91230

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Showing 1-30 of 511 results for "91230" within Papers

A Comparative In Vitro Study on the Antioxidant and Anti-acetylcholinesterase Properties of Aerial Parts of Strophanthus preusii Engl & Pax.

O A Adaramoye et al.

The West Indian medical journal, 63(5), 408-415 (2015-03-18)

To evaluate and compare the antioxidant and acetylcholinestrase (AChE)-inhibitory properties of aerial parts of Strophanthus preussii (leaves, stem and root named as SPL, SPS and SPR, respectively) while catechin served as standard. The antioxidant and AchE-inhibitory properties of the methanol

The capability of Pseudomonas aeruginosa to recruit zinc under conditions of limited metal availability is affected by inactivation of the ZnuABC transporter.

Melania D'Orazio et al.

Metallomics : integrated biometal science, 7(6), 1023-1035 (2015-03-10)

The ability of a large number of bacterial pathogens to multiply in the infected host and cause disease is dependent on their ability to express high affinity zinc importers. In many bacteria, ZnuABC, a transporter of the ABC family, plays

Epileptic seizures induce structural and functional alterations on brain tissue membranes.

Sevgi Turker et al.

Biochimica et biophysica acta, 1838(12), 3088-3096 (2014-09-10)

Epilepsy is characterized by disruption of balance between cerebral excitation and inhibition, leading to recurrent and unprovoked convulsions. Studies are still underway to understand mechanisms lying epileptic seizures with the aim of improving treatment strategies. In this context, the research

Antimicrobial and cytotoxic activities of 1,2,3-triazole-sucrose derivatives.

Krasimira T Petrova et al.

Carbohydrate research, 417, 66-71 (2015-10-04)

A library of 1-(1',2,3,3',4,4',6-hepta-O-acetyl-6'-deoxy-sucros-6'-yl)-1,2,3-triazoles have been investigated for their antibacterial, antifungal and cytotoxic activities. Most of the target compounds showed good inhibitory activity against a variety of clinically and food contaminant important microbial pathogens. In particular, 1-(1',2,3,3',4,4',6-hepta-O-acetyl-6'-deoxy-sucros-6'-yl)-4-(4-pentylphenyl)-1,2,3-triazole (5) was highly

A Phase-Variable Surface Layer from the Gut Symbiont Bacteroides thetaiotaomicron.

Mao Taketani et al.

mBio, 6(5), e01339-e01315 (2015-10-01)

The capsule from Bacteroides, a common gut symbiont, has long been a model system for studying the molecular mechanisms of host-symbiont interactions. The Bacteroides capsule is thought to consist of an array of phase-variable polysaccharides that give rise to subpopulations

Comparison of sodium dodecyl sulfate depletion techniques for proteome analysis by mass spectrometry.

Carolyn Kachuk et al.

Journal of chromatography. A, 1418, 158-166 (2015-10-01)

In proteomics, sodium dodecyl sulfate (SDS) is favored for protein solubilization and mass-based separation (e.g. GELFrEE or SDS PAGE). Numerous SDS depletion techniques are available to purify proteins ahead of mass spectrometry. The effectiveness of the purification has a controlling

Haloacetic acid removal by sequential zero-valent iron reduction and biologically active carbon degradation.

Shun Tang et al.

Chemosphere, 90(4), 1563-1567 (2012-10-20)

An innovative haloacetic acid (HAA) removal process was developed. The process consisted of a zero-valent iron (Fe(0)) column followed by a biologically active carbon (BAC) column that were efficient in degrading tri- and di-HAAs, and mono- and di-HAAs, respectively. The

Differential Protein Expression in Congenital and Acquired Cholesteatomas.

Seung-Ho Shin et al.

PloS one, 10(9), e0137011-e0137011 (2015-09-04)

Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intact eardrum. Congenital and acquired cholesteatomas progress quite differently from each other and progress patterns can provide clues about the unique origin and pathogenesis of the abnormality.

Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of β2-Adrenergic Receptors.

Luis E Gimenez et al.

Molecular pharmacology, 87(6), 954-964 (2015-03-19)

Salmeterol is a long-acting β2-adrenergic receptor (β2AR) agonist that is widely used as a bronchodilator for the treatment of persistent asthma and chronic obstructive pulmonary disease in conjunction with steroids. Previous studies demonstrated that salmeterol showed weak efficacy for activation

Anti-glycation activities of phenolic constituents from Silybum marianum (Milk Thistle) flower in vitro and on human explants.

Seoungwoo Shin et al.

Molecules (Basel, Switzerland), 20(3), 3549-3564 (2015-02-24)

Glycation is an ageing reaction of naturally occurring sugars with dermal proteins, with clinical signs appearing in vivo around age 30, and increasing steadily/regularly with age. The suppleness of the dermis is affected by the formation of bridges between proteins

Orally administrated pterostilbene attenuates acute cerebral ischemia-reperfusion injury in a dose- and time-dependent manner in mice.

