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Showing 1-30 of 124 results for "79754" within Papers
Habib Bagheri et al.
Analytica chimica acta, 794, 38-46 (2013-08-27)
A novel Fe3O4-poly(aniline-naphthylamine)-based nanocomposite was synthesized by chemical oxidative polymerization process as a magnetic sorbent for micro solid phase extraction. The scanning electron microscopy images of the synthesized nanocomposite revealed that the copolymer posses a porous structure with diameters less
Young Soo Joung et al.
Nature communications, 6, 6083-6083 (2015-01-15)
Aerosols are investigated because of their significant impact on the environment and human health. To date, windblown dust and sea salt from sea spray through bursting bubbles have been considered the chief mechanisms of environmental aerosol dispersion. Here we investigate
Jae Youn Hwang et al.
Biomedical optics express, 6(1), 11-22 (2015-02-07)
We demonstrate a novel non-contact method: acoustic radiation force impulse microscopy via photoacoustic detection (PA-ARFI), capable of probing cell mechanics. A 30 MHz lithium niobate ultrasound transducer is utilized for both detection of phatoacoustic signals and generation of acoustic radiation
Epidermal growth factor receptor-targeted immunoliposomes for delivery of celecoxib to cancer cells.
Yanuar Dwi Putra Limasale et al.
International journal of pharmaceutics, 479(2), 364-373 (2015-01-18)
Cyclooxygenase-2 (COX-2) is highly expressed in many different cancers. Therefore, the inhibition of the COX-2 pathway by a selective COX-2 inhibitor, celecoxib (CLX), may be an alternative strategy for cancer prevention and therapy. Liposomal drug delivery systems can be used
Aaron C Anselmo et al.
ACS nano, 9(3), 3169-3177 (2015-02-27)
The impact of physical and chemical modifications of nanoparticles on their biological function has been systemically investigated and exploited to improve their circulation and targeting. However, the impact of nanoparticles' flexibility (i.e., elastic modulus) on their function has been explored
Daniel Soetkamp et al.
Basic research in cardiology, 109(5), 433-433 (2014-08-15)
S-nitrosation (SNO) of connexin 43 (Cx43)-formed channels modifies dye uptake in astrocytes and gap junctional communication in endothelial cells. Apart from forming channels at the plasma membrane of several cell types, Cx43 is also located at the inner membrane of
Alexander V Pichugin et al.
The American journal of pathology, 174(6), 2190-2201 (2009-05-16)
Significant host heterogeneity in susceptibility to tuberculosis exists both between and within mammalian species. Using a mouse model of infection with virulent Mycobacterium tuberculosis (Mtb), we identified the genetic locus sst1 that controls the progression of pulmonary tuberculosis in immunocompetent
Qiaoya Lin et al.
Pharmaceutical research, 31(6), 1438-1449 (2013-04-30)
Molecular therapeutics often require an effective nanoparticle-based delivery strategy to transport them to cytosolic organelles to be functional. Recently, a cytosolic delivery strategy based on the scavenger receptor class B type I (SR-BI) mediated pathway has shown great potential for
Jason J Otterstrom et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(48), E5143-E5148 (2014-11-19)
The ability of antibodies binding the influenza hemagglutinin (HA) protein to neutralize viral infectivity is of key importance in the design of next-generation vaccines and for prophylactic and therapeutic use. The two antibodies CR6261 and CR8020 have recently been shown
María José Olivares et al.
PloS one, 9(6), e99001-e99001 (2014-06-06)
The cortical actin network is dynamically rearranged during secretory processes. Nevertheless, it is unclear how de novo actin polymerization and the disruption of the preexisting actin network control transmitter release. Here we show that in bovine adrenal chromaffin cells, both
Woan-Ruoh Lee et al.
Journal of pharmaceutical sciences, 103(11), 3542-3552 (2014-09-05)
Alopecia usually cannot be cured because of the available drug therapy being unsatisfactory. To improve the efficiency of treatment, erbium-yttrium-aluminum-garnet (Er-YAG) laser treatment was conducted to facilitate skin permeation of antialopecia drugs such as minoxidil (MXD), diphencyprone (DPCP), and peptide.
M Lupi et al.
Nanotechnology, 25(33), 335706-335706 (2014-07-31)
One of the major drawbacks that limits the clinical application of nanoparticles is the lack of preliminary investigations related to their biocompatibility, biodegradability and biodistribution. In this work, biodegradable PEGylated polymer nanoparticles (NPs) have been synthesized by using macromonomers based
Sandeep Kumar Dash et al.
Journal of applied toxicology : JAT, 34(11), 1130-1144 (2014-01-31)
The aim of the present study was to develop zinc sulfide nanoparticles (ZnS NPs) and to study their cytotoxicity against the KG-1A (human acute myeloid leukemia) cell line. ZnS NPs were synthesized using the pyrolytic method and characterized by X-ray
Javad Hassanzadeh et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 107, 296-302 (2013-02-26)
A novel enhanced chemiluminescence system was developed by applying gold nanorods (Au NRs) as catalysts in rhodamine B-permanganate reaction. Au NRs with three different aspect ratios were synthesized by seed mediated growth method and characterized by UV-Vis spectra and transmission
Brett P Gross et al.
The AAPS journal, 16(6), 1194-1203 (2014-09-17)
Metastatic breast cancer is currently incurable, and available therapies are associated with severe toxicities. Induction of protective anti-tumor immunity is a promising therapeutic approach for disseminated breast cancer, as immune responses are (i) systemic; (ii) antigen-specific; and (iii) capable of
Shengnan Su et al.
