Merck
CN
Search Within

74347

Applied Filters:
Keyword:'74347'
Showing 1-30 of 113 results for "74347" within Papers
Shaik Mohammad Naushad et al.
Molecular and cellular biochemistry, 392(1-2), 273-280 (2014-03-29)
Obesity, genetic polymorphisms of xenobiotic metabolic pathway, hypermethylation of tumor suppressor genes, and hypomethylation of proapoptotic genes are known to be independent risk factors for breast cancer. The objective of this study is to evaluate the combined effect of these
N L Oliveira et al.
Blood, 79(3), 627-633 (1992-02-01)
Chronic exposure of humans to benzene has been shown to have a cytotoxic effect on hematopoietic progenitor cells in intermediate stages of differentiation, which can lead to aplastic anemia and acute myelogenous leukemia. We studied the effect of hydroquinone (HQ)
Nuan P Cheah et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(3), 1072-1081 (2013-02-19)
Tobacco smoke consists of thousands of harmful components. A major class of chemicals found in tobacco smoke is formed by aldehydes, in particular formaldehyde, acetaldehyde and acrolein. The present study investigates the gene expression changes in human lung alveolar epithelial
V V Subrahmanyam et al.
Free radical research communications, 15(5), 285-296 (1991-01-01)
Benzene, a known human myelotoxin and leukemogen is metabolized by liver cytochrome P-450 monooxygenase to phenol. Further hydroxylation of phenol by cytochrome P-450 monooxygenase results in the formation of mainly hydroquinone, which accumulates in the bone marrow. Bone marrow contains
S H Inayat-Hussain et al.
Chemico-biological interactions, 128(1), 51-63 (2000-09-21)
The hydroquinone and catechol like metabolites, NCQ344 and NCQ436 respectively, of the antipsychotic remoxipride have recently been demonstrated to induce apoptosis in myeloperoxidase (MPO)-rich human bone marrow progenitor and HL-60 cells [S.M. McGuinness, R. Johansson, J. Lundstrom, D. Ross, Induction
Jie Meng et al.
Molecular cancer therapeutics, 13(12), 3107-3122 (2014-10-04)
This study was conducted to examine the effects of doxycycline on the survival time and proliferation of hepatocellular carcinoma (HCC) in vivo and on the biologic functions of HCC in vitro. This study was also designed to evaluate the effects
Liming Zhang et al.
Journal of biomedical nanotechnology, 10(8), 1440-1449 (2014-07-16)
Although gold nanorods (GNRs) have been investigated extensively for optical hyperthermia therapies, the synthesis of rods is far from ideal. In this report, we optimized the synthesis of gold nanorods using hydroquinone as a reducing agent. Compared with the GNRs
Zoe Diana Draelos
Dermatologic therapy, 20(5), 308-313 (2007-11-30)
Skin lightening preparations are widely used in dermatology by persons of all Fitzpatrick skin types. Fitzpatrick skin types I-III require local pigment lightening for the treatment of hormonally induced melasma and postinflammatory hyperpigmentation caused by acne and trauma. Fitzpatrick skin
Se Eun Byeon et al.
Free radical biology & medicine, 57, 105-118 (2013-01-08)
The hydroxylated benzene metabolite hydroquinone (HQ) is mainly generated from benzene, an important industrial chemical, and is also a common dietary component. Although numerous papers have addressed the potential role of HQ in tumorigenic responses, the immunosuppressive and anti-inflammatory effects
Jacob Levitt
Journal of the American Academy of Dermatology, 57(5), 854-872 (2007-05-01)
Recently, the US Food and Drug Administration proposed a ban on over-the-counter hydroquinone mainly on the basis of high absorption, reports of exogenous ochronosis in humans, and murine hepatic adenomas, renal adenomas, and leukemia with large doses over extended time
J Boyle et al.
The British journal of dermatology, 114(4), 501-504 (1986-04-01)
Forty-one over-the-counter skin lightening creams were analysed for hydroquinone content, and the accuracy of tables of contents supplied with these products was assessed. Eight of the 41 were found to contain more than 2% hydroquinone, the maximum concentration permitted by
Dusan Sladić et al.
Molecules (Basel, Switzerland), 11(1), 1-33 (2007-10-27)
A review of results of bioactivity and reactivity examinations of marine sesquiterpene (hydro)quinones is presented. The article is focused mostly on friedo- rearranged drimane structural types, isolated from sponges of the order Dictyoceratida. Examples of structural correlations are outlined. Available
J J Nordlund et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 20(7), 781-787 (2006-08-11)
Hydroquinone is one of the most effective molecules for the treatment of hyperpigmentary disorders, with over 40 years of efficacy and safety data. Concerns over its safety have been raised because of the fact that it is a derivative of
Ruth A Livingstone et al.
The Journal of chemical physics, 137(18), 184304-184304 (2012-11-21)
Time-resolved photoelectron imaging was used to investigate the dynamical evolution of the initially prepared S(1) (ππ*) excited state of phenol (hydroxybenzene), catechol (1,2-dihydroxybenzene), resorcinol (1,3-dihydroxybenzene), and hydroquinone (1,4-dihydroxybenzene) following excitation at 267 nm. Our analysis was supported by ab initio
M Rendon et al.
