850445C

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Showing 1-7 of 7 results for "850445C" within Papers

The lipid homeostasis regulation study of arenobufagin in zebrafish HepG2 xenograft model and HepG2 cells using integrated lipidomics-proteomics approach.

Li-Juan Zhao et al.

Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)

Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu

Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition.

Jeffrey K Mills et al.

Biochimica et biophysica acta, 1716(2), 77-96 (2005-10-12)

The enhanced permeability of lipid bilayer membranes at their gel-to-liquid phase transition has been explained using a "bilayer lipid heterogeneity" model, postulating leaky interfacial regions between still solid and melting liquid phases. The addition of lysolipid to dipalmitoylphosphatidylcholine bilayers dramatically

Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches.

Ségolène Hescot et al.

Oncotarget, 8(66), 109924-109940 (2018-01-05)

Mitotane (o,p'DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches as well as imaging analyses

Infection-derived lipids elicit an immune deficiency circuit in arthropods.

Dana K Shaw et al.

Nature communications, 8, 14401-14401 (2017-02-15)

The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids

Miscibility of acyl-chain defined phosphatidylcholines with N-palmitoyl sphingomyelin in bilayer membranes.

Bohdana Térová et al.

Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)

In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs

Liposomal packaging generates Wnt protein with in vivo biological activity.

Nathan T Morrell et al.

PloS one, 3(8), e2930-e2930 (2008-08-14)

Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and

Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine.

Miao-Miao Zhou et al.

Lipids in health and disease, 15(1), 135-135 (2016-08-26)

Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.

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