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Showing 1-30 of 57 results for "62-75-9" within Papers
Berrak Gumuskaya et al.
Cancer genetics and cytogenetics, 203(2), 222-229 (2010-12-16)
Most basal-like breast carcinomas are estrogen receptor negative, progesterone receptor negative, and cerb-B2/HER-2/neu negative--the so-called triple-negative breast carcinomas--with high epidermal growth factor receptor (EGFR) expression, which makes EGFR a target of treatment. We evaluated EGFR expression by immunohistochemistry (IHC) with
J Ott et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(2), 701-704 (1990-01-01)
Multilocus linkage analysis of 62 family pedigrees with X chromosome-linked retinitis pigmentosa (XLRP) was undertaken to determine the presence of possible multiple disease loci and to reliably estimate their map location. Multilocus homogeneity tests furnished convincing evidence for the presence
K Mochida et al.
Developmental biology, 227(2), 510-519 (2000-11-10)
Previous work in our laboratory has shown that a 62- to 64-kDa protein was a major component of the perinuclear ring of manchettes fractionated from rat spermatids. Mass spectrometry analysis of this protein indicated the presence of a glycine-rich domain
G Wess et al.
Journal of veterinary internal medicine, 24(3), 527-532 (2010-04-24)
Hypertrophic cardiomyopathy (HCM) is an inherited autosomal dominant trait in cats. The A31P single nucleotide polymorphism (SNP) in the myosin binding protein C 3 gene is thought to be the causative mutation in Maine Coon cats. Additionally, the A74T SNP
C V Hopps et al.
Human reproduction (Oxford, England), 18(8), 1660-1665 (2003-07-23)
Y chromosome microdeletions are associated with severe male factor infertility. In this study, the success rate of testicular sperm retrieval was determined for men with deletions of AZF regions a, b or c. AZF deletions were detected by PCR of
Yu-Heng Vivian Ma et al.
Journal of cellular biochemistry (2018-11-13)
Bone metastases occur in 65% to 75% of patients with advanced breast cancer and significantly worsen their survival and quality of life. We previously showed that conditioned medium (CM) from osteocytes stimulated with oscillatory fluid flow, mimicking bone mechanical loading
E J Heyer et al.
Neurology, 65(11), 1759-1763 (2005-10-07)
Between 9% and 23% of patients undergoing otherwise uncomplicated carotid endarterectomy (CEA) develop subtle cognitive decline 1 month postoperatively. The APOE-epsilon4 allele has been associated with worse outcome following stroke. To investigate the ability of APOE-epsilon4 to predict post-CEA neurocognitive
Aman U Buzdar et al.
The Lancet. Oncology, 14(13), 1317-1325 (2013-11-19)
Neoadjuvant chemotherapy with trastuzumab for patients with HER2-positive breast cancer can produce a pathological complete response in the breast in 30-65% of patients. We investigated the effect of the timing of trastuzumab administration with anthracycline and taxane neoadjuvant chemotherapy. This
S Mokuda et al.
Journal of endocrinological investigation, 35(9), 796-799 (2012-11-09)
The serum undercarboxylated osteocalcin (ucOC) level, a biochemical bone marker of vitamin K insufficiency, is often affected by anti-osteoporosis drugs. There have been no reports regarding the relationship between ucOC and teriparatide. We conducted a prospective observational study of 26
Yuliya Lytvyn et al.
American journal of physiology. Renal physiology, 308(2), F77-F83 (2014-11-08)
Plasma uric acid (PUA) is associated with metabolic, cardiovascular, and renal abnormalities in patients with type 2 diabetes but is less well understood in type 1 diabetes (T1D). Our aim was to compare PUA levels and fractional uric acid excretion
Marc C Chamberlain
Expert review of neurotherapeutics, 12(8), 929-936 (2012-09-26)
One hundred patients, aged 36-84 years (median 62 years) with recurrent glioblastoma (GBM), were treated previously with surgery, concurrent radiotherapy and temozolomide and postradiotherapy temozolomide followed by single-agent bevacizumab (BEV) at either first (60 patients) or second recurrence (40 patients).
Zhanpeng Li et al.
Indian journal of biochemistry & biophysics, 49(3), 165-172 (2012-07-19)
Generally, extra-cellular-signal-regulated kinase 5 (ERK5) signaling pathway regulates many physiological activities, such as cell proliferation and cell differentiation. However, little is known about how ERKS signaling pathway composed of 15 paths participates in regulating hepatocyte proliferation during liver regeneration (LR).
Badr Al-Bawardy et al.
Mayo Clinic proceedings, 89(5), 595-601 (2014-03-26)
To examine the effectiveness and tolerability of triple therapy with pegylated interferon (p-IFN), ribavirin (RBV), and telaprevir in patients with chronic hepatitis C receiving treatment in an academic practice setting and in a more clinically diverse population compared with patients
Brian W Parks et al.
Arteriosclerosis, thrombosis, and vascular biology, 26(12), 2703-2709 (2006-09-23)
Lysophosphatidylcholine is a major product of low-density lipoprotein (LDL) oxidation and secretory phospholipase A2-mediated lipid hydrolysis within atherosclerotic lesions. The G2A receptor mediates chemotaxis of cultured macrophages and T cells to lysophosphatidylcholine, supporting a pro-atherogenic role for this receptor in
E E Hermel et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 34(9), 1191-1195 (2001-08-22)
Neonatal handling has long-lasting effects on behavior and stress reactivity. The purpose of the present study was to investigate the effect of neonatal handling on the number of dopaminergic neurons in the hypothalamic nuclei of adult male rats as part
Tarun Narang et al.