Yu Zhou et al.

Pharmacology, biochemistry, and behavior, 135, 199-209 (2015-06-19)

Pterostilbene (3,5-dimethoxy-4-hydroxystilbene) is a component of blueberry. It has been reported that long-term treatment with blueberry has a neuroprotective effect. However, it has not been reported whether pterostilbene is effective in attenuating cerebral ischemia/reperfusion (I/R) injury. In the present study

In vitro performance of lipid-PLGA hybrid nanoparticles as an antigen delivery system: lipid composition matters.

Yun Hu et al.

Nanoscale research letters, 9(1), 434-434 (2014-09-19)

Due to the many beneficial properties combined from both poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) and liposomes, lipid-PLGA hybrid NPs have been intensively studied as cancer drug delivery systems, bio-imaging agent carriers, as well as antigen delivery vehicles. However, the impact

Expression of NAT2 in immune system cells and the relation of NAT2 gene polymorphisms in the anti-tuberculosis therapy in Mexican mestizo population.

R Salazar-González et al.

Molecular biology reports, 41(12), 7833-7843 (2014-08-29)

Arylamine N-acetyltransferase 2 (NAT2) metabolizes isoniazid (INH) and Single Nucleotide Polymorphisms (SNP) responsible for its activity has been reported. The aim of this study in the Mexican mestizo population was to evaluate NAT2 expression at the protein level in immune

Volatile compounds and antioxidant capacity of the bio-oil obtained by pyrolysis of Japanese red pine (pinus densiflora siebold and zucc.).

Jayanta Kumar Patra et al.

Molecules (Basel, Switzerland), 20(3), 3986-4006 (2015-03-05)

In the present study, sawdust bio-oil (SBO) manufactured by fast pyrolysis of Japanese red pine (Pinus densiflora Siebold and Zucc.) sawdust was analyzed for its volatile chemical compound composition and evaluated for its free radical scavenging potential, inhibition of lipid

Lack of reversal of oxidative damage in renal tissues of lead acetate-treated rats.

Ademola Adetokunbo Oyagbemi et al.

Environmental toxicology, 30(11), 1235-1243 (2014-04-08)

Removal of lead from the environment of man or otherwise, the movement of man from lead-contaminated areas has been employed as a means of abatement of the toxic effects of lead. Whether toxic effects in already-exposed individuals subside after lead

Coupling of solid phase microextraction with electrospray ionization ion mobility spectrometry and direct analysis of venlafaxine in human urine and plasma.

Mohammad T Jafari et al.

Analytica chimica acta, 853, 460-468 (2014-12-04)

The capability of electrospray ionization-conventional ion mobility spectrometry (ESI-IMS) for direct analysis of the samples extracted by solid phase microextraction (SPME) was investigated and evaluated for the first time. To that end, an appropriate new desorption chamber was designed and

Comparative Analysis of Defense Responses in Chocolate Spot-Resistant and -Susceptible Faba Bean (Vicia faba) Cultivars Following Infection by the Necrotrophic Fungus Botrytis fabae.

Mahmoud H El-Komy

The plant pathology journal, 30(4), 355-366 (2014-12-17)

In this study, resistance responses were investigated during the interaction of Botrytis fabae with two faba bean cultivars expressing different levels of resistance against this pathogen, Nubaria (resistant) and Giza 40 (susceptible). Disease severity was assessed on leaves using a

Release of copper from embedded solid copper bullets into muscle and fat tissues of fallow deer (Dama dama), roe deer (Capreolus capreolus), and wild boar (Sus scrofa) and effect of copper content on oxidative stability of heat-processed meat.

I Schuhmann-Irschik et al.

Meat science, 108, 21-27 (2015-05-26)

When venison with embedded copper bullets was subjected to different culinary processing procedures, the amount of copper released from the embedded bullet was affected more by the retention period of the bullet in the meat during cool storage, than by

Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling.

Yong-Seok Han et al.

Biomolecules & therapeutics, 23(3), 225-232 (2015-05-23)

We identified a novel Akt signaling mechanism that mediates fucoidan-induced suppression of human colon cancer cell (HT29) proliferation and anticancer effects. Fucoidan treatment significantly inhibited growth, induced G1-phase-associated upregulation of p21WAF1 expression, and suppressed cyclin and cyclin-dependent kinase expression in

Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function.

Alan Mortensen et al.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)

The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these

Stable chlorine isotope analysis of chlorinated acetic acids using gas chromatography/quadrupole mass spectrometry.

Milena E Miska et al.

