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Showing 1-30 of 1631 results for "63423" within Papers
Catherine M Buckley et al.
Current biology : CB, 30(15), 2912-2926 (2020-06-13)
Engulfment of extracellular material by phagocytosis or macropinocytosis depends on the ability of cells to generate specialized cup-shaped protrusions. To effectively capture and internalize their targets, these cups are organized into a ring or ruffle of actin-driven protrusion encircling a
Andreas von Bohl et al.
Malaria journal, 14, 435-435 (2015-11-06)
During development in human erythrocytes, Plasmodium falciparum parasites display a remarkable number of adhesive proteins on their plasma membrane. In the invasive merozoites, these include members of the PfMSP1 and PfAMA1/RON complexes, which facilitate contact between merozoites and red blood
Tengchuan Jin et al.
PloS one, 13(1), e0190547-e0190547 (2018-01-03)
NLRP12 is a NOD-like receptor that plays multiple roles in both inflammation and tumorigenesis. Despite the importance, little is known about its mechanism of action at the molecular level. Here, we report the crystal structure of NLRP12 PYD domain at
Xiudan Wang et al.
Fish & shellfish immunology, 70, 308-318 (2017-09-11)
Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domain are both competent immune recognition modules, and the immunological roles of LRR and Ig domain containing- proteins (LRRIGs) are speculated to be multifunctional and worth investigating. In the present study, two novel
Gaetano Cardone et al.
Journal of the science of food and agriculture, 100(6), 2453-2459 (2020-01-19)
Pre-harvest sprouting of wheat is viewed negatively because of the high level of enzymatic activity, which leads to a deterioration in the bread-making performance of the related flours. On the other hand, improvements in bread properties (i.e. volume and crumb
Haifeng Li et al.
Applied biochemistry and biotechnology, 178(6), 1141-1153 (2015-11-29)
UDPG pyrophosphatase (UGPase) plays an important role in carbohydrate metabolism, catalyzing a reversible production of uridine diphosphate glucose (UDPG) and pyrophosphate (PPi) from Glc-1-P and UTP. UGPase gene from Aureobasidium pullulans NRRL Y-12974 was cloned, overexpressed in Escherichia coli. The
Mingquan Xie et al.
Science signaling, 13(643) (2020-08-06)
Two-component systems (TCSs), which consist of a histidine kinase (HK) sensor and a response regulator (RR), are important for bacteria to quickly sense and respond to various environmental signals. HKs and RRs typically function as a cognate pair, interacting only
Eunyoung Jo et al.
Developmental and comparative immunology, 77, 270-279 (2017-09-05)
Dendritic-cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) is a C-type lectin that functions as a pattern recognition receptor by recognizing pathogen-associated molecular patterns (PAMPs). It is also involved in various events of the dendritic cell (DC) life cycle, such as DC migration, antigen
Bonnie L Barrilleaux et al.
PloS one, 9(7), e101151-e101151 (2014-07-02)
The transcription factor Miz-1 can either activate or repress gene expression in concert with binding partners including the Myc oncoprotein. The genomic binding of Miz-1 includes both core promoters and more distal sites, but the preferred DNA binding motif of
Petr Česla et al.
Journal of chromatography. A, 1438, 179-188 (2016-02-26)
In this work, we have investigated retention of maltooligosaccharides and their fluorescent derivatives in hydrophilic interaction liquid chromatography using four different stationary phases. The non-derivatized maltooligosaccharides (maltose to maltoheptaose) and their derivatives with 2-aminobenzoic acid, 2-aminobenzamide, 2-aminopyridine and 8-aminonaphthalene-1,3,6-trisulfonic acid
Desiccation Treatment and Endogenous IAA Levels Are Key Factors Influencing High Frequency Somatic Embryogenesis in
Xiaohong Zhou et al.
Frontiers in plant science, 8, 2054-2054 (2017-12-21)
Bettina Bölter et al.
Photosynthesis research, 145(1), 43-54 (2019-12-23)
The plastid potassium cation efflux antiporters (KEAs) are important for chloroplast function, development, and photosynthesis. To understand their regulation at the protein level is therefore of fundamental importance. Prior studies have focused on the regulatory K+ transport and NAD-binding (KTN)
Li-Hua Zhao et al.
Science (New York, N.Y.), 364(6436), 148-153 (2019-04-13)
The parathyroid hormone receptor-1 (PTH1R) is a class B G protein-coupled receptor central to calcium homeostasis and a therapeutic target for osteoporosis and hypoparathyroidism. Here we report the cryo-electron microscopy structure of human PTH1R bound to a long-acting PTH analog
Hirotatsu Imai et al.
Nucleic acids research, 46(15), 7820-7830 (2018-07-17)
The ATP-binding cassette (ABC) protein ABCE1 is an essential factor in ribosome recycling during translation. However, the detailed mechanochemistry of its recruitment to the ribosome, ATPase activation and subunit dissociation remain to be elucidated. Here, we show that the ribosomal
Pingping Xu et al.
Biotechnology progress, 31(3), 736-743 (2015-03-05)
Plant lectins have displayed a variety of biological activities. In this study, for the first time, a 27 kDa arabinose- and mannose-specific lectin from Broccolini (Brassica oleracea Italica × Alboglabra), named as BL (Broccolini lectin), was purified by an activity-driven
Wenjing Wang et al.
