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Showing 61-90 of 124 results for "71-43-2" within Papers
Haidong Zhu et al.
Journal of hypertension, 21(1), 87-95 (2003-01-25)
Genetic variability in the gene for aldosterone synthase--a key enzyme in the production of aldosterone--can affect sodium homeostasis and thereby blood pressure. The possibility of impaired aldosterone production for the development of hypertension is of particular relevance in black Afro-Caribbeans
Hans Jürgen Solinski et al.
The Journal of biological chemistry, 287(49), 40956-40971 (2012-10-18)
Sensory neuron-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are primate-specific proteins that are exclusively expressed in primary sensory neurons and provoke pain in humans. Hence, MRGPR-X1 represent promising targets for future pain therapy, but signaling pathways activated by MRGPR-X1 are poorly
Jae-Ho Yoon et al.
American journal of hematology, 88(12), 1074-1081 (2013-08-29)
Several criteria to define fitness for induction chemotherapy in elderly acute myeloid leukemia (AML) have been proposed; however, no studies have reported outcomes according to the application of a risk-adapted approach. We treated 256 consecutive patients with elderly AML (≥60
H Kleiber et al.
Diabete & metabolisme, 18(2), 84-90 (1992-03-01)
The present work was planned to study the effects of changes in lipid metabolism irrespective of FFA concentrations (FFA) on the regulation of oxidative and nonoxidative disposal of a glucose infusion during hyperinsulinaemia. Fifteen normal volunteers participated in the 3
Giandomenico Passavanti et al.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 81(4), 242-244 (2010-07-09)
The better knowledge concerning the anatomo-physiology of erection has brought important changes to the management of priapism. We experimented with a staged therapeutic protocol forthis condition. 17 patients, aged from 27 to 71 (mean age 43) were treated for ischemic
C Sun et al.
Protein science : a publication of the Protein Society, 6(2), 383-390 (1997-02-01)
Human glutaredoxin is a member of the glutaredoxin family, which is characterized by a glutathione binding site and a redox-active dithiol/disulfide in the active site. Unlike Escherichia coli glutaredoxin-1, this protein has additional cysteine residues that have been suggested to
J Tuokko et al.
Arthritis and rheumatism, 44(2), 315-322 (2001-03-07)
To further characterize the HLA gene products that play an important role in the pathogenesis of rheumatoid arthritis (RA). One hundred thirty-four haplotypes from 67 Finnish RA patients and 77 control haplotypes were analyzed for HLA-DRB1 loci, associated alleles of
Sandra Stoppelkamp et al.
Journal of neuroscience methods, 194(1), 132-138 (2010-10-19)
The cultivation of pure neuronal cultures is considered advantageous for the investigation of cell-type specific responses (such as transmitter release and also pharmacological agents), however, divergent results are a likely consequence of media modifications and culture composition. Using Fura-2 based
David F Heigener et al.
Lung cancer (Amsterdam, Netherlands), 74(2), 274-279 (2011-03-29)
Erlotinib is a highly potent inhibitor of epidermal growth factor receptor tyrosine-kinase activity that significantly prolongs overall survival in patients with non-small-cell lung cancer (NSCLC), and improves symptom control and quality of life compared with placebo. The safety and efficacy
Vita Birzniece et al.
European journal of endocrinology, 172(1), 21-28 (2014-10-19)
To compare estimates by bioimpedance spectroscopy analysis (BIS) of extracellular water (ECW), fat mass (FM), and fat-free mass (FFM) against standard techniques of bromide dilution and dual energy X-ray absorptiometry (DXA) during intervention that causes significant changes in water compartments
Manuel Martin-Flores et al.
Veterinary anaesthesia and analgesia, 39(4), 385-389 (2012-05-31)
To evaluate the potency and duration of three subparalyzing doses of vecuronium (VEC) in isoflurane-anesthetized horses. Prospective experimental study. Thirteen healthy adult horses undergoing arthroscopic surgery. During isoflurane anesthesia, horses received one of three doses of vecuronium (25, 50, or
Liang-Ying Liu et al.
Journal of chromatography. A, 1406, 251-257 (2015-07-01)
A method for the digestion, extraction, fractionation, and analysis of three classes of flame retardants, including 36 polybrominated diphenyl ethers (PBDEs), 9 halogenated alternative flame retardants (AFRs), and 12 organophosphate esters (OPEs) in human hair and nail samples was developed.
Mudit Vaid et al.
Clinical chemistry and laboratory medicine, 45(2), 183-186 (2007-02-22)
Distinct host immune status predisposes to different forms of pulmonary aspergillosis. Patients with chronic cavitary pulmonary aspergillosis (CCPA; n=15) or allergic bronchopulmonary aspergillosis (ABPA; n=7) of Caucasian origin were screened for single nucleotide polymorphisms (SNPs) in the collagen region of
Carla Filì et al.
Leukemia research, 76, 33-38 (2018-12-12)
The hypomethylating agent Decitabine (DAC) is a valuable treatment option in acute myeloid leukemia (AML), particularly in elderly patients (pts) not suitable for intensive chemotherapy (CHT). However, limited data are available about efficacy and safety of DAC in clinical practice.
Theodore J Angelopoulos et al.
Metabolism: clinical and experimental, 57(9), 1204-1210 (2008-08-16)
C-reactive protein (CRP) is a marker for systemic inflammation and increased cardiovascular disease risk. Regular exercise may decrease CRP. Apolipoprotein E (apo E) has 3 common genotype variants--E2/3, 3/3, and 3/4--that modulate lipid metabolism and may have other metabolic physiologic
Marina Machado Córdova et al.
