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Showing 31-60 of 124 results for "71-43-2" within Papers
Michael Mendelson et al.
Pediatric diabetes, 12(3 Pt 2), 219-228 (2011-03-25)
Children who are born to mothers with pediatric-onset type 2 diabetes mellitus are exposed to a hyperglycemic intra-uterine environment throughout pregnancy. The growth patterns and risk of type 2 diabetes in these offspring may be influenced by unique gene-environment interactions
Frederik Persson et al.
Diabetes research and clinical practice, 96(1), 84-89 (2012-01-03)
We determined levels of the inflammatory marker YKL-40 in a population of patients with type 2 diabetes (T2D) and investigated the association with mortality. In a prospective observational follow-up study, 290 patients with T2D, normoalbuminuria (n=177), microalbuminuria (n=71) and macroalbuminuria
Frank I Tarazi et al.
Psychopharmacology, 198(1), 103-111 (2008-02-26)
The novel psychopharmacologic agent, asenapine, has high affinity for a range of receptors including the dopaminergic receptors. We examined the long-term effects of multiple doses of asenapine on dopamine receptor subtypes: D(1)-like (D(1) and D(5)), D(2), D(3), and D(4). Rats
R Gershoni-Baruch et al.
European journal of cancer (Oxford, England : 1990), 36(18), 2313-2316 (2000-11-30)
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with reduced enzyme activity, hyperhomocysteinaemia and increased risk for atherosclerosis in homozygotes. We examined the frequency of this mutation and its association with disease pattern in 491 Jewish women
Anna E Stanhewicz et al.
Clinical science (London, England : 1979), 129(2), 159-167 (2015-03-10)
Older adults have reduced vascular endothelial function, evidenced by attenuated nitric oxide (NO)-dependent cutaneous vasodilatation. Folic acid and its metabolite, 5-methyltetrahydrofolate (5-MTHF), are reported to improve vessel function. We hypothesized that (i) local 5-MTHF administration and (ii) chronic folic acid
Khadija Ouguerram et al.
Arteriosclerosis, thrombosis, and vascular biology, 32(6), 1520-1525 (2012-03-24)
Anderson disease is a rare inherited lipid malabsorption syndrome associated with hypocholesterolemia and linked to SAR1B mutations. The aim of this article was to analyze the mechanisms responsible for the low plasma apolipoprotein Apo-B100 and Apo-AI in 2 patients with
Matthew G Mei et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 23(11), 1861-1869 (2017-07-25)
High-dose therapy followed by autologous stem cell transplantation (ASCT) can improve outcomes for mantle cell lymphoma (MCL) but is associated with a high incidence of relapse. A retrospective study of 191 MCL patients who underwent ASCT at City of Hope
Stephan W Jahn et al.
The American journal of pathology, 186(1), 15-23 (2016-01-01)
Usual ductal hyperplasia (UDH) of the breast is generally regarded as a nonneoplastic proliferation, albeit loss of heterozygosity has long been reported in a part of these lesions. To gain deeper insights into the molecular drivers of these lesions, an
Sylwia Chojnowska et al.
Disease markers, 2018, 1760592-1760592 (2018-07-22)
Analysis of the correlation between diabetes type 2 (DT2) and serum N-acetyl-β-hexosaminidase (HEX) activity with parameters of fat metabolism and symptoms of anxiety and depression. The study was performed using a random sample of 40 DT2 patients (22 women and
D Reinhardt et al.
Klinische Padiatrie, 224(6), 372-376 (2012-07-24)
The survival rate of children and adolescents suffering acute myeloid leukemia (AML) has been significantly improved within the last decades. This has been achieved by a continuously intensified therapy and progress in supportive care to prevent and treat complications. In
Cinzia Azzoni et al.
Virchows Archiv : an international journal of pathology, 458(5), 525-536 (2011-03-30)
HER-2/neu overexpression and/or gene amplification occurs in several human malignancies, frequently correlates with tumor aggressiveness, and provides the basis for treatment with trastuzumab. Among neuroendocrine neoplasms (NEN) of the gastroenteropancreatic (GEP) tract, ileal neuroendocrine tumors show peculiar features of malignancy
Xin Mao et al.
Blood, 101(4), 1513-1519 (2002-10-24)
Primary cutaneous lymphomas (PCLs) represent a heterogeneous group of extranodal T- and B-cell malignancies. The underlying molecular pathogenesis of this malignancy remains unclear. This study aimed to characterize oncogene abnormalities in PCLs. Using genomic microarray, we detected oncogene copy number
K Luotola et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 109(6), 454-460 (2001-08-17)
Subacute granulomatous thyroiditis (SAT) is a self-limiting systemic inflammatory disorder with possible transient expression of thyroid antibodies. Persistent hypothyroidism is uncommon. The interleukin-1 receptor antagonist IL-1ra is an inhibitor of IL-1 activity and allele 2 of the IL-1ra gene is
Balaiya Velmurugan et al.
Neoplasia (New York, N.Y.), 12(1), 95-102 (2010-01-15)
Chemopreventive effects and associated mechanisms of grape seed extract (GSE) against intestinal/colon cancer development are largely unknown. Herein, we investigated GSE efficacy against intestinal tumorigenesis in APC(min/+) mice. Female APC(min/+) mice were fed control or 0.5% GSE (wt/wt) mixed AIN-76A
H Hara et al.
