Merck
CN
Search Within

62335

Applied Filters:
Keyword:'62335'
Showing 1-30 of 65 results for "62335" within Papers
Seon-Joo Park et al.
Biological trace element research, 151(2), 294-300 (2012-12-04)
This study investigated the anti-obesity effects of Jeju ground water containing the vanadium components S1 (8.0 ± 0.9 μg/l) and S3 (26.0 ± 2.09 μg/l) on the differentiation of 3 T3-L1 preadipocytes and obesity in mice that were fed a
Marie-France Palin et al.
The British journal of nutrition, 111(6), 1011-1020 (2013-11-16)
In the present study, the effect of flax hulls with or without flax oil bypassing the rumen on the expression of lipogenic genes in the mammary tissue of dairy cows was investigated. A total of eight dairy cows were used
Shizuya Yamashita
Nihon rinsho. Japanese journal of clinical medicine, 71(9), 1578-1583 (2013-11-12)
Primary hyperchylomicronemia is characterized by a marked hypertriglyceridemia due to an increase in chylomicrons, which may cause acute pancreatitis and eruptive xanthomas. This entity includes familial lipoprotein lipase (LPL) deficiency, familial apolipoprotein C-II deficiency, primary type V hyperlipoproteinemia, and idiopathic
K Haddley
Drugs of today (Barcelona, Spain : 1998), 49(3), 161-170 (2013-03-26)
Alipogene tiparvovec is the first adeno-associated virus (AAV)-mediated gene therapy to be approved for the treatment of a metabolic disorder. Lipoprotein lipase (LPL) deficiency (LPLD) is a rare autosomal-recessive disorder in which gene mutations cause the production of a catalytically
Guo-Ping Tian et al.
Biochemical and biophysical research communications, 443(2), 428-434 (2013-12-07)
Atherosclerosis is a lipid disorder disease characterized by chronic blood vessel wall inflammation driven by the subendothelial accumulation of macrophages. Studies have shown that lipoprotein lipase (LPL) participates in lipid metabolism, but it is not yet known whether post-transcriptional regulation
Tamara Bozina et al.
Collegium antropologicum, 37(3), 801-808 (2013-12-07)
Peroxisome proliferator activated receptor-gamma (PPARG) and lipoprotein lipase (LPL) play important role in lipid homeostasis, insulin resistance and adipogenesis, and their gene variability could be considered as predictive genetic markers for metabolic syndrome (MetSy). The aim of the study was
Edit Porpaczy et al.
Leukemia research, 37(6), 631-636 (2013-03-13)
In chronic lymphocytic leukaemia (CLL), lipoprotein lipase (LPL) mRNA overexpression is an established poor prognostic marker, its function, however, is poorly understood. Measuring extracellular LPL enzymatic activity and protein, we found no difference between levels in CLL patients and those
Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1
Voss CV, et al.
Proceedings of the National Academy of Sciences of the USA, 108(19), 7980-7984 (2011)
Sumita Jain et al.
Infection and immunity, 81(4), 1277-1286 (2013-02-06)
Infection by the chronic periodontitis-associated pathogen Porphyromonas gingivalis activates a Toll-like receptor 2 (TLR2) response that triggers inflammation in the host but also promotes bacterial persistence. Our aim was to define ligands on the surfaces of intact P. gingivalis cells
Sonja Kallendrusch et al.
PloS one, 7(12), e51208-e51208 (2013-01-04)
The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations. To better understand the mechanism beyond physiological signaling we used Organotypic Entorhino-Hippocampal Slice
C.H. von der Osten et al.
Journal of the American Chemical Society, 111, 3924-3924 (1989)
Human lipoprotein lipase. I. Purification and substrate specificity.
C J Fielding
Biochimica et biophysica acta, 206(1), 109-117 (1970-04-22)
Gene therapy enters the pharma market: the short story of a long journey.
Hildegard Büning
EMBO molecular medicine, 5(1), 1-3 (2013-01-04)
Raffay S Khan et al.
American journal of physiology. Endocrinology and metabolism, 305(11), E1339-E1347 (2013-10-03)
Hearts utilize fatty acids as a primary source of energy. The sources of those lipids include free fatty acids and lipoprotein triglycerides. Deletion of the primary triglyceride-hydrolyzing enzyme lipoprotein lipase (LPL) leads to cardiac dysfunction. Whether heart LPL-knockout (hLPL0) mice
Stephen G Young et al.
Genes & development, 27(5), 459-484 (2013-03-12)
All organisms use fatty acids (FAs) for energy substrates and as precursors for membrane and signaling lipids. The most efficient way to transport and store FAs is in the form of triglycerides (TGs); however, TGs are not capable of traversing
Purified bovine milk (lipoprotein) lipase: activity against lipid substrates in the absence of exogenous serum factors.
