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Showing 1-30 of 97 results for "77151" within Papers
Alexandra L Klinger et al.
Biochemistry, 53(49), 7724-7734 (2014-11-11)
Structural models of the fibrils formed by the 40-residue amyloid-β (Aβ40) peptide in Alzheimer's disease typically consist of linear polypeptide segments, oriented approximately perpendicular to the long axis of the fibril, and joined together as parallel in-register β-sheets to form
J Pohl et al.
Biochemistry, 27(13), 4827-4834 (1988-06-28)
The possibility that pig pepsin has a cation binding specificity in its secondary binding subsites has been examined by the pepsin-catalyzed hydrolysis of a series of synthetic octa- to undecapeptide substrates. These chromophoric substrates are cleaved by pepsin in the
D Wang et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 83(3-4), 179-189 (2008-10-11)
Angiogenesis, or neovascularization, is known to play an important role in the neoplastic progression leading to metastasis. CD31 or Factor VIII-related antigen (F VIII RAg) immunohistochemistry is widely used in experimental studies for quantifying tumor neovascularization in immunocompromised animal models
Maria S Juchniuk de Vozzi et al.
Molecular cytogenetics, 2, 24-24 (2009-12-03)
Infertility is a natural mechanism of selection intended to prevent the delivery of a child with malformations or mental retardation. Male infertility is closely related to chromosomal abnormalities. This study was focused on the analysis of meiotic segregation involving a
Shenlin Wang et al.
The Journal of biological chemistry, 289(2), 697-707 (2013-11-23)
Multidomain protein folding is often more complex than a two-state process, which leads to the spontaneous folding of the native state. Pepsin, a zymogen-derived enzyme, without its prosegment (PS), is irreversibly denatured and folds to a thermodynamically stable, non-native conformation
Joycelyn K Quansah et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 68(1), 31-38 (2013-01-29)
The effect of thermal and ultrasonic treatment of cowpea proteins (CP) on amino acid composition, radical scavenging and reducing potential of hydrolysates (CPH) obtained from in vitro simulated gastrointestinal digestion of CP was evaluated. Hydrolysis of native and treated CP
Xinhua Windt et al.
ACS omega, 7(44), 39924-39930 (2022-11-18)
Chicken feathers are major byproducts of the livestock processing industry with high potential in the feed sector. In this study, we present a new approach using Fourier transform infrared (FTIR) spectroscopy to detect the structural changes of feather keratin and
Mahmoud-Awny Magdy et al.
European journal of pharmacology, 697(1-3), 126-131 (2012-10-12)
Ample of evidence proved the gastroprotective effect of thymoquinone (TQ), the main constituent of Nigella sativa oil; however, the full mechanistic cassette on the gastric ulcer etiopathogenesis is not fully elucidated. The aim of the present work is to unveil
R A Rocha et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 59, 104-110 (2013-06-12)
Fluoride is considered important for health because of its beneficial effect on the prevention of dental caries and on bone development in the child population. However, excessive intake has negative effects. The main pathway for exposure is oral, through consumption
Testing for laryngopharyngeal reflux in exhaled breath condensate: a pilot study.
C R Davies-Husband et al.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 37(6), 497-498 (2012-12-21)
Alexandre Minami Fioroto et al.
Journal of agricultural and food chemistry, 63(28), 6331-6337 (2015-07-03)
In vitro gastrointestinal digestion of babassu mesocarp in the absence and presence of milk and lignin was performed to evaluate the bioaccessibility of Cu, Fe, and Zn. Extractions using NaOH solutions (pH 7 and 12) were carried out to evaluate
Elizabeth A Kelly et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 150(4), 618-624 (2014-01-01)
(1) Investigate the role of reflux, specifically pepsin, in laryngopharyngeal carcinogenesis. (2) Evaluate effects of chronic pepsin exposure on cell migration, apoptosis, and colony-forming ability in hypopharyngeal cells. Translation research. Academic research laboratory. Human hypopharyngeal squamous carcinoma FaDu cells were
Moushree Pal Roy et al.
Indian journal of biochemistry & biophysics, 49(4), 266-271 (2012-10-20)
Phytases catalyze the release of phosphate from phytic acid. In this study, a phytase producing bacterial strain Shigella sp. CD2 was isolated from the wheat rhizosphere. Phytase production started from the exponential phase of bacterial growth, showing the highest activity
J Tack
Alimentary pharmacology & therapeutics, 22 Suppl 1, 48-54 (2005-07-27)
Gastro-oesophageal reflux disease is defined as the presence of symptoms or lesions that can be attributed to the reflux of gastric contents into the oesophagus. Aspiration and prolonged monitoring studies in humans have shown that reflux of gastric contents is
[Current understanding of the role of Helicobacter pylori infection in gastric carcinogenesis and the pepsin- and pepsinogen-producing function of the stomach].
M N Uspenskaia et al.
Voprosy onkologii, 51(5), 533-539 (2006-06-08)
Qiang Zou et al.
