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Showing 1-30 of 43 results for "91-76-9" within Papers
Mellone N Marchong et al.
Molecular cancer research : MCR, 2(9), 495-503 (2004-09-24)
Retinoblastoma is initiated by loss of both RB1 alleles. Previous studies have shown that retinoblastoma tumors also show further genomic gains and losses. We now define a 2.62 Mbp minimal region of genomic loss of chromosome 16q22, which is likely
Li Zang et al.
Zhonghua yi xue za zhi, 91(20), 1408-1412 (2011-07-16)
To explore the effect of LRP (leukemia related protein) 16 on insulin resistance in C2-C12 cells and explore its molecular mechanism. Lipidosome transfection and lentivirus mediated siRNA (small interfering RNA) technology were used to establish LRP 16 overexpression and underexpression
E Restrepo-Pineda et al.
Parasitology, 135(5), 547-553 (2008-04-23)
In Colombia, Plasmodium resistance to antimalarials such as chloroquine and antifolates is a serious problem. As a result, the national Colombian health authorities are monitoring the efficacy of alternative drugs and schemes. The study of genetic polymorphisms related with drug
Jing Ping Sun et al.
International journal of cardiology, 179, 195-200 (2014-12-03)
Cardiac synchronization is important in maintaining myocardial performance, but the mechanism of diastolic dyssynchrony leading to failing myocardium is unclear. We aim to study the relation of left ventricular (LV) diastolic dyssynchrony with diastolic dysfunction in patients with hypertension. Two-D
A Titia Lely et al.
Journal of hypertension, 28(12), 2414-2421 (2010-09-11)
Renin-angiotensin-aldosterone system blockade is a cornerstone in cardiovascular protection. Angiotensin-converting enzyme (ACE)-DD genotype has been associated with resistance to angiotensin-converting enzyme inhibition (ACEi), but data are conflicting. As sodium intake modifies the effect of ACEi as well as the genotype-phenotype
Beatrice Albertini et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 40(4), 359-366 (2010-04-28)
In the present study intestinal delivery systems resistant to gastric juice, loaded with the probiotic bacteria Lactobacillus acidophilus LA14 and Bifidobacterium lactis BI07, were produced by the polyelectrolyte complexation. First, beads were prepared by the traditional extrusion method and nine
P C Molenaar
Journal of neuroimmunology, 201-202, 166-171 (2008-07-26)
The Lambert-Eaton myasthenic syndrome (LEMS) is caused by auto-antibodies that affect the activity of presynaptic calcium channels at the neuromuscular junction. Weakness in LEMS is particularly affecting the legs. Here we used leg muscles from the rolling Nagoya (RN) mouse
Thuy-Anh N Melvin et al.
American journal of rhinology & allergy, 27(1), 30-33 (2013-02-15)
Cystic fibrosis (CF) patients frequently suffer from chronic rhinosinusitis (CRS). The extent to which alterations in sinonasal innate immunity contribute to this disease process is unknown. Activation of sinonasal epithelial cell (SNEC) Toll-like receptors (TLRs), an important component of the
A J Davies et al.
Leukemia, 19(8), 1459-1465 (2005-05-20)
The role of TP53 mutation in transformation of follicular lymphoma (FL) to diffuse large B-cell lymphoma (t-FL) was examined in a panel of 91 lymph node biopsies derived from 29 patients pre- and post-transformation. The entire TP53 coding sequence was
Fiona V Cresswell et al.
The Lancet. Infectious diseases, 20(3), 308-317 (2020-01-12)
Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis. In this prospective validation study, we tested the cerebrospinal fluid
Jamie D Kapplinger et al.
Heart rhythm, 6(9), 1297-1303 (2009-09-01)
Long QT syndrome (LQTS) is a potentially lethal, highly treatable cardiac channelopathy for which genetic testing has matured from discovery to translation and now clinical implementation. Here we examine the spectrum and prevalence of mutations found in the first 2,500
Stephen A Klotz et al.
The American journal of medicine, 134(8), 1034-1038 (2021-02-26)
Arizona's rugged desert landscape harbors many venomous animals, including a small nocturnal scorpion, Centruroides sculpturatus, whose venom can cause severe neuromotor disturbance. An effective antivenom is available at selected health care facilities in the state. We analyzed 4398 calls of
Mattia Barbot et al.
Clinical endocrinology, 79(3), 394-401 (2013-01-03)
Cushing's disease (CD) has an uncertain prognosis because patients achieving remission after transsphenoidal pituitary neurosurgery (TSS) may relapse. We aimed to identify factors predicting relapse, focusing on desmopressin (DDAVP) and corticotropin-releasing hormone (CRH) tests after surgery. Fifty-seven patients with CD
Fionnuala P O'Connell et al.
American journal of clinical pathology, 121(2), 254-263 (2004-02-27)
We evaluated the immunohistochemical profile and specificity of CD138 reactivity in 238 specimens from hematopoietic and nonhematopoietic neoplasms. In 91 bone marrow biopsies, CD138 reactivity was observed for nonneoplastic plasma cells, neoplastic plasma cells in multiple myeloma cases (43/43), and
Kyoichi Kaira et al.
Annals of surgical oncology, 16(12), 3473-3481 (2009-09-25)
The purpose of this study was to evaluate the prognostic value of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in resectable non-small-cell lung cancer (NSCLC) patients with N1 and N2 nodal involvement. A total of
J Ferreira et al.
