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Showing 1-30 of 38 results for "90970" within Papers
David M Wood et al.
Drug testing and analysis, 3(7-8), 417-425 (2011-05-07)
Gamma-hydroxybutyrate (GHB) has been used as a recreational drug since the 1990s and over the last few years there has been increasing use of its analogues gamma-butyrolactone (GBL) and to a lesser extent 1,4-butanediol (1,4BD). This review will summarize the
Marina Kolomytseva et al.
Biochimica et biophysica acta, 1844(9), 1541-1549 (2014-04-29)
2-Chloromuconate cycloisomerase from the Gram-positive bacterium Rhodococcus opacus 1CP (Rho-2-CMCI) is an enzyme of a modified ortho-pathway, in which 2-chlorophenol is degraded using 3-chlorocatechol as the central intermediate. In general, the chloromuconate cycloisomerases catalyze not only the cycloisomerization, but also
Volatile compound analysis of SPME headspace and extract samples from roasted Italian chestnuts (Castanea sativa Mill.) using GC-MS
Krist S, et al.
European Food Research and Technology, 219(5), 470-473 (2004)
Leo J Schep et al.
Clinical toxicology (Philadelphia, Pa.), 50(6), 458-470 (2012-07-04)
Gamma-hydroxybutyrate (GHB) and its precursors, gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD), are drugs of abuse which act primarily as central nervous system (CNS) depressants. In recent years, the rising recreational use of these drugs has led to an increasing burden upon
Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia.
Christian Schwarzer et al.
American journal of physiology. Cell physiology, 306(9), C844-C855 (2014-03-07)
Pseudomonas aeruginosa secretes N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule to regulate gene expression. Micromolar concentrations are found in the airway surface liquid of infected lungs. Exposure of the airway surface to C12 caused a loss of transepithelial resistance within
Ryoko Taguchi et al.
American journal of physiology. Cell physiology, 307(2), C162-C168 (2014-05-23)
N-acyl-homoserine lactones (AHL) are quorum-sensing molecules in bacteria that play important roles in regulating virulence gene expression in pathogens such as Pseudomonas aeruginosa. The present study compared responses between undifferentiated and differentiated Caco-2 cells to N-(3-oxododecanoyl)-L-homoserine lactone (3-oxo-C12-HSL). A low
Petra Seibold et al.
International journal of cancer, 135(4), 923-933 (2014-01-18)
We previously reported that high concentrations of enterolactone, a lignan metabolite, are associated with lower mortality in 1,140 breast cancer patients from Germany. Using an extended set of 2,182 patients aged 50-74 years at diagnosis (2001-2005) and prospectively followed up
Charlotte Majerczyk et al.
Journal of bacteriology, 196(7), 1412-1424 (2014-01-28)
Burkholderia thailandensis contains three acyl-homoserine lactone quorum sensing circuits and has two additional LuxR homologs. To identify B. thailandensis quorum sensing-controlled genes, we carried out transcriptome sequencing (RNA-seq) analyses of quorum sensing mutants and their parent. The analyses were grounded
W Kehr et al.
Journal of neural transmission, 40(2), 129-147 (1977-01-01)
The interaction of (+)-amphetamine with haloperidol and gamma-butyrolactone on synthesis of monoamines in rat brain regions was investigated using an in vivo method, in which the accumulation of dopa and 5-hydroxytryptophan (5-HTP) was measured after inhibition of the aromatic amino
gamma-Butyrolactone.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 11, 231-239 (1976-01-01)
Simultaneous Quantification of $\gamma$-Hydroxybutyrate, $\gamma$-Butyrolactone, and 1, 4-Butanediol in Four Kinds of Beverages
Jin S, et al.
International Journal of Analytical Chemistry, 2020(1), 7-15 (2020)
Kuk-Ki Hong et al.
Journal of industrial microbiology & biotechnology, 41(10), 1517-1524 (2014-08-27)
There has been a significant global interest to produce bulk chemicals from renewable resources using engineered microorganisms. Large research programs have been launched by academia and industry towards this goal. Particularly, C4 chemicals such as succinic acid (SA) and 1,4-butanediol
Lianguo Chen et al.
Aquatic toxicology (Amsterdam, Netherlands), 157, 47-56 (2014-12-03)
SeaNine 211 with active ingredient of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) has been used as a "green" antifouling agent worldwide but has raised serious biosafety concerns in coastal environments. DCOIT has the potential to disrupt the neurotransmission in nervous system, but the underlying
M Shannon et al.
Pediatric emergency care, 16(6), 435-440 (2001-01-04)
GHB, GBL, and 1,4-BD are prevalent drugs of abuse in the United States. Unfortunately, attempts to regulate GHB have been circumvented by clandestine trafficking through the Internet and marketing of "natural" chemical precursors . Despite repeated FDA warnings to the
Chao Wang et al.
Journal of bacteriology, 196(7), 1403-1411 (2014-01-28)
Quorum sensing (QS) is a widespread mechanism of bacterial communication in which individual cells produce and respond to small chemical signals. In Agrobacterium tumefaciens, an acylhomoserine lactone-dependent QS mechanism is known to regulate the replication and conjugation of the tumor-inducing
Pascal Fuchsmann et al.
