CN
Search Within
87921
Applied Filters:
Keyword:'87921'
Showing 31-60 of 174 results for "87921" within Papers
Hong-Mei Li et al.
Journal of Asian natural products research, 17(7), 761-766 (2015-01-16)
Two new abietane diterpene glycosides, wilfordosides A (1) and B (2), were isolated from the roots of Tripterygium wilfordii. The structures of compounds 1 and 2 were established using spectroscopic methods including extensive 1D and 2D NMR analysis, in combination
Ahmed Kamal et al.
Bioorganic chemistry, 59, 23-30 (2015-02-11)
A new series of C8-linked dithiocarbamate/piperazine bridged pyrrolo[2,1-c][1,4]benzodiazepine conjugates (5a-c, 6a,b) have been synthesized and evaluated for their cytotoxic potential and DNA-binding ability. The representative conjugates 5a and 5b have been screened for their cytotoxicity against a panel of 60
Yonghe Fei et al.
Food chemistry, 187, 385-390 (2015-05-16)
Three new monoterpene glycosides (1-3) and eleven known compounds (4-14) were isolated from seeds of Helianthus annuus L. (sunflower). Their structures were determined by spectroscopic and chemical methods. All the compounds were isolated from sunflower seeds for the first time.
Heath D Watts et al.
The journal of physical chemistry. B, 115(9), 1958-1970 (2011-02-16)
Coniferyl alcohol is a monomeric building block of lignin, the second most abundant biopolymer. During lignification, the monomer forms a variety of linkages through free radical additions. A large NMR database has been constructed that reports the (1)H and (13)C
Kazutaka Shibatomi et al.
Chemistry, an Asian journal, 3(8-9), 1581-1584 (2008-06-21)
The Lewis acid catalyzed bromination of aromatic side chains was achieved efficiently by using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) as the bromination reagent under mild conditions. Zirconium(IV) chloride showed the highest catalytic activity for this benzylic bromination. It was revealed that the present
Ruijian Zhong et al.
Fitoterapia, 102, 23-26 (2015-01-20)
Three new labdane-type diterpene glycosides, 15,18-di-O-β-d-glucopyranosyl-13(E)-ent-labda-7(8),13(14)-diene-3β,15,18-triol (1), 15,18-di-O-β-d-glucopyranosyl-13(E)-ent-labda-8(9),13(14)-diene-3β,15,18-triol (2), and 15-O-β-d-apiofuranosyl-(1→2)-β-d-glucopyranosyl-18-O-β-d-glucopyranosyl-13(E)-ent-labda-8(9),13(14)-diene-3β,15,18-triol (3), were isolated from the fruits of Rubus chingii. Their structures were elucidated on the basis of spectroscopic data and chemical methods. The cytotoxic activities of compounds 1-3 were
Xin Wang et al.
Nature communications, 5, 5776-5776 (2014-12-17)
In their natural habitat, bacteria are consumed by bacterivorous nematodes; however, they are not simply passive preys. Here we report a defensive mechanism used by certain bacteria to mobilize nematode-trapping fungi to kill nematodes. These bacteria release urea, which triggers
Abbas M Walji et al.
ChemMedChem, 10(2), 245-252 (2014-12-04)
Developing new antiretroviral therapies for HIV-1 infection with potential for less frequent dosing represents an important goal within drug discovery. Herein, we present the discovery of ethyl (1-((4-((4-fluorobenzyl)carbamoyl)-1-methyl-2-(2-(5-methyl- 1,3,4-oxadiazole-2-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidin-5-yl)oxy)ethyl) carbonate (MK-8970), a highly optimized prodrug of raltegravir (Isentress). Raltegravir is a
Yan Shan et al.
Chinese journal of natural medicines, 13(4), 311-315 (2015-04-25)
The present study was designed to identify potent anti-tumor compounds from a series of new longistylin C derivatives. Ten longistylin C derivatives were synthesized and their structures were confirmed by (1)H NMR, MS, and elemental analyses. Their cytotoxicity in vitro
Ying Li et al.
