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Showing 1-30 of 130 results for "77-52-1" within Papers
Micheline Grignon-Dubois et al.
Phytochemistry, 174, 112312-112312 (2020-03-21)
The invasive species Spartina anglica arose in Europe by a cross between the Afro-European species S. maritima (native, paternal ancestor) and the introduced North American S. alterniflora (invasive, maternal ancestor). Aqueous methanolic extracts were prepared from plant tissue for chemotaxonomical
Bayram Yilmaz et al.
Toxicology, 217(2-3), 184-193 (2005-10-20)
Exposure to polychlorinated biphenyls (PCBs) is known to suppress immune system function and this action is usually ascribed to dioxin-like PCBs that act via the Ah receptor. We have studied the effects of one ortho-substituted, non-dioxin-like PCB (PCB 52) and
Suleyman Sandal et al.
Mutation research, 654(1), 88-92 (2008-06-25)
Polychlorinated biphenyls (PCBs) are known to be carcinogenic, but the mechanisms of this action are uncertain. Most, but not all, studies have concluded that PCBs are not directly mutagenic, and that much if not all of the carcinogenic activity resides
Suleyman Sandal et al.
Immunopharmacology and immunotoxicology, 27(4), 601-613 (2006-01-27)
Polychlorinated biphenyls (PCBs) are industrial chemicals that have been released into the environment, resulting in widespread and persistent contamination. PCBs exist as 209 different congeners depending on the chlorine substitution on the biphenyl rings, and the physical properties and toxic
Michael S Irwig et al.
Neuroendocrinology, 80(4), 264-272 (2005-01-25)
The KiSS-1 gene codes for a family of neuropeptides called kisspeptins which bind to the G-protein-coupled receptor GPR54. To assess the possible effects of kisspeptins on gonadotropin secretion, we injected kisspeptin-52 into the lateral cerebral ventricles of adult male rats
Shahar Lavi et al.
Mayo Clinic proceedings, 83(2), 158-164 (2008-02-05)
To test the hypothesis that allelic variants of the paraoxonase-1 gene are associated with endothelial dysfunction, an early stage of atherosclerosis. We assessed 192Q>R and 55L>M allelic variants of the paraoxonase gene and coronary endothelial function in response to intracoronary
Agnieszka A Rucki et al.
Cancer research, 77(1), 41-52 (2016-11-09)
Understanding how stromal signals regulate the development of pancreatic ductal adenocarcinoma (PDAC) may suggest novel therapeutic interventions in this disease. In this study, we assessed the metastatic role of stromal signals suggested to be important in the PDAC microenvironment. Src
Sheikh M Talha et al.
BMC infectious diseases, 12, 325-325 (2012-11-29)
The Human Immunodeficiency Virus type 1 (HIV-1) envelope glycoprotein gp160, useful in detecting anti-HIV-1 antibodies, is difficult to express in heterologous hosts. The major hurdles are its signal sequence, strong hydrophobic regions and heavy glycosylation. While it has not been
Adam Dąbrowski et al.
Antioxidants (Basel, Switzerland), 9(2) (2020-02-27)
Oxidative stress underlies the pathomechanisms of toxic action of cadmium (Cd), including its damaging impact on the oral cavity. This study investigated whether the administration of an extract from Aronia melanocarpa L. berries (AME), characterized by their strong antioxidative potential
J Li et al.
Tissue antigens, 78(4), 267-270 (2011-07-08)
Two hundred and thirty-six novel human leukocyte antigen (HLA) alleles are described from volunteer donors of the China Marrow Donor Program: 71 HLA-A alleles, 79 HLA-B alleles, 43 HLA-C, 16 HLA-DRB1 alleles, 26 HLA-DQB1 and 1 HLA-DPB1. Two hundred and
Role of renal nitric oxide synthase in diabetic kidney disease during the chronic phase of diabetes.
Mogher Khamaisi et al.
Nephron. Physiology, 102(3-4), p72-p80 (2005-12-02)
Several studies have suggested that an early increase in renal nitric oxide (NO) production or activity mediates pathophysiologic and morphologic changes in diabetic nephropathy. To evaluate the role of NO in developing diabetic kidney disease, we studied the NO system
Abdelhamid Liacini et al.
Matrix biology : journal of the International Society for Matrix Biology, 21(3), 251-262 (2002-05-16)
Interleukin-1 (IL-1), the main cytokine instigator of cartilage degeneration in arthritis, induces matrix metalloproteinase-3 (MMP-3) and MMP-13 RNA and protein in chondrocytes. The molecular mechanisms of this induction were investigated with specific inhibitors of mitogen-activated protein kinase (MAPK) signaling pathways
T R Mizuta et al.
Growth factors (Chur, Switzerland), 1(1), 51-57 (1988-01-01)
We isolated the chromosomal gene for mouse interleukin-5 (IL-5) from genomic libraries using a cloned mouse IL-5 cDNA as probe. Nucleotide sequence determination of the IL-5 gene and its flanking regions showed that the gene was composed of four exons.
Andrea Gold et al.
Movement disorders : official journal of the Movement Disorder Society, 28(2), 237-240 (2013-01-31)
Alpha-synuclein (α-Syn) is immunohistochemically detectable in enteric neurons in some subjects. We determined its age distribution in the general autopsy population and in an age-matched subset investigated differences with Parkinson's (PD) and Alzheimer's diseases (AD). Archival autopsy samples of colon
Valérie Bonadona et al.
JAMA, 305(22), 2304-2310 (2011-06-07)
Providing accurate estimates of cancer risks is a major challenge in the clinical management of Lynch syndrome. To estimate the age-specific cumulative risks of developing various tumors using a large series of families with mutations of the MLH1, MSH2, and
Riyad Peeraully et al.
