51-78-5

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Showing 31-60 of 63 results for "51-78-5" within Papers

Effect of Daptomycin Dose on the Outcome of Vancomycin-Resistant, Daptomycin-Susceptible Enterococcus faecium Bacteremia.

Yu-Chung Chuang et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 64(8), 1026-1034 (2017-03-23)

Treatment options for vancomycin-resistant enterococci (VRE) bloodstream infection (BSI) are limited. Daptomycin, although not currently approved for this indication, is frequently used for the treatment of VRE-BSI. Its optimal dose still needs to be determined. We conducted a prospective, observational

Phenotypic and genotypic detection of β-lactamases in Acinetobacter spp. isolates recovered from Lebanese patients over a 1-year period.

Micheline Hajjar Soudeiha et al.

Journal of global antimicrobial resistance, 12, 107-112 (2017-10-08)

The aim of this study was to determine the prevalence of β-lactamases in Acinetobacter spp. recovered from Lebanese patients over a 1-year period using phenotypic and molecular methods. A total of 100 non-duplicate consecutive Acinetobacter spp. isolates were collected from

Expression of progesterone and estradiol receptors in normal adrenal cortex, adrenocortical tumors, and primary pigmented nodular adrenocortical disease.

Patricia de Cremoux et al.

Endocrine-related cancer, 15(2), 465-474 (2008-05-30)

Adrenal tumors occur more frequently in women and are the leading cause of Cushing's syndrome during pregnancy. We aimed to evaluate the potential role of sex steroids in the susceptibility of women to adrenocortical tumors. We evaluated the presence of

Transmitted Drug Resistance Among Recently Diagnosed Adults and Children in São Paulo, Brazil.

Paula Morena de Souza Guimarães et al.

AIDS research and human retroviruses, 31(12), 1219-1224 (2015-04-01)

Transmitted drug resistance mutations (TDRM) have been a constant threat to treatment efficacy. We evaluated TDRM in plasma RNA of 217 antiretroviral therapy-naive patients from sites in the São Paulo metropolitan area, collected from 2012 to 2014. The partial HIV-1

The prognostic value of tumor markers in newly diagnosed patients with primary central nervous system germ cell tumors.

AeRang Kim et al.

Pediatric blood & cancer, 51(6), 768-773 (2008-09-20)

To determine the impact of diagnostic serum and/or cerebrospinal fluid (CSF) alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (b-HCG) elevations on survival in newly diagnosed patients with central nervous system germ cell tumors (CNS GCT) treated with chemotherapy with the intent

Comparison of different BMI cut-offs to screen for child and adolescent obesity in urban China.

Kun Qian et al.

Public health nutrition, 23(14), 2485-2493 (2020-06-11)

To determine which set of BMI cut-offs is the most appropriate to define child and adolescent obesity in urban China. A cross-sectional study was carried out between 1 November and 31 December in 2017. Community Healthcare Center in Minhang District

Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt].

Béatrice Hechler et al.

The Journal of pharmacology and experimental therapeutics, 314(1), 232-243 (2005-03-29)

Our aim was to determine whether the newly described P2X1 antagonist NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt] could selectively antagonize the platelet P2X1 receptor and how it affected platelet function. NF449 inhibited alpha,beta-methyleneadenosine 5'-triphosphate-induced shape change (IC50 = 83 +/- 13

Gene amplification of ESR1 in breast cancers--fact or fiction? A fluorescence in situ hybridization and multiplex ligation-dependent probe amplification study.

Akishi Ooi et al.

The Journal of pathology, 227(1), 8-16 (2011-12-16)

Oestrogen receptor-alpha (ERα), encoded by the ESR1 gene located on 6q25, is a nuclear transcription factor. Since it was reported in 2007 that more than 20% of breast cancers show ESR1 gene amplification, there has been considerable controversy about its

Image Quality and Diagnostic Performance of a Digital PET Prototype in Patients with Oncologic Diseases: Initial Experience and Comparison with Analog PET.

Nghi C Nguyen et al.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(9), 1378-1385 (2015-07-15)

We report our initial clinical experience for image quality and diagnostic performance of a digital PET prototype scanner with time-of-flight (DigitalTF), compared with an analog PET scanner with time-of-flight (GeminiTF PET/CT). Twenty-one oncologic patients, mean age 58 y, first underwent

High prevalence of polymorphism and low activity of thiopurine methyltransferase in patients with inflammatory bowel disease.

Tiziana Larussa et al.

