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Showing 1-30 of 137 results for "72586" within Papers
Peter J Rix et al.
Clinical pharmacokinetics, 54(3), 261-272 (2014-11-26)
The efficacy of nebulized sodium nitrite (AIR001) has been demonstrated in animal models of pulmonary arterial hypertension (PAH), but it was not known if inhaled nitrite would be well tolerated in human subjects at exposure levels associated with efficacy in
Francisca Rodrigues et al.
Pharmaceutical biology, 53(3), 386-394 (2014-12-05)
Currently, there is a great tendency in cosmetic area to use natural extracts. Coffee silverskin (CS) is the most abundant solid by-product generated during roasting of coffee processing. To evaluate different CS extracts as promising cosmetic ingredients, regarding antioxidant, antimicrobial
Thomas Zweckmair et al.
Journal of chromatographic science, 52(2), 169-175 (2013-02-05)
This study presents a liquid chromatography-ultraviolet (LC-UV) method for the accurate analysis of formose reaction products with regard to sum parameters. Limitations encountered in gas chromatography (e.g., thermal stability of analytes) were overcome. First, alditols are O-benzoylated and subjected to
Ryszard M Pluta
Acta neurochirurgica. Supplement, 115, 49-51 (2012-08-15)
In preclinical studies, infusion of sodium nitrite delivers nitric oxide (NO) as treatment of vasospasm after subarachnoid hemorrhage. We evaluated safety and toxicity of intravenous nitrite administration in healthy volunteers infused with increasing doses of sodium nitrite for 48 h.
Javier E Ramirez et al.
Food chemistry, 176, 106-114 (2015-01-28)
The HPLC profiles of six fruits endemic of the VIII region of Chile were investigated using high resolution mass analysis (HR-ToF-ESI-MS). The anthocyanin fingerprints generated for the fruits were compared and the antioxidant capacities measured by the scavenging of the
Xueling Cao et al.
Analytica chimica acta, 871, 43-50 (2015-04-08)
The illegal feeding of clenbuterol (CLB) to domestic animals and the potential harm of it to human health lead an urgent requirement for the efficient detection of CLB, especially in the edible meat. In this paper we reported a new
New thoughts in an old player: role of nitrite in the treatment of ischemic revascularization.
Guanghong Jia et al.
Diabetes, 63(1), 39-41 (2013-12-21)
Serena Rinaldo et al.
Biochemical and biophysical research communications, 451(3), 449-454 (2014-08-15)
The reduction of nitrite into nitric oxide (NO) in denitrifying bacteria is catalyzed by nitrite reductase. In several species, this enzyme is a heme-containing protein with one c heme and one d1 heme per monomer (cd1NiR), encoded by the nirS
Tufan Mert et al.
Inflammation, 37(5), 1814-1825 (2014-05-09)
We hypothesized that locally administrated β-adrenoreceptor agonist can modulate the inflammatory nociceptive parameters in carrageenan (CG)-induced peripheral inflammatory pain. This study was therefore aimed to assess the preventive and therapeutic effects of a β-agonist, dobutamine, by investigating its pretreatment and
Min-Fang Guo et al.
Journal of the neurological sciences, 343(1-2), 69-75 (2014-06-24)
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are autoimmune diseases characterized by the immune-mediated demyelination and neurodegeneration of the CNS. Our previous studies showed that Rho kinase inhibitor Fasudil can delay onset, and ameliorate severity of
Wendell Ho-Tin Law et al.
ChemMedChem, 9(6), 1316-1329 (2014-03-20)
We present a new class of phosphorescent cyclometalated iridium(III) bipyridyl-phenylenediamine complexes [Ir(N^C)2 (bpy-DA)](PF6 ) (bpy-DA=4-(N-(2-amino-5-methoxyphenyl)aminomethyl)-4'-methyl-2,2'-bipyridine; HN^C=2-(2,4-difluorophenyl)pyridine (Hdfppy) (1 a), 2-phenylpyridine (Hppy) (2 a), 2-phenylquinoline (Hpq) (3 a), 2-phenylcinchoninic acid methyl ester (Hpqe) (4 a)) and their triazole counterparts [Ir(N^C)2 (bpy-T)](PF6
Kraingkrai Ponhong et al.
Talanta, 133, 71-76 (2014-12-02)
A novel four-channel simultaneous injection effective mixing flow analysis (SIEMA) system has been assembled for successive determination of bilirubin and creatinine in urinary samples. The chemical variables and physical parameters in the flow system were optimized for the enhancement of
Shyamal C Bir et al.
Diabetes, 63(1), 270-281 (2013-09-07)
Nitrite anion has been demonstrated to be a prodrug of nitric oxide (NO) with positive effects on tissue ischemia/reperfusion injury, cytoprotection, and vasodilation. However, effects of nitrite anion therapy for ischemic tissue vascular remodeling during diabetes remain unknown. We examined
Sodium nitrite as a therapeutic agent for central nervous system diseases.
Ryszard M Pluta et al.
Surgical neurology, 66(1), 5-7 (2006-06-24)
Jafar Abolhasani et al.
Environmental monitoring and assessment, 187(1), 4176-4176 (2014-12-17)
Solid-phase extraction is one the most useful and efficient techniques for sample preparation, purification, cleanup, preconcentration, and determination of heavy metals at trace levels. In this paper, functionalized MCM-48 nanoporous silica with 1-(2-pyridylazo)-2-naphthol was applied for trace determination of copper
Céline Rivière et al.
