of Improvement
Decreased solvent usage by 80%
Reduced quantity of chemical usage
XPhos (638064)
N/A
N/A
N/A
N/A
0= Most Desirable
50%
Reduced chemical processing
Reduced usage
Kumada-Corriu coupling and α-Arylation of
ketones
• Hydroamination
i -Pr
i -Pr
i -Pr
P
638064
XPhos 564483-18-7 476.72 X X X X X X • Hiyama coupling
• Carbonyl enolate coupling
Cy2P