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Showing 1-30 of 75 results for "84-21-9" within Papers
Caroline O'Shea et al.
International journal of cancer, 105(6), 754-761 (2003-05-27)
The ADAMs (a disintegrin and metalloprotease) are membrane proteins containing both protease and adhesion domains and thus may be potentially important in cancer invasion and metastasis. The aim of our study was to investigate the distribution and potential clinical significance
Akemi Irie et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 11(8), 2962-2968 (2005-04-20)
Galectin-9, a member of the beta-galactoside-binding galectin family, induces aggregation of certain cell types. We assessed the contribution of galectin-9 to the aggregation of breast cancer cells as well as the relation between galectin-9 expression in tumor tissue and distant
A A Belaaouaj et al.
The Journal of biological chemistry, 275(35), 27123-27128 (2000-06-22)
The capacity of inflammatory cell-derived matrix metalloproteinases (MMPs) to cleave tissue factor pathway inhibitor (TFPI) and alter its activity was investigated. MMP-7 (matrilysin) rapidly cleaved TFPI to a major 35-kDa product. In contrast, MMP-1 (collagenase-1), MMP-9 (gelatinase B), and MMP-12
D Apter et al.
Clinica chimica acta; international journal of clinical chemistry, 63(2), 139-148 (1975-09-01)
A highly specific method for the determination of cortisol in human serum and urine is described. The sample is first extracted with diethyl ether/ethyl acetate (1 : 1, by vol.), then chromatographed on a highly lipophilic derivative of Sephadex (hydroxyalkoxypropyl
Ai-guo Liu et al.
Zhonghua er ke za zhi = Chinese journal of pediatrics, 47(10), 785-788 (2009-12-22)
To investigate the expression of CD147 and matrix metalloproteinase-9 (MMP-9) in children with non-Hodgkin's lymphoma (NHL) and its correlation with clinical stage, tumor size, bone marrow invasion, immunological typing, serum lactate dehydrogenase (LDH) concentration, and prognosis. Specimens excised from NHL
Anu Suomalainen et al.
The Lancet. Neurology, 10(9), 806-818 (2011-08-09)
Muscle biopsy is the gold standard for diagnosis of mitochondrial disorders because of the lack of sensitive biomarkers in serum. Fibroblast growth factor 21 (FGF-21) is a growth factor with regulatory roles in lipid metabolism and the starvation response, and
Kathryn J Gill et al.
Pharmacogenetics, 13(6), 329-338 (2003-06-05)
Individual differences in the psychomotor stimulant effects of cocaine are influenced by genetic factors. Several quantitative trait loci (QTL) have been identified for cocaine-induced locomotor activation using the AXB/BXA recombinant inbred series of strains derived from the A/J (A) and
V O Iakovenko et al.
Klinichna khirurhiia, (11)(11), 21-23 (2014-02-08)
The laterally spreading colon tumors (LST) constitute a kind of flat superficial neoplasia, which may cause colorectal cancer. There was studied the efficacy of colonoscopy and chromoscopy, using indigocarmine and acetic acid in the LST diagnosis in 897 patients. In
Hae Sang Park et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 272(10), 2969-2977 (2014-09-04)
The purpose of this study is to evaluate the feasibility of small intestinal submucosa (SIS) application on the parathyroid autotransplantation in a rat model of hypoparathyroidism. The rats were divided into four groups: NC (no procedure, n = 5), PTX
Andreas F Hottinger et al.
Annals of neurology, 70(1), 163-169 (2011-03-11)
To evaluate YKL-40 and MMP-9 proteins as tumor biomarkers in serum samples from patients with primary central nervous system lymphoma (PCNSL). In this prospective longitudinal study, serum samples from consecutive patients with histologically confirmed PCNSL were collected concurrently with magnetic
Shao-qiu Zheng et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 39(4), 240-244 (2010-07-27)
To study the expression of matrix metalloproteinase (MMP)-2, MMP-9 and vascular endothelial growth factor (VEGF)-C in breast cancer and their role in lymph node metastasis. Immunohistochemical staining was used to detect the expression of VEGF-C, MMP-2, MMP-9 and LYVE-1 in
David M Su et al.
Molecular cancer therapeutics, 8(5), 1292-1304 (2009-04-23)
Human malignant melanoma has poor prognosis because of resistance to apoptosis and therapy. We describe identification of the expression profile of 1,037 mitochondria-focused genes and 84 survival-apoptosis genes in 21 malignant melanoma cell lines and 3 normal melanocyte controls using
S M Pojda et al.
Klinika oczna, 94(1), 18-19 (1992-01-01)
21 patients (40 eyes) aged 27-84 years (15 women and 6 men) were treated orally with cavinton 3 x 5 mg, sadamine++ 3 X 75 mg, cinnarizine++ 3 X 40 mg, vit. A+E 3 X 1 caps. daily. Intramuscularly++ were
A Leyton et al.
Journal of applied microbiology, 127(4), 1069-1079 (2019-06-27)
To evaluate an aqueous extract of Macrocystis pyrifera as a nutrient source for the production of carotenoids by a marine Rhodotorula mucilaginosa isolated from seaweed samples. The effect of different culture conditions on the concentration of biomass and total pigments
Caroline Robert et al.