Journal of chromatography. A, 1601, 60-70 (2019-06-11)
Headspace in-tube extraction (HS-ITEX) and solid phase microextraction (HS-SPME) sampling, followed by gas chromatography-mass spectrometry (GC-MS), are widely used to analyze volatile compounds in various food matrices. While the extraction efficiency of volatile compounds from foodstuffs is crucial for obtaining
Tim Moore et al.
Biomaterials, 26(18), 3771-3782 (2005-01-01)
Recent advances in the synthesis of poly(gamma-butyrolactone) have yielded homopolymers of up to 50,000 Mw from the low-cost monomer gamma-butyrolactone. This monomer has for the better part of a century been thought impossible to polymerise. Poly(gamma-butyrolactone) displays properties that are
Determination of ?-hydroxybutyric acid (GHB) in plasma and urine by headspace solid-phase microextraction and gas chromatography/positive ion chemical ionization mass spectrometry
Frison G, et al.
Rapid Communications in Mass Spectrometry, 14(24), 2401-2407 (2000)
Maurice Dematteis et al.
La Revue du praticien, 62(5), 669-672 (2012-06-27)
Gamma-hydroxybutyric acid (GHB) is an old anaesthetic drug which was misused in the 80-90's as an anabolic agent (bodybuilding), recreational drug (drunkenness, euphoric, disinhibiting and aphrodisiac effects) and as a date rape drug (disinhibiting, hypnotic and amnesic effects). Its use
Mark A Grabiner et al.
Journal of immunology (Baltimore, Md. : 1950), 193(3), 1459-1467 (2014-07-06)
Pseudomonas aeruginosa secrete N-(3-oxododecanoyl)-homoserine lactone (HSL-C12) as a quorum-sensing molecule to regulate bacterial gene expression. Because HSL-C12 is membrane permeant, multiple cell types in P. aeruginosa-infected airways may be exposed to HSL-C12, especially adjacent to biofilms where local (HSL-C12) may
Robert B Palmer
Toxicological reviews, 23(1), 21-31 (2004-08-10)
gamma-Hydroxybutyrate (GHB) is a GABA-active CNS depressant, commonly used as a drug of abuse. In the early 1990s, the US Drug Enforcement Administration (DEA) warned against the use of GHB and restricted its sale. This diminished availability of GHB caused
H S Rosenkranz
SAR and QSAR in environmental research, 12(5), 435-444 (2002-01-30)
In this study, we use SAR approaches in an attempt to elucidate the action of gamma-butyrolactone (GBL), an illicit drug and a dietary supplement, that can cause coma and deaths in humans while exhibiting low systemic toxicity towards rodents. The
Raphaël F Canadas et al.
International journal of biological macromolecules, 71, 131-140 (2014-05-20)
This integrated study shows that waste glycerol can be bio-valorized by the fabrication of electrospun scaffolds for stem cells. Human mesenchymal stem cells (hMSC) provide an interesting model of regenerating cells because of their ability to differentiate into osteo-, chrondro-
M O Rambourg-Schepens et al.
Veterinary and human toxicology, 39(4), 234-235 (1997-08-01)
Clinical experience with toxicity induced by products containing gamma butyrolactone is limited. We report here 2 cases of gamma butyrolactone poisoning with a nail polish remover labelled "acetone-free". Rapid onset of coma, respiratory depression and bradycardia occurred in both patients.
Francesco P Busardò et al.
Current neuropharmacology, 13(1), 47-70 (2015-06-16)
The illicit recreational drug of abuse, γ-hydroxybutyrate (GHB) is a potent central nervous system depressant and is often encountered during forensic investigations of living and deceased persons. The sodium salt of GHB is registered as a therapeutic agent (Xyrem®), approved
Jin Zhang et al.
Applied and environmental microbiology, 81(3), 1071-1084 (2014-12-03)
4-Hydroxybutyryl-coenzyme A (CoA) dehydratase (4HBD) from Clostridium aminobutyricum catalyzes the reversible dehydration of 4-hydroxybutyryl-CoA to crotonyl-CoA and the irreversible isomerization of vinylacetyl-CoA to crotonyl-CoA. 4HBD is an oxygen-sensitive homotetrameric enzyme with one [4Fe-4S](2+) cluster and one flavin adenine dinucleotide (FAD)
Dietary supplement or dangerous drug? Two case reports of gamma-butyrolactone toxicity.
A H Arneson et al.
Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association, 26(5), 425-429 (2000-10-03)
Micellar electrokinetic chromatographic screening method for common sexual assault drugs administered in beverages
Bishop CS, et al.
Forensic Science International, 141(1), 7-15 (2004)
E Szirmai et al.
Die Pharmazie, 44(8), 570-571 (1989-08-01)
An analgesic activity of gamma-butyrolactone was observed and described referring to a facilitated pain killing of certain diseases.
Maria A Guimarães et al.
Journal of nanoscience and nanotechnology, 14(6), 4519-4528 (2014-04-18)
Schistosomiasis is a neglected tropical disease caused by blood flukes of the genus Schistosoma. This disease control has been widely made by praziquantel-reference drug, but resistance to this drug has already been found. There has been the finding of an
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