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Showing 1-30 of 83 results for "67-68-5" within Papers
Valentina Ambrosini et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(12), 1843-1848 (2015-09-26)
This study was performed to investigate the role of (68)Ga-DOTANOC SUVmax as a potential prognostic factor in patients with pancreatic neuroendocrine tumor (pNET). Among the patients who underwent (68)Ga-DOTANOC PET/CT, we retrospectively collected the data of those who had G1
L Bodei et al.
European journal of nuclear medicine and molecular imaging, 42(9), 1341-1352 (2015-05-08)
Precise determination of neuroendocrine tumor (NET) disease status and response to therapy remains a rate-limiting concern for disease management. This reflects limitations in biomarker specificity and resolution capacity of imaging. In order to evaluate biomarker precision and identify if combinatorial
Constantinos T Sofocleous et al.
Annals of surgical oncology, 19(13), 4262-4269 (2012-07-04)
To assess the predictive value of examinations of tissue adherent to multitined electrodes on local tumor progression-free survival (LPFS) and overall survival (OS) after liver tumor radiofrequency ablation (RFA). An institutional review board-approved, Health Insurance Portability and Accountability Act-compliant review
Vijay Kumar et al.
Nuclear medicine and biology, 38(3), 393-398 (2011-04-16)
(67)Ga citrate has been extensively used to detect infection and inflammation since 1971. However, its clinical utility is compromised due to several limitations. The present project explored whether (68)Ga-apo-transferrin ((68)Ga-TF), when prepared in vitro, is a useful agent for positron
Methylation of promoter region in p27 gene plays a role in the development of lymphoid malignancies.
Shin-Ichi Nakatsuka et al.
International journal of oncology, 22(3), 561-568 (2003-02-13)
p27 belong to the cyclin-dependent kinase inhibitor family and plays an important role in regulation of cell cycle progression. Expression of these genes is epigenetically suppressed by methylation of their promoter regions. In this study, we examined protein expression and
Ipatia A Doussis-Anagnostopoulou et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(6), 1759-1766 (2008-03-19)
To correlate the immunohistochemical expression of topoisomerase IIalpha (topoIIalpha) in Hodgkin's lymphoma (HL) with clinicopathological parameters, the expression of Ki-67 and the outcome of patients, who had been homogenously treated with ABVD or equivalent regimens. Immunohistochemistry using the monoclonal antibody
Misa Yamamoto et al.
DNA sequence : the journal of DNA sequencing and mapping, 16(6), 474-478 (2005-11-17)
We have determined the cDNA sequence encoding bovine mitochondrial ATP-dependent Lon protease. Since the 5'-end region of the cDNA was highly GC-rich and thus could not be amplified by the 5'-RACE method, a genomic DNA fragment containing an in-frame ATG
Wei Zou et al.
Journal of virology (2021-05-07)
Parvovirus B19 (B19V) infection causes diseases in humans ranging from the mild erythema infectiosum to severe hematological disorders. The unique region of the minor structural protein VP1 (VP1u) of 227 amino acids harbors strong neutralizing epitopes which elicit dominant immune
Yunpeng Cai et al.
The journal of gene medicine, 20(7-8), e3025-e3025 (2018-05-26)
Antisense gapmer oligonucleotide drugs require delivery and biodistribution enabling technologies to increase in vivo efficacy. An attractive approach is their binding and consequent transport by the endogenous human serum albumin pool as mediated by fatty acid incorporation into the gapmer
Demet Acikalin et al.
Tumori, 98(3), 344-350 (2012-07-25)
To evaluate the clinical significance of maspin and Ki-67 expression in patients with newly diagnosed T1 bladder cancer. Maspin and Ki-67 expression was investigated by immunohistochemistry from paraffin-embedded tissues of 68 patients undergoing transurethral resection for bladder cancer. Clinicopathological data
Suzanne C Edavettal et al.
The Journal of biological chemistry, 279(24), 25789-25797 (2004-04-03)
Heparan sulfate interacts with antithrombin, a protease inhibitor, to regulate blood coagulation. Heparan sulfate 3-O-sulfotransferase isoform 1 performs the crucial last step modification in the biosynthesis of anticoagulant heparan sulfate. This enzyme transfers the sulfuryl group (SO(3)) from 3'-phosphoadenosine 5'-phosphosulfate
Benjamin Saltman et al.
Surgery, 140(6), 899-905 (2006-12-26)
Genetic screening studies suggest that genetic changes underlie progression from well differentiated to anaplastic thyroid cancers. The aim of this study is to determine to what extent cell cycle/apoptosis regulators contribute to cancer progression. Tissue microarrarys (TMAs) were constructed from
Junki Endo et al.
Anticancer research, 32(9), 3939-3947 (2012-09-21)
The acute antiemetic effect was compared between oral azasetron and intravenous granisetron based on the 5-hydroxytryptamine(3) (5-HT(3)) receptor occupancy theory. Receptor occupancy was estimated from reported data on plasma concentrations and affinity constants to 5-HT(3) receptor. A randomized non-inferiority study
Sara Massironi et al.
Endocrine, 58(2), 360-367 (2017-02-18)
Small-intestine neuroendocrine neoplasms are heterogeneous neoplasms arising from endocrine cells of the intestinal mucosa. Ki-67 is the main determinant of prognosis in neuroendocrine neoplasms. However, the search for new prognostic makers represents a key point with regard to small-intestine neuroendocrine
Hsiang-Yu Lin et al.
Journal of inherited metabolic disease, 33(5), 619-624 (2010-09-08)
Newborn screening for Fabry disease in Taiwan Chinese has revealed a high incidence of the late-onset GLA mutation IVS4 + 919G→A (∼1 in 1,500-1,600 males). We studied 94 adults with this mutation [22 men, 72 women; mean age: men 57.8 ± 6.0 (range 42-68)
T Kimura et al.