Neuroscience letters, 495(3), 173-177 (2011-02-15)
The present work explored the antinociceptive effects of the flavonoid myricitrin in models of overt nociception triggered by intraplantar injection of chemical algogens into the hind paw of mice. The nociception induced by bradykinin (3 nmol/paw i.pl.) was abolished by
Pierluigi Omedè et al.
Journal of cardiovascular medicine (Hagerstown, Md.), 19(11), 650-654 (2018-09-18)
Safety and efficacy of radial and femoral access for coronary angiography performed by cardiology fellows remain to be evaluated. In this multicenter prospective study, cardiology fellows selected the access site (among femoral, right and left radial artery) for coronary angiography.
Katherine Q Philla et al.
Journal of pediatric endocrinology & metabolism : JPEM, 28(9-10), 1101-1106 (2015-05-30)
The purpose of this study was to examine the effect of chronic swallowed glucocorticoids on adrenal function during the treatment of eosinophilic esophagitis (EoE) in children. Serum cortisol levels were obtained in children with EoE pre- and post-treatment with swallowed
Jochen Springer et al.
International journal of cardiology, 168(4), 3527-3531 (2013-06-12)
Cachexia is a common complication of cancer and may be responsible for 22% of all cancer-related deaths. The exact cause of death in cancer cachexia patients is unknown. Recently, atrophy of the heart has been described in cancer cachexia animal
Piotr Moleda et al.
Kardiologia polska, 64(9), 959-965 (2006-10-21)
Left ventricular hypertrophy (LVH) is a well known risk factor of death from cardiovascular causes. Patients with type 2 diabetes mellitus are at particularly high risk of developing cardiovascular disease, which accounts for 80% of deaths in this group. Type
Bodil Salvesen et al.
Molecular immunology, 47(6), 1226-1234 (2010-01-23)
Meconium, the first intestinal discharge of the newborn, contains material accumulated during fetal life. Meconium activates complement and CD14 and may induce a systemic inflammatory response. Toll-like receptors are classical pattern-recognition receptors recognizing both exogenous and host-derived ligands. The cyanobacterial
Yu-Ki Iwasaki et al.
Journal of the American College of Cardiology, 64(19), 2013-2023 (2014-12-03)
Obstructive sleep apnea (OSA) importantly contributes to the occurrence of atrial fibrillation (AF) in humans, but the mechanisms are poorly understood. Experimental research has provided insights into AF promotion by acute OSA episodes. However, patients with OSA usually have frequent nocturnal episodes
C S John et al.
Cancer research, 55(14), 3022-3027 (1995-07-15)
The synthesis of [125I]-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide (4-[125I]BP), a novel radiopharmaceutical that possesses high affinity for both sigma-1 and sigma-2 receptor subtypes, and its binding characteristics to MCF-7 breast cancer cells are described. To obtain high yields (with high specific activity) of radioiodinated
G W Philpott et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 36(10), 1818-1824 (1995-10-01)
Detection of tumor foci may be improved by combining the selective tumor-targeting properties of a monoclonal antibody with the superior sensitivity and contrast resolution of PET. An anti-colorectal carcinoma monoclonal antibody (MAb 1A3) was labeled with 64Cu, a positron-emitting radionuclide
Young-Joo Jin et al.
Journal of clinical gastroenterology, 46(5), 420-426 (2012-04-14)
We intended to analyze the relationship between specific human leukocyte antigen (HLA)-DRB1 alleles and development of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients. A database of 468 consecutive CHB patients who received lamivudine for more than 12 months
Bodil Salvesen et al.
Molecular immunology, 47(6), 1226-1234 (2010-01-23)
Meconium, the first intestinal discharge of the newborn, contains material accumulated during fetal life. Meconium activates complement and CD14 and may induce a systemic inflammatory response. Toll-like receptors are classical pattern-recognition receptors recognizing both exogenous and host-derived ligands. The cyanobacterial
Melanie Thompson et al.
AIDS (London, England), 30(6), 869-878 (2015-12-05)
To compare the efficacy, safety, and anti-inflammatory effects of cenicriviroc (CVC), an oral, once-daily C-C chemokine receptor types 5 and 2 antagonist, with those of efavirenz (EFV) in treatment-naive, HIV-1-infected adults. A 48-week, randomized, double-blind, double-dummy phase 2b trial at
Marta Del Pino et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 28(2), 312-320 (2014-09-06)
Several high-risk human papillomavirus (HPV)-induced cell biomarkers have been proposed as possible candidates to identify patients harboring high-grade squamous intraepithelial lesions (HSILs) of the uterine cervix. We aimed to determine the feasibility of the detection of the mRNA of six
Janusz Szkodzinski et al.
Heart and vessels, 26(4), 399-407 (2010-12-04)
Many studies have suggested an imbalance between proinflammatory and anti-inflammatory markers in acute myocardial infarction (AMI). Interleukin 4 (IL-4) shows mainly anti-inflammatory activities. Interferon-gamma (IFN-γ) is a proinflammatory cytokine secreted by Th1 lymphocytes. Severe systolic left ventricular (LV) dysfunction following
Marcela Avila et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(7), 2259-2265 (2010-02-04)
The influence of the Bsm1 polymorphism of the vitamin D receptor (VDR) gene on mineral and bone disorders in chronic kidney disease (CKD) is still under discussion. The aim of this study was to analyse the relationship between VDR polymorphism
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