CN
Search Within
62-13-5
Applied Filters:
Keyword:'62-13-5'
Showing 31-60 of 204 results for "62-13-5" within Papers
T Watanabe et al.
Biochimica et biophysica acta, 1304(2), 161-169 (1996-11-22)
In a previous study, we characterized prostanoid and thrombin receptors expressed on a megakaryoblastic cell line, MEG-01s (Blood 78, 2328-2336, 1991). In this study, we examines the mechanism of cross-talk between intracellular Ca2+ ([Ca2+]i) and cAMP signalings through prostanoid and
Zhi-Gang Sun et al.
Fa yi xue za zhi, 22(4), 271-274 (2006-11-04)
To establish a method which processes RHCE genotyping with PCR. Using PCR-SSP to detect RHCE genotype in 200 cases of Han population in north of China and Li population in south of China and detecting 5 samples of parentage testing
Victor Palomino-Tapia et al.
Virology, 522, 138-146 (2018-07-22)
Viral Arthritis (VA), a disease caused by Avian Reovirus (ARV), has emerged as a significant cause of economic losses in broiler chicken flocks in Western Canada. These outbreaks were characterized by 4-13% morbidity, followed by a spike in mortality/culling that
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices.
Gabriella Nyitrai et al.
Brain research, 1309, 172-178 (2009-11-17)
A wide range of data support a role for ambient glutamate (Glu) in epilepsy, although temporal patterns associated with the cellular uptake of Glu have not been addressed in detail. We report on the effects of Glu uptake inhibitors on
Toshihiro Akihisa et al.
Chemistry & biodiversity, 10(3), 313-327 (2013-03-16)
The MeOH extract of moxa, the processed leaves of Artemisia princeps PAMP. (Asteraceae), exhibited potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and melanogenesis-inhibitory activity in α-melanocyte-stimulating hormone (α-MSH)-stimulated B16 melanoma cells. Eight caffeoylquinic acids, 1 and 6-12, five flavonoids, 13-17, two benzoic
Shuhua Tan et al.
American journal of respiratory cell and molecular biology, 36(6), 737-745 (2007-02-17)
Mucin glycan is the primary determinant of mucin functions. These functions are expanded by three branch structures, including core 2, core 4, and blood group I, which are synthesized by core 2 beta1,6 N-acetylglucosaminyltransferase-M (C2GnT-M). Alteration of C2GnT-M gene expression
Nazim Isma et al.
Thrombosis research, 125(6), e335-e338 (2010-04-22)
Deep venous thrombosis (DVT) is much less common in the upper than in the lower extremity. Furthermore, there is limited information on risk factors for and the prognosis of upper extremity (UE)DVT in the general population. To estimate incidence, risk
D M Racila et al.
Lupus, 12(2), 124-132 (2003-03-13)
We report an association between a non-familial form of photosensitive Lupus-specific skin disease, subacute cutaneous lupus erythematosus (SCLE), and a new single nucleotide polymorphism (SNP) in the C1QA gene. We also describe an association between this SNP and lower levels
A Thabaut et al.
Pathologie-biologie, 42(5), 369-374 (1994-05-01)
The antibacterial activities of pefloxacin (PEF), ofloxacin (OFL), ciprofloxacin (CIP) were measured by agar diffusion (5 micrograms strength disks) against 6370 non duplicate clinical isolates collected in November 1991 in 40 hospitals from various areas in France. The MICs of
M I Lomax et al.
Mammalian genome : official journal of the International Mammalian Genome Society, 6(2), 118-122 (1995-02-01)
We have isolated the bovine COX8H gene for the heart/muscle isoform of cytochrome c oxidase (COX) subunit VIII from a library of bovine genomic DNA cloned into lambda EMBL3. Primer extension assays on bovine heart mRNA mapped the 5' ends
Mohammed K Khuthaila et al.
American journal of ophthalmology, 155(4), 757-763 (2013-01-16)
To report the frequency of postoperative vitreous hemorrhage (VH) in eyes that underwent primary 23-gauge pars plana vitrectomy (PPV) for nonclearing VH resulting from proliferative diabetic retinopathy, as well as associated risk factors. Retrospective, consecutive, interventional case series. Institutional (Retina
M Meier et al.
Leukemia, 19(11), 1887-1895 (2005-09-17)
The T-lineage phenotype in children with acute lymphoblastic leukaemia (ALL) is associated with in vitro drug resistance and a higher relapse-risk compared to a precursor B phenotype. Our study was aimed to investigate whether mutations in the ATM gene occur
Hector Corominas et al.
Medicina clinica, 126(11), 410-412 (2006-04-06)
Thiopurine S-methyltransferase (TPMT) metabolizes thiopurine drugs regulating their cytotoxicity and clinical response. TPMT activity is inherited as an autosomal recessive trait and several mutations in the TPMT gene have been identified which correlate with a low activity phenotype. A variable
Hei-ying Jin et al.
Zhonghua yi xue za zhi, 91(41), 2891-2894 (2012-02-16)
To explore the roles of hairy enhancer of split 1 (Hes1) gene in colorectal cancer and analyze its clinical significance. A total of 146 cases with colorectal cancer at our hospital were collected prospectively and followed up. There were 84
Jing Chen et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(19), 3363-3367 (2014-01-16)
The study aimed to develop the assay of chrysosplenetin (CHR), a metabolic inhibitor of artemisinin by UPLC-MS/MS in rat plasma and investigate the pharmacokinetics parameters of CHR. The plasma samples were precipitated by acetonitrile to remove the proteins. Separation was
Cory Toth et al.
