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Showing 1-30 of 3589 results for "493546" within Papers
Dongxia Hou et al.
PloS one, 10(11), e0142442-e0142442 (2015-11-12)
Trophoblasts (TR) are specialized cells of the placenta and play an important role in embryo implantation. The in vitro culture of trophoblasts provided an important tool to investigate the mechanisms of implantation. In the present study, porcine trophoblast cells were
Joo Youn Oh et al.
Investigative ophthalmology & visual science, 55(11), 7628-7635 (2014-11-06)
Mesenchymal stem/stromal cells (MSCs) facilitate the regeneration of injured tissue. Our group has previously shown that human MSCs (hMSCs) or hMSC-derived factors suppress excessive inflammatory response in the cornea following chemical injury in vivo. We here investigated direct effects of
T Hosoya et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(8), 1112-1121 (2014-05-17)
Transient receptor potential channel melastatin 8 (TRPM8) is activated by cold temperatures and cooling agents (menthol and icilin). Recent studies showed TRPM8 is expressed in visceral organs and peripheral sensory pathways. However, the role of TRPM8 in visceral hyperalgesia is
Russell J H Ryan et al.
Cancer discovery, 5(10), 1058-1071 (2015-08-01)
B-cell lymphomas frequently contain genomic rearrangements that lead to oncogene activation by heterologous distal regulatory elements. We used a novel approach called "pinpointing enhancer-associated rearrangements by chromatin immunoprecipitation," or PEAR-ChIP, to simultaneously map enhancer activity and proximal rearrangements in lymphoma
Qiao Zhao et al.
Phytochemistry, 112, 170-178 (2014-08-12)
Pinoresinol reductase (PrR) catalyzes the conversion of the lignan (-)-pinoresinol to (-)-lariciresinol in Arabidopsis thaliana, where it is encoded by two genes, PrR1 and PrR2, that appear to act redundantly. PrR1 is highly expressed in lignified inflorescence stem tissue, whereas
Alexander P Scott et al.
Steroids, 88, 26-35 (2014-06-15)
Interpretation of plasma cortisol levels in wild-caught fish is confounded by the stress of capture. Measurement of cortisol metabolites in fish bile could provide a method for assessing the stress level of wild fish because the time-lag for metabolism, conjugation
S Bascil et al.
Bratislavske lekarske listy, 115(9), 588-592 (2014-10-17)
Acromegaly is a complex syndrome which influences the connective tissue and bone metabolism. Although the effects of excess growth hormone on bone tissue are well known, its effect on periodontal tissue is an enigma. A total of 23 acromegalic patients
Ignacio Gonzalez Segura et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 44(3), 178-184 (2014-07-30)
Prevention and early diagnosis have the greatest potential for public health and are the most effective method in the long-term to control oral cancer. The aim was to apply PAP staining together with AgNOR staining and morphometric analysis in oral
Julie M Quach et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(5), 886-897 (2014-11-25)
Skeletal-related events resulting from accelerated bone loss are common complications in patients treated for a range of cancers. However, the mechanisms and rate of bone loss after myelosuppression are unclear. We, therefore, investigated this in mice and humans. We treated
Guoqing Wang et al.
Neuropeptides, 54, 79-83 (2015-09-10)
Exogenous administration of prolactin-releasing peptide (PrRP) exerts anorexigenic effects in rats while causing orexigenic effects in chicks. While the central mechanism mediating PrRP's effect on food intake in rodents is somewhat understood, in chicks information is lacking. Therefore, this study
Tawut Rudtanatip et al.
Fish & shellfish immunology, 47(1), 231-238 (2015-09-13)
Previous studies demonstrated that sulfated galactans (SG) from Gracilaria fisheri (G. fisheri) exhibit immunostimulant activity in shrimp. The present study was conducted to test the hypothesis that SG stimulates signaling molecules of the immune response of shrimp by binding to
Mirko Basen et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(49), 17618-17623 (2014-11-05)
Bioethanol production is achieved by only two metabolic pathways and only at moderate temperatures. Herein a fundamentally different synthetic pathway for bioalcohol production at 70 °C was constructed by insertion of the gene for bacterial alcohol dehydrogenase (AdhA) into the
Min Jung Kim et al.
Experimental biology and medicine (Maywood, N.J.), 240(4), 477-487 (2014-09-27)
Since Korean mistletoe (Viscum album) has been used for alleviating metabolic diseases, it may also prevent the impairment of energy, glucose, lipid, and bone metabolisms in an estrogen-deficient animal model. We determined that long-term consumption of Korean mistletoe water extract
Nidhi Nath et al.
Journal of immunological methods, 426, 95-103 (2015-09-01)
Antibodies labeled with small molecules such as fluorophore, biotin or drugs play an important role in various areas of biological research, drug discovery and diagnostics. However, the majority of current methods for labeling antibodies is solution-based and has several limitations
Zhe-Yi Hu et al.
Clinical pharmacokinetics, 53(9), 825-836 (2014-08-12)
Human carboxylesterase-1 (CES1) is an enzyme that is primarily expressed in the liver, where it plays an important role in the metabolism of many commonly used medications. Ethanol (alcohol)-mediated inhibition of CES1 and loss-of-function polymorphisms in the CES1 gene can
Shan Yu et al.