Nihon Naibunpi Gakkai zasshi, 64(10), 1038-1050 (1988-10-20)
We studied the secretion capacity of TSH-beta in 63 patients with various pituitary disorders, carrying out the observation of TSH-beta changes after TRH administration. Serum TSH-beta concentrations were measured by radioimmunoassay according to the modified method of Kourides. Serum TSH
Antonio R Lucena-Araujo et al.
British journal of haematology, 166(4), 540-549 (2014-05-07)
The KMT2E (MLL5) gene encodes a histone methyltransferase implicated in the positive control of genes related to haematopoiesis. Its close relationship with retinoic acid-induced granulopoiesis suggests that the deregulated expression of KMT2E might lead acute promyelocytic leukaemia (APL) blasts to
K Miwa et al.
Heart and vessels, 6(2), 96-101 (1991-01-01)
In order to examine both the sensitivity and specificity of coronary artery spasm induced by intracoronary injection of acetylcholine in patients with vasospastic angina, incremental doses of acetylcholine (20, 30, and 50 micrograms) were injected directly into each coronary artery
Denis E Corpet et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 12(5), 391-400 (2003-05-17)
The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D.
Suzanne K Jadico et al.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 10(6), 521-527 (2006-12-26)
Apert syndrome, a disorder of craniosynostosis, syndactyly, and other craniofacial malformations, is caused by point mutations (Ser252Trp or Pro253Arg) in the fibroblast growth factor receptor 2 gene. This study's goal was to determine ophthalmic phenotype/genotype correlations in patients with either
Tanzeela Khalid et al.
PloS one, 10(11), e0143283-e0143283 (2015-11-26)
The aim of this work was to investigate volatile organic compounds (VOCs) emanating from urine samples to determine whether they can be used to classify samples into those from prostate cancer and non-cancer groups. Participants were men referred for a
Pablo Barreiro et al.
The Journal of infectious diseases, 203(11), 1629-1636 (2011-05-20)
Single-nucleotide polymorphisms (SNPs) near the IL28B gene have recently been associated with spontaneous hepatitis C virus (HCV) clearance and response to interferon-based therapies in patients with chronic hepatitis C. Because human immunodeficiency virus (HIV) coinfection appears to accelerate HCV-related liver
Giovenzio Genestreti et al.
Technology in cancer research & treatment, 14(6), 721-727 (2014-06-20)
Chemo-radiotherapy is standard treatment of stage IIIA-N2 bulky or IIIB non-small cell lung cancer (NSCLC). Surgical resection of residual disease in downstaged patients may improve overall survival. In this setting, restaging disease is still a challenge. 18F-FDG PET/CT represents the
J A M A Tan et al.
Clinical and experimental medicine, 4(3), 142-147 (2004-12-16)
Beta-thalassemia is the most-common genetic disorder of hemoglobin synthesis in Malaysia, and about 4.5% of the population are heterozygous carriers of the disorder. Prenatal diagnosis was performed for 96 couples using the Amplification Refractory Mutation System and Gap-Polymerase Chain Reaction.
Edi Vaisbuch et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 22(10), 905-916 (2009-07-16)
Fragment Bb is an activator of the alternative pathway of the complement system. Recently, increased first trimester maternal plasma concentrations of this fragment were reported in patients destined to have a spontaneous preterm delivery before 34 weeks of gestation. The
Bärbel Stecher et al.
Infection and immunity, 74(9), 5047-5057 (2006-08-24)
Salmonella enterica subspecies 1 serovar Typhimurium is an enteric bacterial pathogen infecting a broad range of hosts. In susceptible Nramp1(-/-) (Slc11alpha1(-/-)) mice, serovar Typhimurium cannot efficiently colonize the intestine but causes a systemic typhoid-like infection. However, after pretreatment with streptomycin
Hriday P Bhambhvani et al.
Neuroreport, 27(3), 145-150 (2015-12-23)
Schizophrenia is a severe psychiatric disorder that is characterized by a wide array of symptoms and a complex neuropathology. A well-characterized neurobiological feature of schizophrenia is abnormal synaptic plasticity, although the mechanisms underlying this are not fully understood. Numerous studies
L J Chartrand et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 157(5), 527-533 (1997-09-19)
To test the effectiveness of serologic antigliadin antibody (AGA) testing in predicting celiac disease in children. Prospective clinical assessment. Hôpital Sainte-Justine, montreal. A total of 176 children with possible celiac disease who were referred for duodenal biopsy between January 1992
Hans Jürgen Solinski et al.
The Journal of biological chemistry, 287(49), 40956-40971 (2012-10-18)
Sensory neuron-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are primate-specific proteins that are exclusively expressed in primary sensory neurons and provoke pain in humans. Hence, MRGPR-X1 represent promising targets for future pain therapy, but signaling pathways activated by MRGPR-X1 are poorly
Mohammed Z Haque et al.
Hypertension (Dallas, Tex. : 1979), 43(2), 335-340 (2004-01-14)
To determine the role of endogenous superoxide (O2-) in the kidney, we assessed renal hemodynamics and excretory function in gp91(PHOX) (a NAD(P)H oxidase subunit) gene knockout (KO) mice and compared these findings with those of wild-type (WT) strain C57BL/6 mice.
Alessandro Vitale et al.
Journal of hepatology, 62(3), 617-624 (2014-12-03)
The role of hepatic resection for hepatocellular carcinoma (HCC) in different Barcelona Clinic Liver Cancer (BCLC) stages is controversial. We aimed at measuring the survival benefit of resection vs. non-surgical-therapies in each BCLC stage. Using the ITA.LI.CA database, we identified
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