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Showing 31-60 of 85 results for "62-56-6" within Papers
Florian van Bömmel et al.
Hepatology (Baltimore, Md.), 61(1), 66-76 (2014-08-19)
Hepatitis B envelope antigen (HBeAg) seroconversion represents an endpoint of treatment of chronic hepatitis B virus (HBV) infections. We have studied whether levels of serum HBV RNA during polymerase inhibitor treatment might be helpful for predicting HBeAg seroconversion. HBV RNA
S O Peters et al.
Experimental hematology, 23(5), 461-469 (1995-05-01)
Stimulatory cytokines may induce murine hematopoietic progenitor cells (HPCs) to survive, self-renew, proliferate, or differentiate. We studied the role of active cell cycling induced by the cytokines interleukin-3 (IL-3), IL-6, IL-11, and Steel factor (SF) on murine progenitor cell frequency
Yuka Fujimoto et al.
American journal of physiology. Endocrinology and metabolism, 287(3), E414-E423 (2004-05-13)
Hepatic glucose fluxes and intracellular movement of glucokinase (GK) in response to increased plasma glucose and insulin were examined in 10-wk-old, 6-h-fasted, conscious Zucker diabetic fatty (ZDF) rats and lean littermates. Under basal conditions, plasma glucose (mmol/l) and glucose turnover
Elif Sare Koytak et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 19(4), 245-249 (2009-01-03)
Several lines of evidence suggest that peroxisome proliferator-activated receptor alpha may be involved in hepatocarcinogenesis. L162V polymorphism of the peroxisome proliferator-activated receptor alpha gene enhances the transactivation activity of this transcription factor. The aim of this study was to determine
Mikel Garcia-Marcos et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 25(2), 590-599 (2010-10-27)
Metastasis accounts for the majority of cancer-related deaths. Accurate prediction of metastatic potential of tumors has been elusive, and the search for clinically useful markers continues. We previously reported that GIV/Girdin triggers tumor cell migration by virtue of a C-terminal
Xiaoxu Gao et al.
Molecules (Basel, Switzerland), 23(9) (2018-09-12)
Herba Siegesbeckiae (HS), derived from the aerial parts of three plants, Siegesbeckia orientalis (SO), S. glabrescens (SG), and S. pubescens (SP), has been used for the treatment of inflammatory diseases in China for centuries. In the present study, hydrodistillation was
Alejandra González-Duarte et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 19(4), 171-176 (2012-08-30)
The phenotypic heterogeneity of transthyretin amyloidosis (ATTR) familial polyneuropathy may be linked to the type of mutation and to the environmental factors. A gender difference in relation to the severity of the disease has been suspected. More than 100 different
Lu-Te Chuang et al.
Molecules (Basel, Switzerland), 26(3) (2021-01-28)
Cutibacterium acnes (formerly Propionibacterium acnes) is one of the major bacterial species responsible for acne vulgaris. Numerous bioactive compounds from Momordica charantia Linn. var. abbreviata Ser. have been isolated and examined for many years. In this study, we evaluated the
N L Ward et al.
Brain research. Developmental brain research, 118(1-2), 79-91 (1999-12-28)
The low-affinity nerve growth factor receptor (p75(NGFR)) apparently can mediate apoptosis in a variety of cells in vitro and in vivo. Previously, our laboratory suggested that p75(NGFR) induced apoptosis in a subpopulation of cholinergic forebrain neurons during postnatal development, i.e.
Annalisa Berzigotti et al.
Hepatology (Baltimore, Md.), 65(4), 1293-1305 (2016-12-21)
Obesity increases the risk of clinical decompensation in cirrhosis, possibly by increasing portal pressure. Whether weight reduction can be safely achieved through lifestyle (LS) changes (diet and exercise) in overweight/obese patients with cirrhosis, and if weight loss reduces portal pressure
Christos Haritoglou et al.
Retina (Philadelphia, Pa.), 26(6), 618-622 (2006-07-11)
To report on long-term results of macular hole surgery with peeling of the internal limiting membrane (ILM) in a prospective nonrandomized study. Sixty-four consecutive patients with a follow-up of at least 36 months were included. Only idiopathic macular holes were
Kristine Yaffe et al.
Biological psychiatry, 51(8), 677-682 (2002-04-17)
Several genes associated with sporadic Alzheimer's disease have been identified; however, approximately 50% of genetic factors remain unidentified. We investigated whether estrogen receptor 1 (ESR1) polymorphisms are associated with risk of developing cognitive impairment in older women. A total of
Kristina A Thomsson et al.
Glycobiology, 12(1), 1-14 (2002-02-05)
The high-molecular-mass salivary mucin MG1, one of two major mucins produced by human salivary glands, plays an important role in oral health by coating the tooth surface and by acting as a bacterial receptor. Here this mucin was purified from
Kristina A Thomsson et al.
Glycobiology, 12(1), 1-14 (2002-02-05)
The high-molecular-mass salivary mucin MG1, one of two major mucins produced by human salivary glands, plays an important role in oral health by coating the tooth surface and by acting as a bacterial receptor. Here this mucin was purified from
Djordje Atanackovic et al.
Blood, 109(3), 1103-1112 (2006-10-07)
Immunotherapies using cancer-testis (CT) antigens as targets represent a potentially useful treatment in patients with multiple myeloma (MM) who commonly show recurrent disease following chemotherapy. We analyzed the expression of 11 CT antigens in bone marrow samples from patients with
Pablo A Ortiz et al.