Cell research, 25(12), 1352-1367 (2015-11-28)
Biofilms are surface-associated communities of microorganism embedded in extracellular matrix. Exopolysaccharide is a critical component in the extracellular matrix that maintains biofilm architecture and protects resident biofilm bacteria from antimicrobials and host immune attack. However, self-produced factors that target the
Mohammad Mahdi Tavakoli et al.
ACS nano, 9(10), 10287-10295 (2015-08-19)
Flexible thin film solar cells have attracted a great deal of attention as mobile power sources and key components for building-integrated photovoltaics, due to their light weight and flexible features in addition to compatibility with low-cost roll-to-roll fabrication processes. Among
Xiaojun Qiu et al.
Pathology, research and practice, 211(10), 717-725 (2015-08-26)
Overexpression of chaperonin containing t-complex polypeptide 1 (TCP1), or CCT, has been reported in various classes of malignancies. However, little is known about the expression of t-complex protein subunits TCP1theta (CCT8) in gliomas. In this study, the expression of CCT8
Qingmei Liu et al.
International immunopharmacology, 25(2), 465-473 (2015-03-10)
The prevalence of food allergy has increased in Asian countries. Marine algae have been proposed as the potential resource for anti-allergic therapeutics. The present study was aimed at isolating R-phycocyanin (RPC) from Porphyra haitanensis and determining the anti-allergy potential of
Matthew Hennig et al.
The Journal of surgical research, 154(2), 187-195 (2009-03-27)
Chronic ethanol intake is a significant risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC). The effects of ethanol on extracellular signal-regulated kinase (ERK) activation, transforming growth factor alpha (TGF-alpha), and HCC growth were examined in this study.
Erin M Rock et al.
Psychopharmacology, 231(16), 3207-3215 (2014-03-07)
The effectiveness of cannabidiolic acid (CBDA) was compared with other potential treatments for anticipatory nausea (AN), using a rat model of contextually elicited conditioned gaping reactions. The potential of ondansetron (OND), Δ(9)-tetrahydrocannabinol (THC), chlordiazepoxide (CDP), CBDA, and co-administration of CBDA
Nehal Ibrahim et al.
International journal of pharmaceutics, 495(2), 671-679 (2015-09-19)
More than 40 years after its discovery, artemisinin has become the most promising antimalarial agent. However, no intravenous formulation is available due to its poor aqueous solubility. Here, we report the preparation, characterization, and in vitro and in vivo biological
Anshul Sharma et al.
Macromolecular bioscience, 15(2), 200-214 (2014-10-11)
Here we report on the modular synthesis and characterization of biodegradable, controlled porous, liquid crystal elastomers (LCE) and their use as three-dimensional cell culture scaffolds. The elastomers were prepared by cross-linking of star block-co-polymers with pendant cholesterol units resulting in
Auemphon Mordmuang et al.
Nutrients, 7(10), 8503-8517 (2015-10-27)
Bovine mastitis is one of the most important infectious diseases in dairy herds, and staphylococci are the most important etiologic agents of this disease. Antibiotics and chemical agents used in livestock for prevention and cure of the disease can accumulate
Chih-Hung Chiang et al.
Cell transplantation, 24(3), 541-559 (2015-02-11)
Acute hepatic failure (AHF) is a severe liver injury leading to sustained damage and complications. Induced pluripotent stem cells (iPSCs) may be an alternative option for the treatment of AHF. In this study, we reprogrammed human dental pulp-derived fibroblasts into
Constantin Scharlach et al.
Nanomedicine : nanotechnology, biology, and medicine, 11(5), 1085-1095 (2015-02-11)
To further optimize citrate-stabilized VSOPs (very small iron oxide particles, developed for MR angiography) for identification of atherosclerotic plaques, we modified their surface during synthesis using eight other acids for electrostatic stabilization. This approach preserves effective production for clinical application.
Tuo Wang et al.
Nanoscale, 7(1), 77-81 (2014-08-13)
This paper describes the synthesis of Au nanoparticle sensitized ZnO nanopencil arrays on F-doped SnO2 substrates by an aqueous chemical growth and subsequent photoreduction method. The Au-ZnO nanopencil arrays yield a photocurrent of ∼ 1.5 mA cm(-2) at 1 V
Te-Jin Chow et al.
Bioresource technology, 184, 33-41 (2014-12-03)
In this work, a recombinant cyanobacterium strain with increased photosynthesis rate, cell growth and carbohydrate production efficiency was genetically engineered by co-expressing ictB, ecaA, and acsAB (encoded for bacterial cellulose) in Synechococcus elongatus PCC7942. The resulting cyanobacterial biomass could be
Fei Guo et al.
Oncotarget, 6(33), 34606-34616 (2015-09-30)
Suppressor of cytokine signaling 3 (SOCS3) is regarded as a vital repressor in the liver carcinogenesis mainly by inhibiting signal transducer and activator of transcription 3 (STAT3) activity. Farnesoid X Receptor (FXR), highly expressed in liver, has an important role
Huanqing Li et al.
OncoTargets and therapy, 8, 3245-3253 (2015-11-26)
To investigate the role of miR-21 in cyclooxygenase-2 inhibitor NS398-induced apoptosis and invasion in gastric cancer (GC) cells. AGS cells were treated with NS398 and transfected with miR-21. Quantitative real-time polymerase chain reaction was used to measure miR-21 mRNA expression.
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