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Showing 1-30 of 204 results for "62-13-5" within Papers
L G Ulman et al.
Regulatory peptides, 51(1), 17-23 (1994-04-14)
Previous studies have shown that injection of galanin (GAL: 6.2 nmol/kg) causes prolonged inhibition of cardiac vagal action in anaesthetised cats. Stimulation of the cardiac sympathetic nerve (16 Hz for 5 min) also produces inhibition of cardiac vagal action, an
K Grottel et al.
Medycyna pracy, 34(5-6), 369-374 (1983-01-01)
The rats (control group--6 animals, experimental group I--13, experimental group II--8) of inbred Wistar/W Bog strain, were orally administered 84,6% technical concentrate IPO-62 (bromphenvinphose) dissolved in olive oil and next the spines on apical cortex dendrites were evaluated. Statistically significant
Michael Medinger et al.
Pathology oncology research : POR, 16(3), 295-301 (2010-02-24)
c-kit functions as a tyrosine kinase receptor and represents a target for small molecule kinase inhibitors. The expression pattern for c-kit was studied in different human tumor types to their correlation with prognosis. Paraffin-embedded tumor tissues from 282 patients were
Todd M Everson et al.
Genome medicine, 7, 89-89 (2015-08-22)
The prevalence of allergic diseases are increasing worldwide, emphasizing the need to elucidate their pathogeneses. The aims of this study were to use a two-stage design to identify DNA methylation levels at cytosine-phosphate-guanine (CpG) sites across the genome associated with
Sven Dänicke et al.
Isotopes in environmental and health studies, 48(4), 558-572 (2012-05-23)
Ergot alkaloids (sum=total alkaloids, TA) originate from the phyto-pathogenic fungus Claviceps purpurea and might exert feed intake depressing and hepatotoxic effects on animals. The aim of the study was to evaluate TA effects on performance and liver function of piglets
H Messier et al.
Journal of immunology (Baltimore, Md. : 1950), 149(6), 1980-1986 (1992-09-15)
The murine V beta 2 promoter was analyzed for an element regulating phorbol ester inducibility of the TCR beta chain gene. In transient expression analysis of 5' nested deleted fragments of the V beta 2 promoter, the TPA-inducible element mapped
Sara Marinelli et al.
BMC cancer, 14, 403-403 (2014-06-07)
Development of escape pathways from antiangiogenic treatments was reported to be associated with enhanced tumor aggressiveness and rebound effect was suggested after treatment stop. Aim of the study was to evaluate tumor response simulating different conditions of administration of antiangiogenic
Atsushi Shamoto et al.
Journal of cardiovascular medicine (Hagerstown, Md.), 13(11), 747-754 (2012-08-24)
Efficacy and safety of long-term administration of bepridil as a rhythm and rate controller were comprehensively evaluated in patients with multidrug-resistant paroxysmal atrial fibrillation (PAF). A retrospective survey from 1992 to 2006 was conducted on 62 multidrug-resistant PAF patients treated
Juan C Marini et al.
American journal of physiology. Endocrinology and metabolism, 303(11), E1348-E1353 (2012-10-18)
Citrulline is an amino acid synthesized in the gut and utilized for the synthesis of the conditionally essential amino acid arginine. Recently, the origin of the ornithine utilized for citrulline synthesis has become a matter of discussion. Multiple physiological factors
T Nagano et al.
Journal of dental research, 88(9), 823-828 (2009-09-22)
Mmp-20 and Klk4 are the two key enamel proteases. Can both enzymes process amelogenin to generate the major cleavage products that accumulate during the secretory stage of amelogenesis? We isolated Mmp-20 and Klk4 from developing pig teeth and used them
Julian Robert James Adams et al.
Matrix biology : journal of the International Society for Matrix Biology, 25(1), 40-46 (2005-10-06)
The expression of hyaluronan synthases (1, 2 and 3) and hyaluronidases (1, 2, 3, 4 and PH20) was examined in the MG63 osteoblast cell line induced to mineralize in vitro and compared to the rate of glycosaminoglycan production. Real-time PCR
Piotr Wójcik et al.
Polish journal of pathology : official journal of the Polish Society of Pathologists, 59(2), 93-96 (2008-08-02)
Oncogenic KRAS mutations are associated with resistance to anti-EGFR therapy in colorectal carcinoma. Since anti-EGFR monoclonal antibodies are employed in clinical practice in advanced colorectal cancer, KRAS mutations have become an important predictor of therapy outcome. Mutational analysis of KRAS
T C Liu et al.
American journal of hematology, 63(4), 170-175 (2000-03-08)
Recently, a putative tumor suppressor gene, PTEN/MMAC1, has been identified at chromosome 10q23.3, which encodes a 403 amino acid dual-specificity phosphatase containing a region of homology to tensin and auxillin. Somatic mutations of the PTEN/MMAC1 gene have been identified in
Szlavik et al.
Organic letters, 2(15), 2347-2349 (2000-08-10)
A convenient and effective method for the preparation of perfluoroalkylated ethenes is described. First, the free radical addition of perfluoroalkyl iodides to trimethylvinylsilane in the presence of AIBN gave iodoethylsilane intermediates (F(CF(2))(n)()CH(2)CHISiMe(3), n = 4 (1), 6 (2), 8 (3)
K Ray et al.