European journal of internal medicine, 23(3), 273-277 (2012-03-06)

Gene polymorphism of thiopurine methyltransferase (TPMT) correlates with decreased enzyme activity which determines a significant risk of adverse effect reactions (ADR) in patients treated with thiopurines. The aim of this study was to investigate TPMT genotype and phenotype status in

Outcome of Imatinib Treatment in Yemeni Patients With Chronic Myeloid Leukemia and the Influence of Nonadherence to Treatment and Duration of Previous Hydroxyurea Therapy.

Jameel Al-Ghazaly et al.

Clinical lymphoma, myeloma & leukemia, 20(3), e144-e153 (2020-01-28)

In a developing country like Yemen, data are limited regarding the outcome of imatinib treatment of chronic myeloid leukemia and the effect of nonadherence to imatinib treatment and previous duration of hydroxyurea treatment. A longitudinal cohort study, which included 164

BDNF Rescues RGCs But Not Intrinsically Photosensitive RGCs in Ocular Hypertensive Albino Rat Retinas.

Francisco J Valiente-Soriano et al.

Investigative ophthalmology & visual science, 56(3), 1924-1936 (2015-02-28)

To study the responses of the general population of retinal ganglion cells (Brn3a(+)RGCs) versus the intrinsically photosensitive RGCs (melanopsin-expressing RGCs [m(+)RGCs]) to ocular hypertension (OHT), the effects of brain-derived neurotrophic factor (BDNF) on the survival of axonally intact and axonally

Immunogenicity of avian influenza A/Anhui/01/2005(H5N1) vaccine with MF59 adjuvant: a randomized clinical trial.

Robert B Belshe et al.

JAMA, 312(14), 1420-1428 (2014-10-08)

The need to respond quickly to potential influenza pandemics is important. Immunologic priming (initial presentation of an antigen to allow antibody responses on revaccination) with vaccine directed toward an older avian influenza H5 strain might lead to secondary antibody responses

Characterization of the human bone sialoprotein (BSP) gene and its promoter sequence.

R H Kim et al.

Matrix biology : journal of the International Society for Matrix Biology, 14(1), 31-40 (1994-01-01)

Bone sialoprotein (BSP) is a major structural protein of the bone matrix that is specifically expressed by fully-differentiated osteoblasts. To characterize the gene and to study the tissue-and differentiation stage-specific regulation of BSP gene transcription we have isolated and partially

XRCC1 gene polymorphism for prediction of response and prognosis in the multimodality therapy of patients with locally advanced rectal cancer.

Peter P Grimminger et al.

The Journal of surgical research, 164(1), e61-e66 (2010-09-25)

Neoadjuvant treatment strategies have been developed to improve survival of patients with locally advanced rectal cancer. Since mainly patients with major histopathologic response benefit from this therapy, predictive markers are needed. The gene polymorphism of the X-ray-repair-cross complementing (XRCC1-) gene

SALL4 represents fetal gut differentiation of gastric cancer, and is diagnostically useful in distinguishing hepatoid gastric carcinoma from hepatocellular carcinoma.

Tetsuo Ushiku et al.

The American journal of surgical pathology, 34(4), 533-540 (2010-02-26)

The novel stem cell marker SALL4 has been identified as a diagnostic marker of germ cell tumors, especially yolk sac tumors, in gonadal organs. To clarify the significance of SALL4 as an oncofetal protein, we investigated SALL4 expression by immunohistochemistry

Aldosterone increases Na+ -K+ -ATPase activity in skeletal muscle of patients with Conn's syndrome.

Bunyong Phakdeekitcharoen et al.

Clinical endocrinology, 74(2), 152-159 (2010-11-04)

In Conn's syndrome, hypokalaemia normally results from renal potassium loss because of the effect of excess aldosterone on Na(+) -K(+) -ATPase in principal cells. Little is known about the effect of aldosterone on cellular potassium redistribution in skeletal muscle. Our

Outcomes of lung disease-associated pulmonary hypertension and impact of elevated pulmonary vascular resistance.

Jordan D Awerbach et al.

Respiratory medicine, 150, 126-130 (2019-04-10)

The clinical characteristics, hemodynamic changes and outcomes of lung disease-associated pulmonary hypertension (LD-PH) are poorly defined. A prospective cohort of PH patients undergoing initial hemodynamic assessment was collected, from which 51 patients with LD-PH were identified. Baseline characteristics and long-term

Flame retardant emission from e-waste recycling operation in northern Vietnam: environmental occurrence of emerging organophosphorus esters used as alternatives for PBDEs.

Hidenori Matsukami et al.

The Science of the total environment, 514, 492-499 (2015-02-24)

Three oligomeric organophosphorus flame retardants (o-PFRs), eight monomeric PFRs (m-PFRs), tetrabromobisphenol A (TBBPA), and polybrominated diphenyl ethers (PBDEs) were identified and quantified in surface soils and river sediments around the e-waste recycling area in Bui Dau, northern Vietnam. Around the

Automatic registration of misaligned CT attenuation correction maps in Rb-82 PET/CT improves detection of angiographically significant coronary artery disease.