Fitoterapia, 97, 253-260 (2014-06-10)
Neuroinflammatory processes are involved in the pathogenesis of many neurodegenerative disorders. Microglial cells, the main immune cells of the central nervous system, represent a target of interest to search for naturally occurring anti-inflammatory products. In this study, we evaluated the
Rasajna Nadella et al.
Journal of neuroinflammation, 11, 209-209 (2014-12-17)
The anti-inflammatory effect of the cerebral dopamine neurotrophic factor (CDNF) was shown recently in primary glial cell cultures, yet such effect remains unknown both in vivo and in 6-hydroxydopamine (6-OHDA) models of Parkinson's disease (PD). We addressed this issue by
Misako Masuda et al.
Bioscience, biotechnology, and biochemistry, 76(11), 2061-2067 (2012-11-08)
We investigated the extracellular production of folate, vitamin B(12), and thiamine in cultures of lactic acid bacteria (LAB) isolated from nukazuke, a traditional Japanese pickle, and the relationships between the vitamin production and such properties of LAB as tolerance to
Qin-Yuan Zhang et al.
Journal of biomedical materials research. Part A, 103(3), 929-938 (2014-05-24)
Nitric oxide (NO) is an important mediator in cardiovascular system to regulate vascular tone and maintain tissue homeostasis. Its role in vascular cell regulation makes it promising to address the post-surgery restenosis problem. However, the application of NO is constrained
Rustem F Dautov et al.
Nitric oxide : biology and chemistry, 40, 36-44 (2014-05-27)
Previous studies in non-human blood vessels and in platelets have demonstrated that under hypoxic conditions release of NO from nitrite (NO2(-)) is potentiated by deoxyhaemoglobin. In the current study, we characterized hypoxic potentiation of NO2(-) effects in human vasculature and
Borja Ibáñez et al.
Journal of the American College of Cardiology, 65(14), 1454-1471 (2015-04-11)
The damage inflicted on the myocardium during acute myocardial infarction is the result of 2 processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the last 3 decades, therapies to reduce ischemic injury (mainly reperfusion strategies) have been widely incorporated into
Kevin Myers et al.
Meat science, 94(1), 69-76 (2013-02-09)
The objective of this study was to determine the effect the source of added nitrite and high hydrostatic pressure (HHP) had on the growth of Listeria monocytogenes on ready-to-eat (RTE) sliced ham. Use of 600MPa HHP for 3min resulted in
Franziska Roth-Walter et al.
PloS one, 9(10), e108402-e108402 (2014-10-02)
Besides its anti-inflammatory effects, cinnamaldehyde has been reported to have anti-carcinogenic activity. Here, we investigated its impact on immune cells. Activation of nuclear factor-κB by cinnamaldehyde (0-10 µg/ml) alone or in combination with lipopolysaccharide was assessed in THP1XBlue human monocytic
W Yang et al.
European cells & materials, 27, 350-364 (2014-06-11)
In the context of skeletal tissue development and repair, endochondral ossification has inspired a new approach to regenerate bone tissue in vivo using a cartilage intermediate as an osteoinductive template. The aim of this study was to investigate the behavior
Danjun Wu et al.
Carbohydrate polymers, 119, 149-158 (2015-01-08)
Polyelectrolyte complexes (PECs) between hyaluronan (HYA) and chitosan were obtained by the one-shot addition of default amounts of polyanion to an excess of polycation. The impact of intrinsic parameters (degree of polymerization and degree of acetylation) and extrinsic parameters (charge
Piyasi Mukhopadhyay et al.
International journal of biological macromolecules, 72, 640-648 (2014-09-23)
Chitosan-alginate (CS/ALG) nanoparticles were prepared by formation of an ionotropic pre-gelation of an alginate (ALG) core entrapping insulin, followed by chitosan (CS) polyelectrolyte complexation, for successful oral insulin administration. Mild preparation process without harsh chemicals is aimed at improving insulin
Ali Jebali et al.
Drug and chemical toxicology, 37(4), 400-409 (2014-01-08)
The purpose of this research was to evaluate toxicity of uncoated magnesium oxide nanoparticles (MgO NPs), MgO NPs coated with Peanut agglutinin (PNA) lectin, and PNA alone on the promastigotes of Leishmania major (L. major) and macrophages of BALB/c mice.
Antonella M A Di Giuseppe et al.
Food chemistry, 169, 241-245 (2014-09-23)
In 2013, following the scandal of the presence of undeclared horse meat in various processed beef products across the Europe, several researches have been undertaken for the safety of consumer health. In this framework, an improved UPLC separation method has
Nagappanpillai Adarsh et al.
Analytical chemistry, 86(18), 9335-9342 (2014-08-26)
With an objective to develop optical probes for biologically important anions and neutral molecules, we synthesized three novel NIR absorbing aza-BODIPY derivatives, 3a-3c, and have systematically tuned their photophysical properties by changing the peripheral substitution. A profound red-shift was observed
Weng Kung Peng et al.
The Review of scientific instruments, 83(9), 095115-095115 (2012-10-02)
A novel, compact-sized (19 cm × 16 cm) and portable (500 g) magnetic resonance relaxometry system is designed and developed. We overcame several key engineering barriers so that magnetic resonance technology can be potentially used for disease diagnosis-monitoring in point-of-care
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