67-20-9

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Showing 1-30 of 179 results for "67-20-9" within Papers

Ki-67 and MCM-2 in dental follicle and odontogenic cysts: the effects of inflammation on proliferative markers.

Nurhan Güler et al.

TheScientificWorldJournal, 2012, 946060-946060 (2012-07-11)

The aim of this study was to investigate whether there is any association between inflammation and the expression of markers of cell cycle entry (Ki-67 and MCM-2) in dental follicle (DF) of asymptomatic impacted teeth and odontogenic cysts. The study

Challenges in Ki-67 assessments in pulmonary large-cell neuroendocrine carcinomas.

Ann E Walts et al.

Histopathology, 78(5), 699-709 (2020-10-08)

To gather the best available evidence regarding Ki-67% values in large-cell neuroendocrine carcinoma (LCNEC) and determine whether certain cut-off values could serve as a prognostic feature in LCNEC. Aperio ScanScope AT Turbo, eSlide Manager and ImageScope software (Leica Biosystems) were

Activity of pivaloyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony-forming units.

L L Siu et al.

Investigational new drugs, 16(2), 113-119 (1998-12-16)

The anti-proliferative effects of pivaloyloxymethyl butyrate (AN-9), a butyric acid (BA) derivative with potent tumor-differentiating properties both in vitro and in vivo, was evaluated against colorectal, breast, lung, ovarian, renal cell, bladder, and other types of tumor colony-forming units in

The expression of myeloid antigens CD13 and/or CD33 is a marker of ALK+ anaplastic large cell lymphomas.

Ian M Bovio et al.

American journal of clinical pathology, 130(4), 628-634 (2008-09-17)

We retrospectively studied the immunophenotype by flow cytometry of 20 anaplastic large cell lymphomas (ALCLs) (9 anaplastic lymphoma kinase [ALK]+ and 11 ALK-) with a particular emphasis on the aberrant expression of the myeloid associated antigens CD13 and/or CD33. All

Immunohistochemical study of p53, Ki-67, MMP-2 and MMP-9 expression at invasive front of squamous cell and verrucous carcinoma in oral cavity.

Nooshin Mohtasham et al.

Pathology, research and practice, 209(2), 110-114 (2013-01-01)

Squamous cell carcinoma (SCC) is the most common malignancy in the oral cavity. Verrucous carcinoma (VC) is a lower grade subtype of SCC with pathological similarities but different management. Tumor invasive front (TIF) is a dynamic location in the differentiation

Exon 20 PIK3CA mutations decreases survival in aggressive (HER-2 positive) breast carcinomas.

Enrique Lerma et al.

Virchows Archiv : an international journal of pathology, 453(2), 133-139 (2008-08-06)

PIK3CA mutations at 9 and 20 exons were studied in a series of 56 selected aggressive breast carcinomas (BC): 27 with Her-2 over-expression and negativity for estrogen receptors (ER) and progesterone receptors (PR), and 29 "triple negative" BC (negative for

LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization.

Stine H Kresse et al.

Genes, chromosomes & cancer, 48(8), 679-693 (2009-05-15)

Osteosarcomas are the most common primary malignant tumor of bone, and almost all conventional osteosarcomas are high-grade tumors with complex karyotypes. We have examined DNA copy number changes in 36 osteosarcoma tumors and 20 cell lines using microarray-based comparative genomic

Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions.

Toru Amioka et al.

Oncology reports, 11(1), 51-55 (2003-12-05)

Telomerase activity confers immortality to cells through stabilization of chromosomes and contributes to the development of most human cancers. Human telomerase reverse transcriptase (hTERT) is a catalytic subunit of telomerase. Expression of hTERT mRNA has been reported to be correlated

Evaluation of matrix metalloproteinase type IV-collagenases in serum of patients with tumors of the central nervous system.

Serena Ricci et al.

Journal of neuro-oncology, 131(2), 223-232 (2016-10-21)

The basement membrane collagen IV-degrading matrix metalloproteinases -2 and -9 (MMPs) are most often linked to the malignant phenotype of tumor cells by playing a critical role in invasion, metastasis, angiogenesis, and vasculogenesis. We verified the activity of these two

Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma.

Kalu U E Ogbureke et al.

Oncotarget, 3(3), 286-298 (2012-03-14)

Up to 50% of oral squamous cell carcinomas (OSCCs) recur following surgical resections with conventional "histologically-negative" margins. Three members of the SIBLING family of proteins: dentin sialophophoprotein (DSPP); bone sialoprotein (BSP); and osteopontin OPN are upregulated in OSCCs. In this

Molecular genetic and immunophenotypical analysis of Pax6 transcription factor and neural differentiation markers in human fetal neocortex and retina in vivo and in vitro.