Annales de dermatologie et de venereologie, 139 Suppl 4, S153-S158 (2013-04-03)
Hyperpigmentation has traditionally been a relatively difficult condition to treat, especially in darker racial ethnic groups. Multiple topical agents available act upon different steps of the pigmentation pathway. We review these topical agents, their mechanisms of action, and their effectiveness
Ren-Qi Wang et al.
Analytica chimica acta, 853, 608-616 (2014-12-04)
A hydrophilic interaction liquid chromatography (HILIC) method was developed to measure the composition of humic substances from river, reservoir, and treated wastewater based on their physicochemical properties. The current method fractionates the humic substances into four well-defined groups based on
Chi-Feng Hung et al.
International journal of pharmaceutics, 471(1-2), 135-145 (2014-05-27)
Intrinsic aging and photoaging modify skin structure and components, which subsequently change percutaneous absorption of topically applied permeants. The purpose of this study was to systematically evaluate drug/sunscreen permeation via young and senescent skin irradiated by ultraviolet (UV) light. Both
Richard T Penson et al.
The Lancet. Oncology, 16(3), 301-311 (2015-02-02)
GOG 240 was a practice-changing randomised phase 3 trial that concluded that chemotherapy plus bevacizumab for advanced cervical cancer significantly improves overall and progression-free survival, and the proportion of patients achieving an overall objective response, compared with chemotherapy alone. In
Mekhala Chandra et al.
Acta dermato-venereologica, 92(3), 232-235 (2011-10-18)
Post-inflammatory hyperpigmentation after acne can be as troublesome as the acne itself. Hydroquinone, a tyrosinase inhibitor, in a 4% cream can be used safely twice daily for up to 6 months to treat post-inflammatory hyperpigmentation. The efficacy of this treatment
Fanny Ramel et al.
PloS one, 10(4), e0123455-e0123455 (2015-04-04)
Although obligate anaerobe, the sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough (DvH) exhibits high aerotolerance that involves several enzymatic systems, including two membrane-bound oxygen reductases, a bd-quinol oxidase and a cc(b/o)o3 cytochrome oxidase. Effect of constant low oxygen concentration on growth and
M Yokono et al.
Nature communications, 6, 6675-6675 (2015-03-27)
Throughout the history of oxygen evolution, two types of photosystem reaction centres (PSI and PSII) have worked in a coordinated manner. The oxygen evolving centre is an integral part of PSII, and extracts an electron from water. PSI accepts the
Ayman M Atta et al.
Molecules (Basel, Switzerland), 19(5), 6246-6262 (2014-05-21)
A facile method was developed to synthesize in high yield dispersed silver nanoparticles (AgNPs) with small particle sizes of less than 10 nm. Silver nitrate was reduced to silver nanoparticles by p-chloroaniline in the presence of polyoxyethylene maleate 4-nonyl-2-propylene-phenol (NMA)
Jiyeon Yang et al.
Environmental geochemistry and health, 37(2), 321-332 (2014-09-27)
The objective of this study is to find the Cd levels in agricultural crops compared to soil, to evaluate the relationship between daily intake dose through the multimedia/multi-pathway of human exposure and biomarker levels of the residents in mine vicinity
Xiyi Li et al.
Wei sheng yan jiu = Journal of hygiene research, 33(6), 654-657 (2005-02-25)
To explore the molecular mechanism of cell response induced by hydroquinone, we investigated the protein profile after treatment with hydroquinone in human embryonic lung fibroblasts. After HQ treatment, cells were lysed in lysis solution, then the supernatant were collected and
Hydroquinone.
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 2, 691-719 (1999-09-07)
Congcong Li et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(10), 2287-2293 (2013-05-17)
Enzymes have already been extensively applied to degrade various organic pollutants in industrial wastewater, and how to improve the stability and reusability of the enzymes is critical to their practical application. In this study, poly(glycidyl methacrylate-methacrylic acid), poly(GMA-MAA), microspheres were
Carlo Foresta et al.
Human reproduction (Oxford, England), 29(6), 1134-1145 (2014-04-29)
What are the dynamics of zinc (Zn) trafficking in sperm, at the testicular, epididymal and ejaculate levels? Zn transporters are peculiarly expressed in the cells of the germ line and Zn uptake is maximal at the post-epididymal phase, where Zn
Filomena Aste Silveira et al.
Experimental and molecular pathology, 98(2), 308-311 (2015-01-13)
DNA methylation is the most important epigenetic change involved in the control of gene expression in human cells. Methylation of the p16(INK4a) gene occurs early in the development of cervical cancer. Low-grade squamous intraepithelial lesions (LSILs) are prevalent, and their
Anna Gulkowska et al.
Chemosphere, 107, 366-372 (2014-01-28)
Soil incubation experiments using (14)C-labelled sulfamethazine were carried out to assess the factors governing its nonextractable residue (NER) formation via nucleophilic addition reactions. Circumstantial evidence on possible mechanisms of NER formation was derived from a selective manipulation of soil samples.
Harishchandra Digambar Jirimali et al.
Carbohydrate polymers, 92(1), 641-644 (2012-12-12)
A redox active polymer, hydroquinone modified chitosan (Q-chitosan) was synthesized and characterized by IR and (1)H NMR spectroscopy. The nanocomposite of Q-chitosan with carbon was prepared and used to construct a stable conductive film on the electrode surface. The SEM
Page 1 of 4