Journal of agricultural and food chemistry, 63(29), 6596-6602 (2015-07-07)
Rubrosterone, possessing various remarkable bioactivities, is an insect-molting C19-steroid. However, only very small amounts are available for biological tests due to its limited content from plant sources. Fungi of genus Fusarium have been reported to have the ability to convert
B E Johansson et al.
Physics in medicine and biology, 44(9), 2161-2170 (1999-09-24)
The general collection efficiency in the dielectric liquids iso-octane (CaH18; 2-2-4 trimethylpentane) and tetramethylsilane (Si(CH3)4), used as sensitive media in a thimble liquid ionization chamber (LIC) with a liquid layer thickness of 1 mm, has been studied. Measurements were made
Raphael Hoareau et al.
Journal of labelled compounds & radiopharmaceuticals, 57(13), 715-720 (2014-10-29)
We have investigated the use of cyclic sulfamidates as precursors to yield secondary amines as building blocks for subsequent reaction with carboxylic acids and acyl chlorides. The preparation of the protonated form of [(18)F]-N-(2-fluoro-ethyl)-N-methylamine from the corresponding cyclic sulfamidate proceeded
Quan Liu et al.
Journal of agricultural and food chemistry, 62(34), 8555-8561 (2014-08-05)
Weed infestation has been known to cause considerable reductions in crop yields, thereby hindering sustainable agriculture. Many plants in genus Euphorbia affect neighboring plants and other organisms by releasing chemicals into the environment. In view of the serious threat of
Xia Yin et al.
Journal of Asian natural products research, 17(8), 793-799 (2015-04-29)
Two new 3,4-seco-lanostane-type triterpenes, named as 15α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1), 5α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid 3-methyl ester (2), and one new lanostane triterpene 15α-acetoxylhydroxytrametenolic acid (3) together with a known one versisponic acid D (4) were isolated from the fruiting bodies of Laetiporus sulphureus
Amel Bouzabata et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 75, 166-172 (2014-12-03)
In Algeria, Myrtus communis L. is distributed throughout the Tell Atlas and the coastal regions of Algiers and Constantine. The leaves are used in respiratory disorders, diarrhea and hemorrhoids. The aims of this work were to evaluate the antifungal and
Tameryn Stringer et al.
Dalton transactions (Cambridge, England : 2003), 44(33), 14906-14917 (2015-08-01)
A series of mono- and bis-salicylaldimine ligands and their corresponding Rh(i) complexes were prepared. The compounds were characterised using standard spectroscopic techniques including NMR, IR spectroscopy and mass spectrometry. The salicylaldimine ligands and complexes were screened for antiparasitic activity against
Sangjun Lee et al.
Carbohydrate polymers, 121, 284-294 (2015-02-11)
In this study, we synthesized dimer acid (DA) esters, having short to long alkyl chains, (DA-Cn) by the Diels-Alder reaction and subsequent esterification reaction of fatty acids that were prepared by the hydrolysis of waste vegetable oil. It was found
Daniel C Zielinski et al.
Nature communications, 6, 7101-7101 (2015-06-10)
Drug side effects cause a significant clinical and economic burden. However, mechanisms of drug action underlying side effect pathogenesis remain largely unknown. Here, we integrate pharmacogenomic and clinical data with a human metabolic network and find that non-pharmacokinetic metabolic pathways
Giampietro Frison et al.
Rapid communications in mass spectrometry : RCM, 29(13), 1196-1204 (2015-09-24)
We describe the analytical characterization of the designer drug bk-2C-B, a cathinone derivative, contained in a seized tablet, in the absence of an analytical standard. The analytical techniques employed include gas chromatography/mass spectrometry (GC/MS), without and with derivatization with 2,2,2-trichloroethyl
Matshawandile Tukulula et al.