B I Verdiev et al.

Bulletin of experimental biology and medicine, 148(4), 697-704 (2010-04-17)

Neurotransplantation of various cells, including heterotransplantation of fetal cerebral stem/progenitor cells into the eye is used in experimental studies of central nervous tissue repair during neurodegeneration. For evaluation of this approach, human fetal (weeks 9-20) stem/progenitor cells of the neocortex

Down-regulation of HLA-A mRNA in peripheral blood mononuclear cell of colorectal cancer.

Ming-Chen Zhu et al.

International journal of colorectal disease, 27(1), 31-36 (2011-09-29)

It has been demonstrated that the alteration of human leukocyte antigen (HLA) class I expression frequently occurs in colorectal tumor. Previous studies mainly focused on the expression of HLA-A in tumor cells. The expression of HLA-A in peripheral blood mononuclear

Advanced colorectal carcinomas measuring 20 mm or less exhibit markedly higher invasiveness despite their size.

Yasuhiro Kunii et al.

Digestive diseases and sciences, 49(11-12), 1899-1905 (2005-01-05)

To analyze the biology of small (20 mm or less) advanced colorectal carcinomas (SAC), 24 cases, 22 small early colorectal carcinomas (SEC) of similar size, and 52 advanced colorectal carcinomas (AC) were studied. The proliferative (Ki-67) labeling index for SAC

Pembrolizumab monotherapy in patients with previously treated metastatic high-grade neuroendocrine neoplasms: joint analysis of two prospective, non-randomised trials.

Namrata Vijayvergia et al.

British journal of cancer, 122(9), 1309-1314 (2020-03-11)

Metastatic high-grade neuroendocrine neoplasms (G3NENs) have limited treatment options after progression on platinum-based therapy. We addressed the role of Pembrolizumab in patients with previously treated metastatic G3NENs. Two open-label, phase 2 studies enrolled patients with G3NEN (Ki-67 > 20%) to receive Pembrolizumab

[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma].

Wenping Guo et al.

Zhonghua fu chan ke za zhi, 37(10), 604-607 (2002-12-19)

To study the expression of matrix metalloproteinase (MMP)-2, 9 and tissue inhibitor of metalloproteinase (TIMP)-1, 2 protein in human endometrial carcinoma tissue and its relation to the invasion and metastasis of endometrial carcinoma. Immunocytochemistry and zymography techniques were used to

A presurgical window-of-opportunity study of metformin in obesity-driven endometrial cancer.

Vanitha Sivalingam et al.

Lancet (London, England), 385 Suppl 1, S90-S90 (2015-08-28)

Metformin use is associated with reduced cancer risk in several observational studies of patients with type 2 diabetes. Results from preclinical studies in endometrial cancer show that metformin reduces cellular proliferation by inhibition of the PI3K-AKT-mTOR pathway. We tested the

Clusterin expression in cutaneous CD30-positive lymphoproliferative disorders and their histologic simulants.

Stephen H Olsen et al.

Journal of cutaneous pathology, 36(3), 302-307 (2009-02-18)

Clusterin is a ubiquitous 80 kDa heterodimeric glycoprotein previously shown to be expressed on tumor cells of systemic and, to a lesser extent, primary cutaneous anaplastic large cell lymphoma (PC-ALCL). Lymphomatoid papulosis (LyP), an important differential diagnosis of ALCL, has

Long-Term Follow-Up Evaluation of 68 Patients with Uveal Melanoma Liver Metastases Treated with Isolated Hepatic Perfusion.

Ilan Ben-Shabat et al.

Annals of surgical oncology, 23(4), 1327-1334 (2015-12-03)

This report describes the outcomes and long-term follow-up data from all isolated hepatic perfusions (IHPs) performed at a single institution in Sweden between the years 1989 and 2013 for patients with isolated uveal melanoma metastases. A total of 68 patients

Gemcitabine and carboplatin in the treatment of transitional cell carcinoma of the urothelium: a single centre experience and review of the literature.

E Hudson et al.

European journal of cancer care, 19(3), 324-328 (2009-11-17)

The objectives of this study are to evaluate patient outcomes in clinical practice using gemcitabine and carboplatin (GCarbo) as first-line treatment in metastatic transitional cell carcinoma (TCC) of the urothelium, and to review the published evidence on the use of

BRAF mutation in endometrial carcinoma and hyperplasia: correlation with KRAS and p53 mutations and mismatch repair protein expression.

