Ann. N. Y. Acad. Sci., 889, 72
(1999).
7. Dubois, R. N., Aliment Pharmacol. Ther., 14, Suppl.
1, 64 (2000).
8. Langenbach, R., et al., Cell, 83, 483 (1995).
9. O’Neill, P. O., and
equal subunits of 83 kDa; each of which contains
a flavin adenine dinucleotide (FAD) molecule.
6
Cofactor:
4
FAD, one molecule/subunit
Isoelectric point:
7
6.1
pH
.
7. Narula, N., et al., J. Cell Biol., 117, 27 (1992).
8. Oprins, A., et al., J. Cell Biol., 121, 49 (1993).
9. Whitney, J., et al., Cell, 83, 703 (1995).
10. Duden, R., et al.
., Thromb. Haemost., 42, 631-640 (1979).
15. Tokumura, A. et al., Arch. Int. Pharmacodyn., 245, 74-83 (1970).
16. Jalink, K. et al., J. Cell Biol., 126, 801-810 (1994).
Sigma warrants that its products
5. Detamore, M.S. et al., J. Oral Maxillofac. Surg., 64,
243-8 (2006).
6. Vernon, A.E., and Philpott, A., Development, 130,
71-83 (2003).
7. Yuen, M. et al., J. Clin. Invest., 124, 4693-708
(
with sensitive detection.
• Serum, plasma, and urine samples require a 64-
fold dilution in 50 mM phosphate. A suggested 64-
fold dilution is 5 µL of sample + 315 µL of Sample
Diluent.
Reagent
, J. Biol. Chem. 260, 6304-6313, (1985).
82. Y. Takeuchi et al., J. Biol. Chem., 269, 32634 (1994).
83. H. Kresse et al., Eur. J. Clin. Chem. Clin. Biochem., 32,
259 (1994).
84. A. Hildebrand et al., Biochem
, J. Biol. Chem. 260, 6304-6313, (1985).
82. Y. Takeuchi et al., J. Biol. Chem., 269, 32634 (1994).
83. H. Kresse et al., Eur. J. Clin. Chem. Clin. Biochem., 32,
259 (1994).
84. A. Hildebrand et al., Biochem
Detamore, M.S. et al., J. Oral Maxillofac.
Surg., 64, 243-8 (2006).
6. Vernon, A.E., and Philpott, A., Development,
130, 71-83 (2003).
7. Yuen, M. et al., J. Clin. Invest., 124,
4693-708 (