Pharmaceutical research, 32(8), 2713-2726 (2015-03-01)
There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would possess immunostimulatory activity, be non-cytotoxic and function
Youseung Kim et al.
Bioorganic & medicinal chemistry, 23(15), 4980-4988 (2015-06-06)
PABA/NO [O(2)-{2,4-dinitro-5-[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino) diazen-1-ium-1,2-diolate] is a nitric oxide (NO)-releasing arylating agent designed to be selectively activated by reaction with glutathione (GSH) on catalysis by glutathione S-transferase P1 (GSTP1), an enzyme frequently overexpressed in cancer cells. PABA/NO has proven active in
F Mattner et al.
Disease markers, 2015, 729698-729698 (2015-07-23)
The high affinity translocator protein (TSPO) ligand 6-chloro-2-(4'-iodophenyl)-3-(N,N-methylethyl)imidazo[1,2-a]pyridine-3-acetamide (CLINME) was radiolabelled with iodine-123 and assessed for its sensitivity for the TSPO in rodents. Moreover neuroinflammatory changes on a unilateral excitotoxic lesion rat model were detected using SPECT imaging. [(123)I]-CLINME was
Shinji Katsura et al.
Chemical & pharmaceutical bulletin, 63(8), 617-627 (2015-08-04)
The aim of this study was to identify the chemical structure of the photodegradation products of furosemide in a water-acetonitrile mixture (1 : 1). Furosemide solution was irradiated with a D65 fluorescent lamp and the products were isolated by preparative HPLC. The
The effects of Si incorporation on the electrochemical and nanomechanical properties of DLC thin films.
Papakonstantinou P, et al.
Diamond and Related Materials, 11(3-6), 1074-1080 (2002)
A Srivastava et al.
Antimicrobial agents and chemotherapy, 59(4), 2169-2178 (2015-02-04)
The discovery of quorum-sensing (QS) systems regulating antibiotic resistance and virulence factors (VFs) has afforded a novel opportunity to prevent bacterial pathogenicity. Dietary molecules have been demonstrated to attenuate QS circuits of bacteria. But, to our knowledge, no study exploring
Costyl N Njiojob et al.
Journal of medicinal chemistry, 58(6), 2845-2854 (2015-02-26)
The success of near-infrared (NIR) fluorescence to be employed for intraoperative imaging relies on the ability to develop a highly stable, NIR fluorescent, nontoxic, biocompatible, and highly excreted compound that retains a reactive functionality for conjugation to a cancer-recognizing peptide.
Delair Silveira Dos Santos et al.
Acta pharmaceutica (Zagreb, Croatia), 64(4), 495-501 (2014-12-23)
This paper describes the seasonal phytochemical variation and the antimicrobial potential of V. zizanioides roots collected in Brazil. Considering the high levels of chemical constituents and their biological activity in dichloromethane fraction, the plants were grown in different seasons and
A A Hamid et al.
Steroids, 87, 108-118 (2014-06-15)
Diosgenin has been modified to furostane derivatives after opening the F-spiroacetal ring. The aldehyde group at C26 in derivative 8 was unexpectedly transformed to the ketone 9. The structure of ketone 9 was confirmed by spectroscopy and finally by X-ray
Rowan M von Spreckelsen et al.
Scientific reports, 5, 16798-16798 (2015-11-19)
Thuja plicata is a coniferous tree which displays remarkable water channelling properties. In this article, an easily fabricated mesh inspired by the hierarchical macro surface structure of Thuja plicata branchlets is described which emulates this efficient water collection behaviour. The
Sullim Lee et al.
Natural product communications, 10(7), 1153-1158 (2015-09-29)
In the course of our search for anticancer agents based on a novel anti-austerity strategy, we found that the 70% EtOH extract of the crude drug Andrographis Herba (aerial parts of Andrographis paniculata), used in Japanese Kampo medicines, killed PANC-1
Page 2 of 6