Yu-Zhen Feng et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 11(17), 6133-6138 (2005-09-08)

Although several gene abnormalities have been reported in endometrial carcinoma, the genetic alterations have not fully been elucidated. Recent studies have revealed frequent activating mutations of the gene for BRAF, an effector of Ras protein in the mitogen-activated protein kinase

Evaluation of changes of biologic markers ER, PR, HER 2 and Ki-67 in breast cancer with administration of neoadjuvant dose-dense doxorubicin, cyclophosphamide followed by paclitaxel.

D S Dede et al.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 18(1), 57-63 (2013-04-25)

To assess the changes of biologic markers estrogen receptors (ER), progesterone receptors (PR), HER 2 and Ki-67 in locally advanced breast cancer patients after neoadjuvant chemotherapy. Data from 63 locally advanced breast cancer patients (stage II or III), whose histological

Superoxide dismutase mutations in an unselected cohort of Scottish amyotrophic lateral sclerosis patients.

C T Jones et al.

Journal of medical genetics, 32(4), 290-292 (1995-04-01)

Mutations in the Cu/Zn superoxide dismutase (SOD1) gene are responsible for some cases of familial amyotrophic lateral sclerosis (ALS). We have shown that SOD1 mutations can also occur in apparently sporadic ALS. To establish how often this happens we have

Umbilical cord serum erythropoietin levels and maternal smoking in pregnancy.

Soner Sazak et al.

TheScientificWorldJournal, 2012, 420763-420763 (2012-05-25)

To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%)

Carcinoid tumors of the duodenum and ampulla of vater: a clinicomorphologic, immunohistochemical, and cell kinetic comparison.

L Bornstein-Quevedo et al.

Human pathology, 32(11), 1252-1256 (2001-12-01)

Carcinoid tumors of the ampulla of Vater (ACs) differ from duodenal carcinoid tumors (DCs). A search for AC and DC was made between 1980 and 2000. The clinicopathologic features and follow-up were assessed. Immunohistochemistry for panneuroendocrine markers, hormone products, proliferating

The role of apoptosis in pituitary adenomas in the field of conventionally used therapeutic approaches.

Jaroslav Cerman et al.

Annals of the New York Academy of Sciences, 1010, 520-524 (2004-03-23)

The aim of the study was to investigate the mechanism of action of somatostatin analogues (SSA), ionizing radiation, and their combination on pituitary adenoma cells with special emphasis on proliferative and apoptotic activity. In the 14 GH-secreting adenomas pretreated with

Lycopene counteracts the hepatic response to 7,12-dimethylbenz[a]anthracene by altering the expression of Bax, Bcl-2, caspases, and oxidative stress biomarkers.

Can Ali Agca et al.

Pharmaceutical biology, 50(12), 1513-1518 (2012-09-18)

Lycopene is a carotenoid found in tomato, watermelon, pink grapefruit, and guava in high concentration. Dietary intake of lycopene has been proposed to inversely correlate with the risk of cancer. It has also been reported to provide protection against cellular

Microvascularization and expression of VEGF and its receptors in recurring meningiomas: pathobiological data in favor of anti-angiogenic therapy approaches.

Matthias Preusser et al.

Clinical neuropathology, 31(5), 352-360 (2012-05-01)

We studied expression of molecules of the vascular endothelial growth factor (VEGF) pathway and its relation to vascularization, cell proliferation and patient outcome in recurring non-anaplastic meningioma. We studied 29 tumor specimens of 8 patients with recurring meningiomas and of

Prevalence of groups A and C rotavirus antibodies in infants with biliary atresia and cholestatic controls.

Maria Grazia Clemente et al.

The Journal of pediatrics, 166(1), 79-84 (2014-12-03)

To analyze the prevalence of acute asymptomatic group A and C rotavirus (RV-A and RV-C) infection in neonates with cholestasis. Participants were infants <180 days of age with cholestasis (serum direct or conjugated bilirubin >20% of total and ≥2 mg/dL)

Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients.

Jinhyun Kim et al.

Clinical therapeutics, 31(12), 2860-2872 (2010-01-30)

S-adenosylmethionine (SAMe) has antiinflammatory and analgesic effects and has been reported to ameliorate the pain and dysfunction of osteoarthritis (OA). The metabolism of SAMe can be affected by geographic or ethnic factors. However, its efficacy and tolerability versus NSAIDs have

Primary cutaneous small/medium CD4+ T-cell lymphomas: a heterogeneous group of tumors with different clinicopathologic features and outcome.

Adriana Garcia-Herrera et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26(20), 3364-3371 (2008-06-11)

To define the clinical and pathologic characteristics of primary cutaneous small/medium CD4(+) T-cell lymphoma (PCSM-TCL) and identify parameters of prognostic significance. We have investigated 24 patients with primary cutaneous lymphomas composed of small/medium mature T-cells with a betaF1, CD3, CD4(+)

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