Nature biotechnology, 35(9), 864-871 (2017-06-27)
Activity remodels neurons, altering their molecular, structural, and electrical characteristics. To enable the selective characterization and manipulation of these neurons, we present FLARE, an engineered transcription factor that drives expression of fluorescent proteins, opsins, and other genetically encoded tools only
Shuang Liu et al.
Immunology and cell biology, 92(9), 752-760 (2014-06-18)
The regulated control of Ca(2+) influx is essential for the activation and function of the adaptive immune response, as Ca(2+) is a key regulator of important transcription factors. To determine whether Ca(2+) release-activated Ca(2+) (CRAC) channels contribute to the abnormal
Bagdeser A Ozdilek et al.
Nucleic acids research, 45(13), 7984-7996 (2017-06-03)
RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-binding properties remain poorly understood. Here, we report a detailed analysis of the RNA binding characteristics of intrinsically disordered RGG/RG domains from Fused in
Juri Sadahiro et al.
Biochemical and biophysical research communications, 456(1), 500-505 (2014-12-10)
Gluconobacter oxydans ATCC 11894 produces dextran dextrinase (DDase, EC 2.4.1.2), which synthesizes dextran from the starch hydrolysate, dextrin and is known to cause ropy beer. G. oxydans ATCC 11894 was believed to possess both a secreted DDase (DDext) and an
Dominika Wrobel et al.
Biochimica et biophysica acta, 1848(7), 1490-1501 (2015-04-07)
The influence of maltose-modified poly(propylene imine) (PPI) dendrimers on dimyristoylphosphatidylcholine (DMPC) or dimyristoylphosphatidylcholine/dimyristoylphosphatidylglycerol (DMPC/DMPG) (3%) liposomes was studied. Fourth generation (G4) PPI dendrimers with primary amino surface groups were partially (open shell glycodendrimers - OS) or completely (dense shell glycodendrimers
S T Miller et al.
Plant disease, 103(6), 1138-1147 (2019-04-03)
In western Colorado, Cytospora leucostoma is ubiquitous in peach orchards and has developed into a major limiting factor of peach production. The pathogen is unable to invade healthy intact phloem tissue of the tree, but instead, it requires a wound
Attenuation of postprandial blood glucose in humans consuming isomaltodextrin: carbohydrate loading studies.
Tsuyoshi Sadakiyo et al.
Food & nutrition research, 61(1), 1325306-1325306 (2017-07-01)
Qing Wang et al.
Analytica chimica acta, 854, 191-201 (2014-12-07)
A hydrophilic stationary phase (SP) was prepared through grafting N-methylene phosphonic acid chitosan on magnesia-zirconia particles (P-CTS-MgO-ZrO2) via Lewis acid-base interaction. The resulting material was characterized by thermogravimetric analysis, Fourier transform infrared spectroscopy, scanning electron microscope and nitrogen adsorption analysis.
Role of α-Actinin 2 in Cytoadherence and Cytotoxicity of
Hye-Yeon Lee et al.
Journal of microbiology and biotechnology, 27(10), 1844-1854 (2017-08-26)
Nathan Gumlaw et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 28(2), 664-676 (2019-12-18)
Patients with α-dystroglycanopathies, a subgroup of rare congenital muscular dystrophies, present with a spectrum of clinical manifestations that includes muscular dystrophy as well as CNS and ocular abnormalities. Although patients with α-dystroglycanopathies are genetically heterogeneous, they share a common defect
Simon Gross et al.
Yeast (Chichester, England), 35(10), 559-566 (2018-05-13)
Antagonistic yeasts suppress plant pathogenic fungi by various mechanisms, but their biocontrol efficacy also depends on the ability to compete and persist in the environment. The goal of the work presented here was to quantify the composition of synthetic yeast
Kwang Hoon Sung et al.
Biochemical and biophysical research communications, 453(3), 642-647 (2014-10-12)
When mRNAs lack stop codons, errors in gene expression and coding of aberrant proteins that are harmful in cells can result. In Saccharomyces cerevisiae, a 180-kDa E3-ubiquitin ligase, Ltn1 has been known to associate with ribosomes and marks translationally-arrested aberrant
Laura Ruiz-Aceituno et al.
International journal of food microbiology, 316, 108476-108476 (2019-12-25)
This work aimed to investigate the ability of two human-derived bifidobacterial strains, i.e. Bifidobacterium breve UCC2003 and Bifidobacterium longum NCIMB 8809, to utilize various oligosaccharides (i.e., 4-galactosyl-kojibiose, lactulosucrose, lactosyl-oligofructosides, raffinosyl-oligofructosides and lactulose-derived galacto-oligosaccharides) synthesized by means of microbial glycoside hydrolases.
Wai-Hong Tham et al.
PLoS pathogens, 11(12), e1005343-e1005343 (2015-12-24)
The most severe form of malaria in humans is caused by the protozoan parasite Plasmodium falciparum. The invasive form of malaria parasites is termed a merozoite and it employs an array of parasite proteins that bind to the host cell
Arunprasad Sivaraman et al.
Drug delivery and translational research, 7(1), 16-26 (2016-08-27)
Novel in situ forming hydrogel microneedles were evaluated for transdermal drug delivery using a biocompatible non-ionic triblock amphiphilic thermosensitive copolymer. The transition property of poloxamer from solution at room temperature to gel at skin temperature (32 °C) was utilized in preparation
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