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Showing 31-60 of 255 results for "75-15-0" within Papers
Diane M DellaValle et al.
Food and nutrition bulletin, 35(4), 431-439 (2015-02-03)
Iron deficiency is the most common nutrient deficiency worldwide. Large intakes of micronutrient-poor staple crops, coupled with low intakes of highly bioavailable dietary iron, are a major cause of this deficiency. To examine the concentration and relative bioavailability of iron
C J Foote et al.
Transplantation proceedings, 38(9), 2847-2849 (2006-11-23)
Single nucleotide polymorphisms (SNPs) in the multidrug resistance (MDR1) gene correlate with the intestinal function of P-glycoprotein (PGP). PGP serves as a hydrophobic export pump that extrudes cyclosporine (CsA) across the luminal membrane thus preventing CsA absorption. These genetic variants
Hong Zhang et al.
PloS one, 10(7), e0132509-e0132509 (2015-07-15)
Seed vigor is a complex property that determines the seed's potential for rapid uniform emergence and subsequent growth. However, the mechanism for change in seed vigor is poorly understood. The seeds of poplar (Populus × Canadensis Moench), which are short-lived
Yih-Horng Shiao et al.
Kidney international, 64(5), 1671-1674 (2003-10-09)
The von Hippel-Lindau (VHL) gene has been widely analyzed in many tumors. Early studies in animal tumors suggest that changes in VHL protein level and localization may be also important in tumorigenesis. In this study, we determined the role of
Rafael Rosell et al.
The Lancet. Oncology, 13(3), 239-246 (2012-01-31)
Erlotinib has been shown to improve progression-free survival compared with chemotherapy when given as first-line treatment for Asian patients with non-small-cell lung cancer (NSCLC) with activating EGFR mutations. We aimed to assess the safety and efficacy of erlotinib compared with
Xiaoyan Liao et al.
Diagnostic pathology, 15(1), 29-29 (2020-03-27)
Perianal Paget's disease (PPD) is rare and mostly described in clinical literature as case reports or small series. We investigated the clinicopathologic and immunohistochemical features of PPD in a total of 13 cases retrieved from multiple academic institutions. The median
Henrik Tønsberg et al.
The Journal of pharmacy and pharmacology, 63(6), 817-824 (2011-05-19)
The aim of this study was to examine the effects of bile on the oral absorption of the poorly water-soluble compound, halofantrine, when administered to rats in vehicles consisting of the co-solvent polyethylene glycol 400 (PEG 400) alone or in
Hector H Garcia et al.
The Lancet. Infectious diseases, 14(8), 687-695 (2014-07-08)
Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs would increase cysticidal efficacy and whether complete cyst resolution results in fewer seizures.
Luisa Benussi et al.
Neurobiology of disease, 33(3), 379-385 (2008-12-23)
Mutations in the progranulin gene (PGRN) are a major cause of frontotemporal lobar degeneration (FTLD). Herein we estimated the contribution of the PGRN Leu271LeufsX10 mutation to FTLD and related disorders in the Brescia cohort. The PGRN Leu271LeufsX10 mutation was found
Masatsugu Hiraki et al.
Annals of surgical oncology, 18(10), 3013-3019 (2011-03-17)
To assess whether gene methylation in peritoneal fluid (PF) is clinically feasible for determining micrometastasis to the peritoneum in gastric cancer. The gene methylation of BNIP3, CHFR, CYP1B1, MINT25, SFRP2, and RASSF2 were analyzed in 107 specimens of PF by
Johanne Silvain et al.
Lancet (London, England), 396(10264), 1737-1744 (2020-11-18)
Percutaneous coronary intervention (PCI)-related myonecrosis is frequent and can affect the long-term prognosis of patients. To our knowledge, ticagrelor has not been evaluated in elective PCI and could reduce periprocedural ischaemic complications compared with clopidogrel, the currently recommended treatment. The
Phaik-Leng Cheah et al.
The Malaysian journal of pathology, 28(1), 1-5 (2007-08-19)
Sixteen low grade (LSIL), 22 high grade (HSIL) squamous intraepithelial lesions, 28 invasive (13 stage I and 15 stage II-IV) squamous cell carcinoma (SCC) and 15 benign cervices were immunohistochemically studied for involvement of Bcl-2 and Bax proteins in cervical
R E Morrissey et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(12), 1315-1320 (1986-12-01)
Citreoviridin produced by the fungus Penicillium citreo-viride was administered by gavage to groups of 9-16 pregnant Fisher 344 rats either on days 8-11 (group A) or on days 12-15 (group B) of gestation. Doses of 0, 5, 10 or 15
Eric J Wagner et al.
Journal of aquatic animal health, 25(2), 125-130 (2013-05-24)
Tests were conducted to determine the concentrations of copper sulfate needed to kill Flavobacterium psychrophilum, the cause of bacterial coldwater disease, either in vitro or on Rainbow Trout Oncorhynchus mykiss eggs. For the in vitro test, a plastic strip dipped
Chia-Ying Liu et al.
Antimicrobial agents and chemotherapy, 52(9), 3161-3168 (2008-07-16)
This study reports data on the susceptibilities to five commonly used antianaerobic agents of five clinically frequently encountered anaerobes from 2000 to 2007 and to Bacteroides fragilis isolates causing nosocomial infections from 1990 to 2006. There was a trend of
Patrick Louis Cahill et al.