Journal of food science, 77(5), M270-M277 (2012-11-21)
Bifidobacterium bifidum F-35 was microencapsulated into whey protein microcapsules (WPMs) by a transglutaminase (TGase)-induced method after optimization of gelation conditions. The performance of these WPMs was compared with that produced by a spray drying method (WPMs-A). WPMs produced by the
Noor Akmal Syed Husain Sharifah et al.
Methods in molecular biology (Clifton, N.J.), 952, 187-196 (2012-10-27)
Fluorescence in situ hybridization (FISH) is increasingly gaining importance in clinical diagnostics settings. Due to the ability of the technique to detect chromosomal abnormalities in samples with low cellularity or containing a mixed population of cells even at a single-cell
[The role of hydrochloric acid and pepsin in the etiology of peptic ulcer].
T Mach
Przeglad lekarski, 52(1), 19-21 (1995-01-01)
J Kyle Bohman et al.
Chest, 143(5), 1407-1413 (2012-11-03)
Airway pepsin has been increasingly used as a potentially sensitive and quantifiable biomarker for gastric-to-pulmonary aspiration, despite lack of validation in normal control subjects. This study attempts to define normal levels of airway pepsin in adults and distinguish between pepsin
Gastric proteinases--structure, function, evolution and mechanism of action.
B Foltmann
Essays in biochemistry, 17, 52-84 (1981-01-01)
Takahito Yuasa et al.
The American journal of pathology, 175(5), 1993-2003 (2009-10-10)
Wnt/beta-catenin signaling is required for skeletal development and organization and for function of the growth plate and articular cartilage. To further clarify these roles and their possible pathophysiological importance, we created a new transgenic mouse model in which Wnt/beta-catenin signaling
Takafumi Mizushige et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(7), 2911-2917 (2013-04-13)
We found previously that dipeptide YL exhibits orally active anxiolytic activity comparable to diazepam. The YL sequence is often observed in the primary structure of natural food proteins. In the present study, we investigated whether YL and YL analogues are
Yi Li et al.
Environmental science and pollution research international, 20(7), 4993-5002 (2013-01-19)
The bioaccessibility of soil heavy metals is the solubility of soil heavy metals in synthetic human digestive juice, which is usually determined using in vitro digestion test. To reveal the effects of digestive enzymes on soil heavy metals bioaccessibility, three
Interaction of an amino-functionalized ionic liquid with enzymes: a fluorescence spectroscopy study.
Yunchang Fan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 105, 297-303 (2013-01-16)
The interaction of an amino-functionalized ionic liquid, 1-(2-aminoethyl)-3-butylimidazolium bromide ([NH(2)C(2)C(4)im]Br) with two enzymes, pepsin and papain was investigated using fluorescence spectroscopic technique. It is found that [NH(2)C(2)C(4)im]Br has strong ability to quench the intrinsic fluorescence of pepsin and papain. Quenching
Dragana Stanic-Vucinic et al.
Molecular nutrition & food research, 56(12), 1894-1905 (2012-10-16)
The aim of this work was to investigate the effects of high-intensity ultrasound (sonication), on the structure and allergenicity of the major cow's milk allergen, beta-lactoglobulin (BLG). Structural changes upon sonication of BLG were monitored by circular dichroism spectroscopy, tryptophan
H Cao et al.
European review for medical and pharmacological sciences, 17(11), 1427-1437 (2013-06-19)
Recently, type II collagen (CII) was found to be effective clinically for treatment of rheumatoid arthritis (RA). However, the molecular properties of CII could be changed during the preparation process. In the present study, we isolated CII from chick sternal
Sophia P Pilipchuk et al.
Journal of biomedical materials research. Part A, 101(10), 2883-2895 (2013-03-19)
Natural hydrogels have been investigated for three-dimensional tissue reconstruction and regeneration given their ability to emulate the structural complexity of multi-component extracellular matrices (ECM). Hydrogels rich in ECM can be extracted and assembled from soft tissues, retain a composition specific
Marilyn Schallom et al.
American journal of critical care : an official publication, American Association of Critical-Care Nurses, 22(5), 408-411 (2013-09-03)
Because reflux of gastric juice into the oropharynx must precede its aspiration into the lungs, it is reasonable to hypothesize that the detection of pepsin (the major gastric enzyme in gastric juice) in oral secretions may provide a relatively noninvasive
Joseph S Fruton
The Quarterly review of biology, 77(2), 127-147 (2002-07-02)
Studies on gastric digestion during 1820-1840 led to the discovery of pepsin as the agent which, in the presence of stomach acid, causes the dissolution of nutrients such as meat or coagulated egg white. Soon afterward it was shown that
Zhen-Hai Zhang et al.
Journal of biomedical nanotechnology, 9(4), 601-609 (2013-04-30)
N-octyl-N-Arginine chitosan (OACS) was synthesized in an attempt to combine the permeation enhancing effects of arginine-rich peptides and the drug loading capacity of the amphipathic polymers for insulin oral delivery. OACS self-assembled micelles of insulin were prepared by the conventional
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