Pain, 153(10), 2073-2082 (2012-08-28)
Cannabinoids are emerging as potential options for neuropathic pain treatment. This study evaluated an oral cannabinoid, nabilone, in the treatment of refractory human diabetic peripheral neuropathic pain (DPN). We performed a single-center, randomized, double-blind, placebo-controlled, flexible-dose study with an enriched
B Ezquieta et al.
Clinical genetics, 62(2), 181-188 (2002-09-11)
This study addresses the contributions of gene conversion and a founder effect to the distribution of the two most frequent severe point mutations of the 21-hydroxylase (21OH) gene causing congenital adrenal hyperplasia: the 655G splicing mutation at intron 2, and
Satoshi Ogasawara et al.
Oncogene, 23(5), 1117-1124 (2004-01-27)
Cancer-associated DNA hypomethylation is as prevalent as cancer-linked hypermethylation, but the biological significance of DNA hypomethylation in carcinogenesis is less understood. The expression of Maspin (mammary serpin) in differentiated normal cells is regulated by epigenetic modifications in a cell-type-specific manner.
Evangelia Peponi et al.
The American journal of pathology, 169(6), 2171-2180 (2006-12-07)
Mantle cell lymphoma (MCL) is characterized by the t(11;14) and cyclin D1 overexpression. However, additional molecular events are most likely required for oncogenesis, possibly through cell cycle and apoptosis deregulation. We hypothesized that mammalian target of rapamycin (mTOR) is activated
S Hossein Fatemi et al.
Cellular and molecular neurobiology, 22(2), 139-152 (2002-10-05)
1. Autism is a severe neurodevelopmental disorder with potential genetic and environmental etiologies. Recent genetic linkage reports and biochemical analysis of postmortem autistic cerebellum point to Reelin, an important secretory extracellular protein, as being involved in the pathology of autism.
Karin Stadlbauer et al.
American journal of physiology. Endocrinology and metabolism, 297(3), E785-E792 (2009-07-23)
Two mechanisms have been proposed for the modulation of skeletal muscle glucose metabolism by amino acids. Whereas studies on humans and cultured cells suggested acute insulin desensitization via mammalian target of rapamycin (mTOR) and its downstream target p70 S6 kinase
Aaron M Bender et al.
Cancer research, 70(9), 3557-3565 (2010-04-15)
The Sleeping Beauty (SB) transposon system has been used as an insertional mutagenesis tool to identify novel cancer genes. To identify glioma-associated genes, we evaluated tumor formation in the brain tissue from 117 transgenic mice that had undergone constitutive SB-mediated
C R Herzog et al.
Oncogene, 13(9), 1885-1891 (1996-11-07)
The genes of murine cyclin D-dependent kinase inhibitors, p15INK4b and p16INK4a, are located in a region of chromosome 4 where overlapping deletions were found in lung adenocarcinomas. The p16INK4a gene uniquely consists of alternative first exons (E1alpha and E1beta), which
R Seth et al.
Gut, 58(9), 1234-1241 (2009-05-29)
KRAS and BRAF mutations occur in colorectal cancers (CRCs) and are considered mutually exclusive methods of activating the RAS/RAF/MEK/ERK pathway. This pathway is a therapeutic target and KRAS mutation may predict tumour responsiveness. The purpose of this study was to
Robert Clough et al.
Talanta, 199, 425-430 (2019-04-07)
High quality observational data with a firm uncertainty assessment are essential for the proper validation of biogeochemical models for trace metals such as iron. Typically, concentrations of these metals are very low in oceanic waters (nM and sub nM) and
Hye-Ja Lee et al.
Human heredity, 60(2), 73-80 (2005-09-17)
We investigated sequence variations of the 29-kb insulin-like growth factor 2 (IGF2) region in human chromosome region 11p15.5 in the Korean population. This region consists of IGF2, insulin-like growth factor 2 antisense (IGF2AS), and the insulin gene, all important candidate
Wael Ahmad et al.
VASA. Zeitschrift fur Gefasskrankheiten, 49(1), 23-29 (2019-09-25)
Background: The aim of this study is to evaluate perioperative as well as long-term outcomes in patients operated with carotid endarterectomy (CEA) or stenting (CAS) due to symptomatic or asymptomatic high-grade restenosis of the internal carotid artery (ICA). Patients and
Zhanpeng Li et al.
Indian journal of biochemistry & biophysics, 49(3), 165-172 (2012-07-19)
Generally, extra-cellular-signal-regulated kinase 5 (ERK5) signaling pathway regulates many physiological activities, such as cell proliferation and cell differentiation. However, little is known about how ERKS signaling pathway composed of 15 paths participates in regulating hepatocyte proliferation during liver regeneration (LR).
Wei-Jia Fang et al.
Oncology reports, 27(5), 1606-1610 (2012-02-11)
S-1 is an oral antitumor agent that contains tegafur, which is converted to fluorouracil (5-FU) in the human body. Cytochrome P450 2A6 (CYP2A6) is the principal enzyme responsible for bioconversion of tegafur to 5-FU. A number of CYP2A6 polymorphisms have
Caio Max Rocha-Lima et al.
Cancer chemotherapy and pharmacology, 74(3), 479-486 (2014-07-18)
The G17DT is a novel human immunogen that raises antibodies to the growth factor gastrin 17 (G17). The purpose of this study was to determine the safety and efficacy of G17DT in combination with irinotecan in patients refractory to irinotecan
Page 2 of 7