The Journal of biological chemistry, 266(10), 6221-6229 (1991-04-05)
The complete rat vitamin D binding protein (DBP) gene has been cloned and characterized. Genomic mapping suggests that there is only one copy of this gene in the haploid genome. The gene spans 35 kilobase pairs and contains 13 exons.
Si-Yuan Wen et al.
World journal of gastroenterology, 9(6), 1342-1346 (2003-06-12)
Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme responsible for the metabolism of a large number of clinically important drugs. Individuals with mutant enzymes may risk serious side effects under routine therapy with certain drugs metabolized by CYP2C9. In order
Paolo Indolfi et al.
Cancer, 119(8), 1586-1592 (2013-01-12)
The optimal management of bilateral Wilms tumor (BWT) is challenging, and their survival is lower than for unilateral tumors. This report discusses a large series of BWTs treated in Italy in the last 2 decades. This analysis concerns patients with
Henrik Gutte et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(11), 1786-1792 (2015-09-05)
With the introduction of combined PET/MR spectroscopic (MRS) imaging, it is now possible to directly and indirectly image the Warburg effect with hyperpolarized (13)C-pyruvate and (18)F-FDG PET imaging, respectively, via a technique we have named hyperPET. The main purpose of
Michelle A Fanale et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(28), 3137-3143 (2014-08-20)
Front-line treatment of peripheral T-cell lymphomas (PTCL) involves regimens such as cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) and results in a 5-year overall survival (OS) rate of less than 50%. This phase I open-label study evaluated the safety and activity of
Yisong Wang et al.
Scientific reports, 4, 7336-7336 (2014-12-09)
Genetic alterations and etiology of thymic epithelial tumors (TETs) are largely unknown, hampering the development of effective targeted therapies for patients with TETs. Here TETs of advanced-stage patients enrolled in a clinical trial of molecularly-guided targeted therapies were employed for
Jemima Tiwaa Marfo et al.
PloS one, 10(11), e0142172-e0142172 (2015-11-05)
Neonicotinoid insecticides are nicotinic acetylcholine receptor agonists used worldwide. Their environmental health effects including neurotoxicity are of concern. We previously determined a metabolite of acetamiprid, N-desmethyl-acetamiprid in the urine of a patient, who exhibited some typical symptoms including neurological findings.
X Zhong et al.
Human mutation, 15(3), 296-297 (2000-02-19)
The E2F family of transcription factors regulates the expression of genes required for DNA synthesis and cell cycle control. The AGC triplet repeat in the coding region of the E2F-4 gene, a member of the family, has been reported to
Y Anouar et al.
The Journal of biological chemistry, 269(9), 6823-6831 (1994-03-04)
The gene encoding the neuropeptide galanin is upregulated by second messenger signal transduction pathways in bovine chromaffin cells. To identify its transcriptional regulatory elements, 5'-flanking sequences of the galanin gene were transiently transfected into primary cultures of bovine chromaffin cells
H Kamata et al.
Clinical and experimental medicine, 7(2), 39-46 (2007-07-05)
To clarify whether p53 mutation could be involved in the pathogenesis of various subtypes of lymphoma, we investigated 62 Japanese cases of non-Hodgkin's lymphomas (NHLs) for p53 gene mutations and their relationship with the expression of p53 protein. Mutations in
Thierry Vilboux et al.
Human mutation, 30(12), 1611-1619 (2009-10-29)
Alkaptonuria (AKU) is a rare autosomal recessive metabolic disorder, characterized by accumulation of homogentisic acid, leading to darkened urine, pigmentation of connective tissue (ochronosis), joint and spine arthritis, and destruction of cardiac valves. AKU is due to mutations in the
L Zahradova et al.
Neoplasma, 59(4), 440-449 (2012-04-12)
In a phase II clinical study, pretreated multiple myeloma patients with relapsing or stable disease received autologous anticancer vaccine containing dendritic cells loaded with Id-protein. Patients received a total of 6 vaccine doses intradermally in monthly intervals. No clinical responses were observed.
Ai-guo Liu et al.
Zhonghua er ke za zhi = Chinese journal of pediatrics, 47(10), 785-788 (2009-12-22)
To investigate the expression of CD147 and matrix metalloproteinase-9 (MMP-9) in children with non-Hodgkin's lymphoma (NHL) and its correlation with clinical stage, tumor size, bone marrow invasion, immunological typing, serum lactate dehydrogenase (LDH) concentration, and prognosis. Specimens excised from NHL
Leon Alexander Danyel et al.
Ultrasound in medicine & biology, 46(8), 1889-1895 (2020-05-23)
Transcranial color-coded duplex sonography (TCCS) and computed tomography angiography (CTA) are widely used to identify intracranial stenoses (ISs). We assessed concordance of IS grading between TCCS and CTA and proposed new TCCS criteria for severe IS ≥70%. One hundred two
Tadashi Terada
International journal of clinical and experimental pathology, 6(3), 485-491 (2013-02-16)
Small cell neuroendocrine carcinoma of the esophagus (SCNECE) is a very rare, but a highly aggressive tumor. Six cases of SCNECE (0.25%) were found in the 2,438 archival pathologic specimens of esophagus in the last 20 years in our pathology
John Lekakis et al.
International journal of cardiology, 127(1), 46-50 (2007-06-15)
There is considerable research interest about the platelet GPIIb/IIIa receptor polymorphisms in CAD. We investigated differences in the frequency of the polymorphism in the GPIIb subunit of the receptor HPA-3 (a and b allele) between patients with more extensive coronary
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