Journal of medicinal chemistry, 36(11), 1641-1653 (1993-05-28)
In our continuing search to find systemically bioavailable ACAT (acyl-CoA:cholesterol O-acyltransferase) inhibitors with more potent antiatherosclerotic effect than N-[2-(dimethylamino)-6-[3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy] phenyl]-N'-pentylurea (3), a series of phenylureas linked to 4-phenylimidazole were synthesized and evaluated for in vitro inhibitory activity toward both aortic
E Rothermel et al.
Biochimica et biophysica acta, 1351(1-2), 9-12 (1997-03-20)
For bacterial expression of rat anaphylatoxin C5a, the cDNA was amplified by reverse transcriptase-polymerase chain reaction (RT-PCR) using rat liver RNA and degenerate primers designed according to the published amino acid sequence [1]. Surprisingly, the amino acid sequence deduced from
Brian J Gebhardt et al.
American journal of clinical oncology, 37(6), 535-538 (2013-02-23)
To evaluate the efficacy of definitive radiotherapy (RT) for the treatment of base of the tongue cancer in a private practice. We retrospectively reviewed the medical records of 48 patients with squamous cell carcinoma of the base of the tongue
Chang Hee Jung et al.
Clinical endocrinology, 77(5), 699-706 (2012-01-04)
The ratio of apolipoprotein B (apoB) to apolipoprotein A1 (apoA1) has been reported to be associated with the metabolic syndrome (MetS). However, the optimal cut-off value of apoB/A1 ratio for detecting subjects with MetS has remained undetermined. In the present
C Bark et al.
Molecular and cellular biology, 5(5), 943-948 (1985-05-01)
Four loci for human U4 RNA have been characterized by DNA sequence analysis. The results show that all four loci represent pseudogenes, which are flanked by direct repeats. Three of the pseudogenes, designated U4/5, U4/6, and U4/8, have very similar
Steven F Dobrowolski et al.
Journal of human genetics, 54(6), 335-339 (2009-05-16)
Phenylketonuria (PKU) is an autosomal recessive defect in hepatic metabolism of phenylalanine, which is secondary to mutations in the phenylalanine hydroxylase (PAH) gene. Sixty-seven ethnically Polish PKU patients, followed at the Outpatient Department of Pediatrics and Developmental Medicine in Poznan
Eric Faudry et al.
The Journal of biological chemistry, 279(19), 19607-19613 (2004-02-27)
Apyrases are nucleoside triphosphate-diphosphohydrolases (EC 3.6.1.5) present in a variety of organisms. The apyrase activity found in the saliva of hematophagous insects is correlated with the prevention of ADP-induced platelet aggregation of the host during blood sucking. Purification of apyrase
Silvia Calabuig-Fariñas et al.
International journal of surgical pathology, 19(4), 448-461 (2011-03-24)
Gastrointestinal stromal tumors (GISTs) are c-KIT-signaling-driven mesenchymal tumors of the human digestive tract, many of which have c-KIT or PDGFRα activating mutations. The authors studied the immunohistochemical markers, c-KIT and PDGFRα mutations, in GISTs and their association with the clinicopathological
Li-Jie Han et al.
British journal of haematology, 179(1), 120-130 (2017-07-25)
We retrospectively investigated outcomes of haploidentical donor (HID) transplant for adults with standard-risk acute lymphoblastic leukaemia (ALL) in first complete remission (CR1) compared with human leucocyte antigen (HLA)-matched sibling donor (MSD) and HLA-matched unrelated donor (MUD) transplants. A total of
S K Ghosh et al.
The Journal of biological chemistry, 266(23), 15293-15299 (1991-08-15)
2'-5'-oligoadenylate synthetases constitute a multimember family of interferon-inducible enzymes which need double-stranded RNA as an obligatory cofactor. We have isolated cDNA clones for two new murine synthetases. These two clones, 9-2 and 3-9, encoded proteins of 414 and 363 amino
T Wada et al.
The Journal of biological chemistry, 274(24), 17353-17357 (1999-06-08)
Cysteine mutagenesis and surface labeling has been used to define more precisely the transmembrane spans of subunit a of the Escherichia coli ATP synthase. Regions of subunit a that are exposed to the periplasmic space have been identified by a
Yong Chen et al.
Journal of surgical oncology, 106(2), 162-168 (2012-02-03)
The role of adjuvant chemotherapy (AC) in treatment of synovial sarcoma remains controversial. Aim of our study is to investigate the influence of AC on disease-specific survival and metastasis free survival, the difference in time to metastasis (TTM) was also
G F Hu et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(6), 2227-2231 (1991-03-15)
A 42-kDa bovine protein that binds bovine angiogenin [angiogenin binding protein (AngBP)] has been identified as a dissociable cell-surface component of calf pulmonary artery endothelial cells and a transformed bovine endothelial cell line, GM7373. Binding of 125I-labeled bovine angiogenin (125I-Ang)
J C Fiddes et al.
Journal of molecular and applied genetics, 1(1), 3-18 (1981-01-01)
The gene encoding the common alpha subunit of the four human glycoprotein hormones, chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), has been cloned in a bacteriophage lambda vector. Restriction endonuclease digestion of
J Trapman et al.
The Journal of general virology, 69 ( Pt 1), 67-75 (1988-01-01)
A mouse interferon alpha gene (MuIFN-alpha 10) was isolated from a BALB/c cosmid genomic library. The gene was located on a 1.8 kb HindIII fragment and a 5.1 kb EcoRI fragment. The coding region and parts of the 5' and
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