Piotr J Slomka et al.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 22(6), 1285-1295 (2015-02-24)

We aimed to evaluate the utility of fully automated software registration intended to improve CT attenuation correction (CTAC) map misalignments during cardiac (82)Rb PET/CT myocardial perfusion imaging (MPI). 171 consecutive patients (108 males, mean age 69 years), undergoing both rest-stress

Daptomycin use in neutropenic patients with documented gram-positive infections.

Kenneth V I Rolston et al.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(1), 7-14 (2013-08-27)

The goal of this study was to describe the outcomes associated with daptomycin treatment of documented gram-positive infections in patients with neutropenia. All patients with neutropenia (≤500 cells/m(3)) and at least one documented gram-positive culture from 2006-2009 were identified from

Effect of proinflammatory cytokines on gene expression of the diabetes-associated autoantigen IA-2 in INS-1 cells.

Holger Steinbrenner et al.

Endocrinology, 143(10), 3839-3845 (2002-09-20)

Cytokines released from activated antigen-presenting cells and T-lymphocytes are crucially involved in the pathogenesis of type 1 diabetes. Previous studies have shown that proinflammatory cytokines play an important role in the induction of autoimmunity and beta-cell damage. Inhibition of insulin

High levels of serum soluble CD27 correlated with renal dysfunction.

T Nakatsuji

Clinical and experimental medicine, 2(4), 192-196 (2003-03-08)

CD27 is expressed on lymphocytes, but also on renal tubules. On the damaged renal tubules, CD27 is cleaved into soluble CD27 (sCD27) and cytoplasmic tail CD27. Renal tubule apoptosis is induced by the CD27 ligand, Siva, binding to the truncated

Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer.

Ying Li et al.

PloS one, 8(1), e52093-e52093 (2013-01-24)

The EML4-ALK fusion gene has been recently identified in a small subset of non-small cell lung cancer (NSCLC) patients who respond positively to ALK inhibitors. The characteristics of the EML4-ALK fusion gene in Chinese patients with NSCLC are poorly understood.

Iron homeostasis and H63D mutations in alcoholics with and without liver disease.

Mariana Verdelho Machado et al.

World journal of gastroenterology, 15(1), 106-111 (2008-12-31)

To evaluate the prevalence of HFE gene mutation and indices of disturbed iron homeostasis in alcoholics with and without liver disease. One hundred and fifty-three heavy drinkers (defined as alcohol consumption > 80 g/d for at least 5 years) were

Defining utility and predicting outcome of cadaveric lower extremity bypass grafts in patients with critical limb ischemia.

Catherine K Chang et al.

Journal of vascular surgery, 60(6), 1554-1564 (2014-07-22)

Despite poor long-term patency, acceptable limb salvage has been reported with cryopreserved saphenous vein bypass (CVB) for various indications. However, utility of CVB in patients with critical limb ischemia (CLI) remains undefined. The purpose of this analysis was to determine

Human IgG antibody responses to severe acute respiratory syndrome coronavirus 2 viral antigens receptor-binding domain, spike, and nucleocapsid, in vaccinated adults from Merida, Mexico.

Henry Puerta-Guardo et al.

Frontiers in medicine, 9, 916241-916241 (2022-08-09)

Several vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been approved for controlling the coronavirus disease 2019 (COVID-19) pandemic worldwide. Antibody response is essential to understand the immune response to different viral targets after vaccination with different vaccine

Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan.

Nabil Karah et al.

Annals of clinical microbiology and antimicrobials, 19(1), 2-2 (2020-01-17)

Acinetobacter baumannii is a Gram-negative opportunistic pathogen with a notorious reputation of being resistant to antimicrobial agents. The capability of A. baumannii to persist and disseminate between healthcare settings has raised a major concern worldwide. Our study investigated the antibiotic

Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.

Pedro Castelo-Branco et al.

The Lancet. Oncology, 14(6), 534-542 (2013-04-20)

Identification of robust biomarkers of malignancy and methods to establish disease progression is a major goal in paediatric neuro-oncology. We investigated whether methylation of the TERT promoter can be a biomarker for malignancy and patient outcome in paediatric brain tumours.

Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.

L Tang et al.

Gene, 216(2), 255-265 (1998-09-05)

Five clustered polyketide synthase (PKS) genes, rifA-rifE, involved in rifamycin (Rf) biosynthesis in Amycolatopsis mediterranei S699 have been cloned and sequenced (August, P.R. et al., 1998. Chem. Biol. 5, 69-79). The five multifunctional polypeptides constitute a type I modular PKS

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