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Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development.

Neville Young et al.

Journal of the National Cancer Institute, 98(15), 1060-1067 (2006-08-03)

The growth of solid tumors depends on establishing blood supply; thus, inhibiting tumor angiogenesis has been a long-term goal in cancer therapy. The SOX18 transcription factor is a key regulator of murine and human blood vessel formation. We established allograft

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