International urology and nephrology, 51(8), 1321-1327 (2019-06-12)
We evaluated the efficacy and safety outcomes of endoscopic intradetrusor botulinum toxin A (BTA) injections for the treatment of children with neuropathic bladder (NB) and non-neuropathic bladder (NNB) with or without detrusor overactivity in a single centre with a retrospective
Eva Barragán et al.
Haematologica, 89(8), 926-933 (2004-09-02)
The Wilms' tumor (WT1) gene is overexpressed in patients with most forms of acute leukemia. Several studies have reported the usefulness of quantitative assessment of WT1 expression as a molecular marker of minimal residual disease. However, the biological significance and
Ina Clausen et al.
Reproductive toxicology (Elmsford, N.Y.), 20(1), 47-56 (2005-04-06)
The ubiquitous toxic environmental contaminants polychlorinated biphenyls (PCBs) change gene expression in preimplantation embryos. Cell lineage-specific effects of PCB are not known. Rabbit day 6 blastocysts were exposed in vitro to low (0.1 ng/congener/mL medium) and high (1 microg) PCB
Bo Peng et al.
Zhonghua nan ke xue = National journal of andrology, 17(9), 805-808 (2011-10-04)
To investigate the inhibition of the expression of steroid receptor coactivator-1 (SRC-1) in the LNCap cell line through RNA interference (RNAi) and the effect of the silenced SRC-1 gene on LNCap cells. The experiment included four groups: siRNA transfection, siRNA
L B Hughes et al.
Genes and immunity, 5(8), 641-647 (2004-11-05)
We analyzed clinical and genetic factors contributing to infections in 457 subjects with early rheumatoid arthritis (RA) enrolled in a prospective, 1-year clinical trial of methotrexate and the TNF inhibitor etanercept. Subjects were genotyped for the following single nucleotide polymorphisms
Helen E Burrell et al.
The Journal of investigative dermatology, 128(5), 1107-1115 (2007-11-17)
In the epidermis, local and systemic factors including extracellular nucleotides and parathyroid hormone-related protein (PTHrP) regulate keratinocyte proliferation and differentiation. Extracellular nucleotides increase proliferation via activation of P2 receptors and induction of calcium transients, while endoproteases cleave PTHrP, resulting in
Hao Wang et al.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 42(1), 52-60 (2013-03-19)
To examine the spatiotemporal profiles and localization of CysLT1R, CysLT2R and GPR17 in mice with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced Parkinson disease (PD). PD model was induced by subcutaneous injection of MPTP (25 mg/kg) for 5 d in adult male
Y S Do et al.
The Journal of biological chemistry, 262(3), 1037-1043 (1987-01-25)
Renin was completely purified from human kidney cortex employing a rapid three-step procedure which included homogenization and ammonium sulfate precipitation, aminohexyl-pepstatin affinity chromatography, and affinity chromatography using a synthetic octapeptide renin inhibitor (H-77) with a reduced peptide bond (-CH2-NH- instead
Mathieu Boulin et al.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 43(11), 905-911 (2011-08-02)
There is no consensus about the most effective method for transarterial chemoembolisation of hepatocellular carcinoma. The aim of this phase II trial was to compare the efficacy and toxicity of lipiodol transarterial chemoembolisation with amiodarone in association with pirarubicin or
Dong Woo Kang et al.
Cancer research, 77(1), 142-152 (2016-10-30)
The RB1/E2F1 signaling pathway is frequently deregulated in colorectal cancer and has been suggested to intersect with Wnt/β-catenin and PI3K/Akt pathways, but molecular evidence for this link is lacking. In this study, we demonstrate that phospholipase D1 (PLD1), a transcriptional
Effectiveness of peripheral thyrotropin receptor mRNA in follow-up of differentiated thyroid cancer.
Mira Milas et al.
Annals of surgical oncology, 16(2), 473-480 (2008-11-19)
Thyroid cells in peripheral circulation have been linked to thyroid cancer (TC). These cells express thyrotropin receptor (TSHR) messenger RNA (mRNA), which has been studied as a marker of initial TC diagnosis. We examined the utility of TSHR mRNA in
Akihiro Michihara et al.
Biological & pharmaceutical bulletin, 33(9), 1471-1476 (2010-09-09)
In the present study, we investigated the dose-dependent effect of delta-tocotrienol long term (48, 72 h) on the melanin content of cells treated with delta-tocotrienol, and whether cells treated with delta-tocotrienol for long a time show cytotoxicity. We also examined
Mikkel Christensen et al.
Regulatory peptides, 163(1-3), 96-101 (2010-06-29)
This study investigated the glucagon-releasing properties of the hormones glucagon-like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) in 8 patients with type 1 diabetes mellitus (T1DM) without paracrine intraislet influence of insulin (C-peptide negative following a 5 g intravenous arginine
Theresa Lee et al.
Journal of food protection, 74(7), 1169-1174 (2011-07-12)
A total of 201 samples of brown rice, polished rice, and two types of by-products, blue-tinged rice and discolored rice, were collected from rice stores maintained at 51 rice processing complexes in Korea. These samples were analyzed for the presence
Sakhawat Hussain Rahman et al.
Digestive diseases and sciences, 50(7), 1376-1383 (2005-07-29)
Epidemiological studies have demonstrated a variety of potential environmental factors that may alter susceptibility to chronic pancreatitis (CP) through oxidative/xenobiotic stress; however, a direct causal and mechanistic role has not been established. We aimed (1) to determine the prevalence of
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