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Showing 1-30 of 6342 results for "493511" within Papers
H Yang et al.
Cell death & disease, 6, e1786-e1786 (2015-06-13)
High-mobility group box 1 (HMGB1) is an inflammatory molecule that has a critical role in the initiation and progression of malignant mesothelioma (MM). Aspirin (acetylsalicylic acid, ASA) is the most widely used nonsteroidal anti-inflammatory drug that reduces the incidence, metastatic
Christina M Birch et al.
Scientific reports, 5, 11347-11347 (2015-07-02)
Plasmodium falciparum malaria parasites invade and remodel human red blood cells (RBCs) by trafficking parasite-synthesized proteins to the RBC surface. While these proteins mediate interactions with host cells that contribute to disease pathogenesis, the infected RBC surface proteome remains poorly
M Plaza-Oliver et al.
International journal of pharmaceutics, 490(1-2), 209-218 (2015-05-23)
Most frequently the use of bioactive molecules for the supplementation of food and beverages is hampered by stability limitations or inadequate intestinal absorption. This work evaluates in vitro the role that the interface of the nanoemulsion has on the physicochemical
Sang Jin Kim et al.
ChemSusChem, 8(22), 3783-3792 (2015-10-21)
Herein, we report a high performance polymer membrane with simultaneously large improvements in the CO2 permeability and CO2/N2 selectivity. These improvements are obtained by incorporation of a multi-functional amphiphilic comb copolymer micelle, that is, poly(dimethylsiloxane)-g-poly(oxyethylene methacrylate) (PDMS-g-POEM), into a poly(amide-b-ethylene
Jinyun Yu et al.
Parasitology research, 114(7), 2499-2505 (2015-04-17)
Caused by the consumption of raw or undercooked freshwater fish containing infective metacercariae of Clonorchis sinensis, human clonorchiasis remains a major public health problem in China. In previous study, we had expressed enolase from C. sinensis (CsENO) on the surface
Heloísa H P Oliveira et al.
Ecotoxicology and environmental safety, 122, 106-115 (2015-08-01)
The effects of benzo(a)pyrene (BaP), dichlorodiphenyltrichloroethane (DDT) and tributyltin (TBT) association were investigated through a multi-biomarker approach. Ten Rhamdia quelen fish per group were exposed through intraperitoneal injections either to BaP (0.3; 3 or 30 mg kg(-1)), DDT or TBT
Zachary Yu-Ching Lin et al.
Developmental biology, 400(1), 43-58 (2015-01-28)
Mammalian spermatogenesis has been investigated extensively in rodents and a strictly controlled developmental process has been defined at cellular and molecular levels. In comparison, primate spermatogenesis has been far less well characterized. However, important differences between primate and rodent spermatogenesis
Clemens Tscheka et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 95(Pt A), 151-155 (2015-03-18)
Cylindrical particles offer the opportunity to develop controlled and sustained release systems for the respiratory tract. One reason is that macrophages can phagocyte such particles only from either of the two ends. We investigated the uptake behaviour of murine alveolar
Maria A Agapito et al.
Endocrinology, 155(7), 2578-2588 (2014-05-07)
Early-life ethanol feeding (ELAF) alters the metabolic function of proopiomelanocortin (POMC)-producing neurons and the circadian expression of clock regulatory genes in the hypothalamus. We investigated whether the circadian mechanisms control the action of ELAF on metabolic signaling genes in POMC
Talent Chipiti et al.
Acta poloniae pharmaceutica, 72(1), 119-127 (2015-04-09)
The study was intended to explore the antioxidant potential and phytochemical content of the ethanol and aqueous extracts of the leaf and root samples of Cissus cornifolia (Baker) Splanch (Vitaceae) across a series of four in vitro models. The results
Yuhei Takado et al.
Journal of chemical neuroanatomy, 69, 7-12 (2015-09-27)
Glucose is the primary source of energy for the brain but also an important source of building blocks for proteins, lipids, and nucleic acids. Little is known about the use of glucose for biosynthesis in tissues at the cellular level.
Francesco Del Giudice et al.
Lab on a chip, 15(3), 783-792 (2014-12-02)
A novel method to estimate the relaxation time of viscoelastic fluids, down to milliseconds, is here proposed. The adopted technique is based on the particle migration phenomenon occurring when the suspending viscoelastic fluid flows in microfluidic channels. The method is
Jong-Pyo Kang et al.
Antonie van Leeuwenhoek, 108(3), 619-626 (2015-07-01)
A novel bacterial strain DCY104(T) isolated from soil of a ginseng field in Yeoncheon County, Republic of Korea is described in this study. Cells were short rod-shaped, motile by mean of one polar flagellum, strictly aerobic, Gramreaction negative, oxidase and
Mads Harsløf et al.
Journal of neuroscience methods, 253, 101-109 (2015-06-17)
Biocytin has found numerous uses as a neuronal tracer, since it shows both antero- and retrograde transport in neuronal tracts. The main advantage of biocytin lies in the comprehensive intracellular distribution of the molecule, and in effective detection using avidin-based
J N Gutiérrez-Rivera et al.
Diseases of aquatic organisms, 112(3), 185-197 (2015-01-16)
Proliferation of Perkinsus marinus (Dermo) in vitro is inhibited by the action of 2 serine protease inhibitors belonging to the I-84 family. We compared the levels of expression of serine protease inhibitors 1 and 2 (SPI-1 and SPI-2) in 2
Hongyu Chen et al.
