890703C

Applied Filters:

Keyword:'890703C'

Showing 1-11 of 11 results for "890703C" within Papers

Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells.

Li Wang et al.

Molecular pharmaceutics, 4(4), 615-623 (2007-04-06)

To date, the primary approach to improving the transfection properties of cationic lipids has been the synthesis of new kinds of cationic amphipaths. Recently, however, it was found that combining two cationic lipid derivatives having the same head group but

Lipid nanoparticles for delivery of messenger RNA to the back of the eye.

Siddharth Patel et al.

Journal of controlled release : official journal of the Controlled Release Society, 303, 91-100 (2019-04-16)

Retinal gene therapy has had unprecedented success in generating treatments that can halt vision loss. However, immunogenic response and long-term toxicity with the use of viral vectors remain a concern. Non-viral vectors are relatively non-immunogenic, scalable platforms that have had

Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA.

Rumiana Koynova et al.

Biochimica et biophysica acta, 1768(2), 375-386 (2006-12-13)

Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The large magnitude of the synergy

Cationic lipids activate intracellular signaling pathways.

Caroline Lonez et al.

Advanced drug delivery reviews, 64(15), 1749-1758 (2012-05-29)

Cationic liposomes are commonly used as a transfection reagent for DNA, RNA or proteins and as a co-adjuvant of antigens for vaccination trials. A high density of positive charges close to cell surface is likely to be recognized as a

Hydrophobic moiety of cationic lipids strongly modulates their transfection activity.

Rumiana Koynova et al.

Molecular pharmaceutics, 6(3), 951-958 (2009-04-04)

Synthetic cationic lipids are widely used components of nonviral gene carriers, and the factors regulating their transfection efficiency are the subject of considerable interest. In view of the important role that electrostatic interactions with the polyanionic nucleic acids play in

Cationic liposomal lipids: from gene carriers to cell signaling.

Caroline Lonez et al.

Progress in lipid research, 47(5), 340-347 (2008-04-22)

Cationic lipids are positively charged amphiphilic molecules which, for most of them, form positively charged liposomes, sometimes in combination with a neutral helper lipid. Such liposomes are mainly used as efficient DNA, RNA or protein carriers for gene therapy or

Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency.

Boris G Tenchov et al.

Biochimica et biophysica acta, 1778(10), 2405-2412 (2008-08-30)

Synthetic cationic lipids can be used as DNA carriers and are regarded to be the most promising non-viral gene carriers. For this investigation, six novel phosphatidylcholine (PC) cationic derivatives with various hydrophobic moieties were synthesized and their transfection efficiencies for

Spectral Imaging for Microbubble Characterization.

Richard J Browning et al.

Langmuir : the ACS journal of surfaces and colloids, 36(2), 609-617 (2019-12-20)

Microbubbles stabilized by an outer lipid shell have been studied extensively for both diagnostic and therapeutic applications. The shell composition can significantly influence microbubble behavior, but performing quantitative measurements of shell properties is challenging. The aim of this study is

Effect of Glucose on the Mobility of Membrane-Adhering Liposomes.

Jurriaan J J Gillissen et al.

Langmuir : the ACS journal of surfaces and colloids, 34(1), 503-511 (2017-12-05)

Enclosed lipid bilayer structures, referred to as liposomes or lipid vesicles, have a wide range of biological functions, such as cellular signaling and membrane trafficking. The efficiency of cellular uptake of liposomes, a key step in many of these functions

Critical Synergistic Concentration of Lecithin Phospholipids Improves the Antimicrobial Activity of Eugenol against Escherichia coli.

Haoshu Zhang et al.

Applied and environmental microbiology, 83(21) (2017-08-27)

In this study, the effect of individual lecithin phospholipids on the antimicrobial properties of eugenol against Escherichia coli C600 was investigated. We tested five major phospholipids common in soy or egg lecithin (1,2-dihexadecanoyl-sn-glycero-3-phosphocholine [DPPC], 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine [DSPC], 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine [DPPE], 1,2-dihexadecanoyl-sn-glycero-3-phosphate [sodium

Head groups of lipids govern the interaction and orientation between graphene oxide and lipids

Li S, et al.

The Journal of Physical Chemistry C, 117(31), 16150-16158 (2013)

Page 1 of 1