T Egelrud et al.
Biochimica et biophysica acta, 306(1), 115-127 (1973-04-13)
Huilin Gong et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 61(12), 857-868 (2013-09-06)
Lipoprotein lipase (LPL) is involved in regulation of fatty acid metabolism, and facilitates cellular uptake of lipoproteins, lipids and lipid-soluble vitamins. We evaluated LPL distribution in healthy and Alzheimer's disease (AD) brain tissue and its relative levels in cerebrospinal fluid.
L-malate-sensing electrode based on malate dehydrogenase and NADH oxidase
F. Mizutani et al.
Analytica Chimica Acta, 245, 145-150 (1991)
Positional specificity of lipoprotein lipase.
N Morley et al.
The Journal of biological chemistry, 247(20), 6389-6393 (1972-10-25)
Maria H Jäntti et al.
Molecular pharmacology, 83(3), 621-632 (2012-12-13)
It has been proposed that OX(1) orexin receptors and CB(1) cannabinoid receptors can form heteromeric complexes, which affect the trafficking of OX(1) receptors and potentiate OX(1) receptor signaling to extracellular signal-regulated kinase (ERK). We have recently shown that OX(1) receptor
Daiji Nagayama et al.
Nihon rinsho. Japanese journal of clinical medicine, 71(9), 1602-1605 (2013-11-12)
In Japan, the frequency of acute pancreatitis is 27.7 per 100,000, which includes 1.4 % of hypertriglyceridemia-induced pancreatitis(HTGP). Severity and complication rates with HTGP have been reported as higher in comparison to acute pancreatitis from other etiologies. Havel has suggested
Sajjad Rafiq et al.
Lipids in health and disease, 11, 155-155 (2012-11-16)
Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is important since it would suggest wider relevance for these findings. Given
David A Baltzegar et al.
The Journal of endocrinology, 220(1), 61-72 (2013-11-07)
Osmoregulation is critical for survival in all vertebrates, yet the endocrine regulation of this metabolically expensive process is not fully understood. Specifically, the function of leptin in the regulation of energy expenditure in fishes, and among ectotherms, in general, remains
Brian C Shonesy et al.
Nature neuroscience, 16(4), 456-463 (2013-03-19)
The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates activity-dependent depression of excitatory neurotransmission at central synapses, but the molecular regulation of 2-AG synthesis is not well understood. Here we identify a functional interaction between the 2-AG synthetic enzyme diacylglycerol lipase-α (DGLα) and calcium/calmodulin
Jessica Lusty Beech et al.
RSC advances, 12(13), 8119-8130 (2022-04-16)
Esterase enzymes catalyze diverse hydrolysis reactions with important biological, commercial, and biotechnological applications. For the improvement of these biocatalysts, there is a need for widely accessible, inexpensive, and adaptable activity screening assays that identify enzymes with particular substrate specificities. Natural
S Valdeolivas et al.
Cell death & disease, 4, e862-e862 (2013-10-19)
The cannabinoid CB2 receptor, which is activated by the endocannabinoid 2-arachidonoyl-glycerol (2-AG), protects striatal neurons from apoptotic death caused by the local administration of malonate, a rat model of Huntington's disease (HD). In the present study, we investigated whether endocannabinoids
Camila C Leança et al.
Cardiovascular diabetology, 12, 173-173 (2013-11-26)
We have searched if plasma high density lipoprotein-cholesterol (HDL-C) concentration interferes simultaneously with whole-body cholesterol metabolism and insulin sensitivity in normal weight healthy adult subjects. We have measured the activities of several plasma components that are critically influenced by insulin
Yong-Woon Ryu et al.
Zoological science, 30(3), 224-237 (2013-03-14)
Large amounts of neutral lipids (NLs) are stored as lipid droplets in the ooplasm of fish oocytes, providing an essential energy resource for developing embryos and larvae. However, little is known about the origin of such lipids or about mechanisms
Jonghan Kim et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(4), 1657-1663 (2012-12-18)
Iron loading is associated with altered lipid metabolism, but underlying mechanisms remain unknown. We compared serum iron and triglycerides (TGs) in Belgrade rats, a genetic model of iron-loading anemia. Homozygous b/b rats had greater serum iron (68 vs. 28 μM;
Takanari Gotoda
Nihon rinsho. Japanese journal of clinical medicine, 71(9), 1558-1564 (2013-11-12)
Rare monogenic and severe hypertriglyceridemia usually results from genetic abnormalities that lead to severely reduced activity of lipoprotein lipase (LPL), a crucial player in the hydrolysis of triglyceride(TG)-rich lipoproteins. These include mutations in the genes for LPL, APOC2, GPIHBP1, LMF1
Page 1 of 3