Molecular pharmaceutics, 12(6), 1885-1892 (2015-04-15)
Monitoring of drugs in vivo has been recognized as an urgent need for successful chemotherapy treatment. However, to find an appropriate tool for this purpose has been proved as a great challenge. Here, we report a PLA-PEG coated hollow X-ray
H Zhao et al.
Journal of biological regulators and homeostatic agents, 29(2), 459-464 (2015-07-01)
Breast cancer tends to have an increasing mortality, severely threatening the health of females. The invasion and metastasis of breast cancer are the leading causes of death. It has been reported that breast cancer is caused by the activation of
Elisabetta Casarin et al.
Fitoterapia, 98, 241-247 (2014-08-12)
A different behavior of the two dibenzocyclooctadiene lignans (+)-deoxyschisandrin (1) and (-)-gomisin N (2), from Schisandra chinensis fruits, was observed against two human tumour cell lines, (2008 and LoVo). These lignans inhibited cell growth in a dose-dependent manner on both
Zachary Farrell et al.
Angewandte Chemie (International ed. in English), 54(22), 6479-6482 (2015-04-18)
MALDI mass-spectrometry measurements are combined with self-consistent mean-field (SCF) calculations to detect and predict ligand phase separation on Ag nanoparticles. The experimental and theoretical techniques complement each other by enabling quantification of the nearest-neighbor distribution of a ligand mixture in
Hamada AbdElgawad et al.
The New phytologist, 208(2), 354-369 (2015-06-04)
Proline (Pro) is a versatile metabolite playing a role in the protection of plants against environmental stresses. To gain a deeper understanding of the regulation of Pro metabolism under predicted future climate conditions, including drought stress, elevated temperature and CO2
Frithjof Lohmann et al.
Biochimica et biophysica acta, 1842(7), 945-958 (2014-03-04)
Podocytes are terminally differentiated cells of the glomerular filtration barrier that react with hypertrophy in the course of injury such as in membranous nephropathy (MGN). The neuronal deubiquitinase ubiquitin C-terminal hydrolase L1 (UCH-L1) is expressed and activated in podocytes of
Chao Hu et al.
World journal of gastroenterology, 21(19), 5884-5892 (2015-05-29)
To investigate the effect of microRNA-1 (miR-1) on tumor endothelial cells (TECs) of human hepatocellular carcinoma (HCC). MiR-1 specific short hairpin RNA (shRNA) was synthesized and cloned into a recombinant lentiviral vector. TECs were then infected by the miRNA-1-shRNA recombinant
Shannon M Clarke et al.
PloS one, 9(4), e93392-e93392 (2014-04-18)
Accurate pedigree information is critical to animal breeding systems to ensure the highest rate of genetic gain and management of inbreeding. The abundance of available genomic data, together with development of high throughput genotyping platforms, means that single nucleotide polymorphisms
Suyitno Suyitno et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 148, 99-104 (2015-04-16)
The present article reports on the enhancement of the performance and stability of natural dye-based dye-sensitized solar cells (DSSCs). Natural dyes extracted from papaya leaves (PL) were investigated as sensitizers in TiO2-based DSSCs and evaluated in comparison with N719 dye.
Prathap Kumar S Mahalingaiah et al.
Breast cancer research and treatment, 153(1), 41-56 (2015-07-26)
The role of chronic oxidative stress in the development and aggressive growth of estrogen receptor (ER)-positive breast cancer is well known; however, the mechanistic understanding is not clear. Estrogen-independent growth is one of the features of aggressive subtype of breast
Ana Belen Lopez-Rodriguez et al.
Cerebral cortex (New York, N.Y. : 1991), 25(1), 35-45 (2013-08-21)
Traumatic brain injury (TBI) and its consequences represent one of the leading causes of death in young adults. This lesion mediates glial activation and the release of harmful molecules and causes brain edema, axonal injury, and functional impairment. Since glial
Brian P Anton et al.
PloS one, 10(5), e0127446-e0127446 (2015-05-27)
We report the complete sequence of ER2796, a laboratory strain of Escherichia coli K-12 that is completely defective in DNA methylation. Because of its lack of any native methylation, it is extremely useful as a host into which heterologous DNA
Miglė Graužinytė et al.
Angewandte Chemie (International ed. in English), 54(5), 1456-1460 (2014-12-10)
Millimeter-scale tubes are observed to sprout from water droplets injected into a bath of toluene containing ethanol and silica colloids. This phenomenon requires that first a membrane is formed by the colloids which self-assemble at the droplet interface, and second
Rong Gao et al.
Applied and environmental microbiology, 81(23), 7993-8007 (2015-09-13)
Burkholderia glumae PG1 is a soil-associated motile plant-pathogenic bacterium possessing a cell density-dependent regulation system called quorum sensing (QS). Its genome contains three genes, here designated bgaI1 to bgaI3, encoding distinct autoinducer-1 (AI-1) synthases, which are capable of synthesizing QS
Ye Lin et al.
Nature communications, 6, 6824-6824 (2015-04-11)
Mixed ionic-electronic conductors are widely used in devices for energy conversion and storage. Grain boundaries in these materials have nanoscale spatial dimensions, which can generate substantial resistance to ionic transport due to dopant segregation. Here, we report the concept of
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