Sexual health, 10(5), 452-455 (2013-09-14)
Red scrotum syndrome (RSS) is not infrequent but is often misdiagnosed or underdiagnosed, and seldom reported. The exact etiopathogeneis is still unknown but it almost always follows the prolonged application of topical corticosteroids and is characterised by persistent erythema of
Soichiro Itoh et al.
Journal of bone and mineral metabolism, 31(2), 206-211 (2012-11-10)
This study was performed to investigate the effects of the co-administration of proton pump inhibitor (PPI) on the efficacy of bisphosphonate (BP) treatment for osteoporosis. A total of 180 women with low bone mineral density were randomly divided into four
André Borsatto Zanella et al.
Thyroid : official journal of the American Thyroid Association, 28(10), 1285-1292 (2018-08-22)
Risk stratification for persistent disease is an important step in pediatric differentiated thyroid cancer (DTC) management. The dynamic risk stratification (DRS) is a well validated system for adults, but not yet for children and adolescents. This study evaluated the DRS
Yanru Zeng et al.
BMC genetics, 15 Suppl 1, S2-S2 (2014-08-01)
Torreya grandis Fort. ex Lindl, a conifer species widely distributed in Southeastern China, is of high economic value by producing edible, nutrient seeds. However, knowledge about the genome structure and organization of this species is poorly understood, thereby limiting the
C Nascimento et al.
European journal of endocrinology, 169(5), 689-693 (2013-08-14)
Thyroglobulin (Tg) measurement is a major tool for the follow-up of differentiated thyroid cancer (DTC) patients; however, in patients who do not undergo radioactive iodine (RAI) ablation, normal ultrasensitive Tg levels measured under levothyroxine treatment (usTg/l-T4) are not well defined.
J Dômont et al.
British journal of cancer, 102(6), 1032-1036 (2010-03-04)
Fibromatosis comprises distinct clinical entities, including sporadic extra-abdominal fibromatosis, which have a high tendency for recurrence, even after adequate resection. There are no known molecular biomarkers of local recurrence. We searched for beta-catenin mutations in a European multicentre series of
Krzysztof Lewandowski et al.
Polskie Archiwum Medycyny Wewnetrznej, 119(12), 789-794 (2009-12-17)
The presence of BCR-ABL oncogene mutations in patients with chronic myeloid leukemia (CML) may be responsible for the failure of tyrosine kinase inhibitor treatment. The aim of the study was to evaluate the frequency of BCR-ABL gene mutations in patients
Nicolás Ramírez-Torres et al.
Cirugia y cirujanos, 81(2), 98-107 (2013-03-26)
association of breast cancer and pregnancy is not common. The objective of this investigation was to evaluate the pregnancy, young age, stage, treatment, prognosis and mortality of women with breast cancer during pregnancy. retrospective analysis from March 1992 to February
Dongfeng Tan et al.
Human pathology, 34(6), 597-604 (2003-06-27)
Thyroid transcription factor 1 (TTF-1), a homeodomain-containing transcription factor, plays a pivotal role in lung development, cell growth, and differentiation processes. The current literature reports considerable variation in frequency of TTF-1 protein expression in human non-small cell lung cancer (NSCLC).
M Moshahid Alam Rizvi et al.
Journal of cancer research and clinical oncology, 137(8), 1255-1262 (2011-06-24)
PTEN, a tumor-suppressor gene located on chromosome 10q23.3 is implicated in multiple tumors including cervical carcinoma. We examined 135 cervical cancer specimens for PTEN gene expression and promoter methylation using methylation-specific PCR and immunohistochemistry and also studied the mutation in
T Vermeire et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(7), 907-907 (2018-12-07)
Mumps used to affect children between 2 and 15 years old. The mumps-measles-rubella (MMR) vaccine is available, with vaccine coverage rate of about 85% after two vaccine doses. Recently new mumps outbreaks have emerged in highly vaccinated populations; the causes for
Edward B Garon et al.
Lancet (London, England), 384(9944), 665-673 (2014-06-17)
Ramucirumab is a human IgG1 monoclonal antibody that targets the extracellular domain of VEGFR-2. We aimed to assess efficacy and safety of treatment with docetaxel plus ramucirumab or placebo as second-line treatment for patients with stage IV non-small-cell-lung cancer (NSCLC)
A Koenig et al.
Veterinary pathology, 38(4), 427-435 (2001-07-27)
We evaluated the expression of vimentin, S100a, and Melan A/MART-1 (melanoma antigen recognized by T cells 1) in seven cell lines established independently from dogs with canine melanoma. We also compared routine immunostaining of 29 clinical specimens from melanoma cases
Patrick H Dessein et al.
Clinical and experimental rheumatology, 33(4), 491-497 (2015-05-13)
We examined the association of TNF-related apoptosis-inducing ligand (TRAIL) concentrations with cardiovascular disease (CVD) in rheumatoid arthritis (RA) and, since osteoprotegerin (OPG) can act as a decoy receptor for TRAIL, whether TRAIL concentrations impact on the OPG level-atherosclerotic CVD relation
Christos Haritoglou et al.
Retina (Philadelphia, Pa.), 26(6), 618-622 (2006-07-11)
To report on long-term results of macular hole surgery with peeling of the internal limiting membrane (ILM) in a prospective nonrandomized study. Sixty-four consecutive patients with a follow-up of at least 36 months were included. Only idiopathic macular holes were
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