The Lancet. Oncology, 14(8), 733-740 (2013-06-06)
Patients with metastatic melanoma, 50% of whose tumours harbour a BRAF mutation, have a poor prognosis. Selumetinib, a MEK1/2 inhibitor, has shown antitumour activity in patients with BRAF-mutant melanoma and in preclinical models when combined with chemotherapy. This study was
R M González-Balderas et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 82(6), 1237-1246 (2020-10-16)
This study focused on the simultaneous recovery of carbohydrates (CHO) and phosphorus (P) from Desmodesmus sp. biomass cultivated in municipal wastewater, through a sequential pretreatment. The pretreatment consisted first of ultrasound to trigger cell disruption followed by ozonation to recover
M Ruhul Quddus et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 28(5), 471-476 (2009-08-22)
Surface epithelial changes (SECs) have been reported to be associated with endometrial carcinoma in about 49% of cases. They have also been seen to be associated with endometrial hyperplasia. Although morphologically benign, these lesions are considered a marker for underlying
Jeong-Hyun Kim et al.
Journal of pediatric surgery, 41(7), 1250-1254 (2006-07-05)
Hirschsprung's disease (HSCR) is a congenital abnormality that can cause an intestinal obstruction. Although HSCR demonstrates a sex-modified polygenic inheritance with contributions from multiple genes, mutations in the RET gene are believed to be the major sign of susceptibility in
R P Moody et al.
Journal of toxicology and environmental health, 20(1-2), 209-218 (1987-01-01)
The dermal penetration of 14C-ring-labeled fenitrothion and aminocarb was determined in rats and rhesus monkeys. In monkeys, 49 +/- 4% (t1/2 = 14 h) of the fenitrothion and 74 +/- 4% (t1/2 = 25 h) of aminocarb were absorbed from
A Yamada et al.
Journal of cardiovascular pharmacology, 27(1), 159-166 (1996-01-01)
Direct cardiac effects of sematilide, a new class III antiarrhythmic drug, were compared with those of E-4031 and MS-551 in canine isolated blood-perfused heart preparations. Doses of sematilide, E-4031, and MS-551 causing a 10% decrease in the spontaneous sinoatrial beating
Sandra S Wise et al.
Toxicology and applied pharmacology, 279(2), 113-118 (2014-06-22)
Sea turtles are a charismatic and ancient ocean species and can serve as key indicators for ocean ecosystems, including coral reefs and sea grass beds as well as coastal beaches. Genotoxicity studies in the species are absent, limiting our understanding
Khaled Mahmoud et al.
Transplantation, 83(8), 1035-1040 (2007-04-25)
It has been shown that hepatocyte growth factor (HGF), besides its well-established hepatotrophic effect in liver regeneration, is involved in the regeneration of the kidney after injury. In the present study we investigated whether HGF can serve as a marker
Takuya Watanabe et al.
Journal of neuropathology and experimental neurology, 68(2), 210-215 (2009-01-20)
Nijmegen breakage syndrome caused by NBS1 germline mutations is a rare autosomal recessive disease with clinical features that include microcephaly, increased radiosensitivity, and predisposition to cancer. NBS1 plays a key role in DNA double-strand break repair and the maintenance of
G Marchesini et al.
Diabetes, 50(8), 1844-1850 (2001-07-27)
Insulin sensitivity (euglycemic clamp, insulin infusion rate: 40 mU. m(-2). min(-1)) was studied in 30 subjects with biopsy-proven nonalcoholic fatty liver disease (NAFLD), normal glucose tolerance, and a BMI <30 kg/m(2). Of those 30 subjects, 9 had pure fatty liver
Lu Dong-Dong et al.
Journal of cellular and molecular medicine, 7(1), 67-71 (2003-05-28)
To investigate expression and significance of PTEN gene in primary hepatocellular carcinoma (HCC). Immunohistochemical peroxidase-conjugated streptavidin (SP) method was used to detect expression of PTEN gene in 120 cases of primary HCC and its adjacent tissue 10 cases of normal
David Cunningham et al.
Lancet (London, England), 381(9880), 1817-1826 (2013-04-26)
Dose intensification with a combination of cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) every 2 weeks improves outcomes in patients older than 60 years with diffuse large B-cell lymphoma compared with CHOP every 3 weeks. We investigated whether this survival benefit
F Nicoletti et al.
Diabetologia, 45(8), 1107-1110 (2002-08-22)
Chemokines are chemotactic cytokines controlling the recruitment of leukocytes from the blood by regulating integrin adhesiveness. It has been shown that the migration of CD4+Th1 and CD4+Th2 cells is governed by specific chemokines. Increasing evidence suggests that the CD4+Th1 cheomoattractant
Mathula Thangarajh et al.
British journal of haematology, 159(3), 352-359 (2012-09-11)
Silent cerebral infarct (SCI) is the most commonly recognized cause of neurological injury in sickle cell anaemia (SCA). We tested the hypothesis that magnetic resonance angiography (MRA)-defined vasculopathy is associated with SCI. Furthermore, we examined genetic variations in glucose-6-phosphate dehydrogenase
John W McAllister et al.
AIDS (London, England), 31(9), 1291-1295 (2017-03-17)
Completion rates for HIV postexposure prophylaxis (PEP) are often low. We investigated the adherence and safety of dolutegravir (DTG; 50 mg daily) with tenofovir disoproxil fumarate-emtricitabine (TDF-FTC; 300/200 mg, respectively) as three-drug PEP in gay and bisexual men. Open-label, single-arm study at
Alena Skálová et al.
The American journal of surgical pathology, 39(3), 338-348 (2015-01-13)
This study examines the presence of the EWSR1 rearrangement in a variety of clear cell salivary gland carcinomas with myoepithelial differentiation. A total of 94 salivary gland carcinomas with a prominent clear cell component included 51 cases of clear cell
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