasion of tumor cells through the production of matrix metalloproteinase (MMP)-2 and -9. Evidence has shown that natural dietary antioxidants
Caterina Garone et al.
JAMA neurology, 70(9), 1177-1179 (2013-07-10)
Mendelian forms of complex I deficiency are usually associated with fatal infantile encephalomyopathy. Application of "MitoExome" sequencing (deep sequencing of the entire mitochondrial genome and the coding exons of >1000 nuclear genes encoding the mitochondrial proteome) allowed us to reveal
Yue Teng et al.
PloS one, 9(8), e106003-e106003 (2014-08-27)
2-Mercaptobenzimidazole (MBI) is widely utilized as a corrosion inhibitor, copper-plating brightener and rubber accelerator. The residue of MBI in the environment is potentially harmful. In the present work, the toxic interaction of MBI with the important antioxidant enzyme copper-zinc superoxide
Katsumi Shibata et al.
Bioscience, biotechnology, and biochemistry, 78(12), 2102-2109 (2014-08-15)
We previously reported that mild food restriction induces a reduction in tryptophan-nicotinamide conversion, which helps to explain why death secondary to pellagra is pandemic during the hungry season. In this study, we investigated the levels of B-group vitamins in the
M Hilal Sehitoglu et al.
Journal of enzyme inhibition and medicinal chemistry, 30(2), 264-269 (2014-06-19)
In the present study, in order to evaluate antioxidant and radical scavenging properties of Pistachio gum (P-Gum), different bioanalytical methods such as DPPH(•) scavenging activity, DMPD(•+) radical scavenging activity, total antioxidant activity determination by ferric thiocyanate, reducing ability Fe(3+)-Fe(2+) transformation
Achyut Mukherjee et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 253(12), 2223-2228 (2015-09-09)
This laboratory-based investigation compares the topographic outcomes of conventional penetrating keratoplasty with that of a novel procedure in which donor corneas are cross-linked prior to keratoplasty. Penetrating keratoplasty procedures with continuous running sutures were carried out in a porcine whole
Andrew L Garfoot et al.
Infection and immunity, 82(1), 393-404 (2013-11-06)
During infection of the mammalian host, Histoplasma capsulatum yeasts survive and reside within macrophages of the immune system. Whereas some intracellular pathogens escape into the host cytosol, Histoplasma yeasts remain within the macrophage phagosome. This intracellular Histoplasma-containing compartment imposes nutritional
Naomi L Kruhlak et al.
Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01)
ABSTRACT Drug-induced phospholipidosis (PL) is a condition characterized by the accumulation of phospholipids and drug in lysosomes, and is found in a variety of tissue types. PL is frequently manifested in preclinical studies and may delay or prevent the development
Vinay Agrawal
Indian journal of ophthalmology, 61(8), 433-434 (2013-08-09)
Corneal collagen cross-linking with riboflavin and UVA light (CXL) is the only method designed to arrest the progression of keratoconus. Visual improvement generally starts 3 months after treatment. Reduction is coma seen on aberrometry in early postoperative phase is also
Damon H May et al.
The British journal of nutrition, 110(10), 1760-1770 (2013-05-10)
Metabolomic profiles were used to characterise the effects of consuming a high-phytochemical diet compared with a diet devoid of fruits and vegetables (F&V) in a randomised trial and cross-sectional study. In the trial, 8 h fasting urine from healthy men
Hany S Elsaftawy et al.
Cornea, 34(11), 1420-1426 (2015-09-12)
To assess the clinical outcomes after sequential surgical implantation of intracorneal ring segments and transepithelial corneal collagen cross-linking (TE-CXL) in keratoconic eyes. In this consecutive randomized study, 40 eyes of 29 patients with progressive mild to moderate keratoconus were included
Anastasios John Kanellopoulos et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 28(11 Suppl), S837-S840 (2013-03-02)
To evaluate the safety and efficacy of intrastromally applied collagen cross-linking (CXL) in a comparative contralateral eye study of topography-guided femtosecond laser-assisted hyperopic LASIK. Thirty-four consecutive patients with hyperopia and hyperopic astigmatism elected to have bilateral topography-guided LASIK and were
Reply: To PMID 23347371.
Harsha Nagaraj et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(6), 377-377 (2013-07-03)
Rosalba Carrozzo et al.
Mitochondrion, 18, 49-57 (2014-09-25)
Dihydrolipoamide dehydrogenase (DLD, E3) is a flavoprotein common to pyruvate, α-ketoglutarate and branched-chain α-keto acid dehydrogenases. We found two novel DLD mutations (p.I40Lfs*4; p.G461E) in a 19 year-old patient with lactic acidosis and a complex amino- and organic aciduria consistent
Tobias Gräwert et al.
IUBMB life, 65(4), 310-322 (2013-03-05)
GTP cyclohydrolases generate the first committed intermediates for the biosynthesis of certain vitamins/cofactors (folic acid, riboflavin, deazaflavin, and tetrahydrobiopterin), deazapurine antibiotics, some t-RNA bases (queuosine, archaeosine), and the phytotoxin, toxoflavin. They depend on divalent cations for hydrolytic opening of the
M Nebbioso et al.
European review for medical and pharmacological sciences, 17(8), 1117-1122 (2013-05-11)
Chronic use of multi-dose eye drops containing preservatives, such as it may happen in patients affected by primary open angle glaucoma, often results in a damage of the ocular surface due to the inherent toxicity of preservatives, that with time
Despoina Theofylaktopoulou et al.
The British journal of nutrition, 112(7), 1065-1072 (2014-08-12)
Vitamins B2 and B6 are cofactors in the kynurenine pathway. Many of the kynurenines are neuroactive compounds with immunomodulatory effects. In the present study, we aimed to investigate plasma concentrations of vitamins B2 and B6 as determinants of kynurenines and
Ambreen Hafeez et al.
Pakistan journal of pharmaceutical sciences, 26(3), 487-493 (2013-04-30)
Riboflavin (vitamin B2) belongs to a group of respiratory enzymes that occur widely in animals and plants participating in vital oxidation- reduction processes in the body. A computational study was conducted on riboflavin by ArgusLab 4.0.1 to obtain the most
Andre A M Torricelli et al.
Experimental eye research, 125, 114-117 (2014-06-15)
Studies suggest that standard corneal collagen crosslinking (CXL) is a safe and effective treatment to stiffen the cornea for keratoconus and other ectatic corneal disorders. The purpose of the present study was to compare the biomechanical effects of transepithelial benzalkonium
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