Rapid communications in mass spectrometry : RCM, 29(24), 2341-2348 (2015-11-14)

The environmental occurrence of chlorinated acetic acids (CAAs) has been extensively studied, but the sources and transport are still not yet fully understood. A promising approach for source apportionment and process studies is the isotopic characterization of target compounds. We

Generation of Redox Imbalance Mediates the Cytotoxic Effect of Malabaricone-A in a Multidrug Resistant Cell Line.

Alak Manna et al.

Anti-cancer agents in medicinal chemistry, 15(9), 1156-1163 (2015-06-03)

Multidrug resistance (MDR) refers to cross-resistance to a range of structurally and functionally unrelated compounds, and is accompanied by an elevated expression of ATP driven cell-membrane transporters. The cytotoxicity of Malabaricone-A (MAL-A), a diarylnonanoid derived from Myristica malabarica was demonstrated

In vitro antioxidant activity and GC-MS analysis of the ethanol and aqueous extracts of Cissus cornifolia (Baker) Splanch (Vitaceae) parts.

Talent Chipiti et al.

Acta poloniae pharmaceutica, 72(1), 119-127 (2015-04-09)

The study was intended to explore the antioxidant potential and phytochemical content of the ethanol and aqueous extracts of the leaf and root samples of Cissus cornifolia (Baker) Splanch (Vitaceae) across a series of four in vitro models. The results

Identification and characterization of a peculiar vtx2-converting phage frequently present in verocytotoxin-producing Escherichia coli O157 isolated from human infections.

Rosangela Tozzoli et al.

Infection and immunity, 82(7), 3023-3032 (2014-05-07)

Certain verocytotoxin-producing Escherichia coli (VTEC) O157 phage types (PTs), such as PT8 and PT2, are associated with severe human infections, while others, such as PT21, seem to be restricted to cattle. In an attempt to delve into the mechanisms underlying

Association of inflammatory response and oxidative injury in the pathogenesis of liver steatosis and insulin resistance following subchronic exposure to malathion in rats.

Mohamed Montassar Lasram et al.

Environmental toxicology and pharmacology, 38(2), 542-553 (2014-09-03)

Insulin resistance and risk of type 2 diabetes are the most important complications following exposure to organophosphorous (OPs) pesticides. Regarding the importance of liver on metabolic pathways regulation, in particular blood glucose homeostasis, we focused on liver inflammation and oxidative

Distinct dictation of Japanese encephalitis virus-induced neuroinflammation and lethality via triggering TLR3 and TLR4 signal pathways.

Young Woo Han et al.

PLoS pathogens, 10(9), e1004319-e1004319 (2014-09-05)

Japanese encephalitis (JE) is major emerging neurologic disease caused by JE virus. To date, the impact of TLR molecules on JE progression has not been addressed. Here, we determined whether each TLR modulates JE, using several TLR-deficient mouse strains (TLR2

Evaluation of small noncoding RNAs in ex vivo stored human mature red blood cells: changes in noncoding RNA levels correlate with storage lesion events.

Tewarit Sarachana et al.

Transfusion, 55(11), 2672-2683 (2015-07-16)

While biomarkers of storage lesions (SLs) for red blood cells (RBCs) abound, the physiologic consequences of SLs and associated important events are poorly understood. Previously we have identified differentially expressed regulatory small noncoding RNAs (ncRNAs) in stored RBCs, suggesting their

Antioxidant Effects of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius) on Multiple Free Radical and Reducing Power Assays, Especially on Different Superoxide Anion Radical Generation Systems.

Shintaro Sugahara et al.

Journal of food science, 80(11), C2420-C2429 (2015-10-13)

Yacon (Smallanthus sonchifolius), a native Andean plant, has been cultivated as a crop and locally used as a traditional folk medicine for the people suffering from diabetes and digestive/renal disorders. However, the medicinal properties of this plant and its processed

Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage.

Khadijeh Jamialahmadi et al.

Environmental toxicology and pharmacology, 38(1), 212-219 (2014-06-25)

Glucosamine (GlcN) is an important precursor in the biochemical synthesis of glycosylated proteins and lipids in human body. It gains importance because of its contribution to human health and its multiple biological and therapeutic effects. In this study, the in

Protective Effects of Ferulic Acid on High Glucose-Induced Protein Glycation, Lipid Peroxidation, and Membrane Ion Pump Activity in Human Erythrocytes.

Weerachat Sompong et al.

PloS one, 10(6), e0129495-e0129495 (2015-06-09)

Ferulic acid (FA) is the ubiquitous phytochemical phenolic derivative of cinnamic acid. Experimental studies in diabetic models demonstrate that FA possesses multiple mechanisms of action associated with anti-hyperglycemic activity. The mechanism by which FA prevents diabetes-associated vascular damages remains unknown.

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