860815P

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Showing 1-9 of 9 results for "860815P" within Papers

Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells

Alderson NL, et al.

Journal of Lipid Research, 50(6), 1203-1208 (2009)

2'-Hydroxy ceramide in membrane homeostasis and cell signaling.

Venkatesh Kota et al.

Advances in biological regulation, 54, 223-230 (2013-10-22)

Ceramide is a precursor of complex sphingolipids and also plays important roles in cell signaling. With the advances in lipid analytical technologies, the structural diversity of ceramide species have become evident, and the complexity of cellular metabolism and function associated

Fatty acid 2-Hydroxylation in mammalian sphingolipid biology

Hama H, et al.

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1801(4), 405-414 (2010)

Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734

Herrero AB, et al.

Cancer research, 68(23), 9779-9787 (2008)

2?-Hydroxy ceramide in membrane homeostasis and cell signaling

Kota V and Hama H

Advances in Biological Regulation, 54, 223-230 (2014)

Synthesis, NMR characterization and divergent biological actions of 2'-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells.

Zdzislaw M Szulc et al.

Bioorganic & medicinal chemistry, 18(21), 7565-7579 (2010-09-21)

A straightforward method for the simultaneous preparation of (2S,3R,2'R)- and (2S,3R,2'S)-2'-hydroxy-ceramides (2'-OHCer) from (2S,3R)-sphingosine acetonide precursors and racemic mixtures of 2-hydroxy fatty acids (2-OHFAs) is described. The obtained 2'-OH-C4-, -C6-, -C12-, -C16-Cer and 2'-OH-C6-dhCer pairs of diastereoisomers were characterized thoroughly

Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734.

Ana B Herrero et al.

Cancer research, 68(23), 9779-9787 (2008-12-03)

PM02734 is a novel synthetic antitumor drug that is currently in phase I clinical trials. To gain some insight into its mode of action, we used the yeast Saccharomyces cerevisiae as a model system. Treatment of S. cerevisiae with PM02734

Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells.

Nathan L Alderson et al.

Journal of lipid research, 50(6), 1203-1208 (2009-01-28)

Sphingolipids are ubiquitous components of eukaryotic cells that regulate various cellular functions. In many cell types, a fraction of sphingolipids contain 2-hydroxy fatty acids, produced by fatty acid 2-hydroxylase (FA2H), as the N-acyl chain of ceramide [hydroxyl fatty acid (hFA)-sphingolipids].

Fatty acid 2-Hydroxylation in mammalian sphingolipid biology.

Hiroko Hama

Biochimica et biophysica acta, 1801(4), 405-414 (2009-12-23)

2-Hydroxy fatty acids (hFA) are important components of a subset of mammalian sphingolipids. The presence of hFA in sphingolipids is best described in the nervous system, epidermis, and kidney. However, the literature also indicates that various hFA-sphingolipids are present in

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