Neuropharmacology, 41(8), 1006-1012 (2001-12-19)
Experiments were designed to investigate the role of kinin B(1) and B(2) receptors in Freund's adjuvant (CFA)-induced inflammation and nociception responses by the use of B(1) and B(2) null mutant mice. Intradermal (i.d.) injection of CFA produced time-dependent and marked
Rebecca L Hull et al.
American journal of physiology. Endocrinology and metabolism, 289(4), E703-E709 (2005-05-19)
Genetic background is important in determining susceptibility to metabolic abnormalities such as insulin resistance and beta-cell dysfunction. Islet amyloid is associated with reduced beta-cell mass and function and develops in the majority of our C57BL/6J x DBA/2J (F(1)) male human
Ivana Cvetanovic et al.
American journal of therapeutics, 14(1), 25-29 (2007-02-17)
This study was design to compare the diuretic and natriuretic effects of the 2 parenteral formulations of metolazone and the combination of these 2 formulations of metolazone with the parenteral administration of furosemide. Metolazone is an anthracrene acid derivate and
Jun Zhou et al.
Environmental technology, 34(17-20), 2773-2779 (2014-02-18)
The objective of this study was to enhance removal of chemical oxygen demand (COD), total nitrogen (TN) and total phosphorus (TP) from domestic sewage in a sequencing batch reactor with added new materials. A modified anoxic/anaerobic/oxic (MAAO) process, integrating a
Ursula Ehmer et al.
Hepatology (Baltimore, Md.), 55(6), 1912-1921 (2012-01-04)
Gilbert syndrome (GS) is characterized by intermittent unconjugated hyperbilirubinemia without structural liver damage, affecting about 10% of the white population. In GS the UGT1A1*28 variant reduces bilirubin conjugation by 70% and is associated with irinotecan and protease inhibitor side effects.
Geneviève Nadeau et al.
Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 8(3-4), 118-123 (2014-05-20)
We evaluate the efficacy and safety of solifenacin to treat incontinence in children with non-neurogenic (DO) or neurogenic detrusor overactivity (NDO) refractory to oxybutinin or tolterodine. We updated and extended our previously published non-randomized uncontrolled study on open-label use of
Laurence M M Crombag et al.
The European respiratory journal, 53(2) (2018-12-24)
Guidelines recommend endosonography for mediastinal nodal staging in patients with resectable nonsmall cell lung cancer (NSCLC). We hypothesise that a systematic endobronchial ultrasound (EBUS) evaluation combined with an oesophageal investigation using the same EBUS bronchoscope (EUS-B) improves mediastinal nodal staging
Ursula Ehmer et al.
Hepatology (Baltimore, Md.), 55(6), 1912-1921 (2012-01-04)
Gilbert syndrome (GS) is characterized by intermittent unconjugated hyperbilirubinemia without structural liver damage, affecting about 10% of the white population. In GS the UGT1A1*28 variant reduces bilirubin conjugation by 70% and is associated with irinotecan and protease inhibitor side effects.
D R Lohmann et al.
American journal of human genetics, 61(2), 282-294 (1997-08-01)
In most patients with isolated unilateral retinoblastoma, tumor development is initiated by somatic inactivation of both alleles of the RB1 gene. However, some of these patients can transmit retinoblastoma predisposition to their offspring. To determine the frequency and nature of
John S Ikonomidis et al.
Circulation, 114(1 Suppl), I365-I370 (2006-07-06)
Marfan syndrome (MFS) is known to cause ascending thoracic aortic aneurysms (ATAAs). Transforming growth factor beta (TGF-beta) has recently been implicated in this process. Imbalances between the matrix metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs) have also been shown to
Dengfeng Cao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)
LIN28 has been shown to have an important role in primordial germ cell development and malignant transformation of germ cells in mouse. In this study, we examined the immunohistochemical profile of LIN28 in 131 primary human extragonadal germ cell tumors
Dengfeng Cao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)
LIN28 has been shown to have an important role in primordial germ cell development and malignant transformation of germ cells in mouse. In this study, we examined the immunohistochemical profile of LIN28 in 131 primary human extragonadal germ cell tumors
Dana Quaden et al.
Arthritis & rheumatology (Hoboken, N.J.), 72(12), 2094-2105 (2020-07-09)
This study was undertaken to identify novel autoantibodies in axial spondyloarthritis (SpA) and determine their diagnostic potential in patients with early axial SpA and controls from 2 independent cohorts. An axial SpA complementary DNA phage display library was used to
Role of neoadjuvant therapy in the multimodality treatment of older patients with pancreatic cancer.
Amanda B Cooper et al.
Journal of the American College of Surgeons, 219(1), 111-120 (2014-05-27)
A well-defined treatment strategy for elderly patients with resectable pancreatic cancer is lacking. Multiple reports have described highly selected older cancer patients who have successfully undergone pancreatectomy. However, multimodality therapy is essential for long-term survival, and elderly patients are at
Michelle Y O'Connor et al.
Metabolic syndrome and related disorders, 12(6), 347-353 (2014-05-13)
The healthy immigrant effect is a phrase that has been used for decades to describe better cardiometabolic health in African immigrants than African Americans. The recent global increase in cardiometabolic diseases raises the possibility that immigrant health may be changing.
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