Biofouling, 29(8), 967-975 (2013-08-08)
Polygodial is a potent and selective inhibitor of ascidian metamorphosis that shows promise for controlling fouling by ascidians in bivalve aquaculture. The current study examined the potency of, and associated effects of seawater exposure on, a rosin-based soluble-matrix paint laced
Rachel S Kerr et al.
The Lancet. Oncology, 17(11), 1543-1557 (2016-09-24)
Antiangiogenic agents have established efficacy in the treatment of metastatic colorectal cancer. We investigated whether bevacizumab could improve disease-free survival in the adjuvant setting after resection of the primary tumour. For the open-label, randomised, controlled QUASAR 2 trial, which was
S A Pileri et al.
Histopathology, 41(1), 1-29 (2002-07-18)
Neoplasms of histiocytes and dendritic cells are rare, and their phenotypic and biological definition is incomplete. Seeking to identify antigens detectable in paraffin-embedded sections that might allow a more complete, rational immunophenotypic classification of histiocytic/dendritic cell neoplasms, the International Lymphoma
Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring p rats.
Joyce Besheer et al.
Alcoholism, clinical and experimental research, 34(12), 2044-2052 (2010-10-16)
Neuroactive steroids modulate ethanol intake in several self-administration models with variable effects. The purpose of this work was to examine the effects of the long-acting synthetic GABAergic neurosteroid ganaxolone and the endogenous neurosteroid pregnenolone, a precursor of all GABAergic neuroactive
A R La Spada et al.
Nature, 352(6330), 77-79 (1991-07-04)
X-linked spinal and bulbar muscular atrophy (Kennedy's disease) is an adult-onset form of motorneuron disease which may be associated with signs of androgen insensitivity. We have now investigated whether the androgen receptor gene on the proximal long arm of the
Junshik Hong et al.
Cancer chemotherapy and pharmacology, 67(6), 1323-1331 (2010-08-25)
To evaluate the efficacy and safety of S-1 in combination with oxaliplatin in a biweekly schedule as first-line treatment in metastatic colorectal cancer and the association between genetic polymorphisms and treatment outcomes. Eligibility included age 18-75 years, at least one
Yi-Long Wu et al.
The Lancet. Oncology, 14(8), 777-786 (2013-06-21)
The results of FASTACT, a randomised, placebo-controlled, phase 2 study, showed that intercalated chemotherapy and erlotinib significantly prolonged progression-free survival (PFS) in patients with advanced non-small-cell lung cancer. We undertook FASTACT-2, a phase 3 study in a similar patient population.
F Domergue et al.
Lipids, 35(5), 487-494 (2000-07-25)
Oleoyl-CoA elongase catalyzes four successive reactions: condensation of malonyl-CoA to oleoyl-CoA, reduction, dehydration, and another reduction. Evidence supporting this mechanism and the multienzymatic nature of the elongation complex are reported. A particulate membrane fraction from rapeseed is able to elongate
H V Ratajczak et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 27(2), 177-184 (1995-09-01)
Female B6C3F1 mice were exposed to isobutyl nitrite (IBN) by inhalation at 0, 37.5, 75, or 150 ppm for 6 hr per day, 5 days per week for 15 weeks. The potential of this compound to induce immunotoxicity was assessed
Karolina Skagen et al.
International journal of stroke : official journal of the International Stroke Society, 10(5), 730-736 (2015-01-16)
Carotid artery plaque inflammation is thought to be an important marker of plaque vulnerability and increased stroke risk. The main aim of this study was to assess the level of agreement between 2-deoxy-2-[(18)F] fluoro-D-glucose (18F-FDG) uptake on PET (positron emission
Jesus San Miguel et al.
The Lancet. Oncology, 14(11), 1055-1066 (2013-09-07)
Few effective treatments exist for patients with refractory or relapsed and refractory multiple myeloma not responding to treatment with bortezomib and lenalidomide. Pomalidomide alone has shown limited efficacy in patients with relapsed multiple myeloma, but synergistic effects have been noted
Richard T Penson et al.
The Lancet. Oncology, 16(3), 301-311 (2015-02-02)
GOG 240 was a practice-changing randomised phase 3 trial that concluded that chemotherapy plus bevacizumab for advanced cervical cancer significantly improves overall and progression-free survival, and the proportion of patients achieving an overall objective response, compared with chemotherapy alone. In
Ahmet Dursun et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 58(7), 401-405 (2009-03-04)
The association of known ACE gene and eNOS gene polymorphisms with BD in a group of Turkish patients with or without ocular involvement has been investigated. The ACE and eNOS gene polymorphisms were investigated in 73 BD patients and 90
P Lemoine et al.
Pharmacopsychiatry, 24(5), 175-179 (1991-09-01)
The efficacy of antidepressants is well established in major depressions, especially those with melancholic features. However, some anxiolytics also appear to have antidepressant properties at least for outpatients. 118 outpatients (25 males, 93 females, age: 18-60) with major depression according
C Nebbia et al.
Veterinary research communications, 21(2), 117-125 (1997-02-01)
The purpose of this study was to determine whether subchronic (70 days) oral exposure to moderate to high levels of triphenyltin acetate (TPTA), an organotin derivative used worldwide, would affect the microsomal hepatic and renal drug-metabolizing enzymes in rabbits and
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