Journal of hazardous materials, 244-245, 736-742 (2012-12-01)
The removal of Rhodamine B (RhB) by Co(x)Fe(3-x)O(4) magnetic nanoparticles activated Oxone has been performed in this study. A series of Co(x)Fe(3-x)O(4) nanoparticles was synthesized using a hydrothermal method. The synthetic Co(x)Fe(3-x)O(4) nanoparticles were characterized using X-ray diffraction (XRD) and
V Visconte et al.
Leukemia, 29(1), 188-195 (2014-05-24)
Perturbation in iron homeostasis is a hallmark of some hematologic diseases. Abnormal sideroblasts with accumulation of iron in the mitochondria are named ring sideroblasts (RS). RS is a cardinal feature of refractory anemia with RS (RARS) and RARS with marked
Tatsuya Murakami et al.
ACS nano, 8(7), 7370-7376 (2014-06-20)
Surface engineering of mesoscopic metal nanoparticles to increase biocompatibility and cell interaction is important for improvement of their therapeutic properties. Here, we describe a strategy to stabilize mesoscopic metal nanoparticles and to enhance their cell interaction by stepwise addition of
Roberta Martinelli et al.
Journal of cell science, 127(Pt 17), 3720-3734 (2014-07-09)
Immune cell trafficking requires the frequent breaching of the endothelial barrier either directly through individual cells ('transcellular' route) or through the inter-endothelial junctions ('paracellular' route). What determines the loci or route of breaching events is an open question with important
Songtao Cai et al.
Chemical communications (Cambridge, England), 49(8), 822-824 (2012-12-14)
A fluorescent chemosensor with high sensitivity and selectivity for palladium species based on a conjugate of phosphine and rhodamine B has been developed. The chemosensor showed an excellent palladium selectivity with a detection limit down to the 10(-9) M range
Kaliyaperumal Viswanathan et al.
Biosensors & bioelectronics, 61, 200-208 (2014-06-03)
A sensitive method for detecting hydrogen peroxide (H2O2) using rhodamine isocyanide incorporated calcium phosphate nanoparticles (Rho/CaP) was developed. The synthesized nanoparticles were characterized based on transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transformed infrared spectroscopy (FTIR), Raman spectroscopy
Masahiro Mizuno et al.
Langmuir : the ACS journal of surfaces and colloids, 31(8), 2334-2341 (2015-02-12)
A new microfluidic process was used to generate unique micrometer-sized hierarchical lipid particles having spherical lipid-core and multilamellar-shell structures. The process includes three steps: (1) formation of monodisperse droplets in a nonequilibrium state at a microchannel confluence, using a phospholipid-containing
Atul Bhardwaj et al.
Bioorganic & medicinal chemistry letters, 23(1), 163-168 (2012-12-04)
The observation that the cyclooxygenase-2 (COX-2) isozyme is over-expressed in multiple types of cancer, relative to that in adjacent non-cancerous tissue, prompted this investigation to prepare a group of hybrid fluorescent conjugates wherein the COX inhibitors ibuprofen, (S)-naproxen, acetyl salicylic
Clément Carel et al.
PloS one, 9(5), e97148-e97148 (2014-05-13)
Understanding the mechanism that controls space-time coordination of elongation and division of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is critical for fighting the tubercle bacillus. Most of the numerous enzymes involved in the synthesis of Mycolic acid
Catherine M Kelso et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 36(4), 694-700 (2014-10-14)
Introduction of microperforations in round window membrane (RWM) will allow reliable and predictable intracochlear delivery of pharmaceutical, molecular, or cellular therapeutic agents. Reliable delivery of medications into the inner ear remains a formidable challenge. The RWM is an attractive target
S Bakkialakshmi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 105, 557-562 (2013-01-29)
Fluorescence quenching of Rhodamine B base (RhB) in DMF solution has been studied at different concentrations of the amine Triethyl amine (TEA) and n-butyl amine (NBA) at room temperature. It has been observed that the fluorescence intensity of RhB decrease
Sarah D Hann et al.
Soft matter, 11(9), 1733-1738 (2015-01-21)
We study the assembly of inert and living colloids in a two-phase water-water system that provides an environment that can sustain bacteria, providing a new structure with rich potential to confine and structure microbial communities. The water-water system, formed via
Xuejuan Wan et al.
Macromolecular rapid communications, 34(4), 341-347 (2012-12-12)
The fabrication of photo-degradable, protein-polyelectrolyte complex (PPC)-coated, mesoporous silica nanoparticles (MSNs) and their controlled co-release of protein and model drugs is reported. Random copolymers composed of oligo(ethylene glycol) monomethyl ether methacrylate (OEGMA), and a photolabile o-nitrobenzyl-containing monomer, 5-(2'-(dimethylamino)ethoxy)-2-nitrobenzyl methacrylate (DENBMA)
Qi Wang et al.
Journal of hazardous materials, 246-247, 135-144 (2013-01-10)
Amorphous TiO(2) (Am-TiO(2)) was prepared at room temperature by hydrolysis of Ti(OBu)(4) in water without addition of strong acids or organic solvents. Results from XRD and TEM revealed that the as-prepared Am-TiO(2) was composed of amorphous structure. For the simultaneous
Ming Cai et al.
PloS one, 9(11), e111938-e111938 (2014-11-12)
To investigate the effects of hypoxic conditioned media from rat cerebral cortical cells on the proliferation and differentiation of neural stem cells (NSCs) in vitro, and to study the roles of PI3-K/Akt and JNK signal transduction pathways in these processes.
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