American journal of physiology. Renal physiology, 287(2), F274-F280 (2004-04-08)
Nitric oxide (NO) produced by endothelial NO synthase (eNOS) acts as an autacoid to inhibit NaCl absorption in the thick ascending limb of the loop of Henle (THAL). In the vasculature, shear stress activates eNOS. We hypothesized that increasing luminal
Anna Panovská et al.
European journal of haematology, 90(6), 479-485 (2013-03-20)
There are minimal data about the efficacy of subsequent therapy in patients with relapse after FCR (fludarabine, cyclophosphamide, and rituximab) chemoimmunotherapy. We retrospectively analyzed the outcomes of 119 patients who relapsed after standard-dose FCR. The patient cohort consisted of patients
Martina Buresova et al.
Physiological genomics, 26(3), 226-231 (2006-08-18)
Epidemiological studies have shown a clear link between fetal growth retardation and an increased propensity for later cardiovascular disease in adults. It has been hypothesized that such early fetal deprivation "programs" individuals toward a life-long metabolical "thrifty phenotype" that predisposes
B M Sadler et al.
Journal of clinical pharmacology, 41(4), 386-396 (2001-04-18)
The objective of this study was to determine the metabolic profile, routes of elimination, and total recovery of amprenavir and its metabolites after a single oral dose of [14C]-amprenavir. Six healthy male subjects each received a single oral 630 mg
Mohammad Reza Safarinejad et al.
The British journal of nutrition, 110(1), 164-171 (2012-12-04)
The main objective of the present study was to determine the potential of n-3 and n-6 fatty acids or coenzyme Q10 (CoQ10) to alter serum prostate-specific antigen (PSA) levels in normal healthy men. A total of 504 healthy men with
Mostafa K El Awady et al.
Cancer biomarkers : section A of Disease markers, 5(6), 233-240 (2009-12-29)
The study was planned as a pilot study to investigate two common polymorphisms in the MTHFR gene c.677C > T and c.1298A > C and their association with enhanced risk of colorectal cancer (CRC) in a sample of Egyptian individuals.
Sara S Jarvis et al.
Frontiers in physiology, 5, 86-86 (2014-03-14)
Young black women have higher prevalence of hypertension during pregnancy compared to white women, which may be attributable to differences in blood pressure (BP) regulation. We hypothesized that young normotensive black women would demonstrate augmented muscle sympathetic nerve activity (MSNA)
P J Creaven et al.
Urology, 37(2 Suppl), 13-19 (1991-01-01)
Data are available on the pharmacokinetics and metabolism of nilutamide in the rat, dog, and human (normal volunteers and patients with advanced prostatic carcinoma). Studies using 14Carbon-nilutamide, radioimmunoassay, and high-performance liquid chromatography (HPLC) are reviewed. In the rat, bioavailability by
Flemming Güttler et al.
Pediatrics, 112(6 Pt 2), 1530-1533 (2003-12-05)
The aim of the present study was to examine to what extent maternal and offspring phenylalanine hydroxylase (PAH) genotypes in conjunction with maternal IQ and dietary control during pregnancy are related to cognitive development in offspring of women with phenylketonuria
S Ali et al.
The British journal of dermatology, 174(5), 1022-1029 (2015-12-18)
Mucous membrane pemphigoid (MMP) is an uncommon mucocutaneous immunobullous disorder. Use of saliva for diagnosis by enzyme-linked immunosorbent assay (ELISA) using the noncollagenous (NC) domain 16a of bullous pemphigoid antigen II (BP180) is not well described. To establish whether whole
Bhavana Chhunchha et al.
Antioxidants (Basel, Switzerland), 10(8) (2021-08-28)
Aberrant Sumoylation-mediated protein dysfunction is involved in a variety of oxidative and aging pathologies. We previously reported that Sumoylation-deficient Prdx6K(lysine)122/142R(Arginine) linked to the TAT-transduction domain gained stability and protective efficacy. In the present study, we formulated wild-type TAT-HA-Prdx6WT and Sumoylation-deficient
M Y M Ng et al.
Journal of medical genetics, 42(3), 235-239 (2005-03-04)
The FOXC2 gene on 16q24 is mutated in lymphoedema distichiasis (LD), in which varicose veins (VV) are a common feature. We hypothesised that this gene might be implicated in the development of VV in the normal population, therefore, after performing
Hanna-Riikka Lehto et al.
The Journal of clinical endocrinology and metabolism, 97(9), 3277-3284 (2012-07-05)
We tested the hypothesis that a persistent reduction in free fatty acid (FFA) levels improves cardiac function and systemic insulin sensitivity via a reduction in the myocardial and skeletal muscle adiposities and a modulation in adipokine release. Study subjects (body
Petra van der Groep et al.
PloS one, 8(2), e56055-e56055 (2013-02-15)
Recent studies have revealed that BRCA1 and BRCA2 germline mutation-related breast cancers show frequent overexpression of hypoxia inducible factor-1α (HIF-1α), the key regulator of the hypoxia response. However, the question remained whether hypoxia is a late stage bystander or a
Feng-Cai Zhu et al.
Lancet (London, England), 381(9882), 2024-2032 (2013-06-04)
A vaccine for enterovirus 71 (EV71) is needed to address the high burden of disease associated with infection. We assessed the efficacy, safety, immunogenicity, antibody persistence, and immunological correlates of an inactivated alum-adjuvant EV71 vaccine. We did a randomised, double-blind
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