762040

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Showing 1-17 of 17 results for "762040" within Papers

A comparative study of bioorthogonal reactions with azides.

Nicholas J Agard et al.

ACS chemical biology, 1(10), 644-648 (2006-12-19)

Detection of metabolites and post-translational modifications can be achieved using the azide as a bioorthogonal chemical reporter. Once introduced into target biomolecules, either metabolically or through chemical modification, the azide can be tagged with probes using one of three highly

Optically Transparent Dense Colloidal Gels.

Zupkauskas M, et al.

Chemical Science (2017)

Switchable supramolecular catalysis using DNA-templated scaffolds.

Garcia MAA, et al.

Chemical Communications (Cambridge, England), 52(10), 2153-2156 (2016)

Instructing cells with programmable peptide DNA hybrids.

Ronit Freeman et al.

Nature communications, 8, 15982-15982 (2017-07-12)

The native extracellular matrix is a space in which signals can be displayed dynamically and reversibly, positioned with nanoscale precision, and combined synergistically to control cell function. Here we describe a molecular system that can be programmed to control these

ATP?Responsive Aptamer?Based Metal?Organic Framework Nanoparticles (NMOFs) for the Controlled Release of Loads and Drugs.

Chen WH, et al.

Advances in Functional Materials (2017)

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones.

John C Jewett et al.

Journal of the American Chemical Society, 132(11), 3688-3690 (2010-03-02)

Bioorthogonal chemical reactions, those that do not interact or interfere with biology, have allowed for exploration of numerous biological processes that were previously difficult to study. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole

Bio-Orthogonally Crosslinked, In Situ Forming Corneal Stromal Tissue Substitute.

Hyun Jong Lee et al.

Advanced healthcare materials, 7(19), e1800560-e1800560 (2018-08-15)

In this study, an in situ forming corneal stromal substitute based on collagen type I crosslinked by bio-orthogonal strain-promoted azide-alkyne cycloaddition (SPAAC) is presented. The crosslinked collagen gel has greater transparency compared to non-crosslinked collagen gels. The mechanical properties of

Instructing cells with programmable peptide DNA hybrids.

Freeman R, et al.

Nature Communications, 8 (2017)

Strain-promoted copper-free "click" chemistry for 18F radiolabeling of bombesin.

Lachlan S Campbell-Verduyn et al.

Angewandte Chemie (International ed. in English), 50(47), 11117-11120 (2011-10-01)

Tethering Growth Factors to Collagen Surfaces Using Copper-free Click Chemistry: Surface Characterization and In Vitro Biological Response.

Lee HJ, et al.

ACS Applied Materials & Interfaces, 9(28), 23389-23399 (2017)

Profiling of Exosomal Biomarkers for Accurate Cancer Identification: Combining DNA-PAINT with Machine- Learning-Based Classification.

Chen Chen et al.

Small (Weinheim an der Bergstrasse, Germany), 15(43), e1901014-e1901014 (2019-09-04)

Exosomes are endosome-derived vesicles enriched in body fluids such as urine, blood, and saliva. So far, they have been recognized as potential biomarkers for cancer diagnostics. However, the present single-variate analysis of exosomes has greatly limited the accuracy and specificity

Copper-free click chemistry for dynamic in vivo imaging.

Jeremy M Baskin et al.

Proceedings of the National Academy of Sciences of the United States of America, 104(43), 16793-16797 (2007-10-19)

Dynamic imaging of proteins in live cells is routinely performed by using genetically encoded reporters, an approach that cannot be extended to other classes of biomolecules such as glycans and lipids. Here, we report a Cu-free variant of click chemistry

Stimuli-Responsive Nucleic Acid-Functionalized Metal-Organic-Framework Nanoparticles Using pH-and Metal-Ion Dependent DNAzymes as Locks.

Chen WH, et al.

Chemical Science (2017)

Ning, X., et al.

Angewandte Chemie (International Edition in English), 47, 2253-2255 null

DNA quadruplexes as molecular scaffolds for controlled assembly of fluorogens with aggregation-induced emission.

Longyi Zhu et al.

Chemical science, 9(9), 2559-2566 (2018-05-08)

Aggregation-induced emission (AIE) can be generated due to the restriction of intramolecular motions. The controllable assembly of fluorogens with AIE properties (AIEgens) is able to provide a new opportunity for precise manipulation of fluorescent signal transduction. Here, a tetrapod DNA

Circumvention of common labelling artefacts using secondary nanobodies.

Shama Sograte-Idrissi et al.

Nanoscale, 12(18), 10226-10239 (2020-05-02)

A standard procedure to study cellular elements is via immunostaining followed by optical imaging. This methodology typically requires target-specific primary antibodies (1.Abs), which are revealed by secondary antibodies (2.Abs). Unfortunately, the antibody bivalency, polyclonality, and large size can result in

Bio-orthogonally crosslinked hyaluronate-collagen hydrogel for suture-free corneal defect repair.

Fang Chen et al.

Biomaterials, 255, 120176-120176 (2020-06-20)

Biomaterials that mimic corneal stroma could decrease the need for donor corneal tissue and could decrease the prevalence of complications associated with corneal transplantation, including infection and rejection. We developed a bio-orthogonally crosslinked hyaluronate-collagen hydrogel which can fill corneal defects

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